• The results will be of central interest in basic studies of cochlear mechanism, because they will delineate the capabilities of OHC motility for energy input to the cochlea. (grantome.com)
  • This is a necessary precondition for serious theoretical and experimental examination of the role of OHC motility in cochlear function and pathology. (grantome.com)
  • Rho GTPases mediate the regulation of cochlear outer hair cell motility by acetylcholine. (cytoskeleton.com)
  • Along the way OAEs led to new discoveries, including hair cell motility, contralateral cochlear suppression, and auditory neuropathy discoveries that have yet to have their full impact on audiology. (hearingreview.com)
  • Finally, in a fifth study, OHC motility will be used as an assay to determine the somatic location of voltage-dependent conductances. (grantome.com)
  • active hair bundles and somatic motility. (bris.ac.uk)
  • Somatic length changes due to transcellular electrical stimulation were measured at the cuticular plate in the inserted portion of the cells. (northwestern.edu)
  • Somatic cell motility and active motility of the hair bundle, mechanically sensitive structure on the hair cell apex, are two main mechanisms by which hair cells can amplify mechanical stimuli. (ohio-forum.com)
  • Yet, the same cells demonstrate spontaneous electrical oscillation of their somatic potentials, a signature of another amplification mechanism. (ohio-forum.com)
  • Cilia and flagella are hair-like projections found on the surface of virtually every vertebrate cell. (harvard.edu)
  • Cilia are organelles used by myriads of eukaryotic cells to stir and sense the surrounding fluids. (findaphd.com)
  • In addition, we provide evidence that many cell types, including dopaminergic neurons, cannot form cilia when aggresomes are present, which would affect their ability to receive extracellular signals. (biorxiv.org)
  • Cilia or flagella of eukaryotes are small micro-hair like structures that are indispensable to single-cell motility and play an important role in mammalian biological processes. (go.jp)
  • A new study of a protein found in cilia - the hair-like projections on the cell surface - may help explain how genetic defects in cilia play a role in developmental abnormalities, kidney disease and a number of other disorders. (princeton.edu)
  • The researchers at Princeton University and Northwestern University found that the protein, which goes by the name C21orf59 or "Kurly," is needed for cilia to undulate to keep fluid moving over the surface of cells. (princeton.edu)
  • It's extremely exciting that we've found a single protein that is responsible for these two functions - orientation and motility - in cilia," said Rebecca Burdine , an associate professor of molecular biology at Princeton University. (princeton.edu)
  • Despite their importance in human disease, very little is known about how cilia motility and orientation are coordinated, so this protein will provide an important gateway into looking at this process. (princeton.edu)
  • Caption: Staining of cilia (hair-like projections in green and nuclei in blue) in zebrafish kidney tubules show cilia are disorganized and oriented incorrectly in fish with mutated Kurly protein (bottom panel) versus normal Kurly (top panel). (princeton.edu)
  • In frogs, the cilia on skin cells help move fluid along the surface of the animal during its larval stage. (princeton.edu)
  • Cilia are microtubule -based structures that either transmit information into the cell or move fluid outside of the cell. (xenbase.org)
  • Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis. (xenbase.org)
  • These hair-like structures provide motility to microorganisms and clear our lungs of germs, but they also drive fluid flow in organs as diverse as the reproductive system and the brain. (findaphd.com)
  • It is unclear if these aggregates or Lewy bodies are a means to protect the cell from smaller unfolded units of α-syn or if these structures cause neuronal death by obstructing the normal function of the cell. (biorxiv.org)
  • Prostate-specific antigen (PSA) dilutes the semen so the sperm cells with tadpole-like structures can whirl in the fluid. (aldergrovestar.com)
  • Pili or fimbriae are protein structures that extend from the bacterial cell envelope for a distance up to 2 u03bcm (Figure 3). (urhelpmate.com)
  • Several authors have theorized that an ectodermal-mesodermal interaction stimulates hair development and growth of adjacent dermal structures. (medscape.com)
  • In this model, motility is thought to be driven by a large number of independently-acting motor molecules located in the membrane of the cell's lateral wall. (grantome.com)
  • The basic principles of this local control are illustrated in the images below and are outlined as follows: First, an anatomic barrier exists between perilymph and endolymph, and it consists of Reissner membrane, the stria vascularis, and the reticular lamina formed by tight junctions between the apices of hair cells and the adjacent supporting cells (see the image above). (medscape.com)
  • Calcium flux through membrane depolarisation was discovered in 1974, involving the radical pair mechanism at ELF up to MHz, as in modulated cell phone signals. (microwavesicknessinfo.com)
  • Others extend part of their cell membrane and cytoplasm to propel themselves forward. (projectbr.com)
  • One is probably related to conformational changes of the voltage-to-movement converter molecules and a change in their number in an effective operational pool, the other operates via changing the electrical resistance of the basolateral cell membrane. (northwestern.edu)
  • Thus, the cumulative effect of vitamin E, selenium, zinc, folic acid, and n-3 polyunsaturated fatty acids (PUFA) on sperm motility and membrane properties was investigated in healthy normospermic dogs. (mdpi.com)
  • Fungi produce useful food products, and involved in food … Protozoaare non-phototrophic, unicellular, eukaryotic microorganisms with no cell walls. (projectbr.com)
  • CONCLUSION: Our findings indicate that miR2911, an active component present in Lonicera japonica exosomes, inhibits proliferation and induces apoptosis of cervical cancer cells by targeting the E6/E7 genes of HPV16/18. (bvsalud.org)
  • ACh challenge evokes greater magnitude responses in basal turn OHCs, whereas GABA induces greater motility response decrease in apical turn OHCs. (northwestern.edu)
  • Of course, that might not be such bad advice, but why it might be reasonable advice has absolutely nothing to do with sperm counts, sperm motility, or infertility. (scienceblogs.com)
  • These are thin long hair like and helical appendages that protrude through the cell wall originated from the basal granule. (foodtechnotes.com)
  • These are small, thin hair like non helical appendages. (foodtechnotes.com)
  • long proteinaceous appendages on their cell surface, called pili or fimbriae. (urhelpmate.com)
  • Fimbriae and pili are hair-like appendages present on the bacterial cell wall similar to flagella. (urhelpmate.com)
  • and has multiple hair-like appendages, called pili, all over that help with adhesion to other cells. (osmosis.org)
  • He showed that specialised cells known as outer hair cells are responsible for this unique function. (wikipedia.org)
  • In response to sound, outer hair cells lengthen then shorten through a process controlled and powered by the flow of electrically charged molecules such as potassium ions. (wikipedia.org)
  • Modulation of ion channels in outer hair cells from the mammalian cochlea. (wikipedia.org)
  • Local models are reviewed for the pickup mechanism, within the outer hair cells of the organ of Corti. (bris.ac.uk)
  • Outer hair cells (OHC) from high- and low-frequency regions were separately isolated from guinea pig cochleas. (northwestern.edu)
  • The long-term objective of these studies is to elucidate the mechanism of fast outer hair cell (OHC) motility. (grantome.com)
  • An important secondary benefit of these studies is their contribution to cell biology about an extraordinarily fast motility mechanism, one that is unlike anything seen elsewhere to date. (grantome.com)
  • The mechanism of miR2911 action on HPV and the effect of exosomal miR2911 on HPV-induced cervical cancer cells were investigated. (bvsalud.org)
  • In amphibians and some reptiles active processes in hair cells result in noisy mechanical oscillation of hair bundles, which may lead to frequency selective amplification. (ohio-forum.com)
  • In summary, Birt-Hogg-Dubé syndrome is an autosomal dominant disorder clinically manifested by fibrofolliculomas, renal cell carcinoma, lung cysts, and spontaneous pneumothorax. (medscape.com)
  • E6 and Metabolic syndrome and risks of colon and rectal renal cell carcinoma. (who.int)
  • Géraldine Guasch, in Biology and Engineering of Stem Cell Niches, 2017. (patriciamaeolson.com)
  • Some prokaryotic cells also have pili, which are adhesive hair-like projections used to exchange genetic material during a type of sexual process called conjugation, according to Concepts of Biology. (urhelpmate.com)
  • Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets. (cytoskeleton.com)
  • P. aeruginosa produces several virulence factors to help it invade epithelial cells and survive an attack from the immune system . (osmosis.org)
  • Cells in the epithelial tissue are held together with very little intercellular material (matrix). (psebsolutions.com)
  • Pili are small hairs that enable some pathogens to attach and adhere easily to cell surfaces particularly mucous membranes. (urhelpmate.com)
  • What is the function of the pili in a bacterial cell? (urhelpmate.com)
  • Various cell-surface multisubunit protein polymers, known as pili or fimbriae, have a pivotal role in the colonization of specific host tissues by many pathogenic bacteria. (urhelpmate.com)
  • We find that when aggresomes are present, neuronal cells are unable to organise their microtubule network. (biorxiv.org)
  • Due to the high heterogeneity of neuronal cells, until recently, it was not possible to group brain cell types at high resolution. (bvsalud.org)
  • Mechanisms regulating cardiomyocyte cell cycle arrest are of great interest partly because reversing this process could provide a way to stimulate cardiac regeneration after injury [ 17 ]. (springer.com)
  • The Physics & Astronomy Colloquium Series presents Alexander Neiman of Ohio University on "Nonlinear dynamics of noisy hair cells" on Friday, Nov. 6, at 4:10 p.m. in Walter 245. (ohio-forum.com)
  • Mathematical members will utilize both mechanistic principles and individual cell data to discover interaction rules in many-particle biological systems that depend on both local interactions and environmental factors. (clarkson.edu)
  • A main goal will be to use both mathematical modeling and learning techniques to understand fundamental scientific principles by which cells interact, and how this interaction depends on the local microenvironment. (clarkson.edu)
  • In the process of caner recovery, Huaier simultaneously promotes significant hair growth and restoration as a typical evidence of its efficacy on induced tissue regeneration and repair function. (fortunejournals.com)
  • The blood samples from volunteer cancer patients and normal healthy controls were collected and produced by next generation sequencing, and searched for significant alterations in genetic level specifically focused on all the signaling networks related to hair growth and restoration, and also related to Huaier effects on tissue regeneration and repair. (fortunejournals.com)
  • The molecular basis of hair growth was identified as the activation of Hedgehog signaling pathway, which initiates systematic tissue repair not only in cancer lesions together with the cure of skin problems and perturbed inter/ intra neural signal transfer. (fortunejournals.com)
  • Small nuclear RNA analysis revealed that the regulation of tissue regeneration, including hair growth were based on the miRNA-mediated transcriptional control of the pluripotency of stem cells. (fortunejournals.com)
  • Altered cell movement can also be characteristic of pathological conditions, for example, cancer cells invasion to healthy tissue. (clarkson.edu)
  • The zebrafish and Xenopus kidney are outlined in white dashed lines, and motile multiciliated cells in the kidney are pseudocolored in magenta. (xenbase.org)
  • The flagella helps in swimming motility of the bacterial cell. (foodtechnotes.com)
  • Each cell may have several flagella and some bacteria can rotate them at up to 1,500 times per second so that they act in a similar way to a propeller, allowing a bacterium to travel 10 times its length every second. (urhelpmate.com)
  • Which is considered to be the main arena of cellular activities in plant and animal cells? (psebsolutions.com)
  • Reserve material in prokaryotic cells are stored in the cytoplasm in the form of inclusion bodies. (psebsolutions.com)
  • The cells are usually large and polygonal, containing abundant eosinophilic cytoplasm, a large nucleus with open chromatin, a prominent eosinophilic nucleolus, and an occasional intracellular lumina containing red blood cells 1,4-7 . (bvsalud.org)
  • The morphology of bacterial cell includes characteristics such as size, shape, structure etc. (foodtechnotes.com)
  • By the discovery of electron microscope in early 1940's the study of structural bacterial cell has been made very easier. (foodtechnotes.com)
  • The morphological characteristic of a bacterial cell is as follows. (foodtechnotes.com)
  • Bacterial cell having less than one complete twist form. (foodtechnotes.com)
  • Some bacterial cell are covered externally by a thin viscous substance which forms covering layer or envelope to the cell. (foodtechnotes.com)
  • a hair or a structure (as on the surface of a bacterial cell) resembling a hair. (urhelpmate.com)
  • a) Name the three types of cell junctions and write their functions. (psebsolutions.com)
  • They develop in a juxtanuclear position, adjacent to the centrosome, the microtubule organizing centre of the cell, and share some protein components. (biorxiv.org)
  • Despite the long-standing observation that aggresomes/Lewy bodies and the centrosome sit side-by-side in the cell, no studies have been done to see whether these protein accumulations impede the organelle function. (biorxiv.org)
  • The Northwestern team showed that when the kur gene was inactivated using a gene-editing technique called CRISPR-Cas9, the lack of a functioning Kurly protein led to the mis-positioning of a second protein on the cell surface called Prickle2, which helps cells know which direction they face. (princeton.edu)
  • Consume more healthy protein in your diet, as protein deficiency can cause hair pigmentation to fade quickly, Eat more seafood if you have no allergies, as this is rich in copper and iodine, helping in melanin production. (patriciamaeolson.com)
  • A pilus is a thin, rigid fiber made of protein that protrudes from the cell surface. (urhelpmate.com)
  • The effects of miR2911 on endogenous E6/E7 mRNA and protein levels were detected in HPV16/18-positive cervical cancer cells by RT-qPCR and Western blotting. (bvsalud.org)
  • In addition, the endogenous E6/E7 mRNA and protein levels were significantly decreased by using miR2911 treatment in HPV16/18-positive cervical cancer cells. (bvsalud.org)
  • Traditional assays struggle with evaluating cell phenotypes over time and correlating time-dependent responses with changes in the extracellular environment. (clarkson.edu)
  • The proliferation and apoptosis of CaSki, SiHa and HeLa cells by the treatment of miR2911 or miR2911-containing exosomes were examined by CCK8, colony formation and flow cytometry assays. (bvsalud.org)
  • POMx (Pomegranate extract) acts as a blood thinner and contains a potent antioxidant called punicalagin that reduces free radicals' prime cause of aging and cell damage. (aldergrovestar.com)
  • Selenium is one of several nutrients known to have antioxidant properties, meaning selenium plays a part in chemical reactions that stop free radicals from damaging cells and DNA. (livescience.com)
  • Since dopaminergic neurons are polarised, ensuring correct localisation of organelles and the effective intracellular transport of neurotransmitter vesicles, loss of centrosome activity could contribute to loss of dopaminergic function and neuronal cell death in Parkinson's disease. (biorxiv.org)
  • Certain cell organelles function in coordinated manner. (psebsolutions.com)
  • Apart from the purified proteins, Cytoskeleton also provides some innovative kits for studying these proteins in cells and in vitro , see related products below for more information. (cytoskeleton.com)
  • Characterizing collective cell behavior in vitro. (clarkson.edu)
  • However, the dimension of an average rod cell prokaryotes E.coli are about 1×3 μm. (foodtechnotes.com)
  • In many prokaryotes the cells remain together in groups and arrangements after division. (foodtechnotes.com)
  • Lewy bodies are observed in several diseases (Parkinson's disease, dementia with Lewy bodies, incidental Lewy Body disease ( Wakabayashi et al, 2012 )) but are not found in healthy cells and are related to the aggresome, a structure found in cells that are processing large amounts of waste, unfolded polypeptide ( Johnston et al, 1998 ). (biorxiv.org)
  • Why and How to Stop It, How to Get Rid of Redness After Popping a Pimple: Keep Your Skin Healthy, 10 Hairstyles For 11 Year Olds With Medium Hair - Dress Up. (patriciamaeolson.com)
  • These are the best natural essential oils for encouraging healthy normal hair growth. (itreallyworksvitamins.com)
  • Cell migration plays a critical role in a number of biological processes such as embryonic development, wound healing, and immune response. (clarkson.edu)
  • Biological members will be involved in image acquisition and analysis of time-lapse images of cultured cells. (clarkson.edu)
  • Tell my hair shedding phase 719 dutasteride study did. (myjuicecup.com)
  • 99:209 -215.doi:10.1007/s11060 - 010 - 0129 -5 cell carcinoma-a population-based study in with and without cervical cancer in Tbilisi, Georgia. (who.int)
  • Add to them the bad habits of smoking and drinking and the motility of men takes a nosedive. (practo.com)
  • Centrosome positioning in interphase cells. (cytoskeleton.com)
  • The juxtanuclear location of the aggresome is shared by the centrosome, the microtubule organising centre of the cell. (biorxiv.org)
  • Using genetically encoded indicators, we found mitochondrial calcium flux and oxidation are regulated by mechanotransduction and demonstrate that hair cell activity has both acute and long-term consequences on mitochondrial function. (elifesciences.org)
  • Their function is assisted by a Na + /Cl - /K + cotransporter located in the marginal cells. (medscape.com)
  • Carbon monoxide decreases the amount of oxygen available to cells, resulting in problems with cell function. (cdc.gov)
  • All bioactive substances regenerate prostate cells and regulate thyroid hormone for the optimal health of the user. (aldergrovestar.com)
  • Estrogen can directly affect the thyroid but when we are talking about the liver, if the thyroid slows down liver clearance, and the liver can't clear estrogen the way it needs to, and the gut motility is slowed and there is high inflammation, women can't release estrogen through the bowels. (littleblackbagmedicine.com)
  • Fruits are a great way to give your body energy, they have also shown to increase the sperm motility in men. (practo.com)
  • I've written several times over the years about the overblown claims of harm attributed, largely-but not exclusively-by cranks, to cell phone radiation. (scienceblogs.com)
  • It's been claimed that radiation from cell phones can cause brain tumors (there's no convincing evidence that this is true ), breast cancer (the evidence for these claims is so incredibly flimsy-and featured by Dr. Oz, to boot! (scienceblogs.com)
  • As I like to say whenever this topic comes up, it is highly implausible based on basic science that cell phone radiation could cause cancer. (scienceblogs.com)
  • The motility of the melanocytes was also delayed by ionizing radiation. (patriciamaeolson.com)
  • In collaboration with Dr. Art, I overcame the technical challenges of simultaneously recording from type I hair cells and their enveloping calyx afferent to investigate this question. (aro.org)
  • Rogaine usage of reasons for assistance of hair fall and include those components simultaneously. (myjuicecup.com)
  • When cells begin to multiply uncontrollably, it gives rise to cancer. (aldergrovestar.com)
  • Absent compelling evidence of a link between cell phones and cancer, then, it is not unreasonable to rely on the basic science and consider the possibility of such a link to be remote. (scienceblogs.com)
  • Cancer Lett, 300:215-224.doi:10.1016/j. squamous cell carcinoma in north-eastern Iran. (who.int)
  • Capsule is sticky in nature, appear as amorphous gelatinous area and is secreted from inner side of cell and gets firmly attached to the surface of cell wall. (foodtechnotes.com)
  • There are a number of studies that indicate this phenomenon as the quality of sperm and motility is decreasing in men every year. (practo.com)
  • Each time of looking into the mirror to examine physical appearance, checking body weight by scale, shampooing the hair at bath or by hair dressers, the self-confirmation of recovery none the less provides positive supportive effects mentally and physically. (fortunejournals.com)
  • Pattern formation in cell differentiation and body form development. (clarkson.edu)
  • Alopecia Alopecia is defined as loss of hair from the body. (msdmanuals.com)
  • Motility is determined by both properties of the cells and the extracellular environment. (clarkson.edu)
  • Gene Ontology (GO) enrichment analysis of these genes identified an overrepresentation of genes related to the cell cycle. (biomedcentral.com)
  • We discovered an unprecedented burst of differential expression of cell cycle related genes at one particular point during transition to flowering. (biomedcentral.com)
  • Later in contemplation of an immune response, Burnet added, "The failure of antibody production against autologous cells demands the postulation of an active ability of the reticulo-endothelial cells to recognize 'self' patterns from 'non-self' patterns in organic material taken into their substance" ( 3 ). (cdc.gov)
  • Hair cells are mechanoreceptors transducing mechanical vibrations to electrical signals in the senses of hearing and balance in vertebrates. (ohio-forum.com)
  • We use computational modeling to address intriguing questions of how the interaction of two distinct oscillations, mechanical and electrical, affect spontaneous dynamics, battle noise, and shapes sensitivity of amphibian hair cells to external mechanical signals. (ohio-forum.com)