• gene
  • Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene. (wikipedia.org)
  • Some metabolic diseases affect the normal metabolic processes in the body: Acid maltase deficiency Carnitine deficiency Carnitine palmitoyltransferase II deficiency Debrancher Enzyme Deficiency Lactate dehydrogenase deficiency Mitochondrial myopathy Myoadenylate deaminase deficiency Glycogen storage disease type V Phosphofructokinase deficiency Phosphoglycerate kinase deficiency The MSTN gene also plays a big role in muscle development. (wikipedia.org)
  • Mef2 is a critical regulator in heart development and cardiac gene expression. (wikipedia.org)
  • Mef2c, the first gene to be expressed in the heart, is necessary for the development of the anterior (secondary) heart field (AHF), which helps to form components of the cardiac outflow tract and most of the right ventricle. (wikipedia.org)
  • clarification needed] The Belgian Blue has a natural mutation in the myostatin gene which codes for the protein, myostatin ("myo" meaning muscle and "statin" meaning stop). (wikipedia.org)
  • The truncated myostatin gene is unable to function in its normal capacity, resulting in accelerated lean muscle growth. (wikipedia.org)
  • Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene. (wikipedia.org)
  • body
  • Whatever your reason for wanting a fat-free body stacked with muscle, there is information you need to help you reach your goals for building muscle. (herculesgyminfo.com)
  • When you think of building muscle, understand that this does not necessarily translate to becoming a body builder. (herculesgyminfo.com)
  • You can injure your muscles if you do not keep your body well hydrated. (herculesgyminfo.com)
  • Your body requires a variety of vitamins, minerals, and micronutrients to build new muscle after you work out. (herculesgyminfo.com)
  • Message Body (Your Name) thought you would like to see the Development web site. (biologists.org)
  • Pax7 expressing muscle stem cells accompany all skeletal muscles in the body and in healthy individuals, efficiently repair muscle after injury. (frontiersin.org)
  • It is often overlooked that muscular dystrophies affect head and body skeletal muscle differently. (frontiersin.org)
  • Along with adding muscle, these exercises help you improve your strength and condition your body. (herculesgyminfo.com)
  • not in citation given] Difficulty building muscle is often associated with the ectomorph body somatotype, however other common reasons also include a lack of proper nutrition, suitable physical activity level or not allowing enough recovery time for the stressed muscles to regain their previous state and then grow bigger (overtraining). (wikipedia.org)
  • Those are typically either diseases that affect muscles and/or protein synthesis, or there might be a genetic disorder that hinders protein synthesis and/or limits the maximum amount of muscles the body can hold to a relatively small amount for that person. (wikipedia.org)
  • Muscle Control, or Body Development by Will-Power. (wikipedia.org)
  • Female body shape or female figure is the cumulative product of a woman's skeletal structure and the quantity and distribution of muscle and fat on the body. (wikipedia.org)
  • At puberty, a girl's sex hormones, mainly estrogen, will promote breast development and a wider pelvis tilted forward for child bearing, and until menopause a woman's estrogen levels will cause her body to store excess fat in the buttocks, hips and thighs, but generally not around her waist, which will remain about the same size as it was before puberty. (wikipedia.org)
  • Head should be narrow with a white halter mark Flat poll with no wool and head covered in fine hair with white tips on the ears Medium sized sheep with a well muscled body Fleece must be dense They should stand square and balanced Ideal color is a darker head and shoulder, light blue color on the back, and dark again around their back end. (wikipedia.org)
  • The cremaster muscle is a paired structure, there being one on each side of the body. (wikipedia.org)
  • Zebrafish
  • Here, we report the generation and phenotypic analysis of murcb mutant zebrafish, which display impaired swimming capacity, skeletal muscle fibrosis and T-tubule abnormalities during development. (pubmedcentralcanada.ca)
  • To address these questions, we generated a Cavin4b/Murcb deficient zebrafish line by targeted TALEN mutagenesis and found that Cavin4b/Murcb is necessary for the formation and function of skeletal muscle. (pubmedcentralcanada.ca)
  • Cavin4b/Murcb mutant zebrafish exhibit progressive skeletal muscle deterioration, disrupted membrane structures early in development and aberrant growth factor signaling. (pubmedcentralcanada.ca)
  • To shed light on this, we traced the emergence of head muscle stem cells in the key vertebrate models for myogenesis, chicken, mouse, frog and zebrafish, using Pax7 as key marker. (frontiersin.org)
  • lean muscle
  • Both of these breeds have an increased ability to convert feed into lean muscle, which causes these particular breeds' meat to have a reduced fat content and reduced tenderness. (wikipedia.org)
  • commitment
  • Due to the fact that gaining muscle is a commitment that is long-term and requires a significant amount of time, maintaining motivation is vitally important. (herculesgyminfo.com)
  • diseases
  • In humans, a heterogeneous group of genetic diseases, termed muscular dystrophies (MD), lead to skeletal muscle dysfunction. (pubmedcentralcanada.ca)
  • Muscular dystrophies (MD) are a heterogeneous group of genetic diseases that result in progressive dysfunction of skeletal muscle [ 1 ]. (pubmedcentralcanada.ca)
  • Currently, the in vitro manipulation and culture of these cells is still in its infancy, yet muscle stem cells may be the most promising route toward the therapy of muscle diseases such as muscular dystrophies. (frontiersin.org)
  • However, in a number of diseases including muscular dystrophies, cancer and HIV/Aids, the ability of muscle stem cells to repair muscle is compromised. (frontiersin.org)
  • Muscular
  • These data link Murc with developmental defects in T-tubule formation and progressive muscle dysfunction, thereby providing a new candidate for the etiology of muscular dystrophy. (pubmedcentralcanada.ca)
  • Membrane structures are critical to skeletal muscle excitation-contraction coupling, and disruptions in key membrane proteins can lead to muscular dystrophy. (pubmedcentralcanada.ca)
  • Caveolae, micro-domains in the cell membrane, are known to be important in forming muscle-specific membrane structures such as the T-tubule network and play a role in some forms of muscular dystrophy. (pubmedcentralcanada.ca)
  • However, it is poorly understood how Cavins function in skeletal muscle development or whether Cavin dysfunction can lead to muscular dystrophy. (pubmedcentralcanada.ca)
  • Therefore, it is often overlooked that muscular dystrophies differentially target muscle groups in the head and in the trunk (reviewed in Emery, 2002 ). (frontiersin.org)
  • mesoderm
  • We propose that this unique mechanism of muscle stem cell development is a legacy of the evolutionary history of the chordate head mesoderm. (frontiersin.org)
  • The function of MyoD in development is to commit mesoderm cells to a skeletal myoblast lineage, and then to regulate that continued state. (wikipedia.org)
  • Mef2
  • Here, we have identified a novel heart- and muscle-specific microRNA, miR-92b, which is activated by Mef2 and subsequently downregulates Mef2 through binding to its 3′UTR, forming a negative regulatory circuit that fine-tunes the level of Mef2. (biologists.org)
  • Deletion of miR-92b caused abnormally high Mef2 expression, leading to muscle defects and lethality. (biologists.org)
  • Blocking miR-92b function using microRNA sponge techniques also increased Mef2 levels and caused muscle defects similar to those seen with the miR-92b deletion. (biologists.org)
  • Additionally, overexpression of miR-92b reduced Mef2 levels and caused muscle defects similar to those seen in Mef2 RNAi, and Mef2 overexpression led to reversal of these defects. (biologists.org)
  • bone
  • The Belgian Blue's bone structure is the same as normal cattle, albeit holding a greater amount of muscle, which causes them to have a greater meat to bone ratio. (wikipedia.org)
  • Adult
  • The cremaster muscle occasionally experiences painful spasms or cramps in adult males which can be chronic and debilitating. (wikipedia.org)
  • groups
  • Different groups of muscles are affected depending on the type of MD and complications can include confinement to a wheelchair, scoliosis, difficulty swallowing, impaired breathing, cardiomyopathies, and early death [ 2 , 3 ]. (pubmedcentralcanada.ca)
  • Building these muscle groups will also make your waist appear smaller. (herculesgyminfo.com)
  • This coincides with the observation that without RYR1 present, muscle cells appear in smaller groups, are underdeveloped, and lack organization. (wikipedia.org)
  • citation
  • citation needed] Double-muscled cows can experience dystocia (a difficult birth), even when bred to normal beef bulls or dairy bulls, because of a narrower birth canal. (wikipedia.org)
  • citation needed] Testosterone is a steroid hormone which helps build and maintain muscles with physical activity, such as exercise. (wikipedia.org)