• Effects
  • We investigated the effects of corticosterone (10 −6 to 10 −12 mol/L) on early vascular mineralocorticoid receptor signaling by Western blotting, confocal microscopy, and myography. (ahajournals.org)
  • All effects of the catecholamines adrenaline, noradrenaline, dopamine and isoprenaline could be accounted for by an action as agonists, activating substances, on α- und β-adrenoceptors co-existing in vascular smooth muscle. (wikipedia.org)
  • Effects of visnadine on rat isolated vascular smooth muscles. (wikipedia.org)
  • involves
  • She has other research that involves basic cellular interactions in the artery wall, and the definition of single transduction pathways through which factors act to enhance vascular disease regression and prevent disease development/progression. (wikipedia.org)
  • pathways
  • These new mineralocorticoid receptor-dependent signaling pathways suggest that glucocorticoids may contribute to vascular disease via mineralocorticoid receptor signaling, independent of circulating aldosterone. (ahajournals.org)
  • acute
  • Hydrogen sulfide (H2S) deficiency can be detrimental to the vascular function after an acute myocardial infarction (AMI). (wikipedia.org)
  • disease
  • G. Orasanu and J. Plutzky, "The pathologic continuum of diabetic vascular disease," Journal of the American College of Cardiology , vol. 53, no. 5, pp. (hindawi.com)
  • P. J. Aschner and A. J. Ruiz, "Metabolic memory for vascular disease in diabetes," Diabetes Technology and Therapeutics , vol. 14, no. 1, pp. (hindawi.com)
  • Although there is evidence for a two-hit mechanism (germline and somatic inactivation of two PKD alleles) explaining the focal development of renal and hepatic cysts, haploinsufficiency is more likely to account for the vascular manifestations of the disease. (wikipedia.org)
  • mechanism
  • Vascular smooth muscle contracts or relaxes to change both the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). (wikipedia.org)