Von Hippel-Lindau Tumor Suppressor Proteinvon Hippel-Lindau DiseasePancreatic CystKidney NeoplasmsHypoxia-Inducible Factor 1, alpha SubunitCarcinoma, Renal CellProcollagen-Proline DioxygenaseTumor Suppressor Protein p53Nobel PrizeUbiquitin-Protein LigasesTumor Suppressor ProteinsGenes, Tumor SuppressorHemangioblastomaRho FactorMutationTumor Suppressor Protein p14ARFPoint MutationRetinoblastoma ProteinCell Line, TumorMutation, MissenseProto-Oncogene Proteins c-mdm2Molecular Sequence Datavon Willebrand FactorGenes, p53Nuclear ProteinsProtein BindingBase SequenceDNA-Binding ProteinsCell LineTranscription FactorsGene Expression Regulation, NeoplasticTransfectionApoptosisAmino Acid SequenceNeurofibromin 2Adenomatous Polyposis Coli ProteinGenes, SuppressorCell CycleProto-Oncogene ProteinsPromoter Regions, GeneticTumor Cells, CulturedCyclin-Dependent Kinase Inhibitor p16Signal TransductionPTEN PhosphohydrolaseCell Cycle ProteinsCell Transformation, NeoplasticProtein Structure, TertiaryCyclin-Dependent Kinase Inhibitor p21Transcription, GeneticCell ProliferationPhosphorylationLigasesNeoplasm ProteinsRNA, MessengerNeoplasmsRepressor ProteinsCell DivisionProteinsBinding SitesDNA DamageBlotting, WesternSuppression, GeneticCyclinsTranscriptional ActivationFrameshift Mutationvon Willebrand DiseasesE2F Transcription FactorsDown-RegulationPolymerase Chain ReactionCarrier ProteinsGene DeletionTumor Markers, BiologicalGerm-Line MutationDNA PrimersGene SilencingRecombinant Fusion ProteinsProtein-Serine-Threonine KinasesLoss of HeterozygosityReverse Transcriptase Polymerase Chain ReactionCells, CulturedGene Expression RegulationHeLa CellsFibroblastsDNA MethylationE2F1 Transcription FactorCell HypoxiaMembrane ProteinsSuppressor of Cytokine Signaling ProteinsRNA InterferenceExonsDNA, NeoplasmTrans-ActivatorsCell NucleusDNARNA, Small InterferingTranscription Factor DP1AllelesOncogene Proteins, ViralWT1 ProteinsPhenotype