Mutations results tumor suppressor proteins. Medical search. Frequent questions

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Anatomy16

Cell Line, Tumor Cell Line Tumor Cells, Cultured Fibroblasts Cells, Cultured HeLa Cells Cell Nucleus COS Cells HCT116 Cells Cell Line, Transformed Cytoplasm NIH 3T3 Cells HEK293 Cells Epithelial Cells 3T3 Cells Embryo, Mammalian

Organisms12

Mice, Knockout Mice, Inbred C57BL Mice, Transgenic Mice, Nude Drosophila Escherichia coli Saccharomyces cerevisiae Mice, Inbred BALB C Cercopithecus aethiops Drosophila melanogaster Mice, Mutant Strains Papillomaviridae

Diseases26

Cell Transformation, Neoplastic Neoplasms Kidney Neoplasms Breast Neoplasms Wilms Tumor Osteosarcoma Adenocarcinoma Neurofibromatosis 2 Carcinoma, Renal Cell Neoplasms, Experimental von Hippel-Lindau Disease Liver Neoplasms Skin Neoplasms Lung Neoplasms Brain Neoplasms Colonic Neoplasms Retinoblastoma Carcinoma, Squamous Cell Carcinoma, Hepatocellular Disease Progression Disease Models, Animal Neoplasm Metastasis Ovarian Neoplasms Syndrome Glioblastoma Carcinoid Tumor

Chemicals and Drugs84

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Nuclear Proteins DNA-Binding Proteins Transcription Factors Neurofibromin 2 Adenomatous Polyposis Coli Protein Proto-Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p16 Ubiquitin-Protein Ligases PTEN Phosphohydrolase Cell Cycle Proteins RNA, Messenger Cyclin-Dependent Kinase Inhibitor p21 Repressor Proteins Proteins Neoplasm Proteins DNA Primers Carrier Proteins Ligases Cyclins E2F Transcription Factors Recombinant Fusion Proteins Protein-Serine-Threonine Kinases Membrane Proteins Tumor Markers, Biological DNA Recombinant Proteins E2F1 Transcription Factor Suppressor of Cytokine Signaling Proteins DNA, Neoplasm Trans-Activators Transcription Factor DP1 RNA, Small Interfering Oncogene Proteins, Viral WT1 Proteins Papillomavirus E7 Proteins Drosophila Proteins Retinoblastoma-Binding Protein 1 Retinoblastoma-Like Protein p107 Tumor Necrosis Factor-alpha Proteasome Endopeptidase Complex Intracellular Signaling Peptides and Proteins Phosphoproteins Hypoxia-Inducible Factor 1, alpha Subunit Ubiquitin DNA, Complementary Phosphoric Monoester Hydrolases Cyclin-Dependent Kinases Cytoskeletal Proteins Codon, Nonsense Retinoblastoma-Like Protein p130 BRCA1 Protein Antigens, Polyomavirus Transforming Adaptor Proteins, Signal Transducing Apoptosis Regulatory Proteins beta Catenin Neurofibromin 1 Ubiquitins Adenovirus E1A Proteins Mutant Proteins Homeodomain Proteins Protein Isoforms Luciferases Antineoplastic Agents Codon Adenovirus E1B Proteins Cyclin-Dependent Kinase 4 Serine Proto-Oncogene Proteins c-myc RNA, Neoplasm Suppressor Factors, Immunologic Adenovirus E4 Proteins MicroRNAs Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p27 Hypoxia-Inducible Factor 1 Proto-Oncogene Proteins c-bcl-2 Nerve Tissue Proteins Saccharomyces cerevisiae Proteins

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Transfection Polymerase Chain Reaction Blotting, Western DNA Mutational Analysis Pedigree Reverse Transcriptase Polymerase Chain Reaction Amino Acid Substitution Mutagenesis, Site-Directed Immunohistochemistry Models, Biological Chromosome Mapping Cloning, Molecular Tumor Burden Models, Molecular Sequence Alignment Precipitin Tests Immunoblotting Neoplasms, Experimental Immunoprecipitation Sequence Analysis, DNA Transplantation, Heterologous Two-Hybrid System Techniques Gene Expression Profiling Models, Genetic Disease Models, Animal Microscopy, Fluorescence Flow Cytometry Blotting, Northern Genetic Complementation Test Neoplasm Transplantation Chromatin Immunoprecipitation Oligonucleotide Array Sequence Analysis

Phenomena and Processes86

Genes, Tumor Suppressor Mutation Point Mutation Mutation, Missense Base Sequence Amino Acid Sequence Genes, p53 Protein Binding Transfection Apoptosis Genes, Suppressor Gene Expression Regulation, Neoplastic Signal Transduction Promoter Regions, Genetic Cell Cycle Frameshift Mutation Protein Structure, Tertiary Transcription, Genetic Suppression, Genetic Phosphorylation Cell Proliferation Phenotype Binding Sites Cell Division Alleles Gene Deletion Exons DNA Damage Germ-Line Mutation Transcriptional Activation Heterozygote Down-Regulation Gene Expression Regulation Gene Silencing Amino Acid Substitution Loss of Heterozygosity Sequence Homology, Amino Acid DNA Methylation Sequence Deletion RNA Interference Homozygote Mutagenesis Plasmids Gene Expression Polymorphism, Single-Stranded Conformational Genes, Dominant G1 Phase Cell Aging Genotype Genes, Retinoblastoma Ultraviolet Rays Genes, Neurofibromatosis 2 Codon, Nonsense Cell Survival Oncogenes Time Factors Genes, APC Genes, Recessive Genes, Reporter Protein Transport DNA Repair Ubiquitination Protein Conformation Cell Differentiation Genes, p16 Up-Regulation Codon Amino Acid Motifs Alternative Splicing Cell Movement Enzyme Activation Protein Processing, Post-Translational Protein Stability Kinetics Mutation Rate S Phase Genes, ras Genes, Wilms Tumor Acetylation Microsatellite Repeats Gamma Rays Conserved Sequence Structure-Activity Relationship Genetic Vectors Active Transport, Cell Nucleus Genes, Lethal

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Mutation Von Hippel-Lindau Tumor Suppressor Protein Point Mutation Mutation, Missense Tumor Suppressor Protein p14ARF Retinoblastoma Protein Molecular Sequence Data Cell Line, Tumor Proto-Oncogene Proteins c-mdm2 Base Sequence Amino Acid Sequence Nuclear Proteins Genes, p53 Protein Binding DNA-Binding Proteins Cell Line Transcription Factors Transfection Apoptosis Genes, Suppressor Gene Expression Regulation, Neoplastic Neurofibromin 2 Adenomatous Polyposis Coli Protein Proto-Oncogene Proteins Signal Transduction Promoter Regions, Genetic Cell Cycle Frameshift Mutation Tumor Cells, Cultured Protein Structure, Tertiary Cyclin-Dependent Kinase Inhibitor p16 Ubiquitin-Protein Ligases PTEN Phosphohydrolase Transcription, Genetic Suppression, Genetic Cell Cycle Proteins RNA, Messenger Cell Transformation, Neoplastic Phosphorylation Cell Proliferation Cyclin-Dependent Kinase Inhibitor p21 Phenotype Binding Sites Repressor Proteins Proteins Cell Division Polymerase Chain Reaction Neoplasm Proteins Blotting, Western DNA Primers Alleles Neoplasms Gene Deletion Exons Carrier Proteins Ligases DNA Damage DNA Mutational Analysis Germ-Line Mutation Cyclins Transcriptional Activation E2F Transcription Factors Heterozygote Pedigree Down-Regulation Fibroblasts Cells, Cultured Recombinant Fusion Proteins Protein-Serine-Threonine Kinases Membrane Proteins Reverse Transcriptase Polymerase Chain Reaction Tumor Markers, Biological HeLa Cells Gene Expression Regulation DNA Gene Silencing Amino Acid Substitution Mutagenesis, Site-Directed Loss of Heterozygosity Sequence Homology, Amino Acid Cell Nucleus Recombinant Proteins DNA Methylation E2F1 Transcription Factor Sequence Deletion Suppressor of Cytokine Signaling Proteins Immunohistochemistry RNA Interference DNA, Neoplasm Trans-Activators Kidney Neoplasms Homozygote Mutagenesis Transcription Factor DP1 Models, Biological RNA, Small Interfering Oncogene Proteins, Viral

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