• symptoms
  • The International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) is a coding of diseases and signs, symptoms, abnormal findings, complaints, social circumstances and external causes of injury or diseases, as classified by the World Health Organization (WHO). (wikipedia.org)
  • In all cases of cryofibrinogenemic disease, however, patients should avoid the exposure of afflicted body parts to cold weather or other environmental triggers of symptoms and avoid using cigarettes or other tobacco products. (wikipedia.org)
  • These surveys are patient-reported outcome measures, may be questionnaires or surveys, and may be used to evaluate patient satisfaction, symptoms, disease state, or psychological well-being. (wikipedia.org)
  • disorders
  • Our research in Musculoskeletal Diseases (MSD) focuses on discovering innovative therapies for muscle wasting and bone disorders. (novartis.com)
  • 3) The blood of individuals, particularly those with cryofibriognemic disease associated with other severe disorders, has high levels of immunological elements such as immunoglobulins or immune complexes that interact with fibronectin to promote blood clotting. (wikipedia.org)
  • The diagnosis of secondary cryofibrinogenemia also requires evidence for the cited infectious, malignant, premalignant vasculitis, and autoimmune disorders while the diagnosis of primary cryofibriongenemia requires a lack of evidence for 1) the cited associated disorders, 2) other vascular occlusive diseases, and 3) cryoglobulinemia. (wikipedia.org)
  • Diabetes
  • October 1976-The Arthritis, Diabetes, and Digestive Diseases Amendments of 1976 (P.L. 94-562) established the National Arthritis Advisory Board to review and evaluate the implementation of the Arthritis Plan, prepared in response to the National Arthritis Act (P.L. 93-640). (wikipedia.org)
  • The SGC target proteins have relevance to human health and disease, such as diabetes, cancer and infectious diseases such as malaria. (wikipedia.org)
  • clinical
  • To acquire skill in diagnosing and monitoring the disease course of PsA, a clinician must recognize that there are multiple clinical domains that may be affected, including peripheral joints, entheseal insertion sites, dactylitis, and the spine. (jrheum.org)
  • paracetamol is sometimes combined with an NSAID (in place of an opioid) in clinical practice to enhance the pain relief of the NSAID while still receiving the injury/disease modulating effect of NSAID-induced inflammation reduction (which is not received from opioid/paracetamol combinations). (wikipedia.org)
  • Study
  • January 1975-The National Arthritis Act (P.L. 93-640) established the National Commission on Arthritis and Related Musculoskeletal Diseases to study the problem of arthritis and to develop an arthritis plan. (wikipedia.org)
  • Novel Approaches for Targeting Kinases Allosteric Inhibition, Allosteric Activation and Pseudokinases": Deregulation of protein kinases are very involved with a plethora of different diseases, and the study involved the finding of kinase inhibitors that have good pharmacokinetic/pharmacodynamic properties. (wikipedia.org)
  • abnormal
  • This separates cryofibrinogenemia from two pathological blood-clotting/bleeding diseases that can mimic cryofibrinogenemia but are due to structurally abnormal fibrinogen viz. (wikipedia.org)
  • treatment
  • The patient receives an invitation to the planned surgery usually in the treatment of spinal or joint diseases. (pshp.fi)
  • In order to prepare for the new facilities, the Musculoskeletal Disease Surgery Outpatient Clinic, TULES, has been developing and preparing for the change systematically for several years, aiming to provide effective, cost-efficient and quality treatment. (pshp.fi)
  • Also, they are "doubly disadvantaged" by the higher attributable risk from risk taking behavior (e.g., smoking, substance use) in the context of the underlying chronic disease or its treatment. (bmj.com)
  • Caution is recommended as it only shows a general relation with physiological markers of the disease and the variation is such that it has limited applicability in individual assessments, including treatment decisions. (wikipedia.org)
  • Although originally designed as a chemotherapy drug (using high doses), in low doses, methotrexate is a generally safe and well tolerated drug in the treatment of certain autoimmune diseases. (wikipedia.org)
  • Not everyone with rheumatoid arthritis responds favorably to treatment with methotrexate, but multiple studies and reviews showed that the majority of people receiving methotrexate for up to one year had less pain, functioned better, had fewer swollen and tender joints, and had less disease activity overall as reported by themselves and their doctors. (wikipedia.org)
  • Although they are not used for analgesic benefits they are widely utilized in the treatment of diseases related to inflammation of the lungs such as asthma and COPD as well as sinus inflammation in allergic rhinitis. (wikipedia.org)
  • this process can go too far, however, leading to graft vs host disease, the most serious side effect of this treatment. (wikipedia.org)
  • The FDA has approved five hematopoietic stem-cell products derived from umbilical cord blood, for the treatment of blood and immunological diseases. (wikipedia.org)
  • Sarcoidosis
  • In 2015 pulmonary sarcoidosis and interstitial lung disease affected 1.9 million people globally and they resulted in 122,000 deaths. (wikipedia.org)
  • Sarcoidosis was first described in 1877 by the English doctor Jonathan Hutchinson as a non-painful skin disease. (wikipedia.org)
  • involvement
  • There are four stages of pulmonary involvement based on radiological stage of the disease, which is helpful in prognosis: Stage I: bilateral hilar lymphadenopathy (BHL) alone Stage II: BHL with pulmonary infiltrates Stage III: pulmonary infiltrates without BHL Stage IV: fibrosis. (wikipedia.org)
  • treat
  • It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. (wikipedia.org)
  • Next, when human cells are transformed by BRAF or resistant to its inhibition, copper chelators used to treat Wilson's disease can help lessen tumor growth. (wikipedia.org)
  • Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. (wikipedia.org)
  • children
  • Quality of life assessments in children and adolescents that allows better measure of the personal impact of pediatric musculoskeletal disease is lacking. (boneandjointburden.org)
  • Another stem-cell therapy called Prochymal, was conditionally approved in Canada in 2012 for the management of acute graft-vs-host disease in children who are unresponsive to steroids. (wikipedia.org)
  • variation
  • Although a single factor is not generally sufficient to cause the disease, about half of the variation in susceptibility has been assigned to genetic factors. (wikipedia.org)
  • wrist
  • 727.03) Trigger finger, acquired (727.04) de Quervain's disease (727.05) Tenosynovitis, hand/wrist (727.06) Tenosynovitis, foot/ankle (727.1) Bunion (727.4) Ganglion and cyst of synovium, tendon, and bursa (727.42) Ganglion, tendon sheath (727.43) Ganglion, unspec. (wikipedia.org)
  • shown
  • A number of studies have shown that there is a greater prevalence of the disease among siblings and especially identical twins, indicating a hereditary basis. (wikipedia.org)