Muscle creatinine. Medical search. Frequent questions

This article discusses the test done to measure the amount of creatinine in your urine.A blood test can also be used to determine your creatinine level. (answers.com)
The creatinine urine test measures the amount of creatinine in urine. (ucsfhealth.org)
This test measures the amount of albumin and compares it to the amount of creatinine (a waste product that comes from the normal wear and tear of muscles in the body) in your urine. (cdc.gov)
A serum creatinine blood test measures the amount of creatinine in your blood. (cdc.gov)
Creatinine occurs naturally in the body and based on the amount of creatinine - the laboratory determines the dilution of urine. (fotolog.com)

BACKGROUND: Muscle mass, as determined from 24-h urinary creatinine excretion rate (CER), is an independent predictor for mortality and graft failure in renal transplant recipients (RTR). (rug.nl)
All 24-hour urine collections should be assessed for accuracy/completeness by calculating the 24-hour total creatinine excretion. (medscape.com)
Since the ACR depends not only on urinary albumin but also on urinary creatinine excretion, it will be affected by gender and age because muscle mass is lower in females than in males and decreases with age. (cdc.gov)

Creatinine is critically important in assessing renal function because it has several interesting properties. (medscape.com)
As a result, one should look at the calculated eGFR (estimated glomerular filtration rate), as reported from the measured serum creatinine, to assess renal function. (medscape.com)
When CPK is 10 times normal, rhabdomyolysis is possible, and urgent attention, including evaluation of renal function, rapid hydration, and possible hospitalization, may be required.2 Interestingly, however, Dr. Eckel says some patients have CPK elevations without muscle symptoms. (medpagetoday.com)
A more accurate real-time description of renal function in AKI is needed, and some published data suggest that equations based on serum creatinine that estimate glomerular filtration rate (eGFR) can provide this. (hindawi.com)
Some published data, albeit in abstract form, suggest that MDRD eGFR calculations may be more useful than serum creatinine alone in estimating renal function in critically ill patients when compared to CrCl measurements [ 14 , 15 ]. (hindawi.com)

As a result, for adult patients (age 18 and over), along with every measured serum creatinine, most clinical labs now report an estimated GFR (eGFR). (medscape.com)
[ 3 , 10 ] The eGFR accounts for some of these variables, and it can alert physicians to significant reductions in GFR even when the serum creatinine appears to be normal or only minimally elevated. (medscape.com)
For example, a white woman with a serum creatinine of 1.0 (a value within the traditional reference interval) has an eGFR of 59 mL/min/1.73 m 2 , a value consistent with chronic kidney disease . (medscape.com)
CMI was defined as creatinine filtration (the product of serum creatinine times eGFR on the basis of cystatin C ) and was analyzed in sex -specific tertiles. (bvsalud.org)
This study tests whether creatinine or cystatin-C-based eGFR equations, used in patients with CKD, offer an accurate representation of 4-hour creatinine clearance (4CrCl) in critically ill patients with AKI. (hindawi.com)
eGFR equations were better than creatinine alone at predicting 4CrCl. (hindawi.com)
Previously, the equations for eGFR had a race adjustment that meant Black patients had a higher eGFR despite having the same creatinine level. (scienceblog.com)
The researchers looked at two new eGFR formulas that do not include a race adjustment: one used creatinine alone - the standard test - and the second looked at both creatinine and cystatin, a newer blood test that is thought to improve accuracy when kidney function is at higher ranges. (scienceblog.com)
Using the eGFR creatinine formula, they found that among 350 Black patients, kidney failure was reached at an average 23 months, versus an average 22 months for 122 white patients, which the researchers describe as not having a statistically significant difference. (scienceblog.com)
When they looked at the eGFR creatinine-cystatin formula, they found that among 289 Black patients, kidney failure was reached at an average 21 months, versus an average 26 months for 152 white patients, which was also not statistically significantly different, but more divergent than the results of the eGFR creatinine formula. (scienceblog.com)
So, your healthcare provider will likely compare your BUN level to your creatinine and eGFR levels when evaluating your kidney health. (kidney.org)

Skeletal muscle tissue (SKM) may be damaged due to mechanical, metabolic, and exertional causes. (degruyter.com)
Creatinine, a metabolite of creatine phosphate, an energy store found in skeletal muscle, is produced at a constant rate from skeletal muscle. (nottingham.ac.uk)
Urinary and plasma creatinine have been used in clinical practice as indicators of skeletal muscle mass in health and disease. (nottingham.ac.uk)
Our study aimed to test the hypothesis that plasma myoglobin and creatinine concentration could accurately predict skeletal muscle mass and aerobic capacity in colorectal cancer (CRC) patients and matched healthy controls and thereby an indicative of aerobic performance. (nottingham.ac.uk)
Skeletal muscle tetany occurs at 16-20 mA. (medscape.com)
AST is present in mitochondrial and cytosolic enzymes (80% and 20% of activity respectively), found in brain, cardiac muscle, kidneys, leucocytes, liver, lungs, red blood cells and skeletal muscle 2 . (randox.com)
Malignant hyperthermia (MH) is a rare, inherited disorder of skeletal muscle that presents as a hypermetabolic response triggered by halogenated anesthetics, succinylcholine, or both. (medscape.com)
MH is an inherited disorder of skeletal muscle that classically presents itself as a hypermetabolic response to halogenated anesthetic agents, succinylcholine, or both. (medscape.com)
The direct cause of MH when it is triggered is uncontrolled release of intracellular calcium from the skeletal muscle sarcoplasmic reticulum. (medscape.com)
Skeletal muscle is damamged. (professionalmuscle.com)
[ 4-6 ] Although the mechanisms are poorly understood, statins have been shown to reduce muscle mitochondrial oxidative capacity and content in humans [ 7-10 ] and impair exercise-mediated mitochondrial adaptations in skeletal muscle. (medscape.com)
For example, the Effect of Statins on Skeletal Muscle Function and Performance (STOMP) trial is, to our knowledge, the only randomized, double-blind clinical trial that has examined aerobic exercise performance and muscle strength before and after treatmentwith placebo or high-dose atorvastatin. (medscape.com)

Urea and creatinine are nitrogenous end products of metabolism. (wikipedia.org)
Creatinine is a break down product of muscle metabolism and is measured in the blood. (kidney.org)
As a blood test, it is an important indicator of the health of the kidneys because it is an easily measured by-product of muscle metabolism that is excreted unchanged by the kidneys. (aidsmap.com)

Serum and urine creatinine, as well as creatinine clearance, are used to assess kidney function. (uniprix.com)
If kidney function is not normal, creatinine level in your urine decreases. (ucsfhealth.org)
The creatinine clearance test , which involves a 24-hour urine collection, can also provide an estimate of kidney function. (ucsfhealth.org)
Lower creatinine levels generally mean that the kidneys are removing creatinine faster from the blood, which signals better kidney function. (harvard.edu)
This led scientists to reason that creatinine levels may be naturally higher in Black individuals without compromised kidney function. (harvard.edu)

Low muscle mass, liver disease or muscle conditions may explain low serum creatinine levels. (uniprix.com)
Additionally, WWBV+DHEA supplementation improved exercise performance, testosterone levels and glycogen contents of both liver and muscle. (medsci.org)
Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. (loinc.org)
Although diagnosing liver cirrhosis with serum creatinine has many shortcomings, a dynamic change in this marker is still the main diagnostic criterion for AKI. (hindawi.com)
The relationship reverse T3 (RT3) hormone and T4 in tissues between creatinine or BUN and thyroid such as liver, kidneys and muscles [ 8,9 ]. (who.int)

Creatinine is a chemical byproduct of muscle activity. (testing.com)

In medicine, the urea-to-creatinine ratio (UCR), known in the United States as BUN-to-creatinine ratio, is the ratio of the blood levels of urea (BUN) (mmol/L) and creatinine (Cr) (μmol/L). BUN only reflects the nitrogen content of urea (MW 28) and urea measurement reflects the whole of the molecule (MW 60), urea is just over twice BUN (60/28 = 2.14). (wikipedia.org)
Urine creatinine (24-hour urine collection) values can range from 500 to 2000 mg/day (4,420 to 17,680 mmol/day). (ucsfhealth.org)

A new marker of GFR, cystatin C, introduced in 1979, has been shown to be virtually uninfluenced by muscle mass. (lu.se)
In this editorial, the simultaneous use of creatinine and cystatin C to estimate GFR, muscle mass and selective glomerular hypofiltration syndromes is described. (lu.se)
This paper describes a novel creatinine muscle index (CMI) on the basis of serum creatinine and cystatin C . CMI was moderately associated with frailty among older adults . (bvsalud.org)
This study describes a novel creatinine muscle index (CMI) on the basis of serum creatinine and cystatin C in a community -based sample of older adults from the Atherosclerosis Risk in Communities Study. (bvsalud.org)
These findings suggest that the new creatinine-cystatin equation, but not the creatine equation, is still associated with differences in pre-emptive wait time by race," said Ku. (scienceblog.com)

Creatinine filtration may be an index of muscle mass and have utility in clinical practice, particularly at low levels. (bvsalud.org)
Serum creatinine levels vary in children. (uniprix.com)
In addition to creatinine measurements, blood urea nitrogen levels are also measured. (uniprix.com)
Serum creatinine levels are fairly constant and proportional to muscle mass. (uniprix.com)
Pregnancy and significant muscle loss (amputation, paralysis, etc.) are usually associated with decreased serum creatinine levels. (uniprix.com)
Improper urine collection can affect creatinine clearance or urine creatinine levels. (uniprix.com)
Age is also associated with lower urine creatinine levels. (uniprix.com)
Normal levels for you will depend on your sex, age, and the amount of muscle mass your body has. (cdc.gov)
Evaluate the degree of muscle pain, weakness, or cramping along with creatinine phosphokinase (CPK) levels. (medpagetoday.com)
High sugar levels can also affect other organs like muscles, nerves, eyes, heart, blood vessels as well as Kidneys . (medindia.net)
Blood is tested to detect creatinine levels. (medindia.net)
Fenofibrate reversibly increases serum creatinine levels. (nih.gov)
What are BUN & creatinine levels? (kidney.org)
Since measured drug levels can fluctuate with the level of creatinine, a key aspect of your laboratory testing is creatinine adjustment. (dominiondiagnostics.com)
With creatinine adjusted drug levels, you can better monitor drug usage and redefine program goals to increase treatment eff ectiveness. (dominiondiagnostics.com)
Low levels of creatinine in the urine may point to a kidney disease or another condition affecting the kidneys or urinary tract. (kidshealth.org)
The problem with creatinine is folks with larger muscle mass, or who train hard can have seemingly elevated creatinine levels, which can make GFR appear to be low. (robbwolf.com)
The formula is based on measuring the blood levels of creatinine, a waste product removed by the kidneys, and then plugging in variables, including a person's age, sex and race (Black versus White/Other). (harvard.edu)
Then, in the 1990s, researchers noticed that Black individuals had faster kidney filtration rates, even at the same creatinine levels as white individuals of the same age and sex. (harvard.edu)
Why Black people have comparatively higher creatinine levels is not well understood. (harvard.edu)
A popular misconception posits that higher creatinine levels are due to higher muscle mass among Black individuals since muscle releases more creatinine. (harvard.edu)
The rationale for this is based on earlier studies that show Black people may have naturally higher levels of creatinine. (scienceblog.com)
When kidneys become inefficient or overloaded, creatinine levels rise. (juicing-for-health.com)
It is characterized by pain, stiffness, loss of strength and limited range of motion with elevated levels of creatinine kinase in the blood which is an enzyme found in muscle that is released when it breaks down. (selfgrowth.com)
High creatinine levels can be a sign of acute kidney injury and/or chronic kidney disease . (kidney.org)
[ 12 ] STOMP researchers found that more patients in the atorvastatin group than in the placebo group developed muscle complaints, but there were no differences in muscle strength and endurance, aerobic performance, or physical activity levels after 6 months of treatment. (medscape.com)
Blood samples were taken before and after haemodialysis to measure blood urea nitrogen and serum creatinine, triiodothyronine (T3) and thyroxine (T4) levels. (who.int)
We suggest that a feedback relationship exists between the major end catabolic products (creatinine and blood urea nitrogen) and thyroid hormone serum levels. (who.int)
Standard methods were used to measure al hormones and increased serum levels of serum levels of creatinine, BUN, T3 and T4 growth hormone and prolactin [ 5-8 ]. (who.int)
they do not account for persistence of albuminuria or levels of creatinine that are higher than normal as indicated by the Kidney Disease Improving Global Outcomes recommendations. (cdc.gov)
The blood test checks for the level of levels in people with diabetes or in people at risk of developing creatinine, a waste product produced by muscles, to see how type 2 diabetes. (cdc.gov)

Creatinine is removed from the body entirely by the kidneys. (answers.com)

however, urea reabsorbed by the renal tubules can be regulated (increased or decreased) whereas creatinine reabsorption remains the same (minimal reabsorption). (wikipedia.org)
It IS possible to induce kidney failure via extremely damaging exercise, (this has occured in research studies), because the kidney must filter the proteolytic outpouring from the damaged muscle: myoglobin, enzymes, urea from AA oxidation, etc. (professionalmuscle.com)

Urine protein/creatinine ratios and urine albumin/creatinine ratios have proved exceedingly helpful in the evaluation of proteinuria. (medscape.com)
Note: See Analytical Note on comparing the urine albumin-creatinine ratio of the random urine (first collection) and the follow-up first-morning void urine (second collection). (cdc.gov)
Urinary albumin and urinary creatinine are measured in a random urine collected in the MEC (first collection) and a first morning void urine collected by the participant at home (second collection). (cdc.gov)
Urine albumin-creatinine ratio is used to classify stages of chronic kidney disease. (cdc.gov)
Therefore, measurement of urinary albumin and creatinine concentrations are performed and an albumin:creatinine ratio (ACR) was determined from both a random urine and a first morning void. (cdc.gov)
The ratio of urine albumin to urine creatinine is used to predict nephropathy risk in diabetic patients. (cdc.gov)
Urine albumin-to-creatinine ratio (UACR). (cdc.gov)
The urine albumin-creatinine ratio (uACR) test measures the amount of two different substances in your urine - albumin (protein) and creatinine. (kidney.org)
Healthy kidneys keep the albumin in your blood while filtering the creatinine out into the urine. (kidney.org)
The uACR is calculated by dividing the amount of urine albumin by the amount of urine creatinine to find the ratio. (kidney.org)

Creatinine is produced by creatine and creatine phosphate as a result of muscle metabolic processes. (cdc.gov)
Breakdown product of creatine phosphate in muscle, usually produced at a fairly constant rate by the body (depending on muscle mass). (aidsmap.com)
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. (loinc.org)

Note that urine creatinine concentrations (mg/dL) vary depending on water intake (hydration status) and, therefore, are not very meaningful by themselves. (medscape.com)
Creatinine is found in stable plasma concentrations, freely filtered, not reabsorbed, and is minimally secreted by the renal tubule. (hindawi.com)
Serum concentrations of myoglobin have been proposed as a surrogate marker of muscle mass and function in both cachectic cancer patients and healthy non-cancer individuals. (nottingham.ac.uk)
Age-matched groups had similar serum myoglobin and creatinine concentrations in spite of differences in their aerobic capacity. (nottingham.ac.uk)
Serum myoglobin is a poor predictor of muscle mass, and serum myoglobin and creatinine concentrations do not predict aerobic performance in CRC patients or healthy matched controls. (nottingham.ac.uk)

The blood creatinine level is used to assess the glomerular filtration rate (GFR) . (medindia.net)
The lab specialist combines your blood creatinine level with several other factors to estimate your GFR. (ucsfhealth.org)

If your kidneys are not working like they should, your serum creatinine level goes up. (cdc.gov)
Your serum creatinine level, age, and sex are used to calculate your GFR number. (cdc.gov)
It is calculated using your serum creatinine level, age, and sex. (kidney.org)
Hepatorenal syndrome is diagnosed when a creatinine clearance rate of less than 40 mL/min is present or when a serum creatinine level of greater than 1.5 mg/dL, a urine volume of less than 500 mL/day, and a urine sodium level of less than 10 mEq/L are present. (medscape.com)

Myoglobin is a haem protein produced in skeletal muscles. (nottingham.ac.uk)
These included creatinine clearance, serum phosphorus, and urine dipstick tests to detect protein (proteinuria) and glucose (glucosuria). (aidsmap.com)
Protein ingestion of 40 grams of essential amino acids immediately after exercise reduced muscle soreness and increased strength and power after 48 hours while those who did not ingest protein remained weaker and had more pain up to 72 hours. (selfgrowth.com)
Creatinine is a waste product that comes from the digestion of protein in your food and the normal breakdown of muscle tissue. (kidney.org)

In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation of glomerular filtration rate (GFR) by use of creatinine and a measure, total lumbar muscle cross-sectional area, reflecting the total muscle mass of an individual, is superior to GFRestimating equations based upon creatinine and demographic variables. (lu.se)
The report by Stehlé et al demonstrates one solution to the interference of muscle mass in the use of creatinine to estimate GFR. (lu.se)
Different ways of taking the muscle mass into account when creatinine-based estimations of GFR have been used generally include use of controversial race and sex coefficients. (lu.se)
It is currently unknown whether CER is comparable with healthy controls after transplantation and whether it reflects muscle performance besides muscle mass. (rug.nl)
CONCLUSIONS: Muscle mass as measured by CER in RTR is lower compared to controls. (rug.nl)
The results demonstrate that CER does not only reflect muscle mass but also muscle performance in this patient setting. (rug.nl)
Determination of CER could be an interesting addition to the imaging technique armamentarium available and applied for evaluation of muscle mass in clinical intervention studies and observational studies. (rug.nl)
they almost always reflect low muscle mass. (medscape.com)
[ 9 ] Iinterindividual differences in muscle mass that are related to gender, age, and ethnicity (among other things) are the cause. (medscape.com)
The normal serum creatinine (sCr) varies with the subject's body muscle mass and with the technique used to measure it. (wikipedia.org)
For the adult female, with her generally lower muscle mass, the normal range is 0.5 to 1.1 mg/dl, or 44 to 97 μmol/L by the enzymatic method. (wikipedia.org)
SIGNIFICANCE STATEMENT Low muscle mass is related to frailty and increased mortality in older adults . (bvsalud.org)
However, muscle mass is not easily assessed in routine clinical practice. (bvsalud.org)
These results are consistent with the hypothesis that creatinine filtration may be an index of muscle mass, which may have utility in clinical practice. (bvsalud.org)
Lower CMI was associated with frailty and increased mortality , two clinical outcomes known to be associated with decreased muscle mass. (bvsalud.org)
Measurements may be biased in infants, the elderly, obese patients or those with low muscle mass. (uniprix.com)
Adequate nutritional intake and an optimal training program are important elements of any strategy to preserve or increase muscle mass and strength during aging. (medsci.org)
Muscle strength plays an important role in determining risk for falls in older adults [ 2 ] with muscle mass declining between 3-8% each decade after 30 years of age [ 3 ]. (medsci.org)
AT had significant correlation with lean muscle mass (LMM) among these groups, but myoglobin and creatinine had poor correlation with LMM and AT. (nottingham.ac.uk)
Muscle mass (MM) will be calculated for men and women using the following formulas using height and weight. (who.int)

The clinical picture of drug-induced myopathies may range from asymptomatic or mild myalgias, with or without muscle weakness, which are likely underreported, to chronic myopathy with severe weakness and rarely, even to massive rhabdomyolysis with acute kidney injury (AKI) [ 1 ]. (degruyter.com)
Muscle pain, weakness, and cramping in patients on statin therapy is often reported as statin intolerance in clinical practice. (medpagetoday.com)

DefinitionCreatinine is a breakdown product of creatine, which is an important part of muscle. (answers.com)
Creatinine is a chemical waste product of creatine. (ucsfhealth.org)
If we know the concentration of an item like creatinine (a by-product of creatine breakdown) in the plasma and in the urine, then we have a good idea of GFR. (robbwolf.com)

Creatinine is a waste product that is produced by the muscles through normal contraction. (uniprix.com)
Creatinine is a product of muscle contraction. (dominiondiagnostics.com)
High-voltage DC often causes a large single muscle contraction that throws the victim away from the source, resulting in a brief duration of contact with the source flow. (medscape.com)

Creatinine clearance progressively decreases with age. (uniprix.com)

Creatinine is the waste product derived from muscle creatinine and is released into the blood at a relatively constant rate. (cdc.gov)
Creatinine is a waste product that comes from broken muscle tissue. (medindia.net)
Creatinine (kree-AT-eh-neen) is a waste product our muscles make at a steady rate during normal daily activity. (kidshealth.org)

Assess severity of muscle symptoms, and individualize treatment accordingly. (medpagetoday.com)

An individual's creatinine clearance is determined using a mathematical calculation and the level of creatine in urine and in the blood. (uniprix.com)
A higher than normal creatinine clearance level can be indicative of anemia or increased blood flow to the heart. (uniprix.com)
A lower than normal creatinine clearance level may indicate that the kidneys are not working to their full capacity. (uniprix.com)
Usually a creatinine level more than 1.2 for women and more than 1.4 for men may be a sign that the kidneys are not working like they should. (cdc.gov)
There, the creatinine level in the blood sample is tested. (ucsfhealth.org)
Because it is produced from within and released into body fluids at a relatively constant rate, the level of creatinine in urine may be used as an indication of body hydration. (dominiondiagnostics.com)
Doctors often do the test along with a blood test to measure the creatinine level in the blood to get information about how well the kidneys are working. (kidshealth.org)
Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. (loinc.org)
A "normal" creatinine level in the blood is hard to define because it can change depending on your age, sex, body size, and other factors. (kidney.org)

Talk to your doctor about the meaning of your specific test results.What abnormal results meanAbnormal results of urine creatinine are nonspecific, but may be due to any of the following conditions:GlomerulonephritisHigh meat dietKidney failureMuscular dystrophy (late stage)Myasthenia gravisPrerenal azotemiaPyelonephritisReduced kidney blood flow (as in shock or congestive heart failure)RhabdomyolysisUrinary tract obstructionReferencesBazari H. Approach to the patient with renal disease. (answers.com)

A Novel Creatinine Muscle Index Based on Creatinine Filtration: Associations with Frailty and Mortality. (bvsalud.org)

The increase in serum creatinine is relatively minor at the earliest stages of disease due to mathematical reasons (eg, a patient whose baseline creatinine is 0.6 would have to lose more than 50% of his GFR before the creatinine would increase to 1.3 and first be noted to be "abnormal" by most reference intervals). (medscape.com)

We aimed to compare urinary CER and muscle performance between RTR and healthy controls and to investigate whether urinary CER is associated with muscle performance in RTR. (rug.nl)

In addition, the urine creatinine is used to standardize the collection of urine analytes such as environmental chemicals. (cdc.gov)
A urine creatinine test might be done on a single urine sample or by measuring creatinine in a 24-hour collection of urine. (kidshealth.org)

It may present as asymptomatic or mild myalgias, with or without muscle weakness, which are likely underreported. (degruyter.com)
A type of neuropathy resulting in pain, weakness and/or wasting in the muscles. (diabetes.org)

One of these, an automated dry-slide enzymatic method, measures ammonia generated when creatinine is hydrolyzed by creatinine iminohydrolase. (wikipedia.org)

In some of cases, more accurate information on the GFR can be obtained from a 24-hour creatinine clearance, which requires an accurate 24-hour urine collection and measurement of urine and serum creatinine. (medscape.com)
Creatinine measurement is useful in the diagnosis and treatment of renal diseases, in monitoring renal dialysis, and is used to standardize other urinary analytes (e.g. environmental chemicals). (cdc.gov)

It measures creatinine, a breakdown product of muscle tissues, and factors in a patient's age and sex. (scienceblog.com)
The mechanism is microtrauma to muscles with release of creatinine kinase and then microtrauma to surrounding connective tissues. (selfgrowth.com)
Studies indicate that certain supplements can prevent Delayed Onset Muscle Soreness (DOMS), which occurs when free radicals cause oxidation and inflammation of tissues. (selfgrowth.com)

[ 2 ] The GFR can also be calculated from the creatinine clearance (see below). (medscape.com)
Creatinine clearance is used, among other things, to detect early stage kidney disease, to adjust medication dosages and to monitor the adverse effects of certain medications on the kidneys. (uniprix.com)
A mathematical formula is used to calculate creatinine clearance. (uniprix.com)
It may also be used as part of the creatinine clearance test. (answers.com)
As a result, clearance of the endogenous biomarker creatinine is the most widely used approach. (hindawi.com)
Although not the perfect marker, it is easily measured in blood and urine and creatinine clearance (CrCl), over a defined time interval (usually 24 hours), is used as a surrogate measure of GFR. (hindawi.com)
Creatinine clearance declined slightly but significantly four weeks after starting therapy with Truvada and this decline persisted for the duration of treatment. (aidsmap.com)
The authors believe their findings support recommendations for the routine monitoring of creatinine clearance among people taking Truvada PrEP. (aidsmap.com)
However, creatinine clearance normalised after the cessation of therapy (-0.0 vs 0.0 ml/min). (aidsmap.com)
The effect of Truvada on creatinine clearance was unaffected by known risk factors for kidney dysfunction, including hypertension, race, age and higher body BMI. (aidsmap.com)
HA620 trade name] should not be used for PrEP in HIV-1 uninfected individuals with estimated creatinine clearance below 60 ml/minute. (who.int)

Journal of cachexia sarcopenia and muscle , 10 (3), 621-629. (rug.nl)

If your serum creatinine test results are higher than normal, your doctor may want to run other tests. (cdc.gov)
The loss of water molecule from creatine results in the formation of creatinine. (loinc.org)

Muscle performance was assessed by handgrip strength, sit-to-stand test, and 2-min walk test. (rug.nl)
See: Serum creatinineAlternative NamesUrine creatinine testHow the test is performedA random urine sample or a 24-hour collection may used. (answers.com)
Creatinine can also be measured by a blood test. (ucsfhealth.org)
What Is a Urine Creatinine Test? (kidshealth.org)
For a 24-hour creatinine test, you'll collect all the pee your child passes over 24 hours. (kidshealth.org)
If you have questions about the urine creatinine test, talk to your doctor. (kidshealth.org)
Curcumin - study subjects starting 200 mg of curcumin twice a day 48 hours prior to a downhill running test had reduced muscle pain. (selfgrowth.com)
This test is not as common as the creatinine test and can be more expensive. (kidney.org)

I might recheck CPK in a couple of months, when there is a modest CPK elevation in the presence of mild muscle symptoms, but a CPK that is 5 times normal almost always constitutes statin-induced myopathy," says Dr. Eckel. (medpagetoday.com)

How is the calculation of 24 hour urine creatinine done? (answers.com)

Anatomy56

Organisms16

Diseases36

Chemicals and Drugs54

Analytical, Diagnostic and Therapeutic Techniques and Equipment47

Psychiatry and Psychology1

Phenomena and Processes49

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture1

Information Science3

Health Care17

Amount of creatinine5

Excretion3

Renal function5

EGFR11

Skeletal muscle12

Metabolism3

Kidney function5

Liver5

Byproduct of muscle1

Mmol2

Cystatin5

Levels31

Body entirely by the kidneys1

Urea2

Albumin10

Creatine phosphate3

Concentrations5

Blood creatinine level2

Serum creatinine level4

Protein4

Mass20

Clinical2

Product of creatine3

Contraction3

Decreases1

Waste product3

Assess1

Level9

Nonspecific1

Filtration1

Abnormal1

Healthy1

Collection of urine2

Weakness2

Ammonia1

Measurement2

Tissues3

Clearance11

Sarcopenia and muscle1

Results2

Test8

Normal1

Calculation1