Mutations human cancers cancer aurora kinases. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Spindle Apparatus HeLa Cells Tumor Cells, Cultured Cell Line Kinetochores Centrosome Microtubules HCT116 Cells Cells, Cultured Blastodisc Cell Nucleus Fibroblasts Centromere Neoplastic Stem Cells

Organisms4

Mice, Nude Mice, SCID Potoroidae Mice, Transgenic

Diseases30

Neoplasms Breast Neoplasms Ovarian Neoplasms Lung Neoplasms Prostatic Neoplasms Colonic Neoplasms Cell Transformation, Neoplastic Stomach Neoplasms Neoplasm Invasiveness Neoplasm Metastasis Pancreatic Neoplasms Genetic Predisposition to Disease Polyploidy Colorectal Neoplasms Carcinoma Disease Progression Carcinoma, Squamous Cell Carcinoma, Non-Small-Cell Lung Chondroma Urinary Bladder Neoplasms Uterine Cervical Neoplasms Adenocarcinoma Chromosomal Instability Endometrial Neoplasms Liver Neoplasms Neoplasm Recurrence, Local Rectal Neoplasms Esophageal Neoplasms Skin Neoplasms Disease Models, Animal

Chemicals and Drugs88

Aurora Kinases Aurora Kinase A Aurora Kinase B Aurora Kinase C Protein-Serine-Threonine Kinases Protein Kinase Inhibitors Phosphatidylinositol 3-Kinases Protein Kinases Antineoplastic Agents Cell Cycle Proteins Neoplasm Proteins RNA, Small Interfering RNA, Messenger Piperazines Tumor Suppressor Protein p53 src-Family Kinases Calcium-Calmodulin-Dependent Protein Kinases Benzamides Nuclear Proteins Proto-Oncogene Proteins Organophosphates Azepines Microtubule-Associated Proteins Pyrimidines Enzyme Inhibitors DNA-Binding Proteins Quinazolines Histones Protein Kinase C Tumor Markers, Biological p38 Mitogen-Activated Protein Kinases Cyclic AMP-Dependent Protein Kinases Transcription Factors Mitogen-Activated Protein Kinase 1 DNA, Neoplasm Protein-Tyrosine Kinases Pyrazoles Cancer Vaccines Tumor Suppressor Proteins DNA Primers p21-Activated Kinases Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinase 3 Proto-Oncogene Proteins c-akt CDC2 Protein Kinase Cyclin-Dependent Kinases Aneugens Chromosomal Proteins, Non-Histone Receptor, Epidermal Growth Factor Collagen Type XI Receptor Protein-Tyrosine Kinases Membrane Proteins Intracellular Signaling Peptides and Proteins Recombinant Proteins Extracellular Signal-Regulated MAP Kinases MAP Kinase Kinase Kinases Isoenzymes Receptor, erbB-2 Carrier Proteins Paclitaxel Recombinant Fusion Proteins Receptors, Estrogen Casein Kinase II Creatine Kinase Adaptor Proteins, Signal Transducing Mitogen-Activated Protein Kinases Antineoplastic Agents, Phytogenic DNA MAP Kinase Kinase 1 Thymidine Kinase Ribosomal Protein S6 Kinases eIF-2 Kinase Pyruvate Kinase TOR Serine-Threonine Kinases Phosphoproteins Glycogen Synthase Kinase 3 Proteins MAP Kinase Kinase 4 Casein Kinases Indoles Thiazoles Phosphotransferases (Alcohol Group Acceptor)Antigens, Neoplasm Imidazoles Pyridines Antibodies, Monoclonal Serine

Analytical, Diagnostic and Therapeutic Techniques and Equipment47

Early Detection of Cancer Blotting, Western Xenograft Model Antitumor Assays Reverse Transcriptase Polymerase Chain Reaction Transfection Gene Expression Profiling Polymerase Chain Reaction Drug Screening Assays, Antitumor Models, Biological Pedigree Prognosis Molecular Targeted Therapy DNA Mutational Analysis Transplantation, Heterologous Antineoplastic Combined Chemotherapy Protocols Amino Acid Substitution Immunohistochemistry Neoplasm Transplantation Oligonucleotide Array Sequence Analysis Survival Analysis Survival Rate Models, Molecular Mutagenesis, Site-Directed Tissue Array Analysis Inhibitory Concentration 50 Neoplasm Staging Risk Retrospective Studies Sequence Alignment Flow Cytometry Follow-Up Studies Immunoblotting Genetic Testing Sequence Analysis, DNA Cloning, Molecular Kaplan-Meier Estimate Prospective Studies Registries Gene Knockdown Techniques Risk Assessment Microscopy, Fluorescence Disease-Free Survival Clinical Trials as Topic Tumor Burden Sensitivity and Specificity Disease Models, Animal Combined Modality Therapy

Phenomena and Processes73

Mutation Point Mutation Mutation, Missense Mitosis Phosphorylation MAP Kinase Signaling System Gene Expression Regulation, Neoplastic Apoptosis Cell Proliferation Cell Cycle Germ-Line Mutation Base Sequence Frameshift Mutation Drug Resistance, Neoplasm Chromosome Segregation Signal Transduction Amino Acid Sequence Transfection Protein Binding Cell Survival Cell Division Kinetochores RNA Interference Down-Regulation M Phase Cell Cycle Checkpoints Genetic Predisposition to Disease Dose-Response Relationship, Drug Phenotype Polyploidy Genotype Promoter Regions, Genetic Cytokinesis Alleles Protein Structure, Tertiary Exons Enzyme Activation Binding Sites Gene Expression Heterozygote Drug Synergism Up-Regulation Amino Acid Substitution Gene Expression Regulation, Enzymologic Genes, p53 Transcription, Genetic Cell Cycle Checkpoints DNA Methylation Cell Movement Mutation Rate Genes, Tumor Suppressor Gene Silencing Time Factors Polymorphism, Single-Stranded Conformational Sequence Homology, Amino Acid Anaphase Kinetics Inhibitory Concentration 50 Risk Polymorphism, Genetic Genes, BRCA1 Gene Deletion Chromosomal Instability Ploidies Cell Growth Processes Mutagenesis Cell Physiological Processes G2 Phase Homozygote Sequence Deletion Gene Expression Regulation Centromere Sensitivity and Specificity Substrate Specificity

Disciplines and Occupations1

Immunohistochemistry

Anthropology, Education, Sociology and Social Phenomena1

National Cancer Institute (U.S.)

Information Science5

Molecular Sequence Data Base Sequence Amino Acid Sequence Survival Rate Registries

Named Groups1

Health Care15

Survival Analysis Survival Rate Risk Retrospective Studies National Cancer Institute (U.S.)Follow-Up Studies Genetic Testing Kaplan-Meier Estimate Prospective Studies Registries Risk Assessment Disease-Free Survival Clinical Trials as Topic Age Factors Sensitivity and Specificity

Geographicals1

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Information Science Health Care

Aurora Kinases Aurora Kinase A Aurora Kinase B Aurora Kinase C Protein-Serine-Threonine Kinases Mutation Protein Kinase Inhibitors Point Mutation Mutation, Missense Cell Line, Tumor Neoplasms Phosphatidylinositol 3-Kinases Mitosis Protein Kinases Phosphorylation MAP Kinase Signaling System Gene Expression Regulation, Neoplastic Antineoplastic Agents Early Detection of Cancer Apoptosis Molecular Sequence Data Mice, Nude Spindle Apparatus Breast Neoplasms Ovarian Neoplasms Cell Proliferation Cell Cycle Cell Cycle Proteins Lung Neoplasms Germ-Line Mutation Blotting, Western Base Sequence Neoplasm Proteins Frameshift Mutation Prostatic Neoplasms RNA, Small Interfering Colonic Neoplasms RNA, Messenger Piperazines Drug Resistance, Neoplasm Cell Transformation, Neoplastic Chromosome Segregation Signal Transduction Xenograft Model Antitumor Assays Reverse Transcriptase Polymerase Chain Reaction Amino Acid Sequence Tumor Suppressor Protein p53 HeLa Cells src-Family Kinases Transfection Calcium-Calmodulin-Dependent Protein Kinases Benzamides Protein Binding Tumor Cells, Cultured Stomach Neoplasms Neoplasm Invasiveness Nuclear Proteins Gene Expression Profiling Neoplasm Metastasis Cell Line Polymerase Chain Reaction Cell Survival Cell Division Kinetochores Proto-Oncogene Proteins Organophosphates Drug Screening Assays, Antitumor Azepines RNA Interference Pancreatic Neoplasms Microtubule-Associated Proteins Pyrimidines Enzyme Inhibitors Down-Regulation Models, Biological M Phase Cell Cycle Checkpoints DNA-Binding Proteins Quinazolines Genetic Predisposition to Disease Histones Centrosome Protein Kinase C Pedigree Prognosis Tumor Markers, Biological Dose-Response Relationship, Drug p38 Mitogen-Activated Protein Kinases Phenotype Molecular Targeted Therapy Polyploidy Genotype Cyclic AMP-Dependent Protein Kinases Transcription Factors Mitogen-Activated Protein Kinase 1 DNA, Neoplasm Promoter Regions, Genetic Cytokinesis DNA Mutational Analysis Protein-Tyrosine Kinases Alleles

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