• Progesterone binds to the CatSper receptor on the sperm membrane and increases intracellular calcium levels, causing hyperactive motility. (wikipedia.org)
  • Vaccinia virus produces four different types of virion from each infected cell called intracellular mature virus (IMV), intracellular enveloped virus (IEV), cell-associated enveloped virus (CEV) and extracellular enveloped virus (EEV). (microbiologyresearch.org)
  • IEV is formed by wrapping of IMV with intracellular membranes, and is an intermediate between IMV and CEV/EEV that enables efficient virus dissemination to the cell surface on microtubules. (microbiologyresearch.org)
  • Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular degradation, antigen presentation, intracellular pathogen destruction, plasma membrane repair, exosome release, cell adhesion/migration and apoptosis. (biomedcentral.com)
  • They continuously synthesize histamine, which is then linked to the carboxyl group of heparin and stored in intracellular granules until the cells receive the appropriate activating stimulus. (healthjade.com)
  • Although still not fully understood, an acidic microenvironment with an inverted pH gradient of extracellular pH (pH e ) lower than intracellular pH (pH i ) appears to impose selective pressures whereby tumor cells must adapt or die [ 10 , 11 ]. (biomedcentral.com)
  • Organisms usually contain large numbers of sphingolipid subspecies (for a pathway based compilation, see www.sphingomap.org) and knowledge about the types and amounts is imperative because they influence membrane structure, interactions with the extracellular matrix and neighboring cells, vesicular traffic and the formation of specialized structures such as phagosomes and autophagosomes, as well as participate in intracellular and extracellular signaling. (sphingolipidclub.com)
  • Natural product anticancer agents enhance intracellular levels of ceramide, a sphingolipid that promotes cell apoptosis. (sphingolipidclub.com)
  • The envelope consists of an inner layer of lipids and virus specified proteins also called membrane or matrix proteins. (lookformedical.com)
  • I am a plant cell biologist and protein biochemist at Oxford Brookes University with expertise in the structure and function of the plant endoplasmic reticulum (ER), membrane proteins and auxin biosynthesis using biochemical techniques as well as high-resolution live cell imaging. (brookes.ac.uk)
  • I further investigated membrane proteins and the targeting of tail-anchored proteins at Sheffield Hallam University. (brookes.ac.uk)
  • Changes in glycan structures and the interactions of these structures with endogenous carbohydrate- binding proteins, known as lectins, are now considered to be potential biomarkers on cancer cells for monitoring tu- mor progression. (fdocuments.net)
  • Their unique hourglass-shaped architecture is highly conserved among different bacterial membrane proteins and other biological channels. (ibecbarcelona.eu)
  • Cadherins are single-pass transmembrane glycoproteins that form homotypic interactions with cadherin proteins on neighboring cells and interact intracellularly with proteins of the catenin family [ 4 , 5 ]. (oncotarget.com)
  • Matrix assisted laser desorption ionization (MALDI) mass spectrometry is commonly used to analyze biological molecules such as proteins, peptides and lipids from cells or tissue. (koreascience.kr)
  • Of the 5379 expected proteins in prototype UPEC strain CFT073, only six proteins met all of our founded criteria: (1) surface exposure (expected and shown), (2) induction during growth in human being urine, (3) high manifestation in experimentally infected mice Minocycline hydrochloride and (4) high manifestation in ladies with UTI, (5) immunogenicity, and (6) pathogen-specificity. (morainetownshipdems.org)
  • Transcriptional integration of upstream signaling Examination of M6 unveiled an enrichment for TFs together with other nuclear proteins involved in cell cycle regulation, chromatin modifications, and epigenetic regulation. (hdac-inhibitors.com)
  • The proteins of such MAPKs increased and were then repress UniProt differential download Sarkozy, Israël et whereby steps include to the spliced group before any further cell. (erik-mill.de)
  • The assembly of protein complexes and compositional lipid patterning act together to endow cells with the plasticity required to maintain compositional heterogeneity with respect to individual proteins. (biomedcentral.com)
  • Moreover, lateral motility of membrane proteins was analyzed by calculating diffusion coefficients and kymograph analysis, which represented an alternative method for examining protein motility. (biomedcentral.com)
  • Materials and Methods Cell lines, plasmids, recombinant proteins All cells were maintained in DMEM (4.5?g/L glucose) supplemented with 10% FBS and Penicillin/Streptomycin (Gibco). (healthweblognews.info)
  • MDR1 codes for P-glycoprotein (P-gp), a member of the ABC transporter superfamily of proteins that promote cellular efflux of chemotherapeutic agents. (sphingolipidclub.com)
  • Other cellular components of the innate immune system include mononuclear phagocytes, dendritic cells, and NK cells. (medscape.com)
  • Another distinctive feature of a cellular structure regarded as an "organelle" is when it has a biological membrane that compartmentalizes its contents. (biologyonline.com)
  • TNT cellular networks are upregulated between cancer and stromal cells under hypoxic and other conditions of physiologic and metabolic stress. (frontiersin.org)
  • It differs from bone, however, in that its cellular constituents (odontoblasts) form a layer over the surface of the dentine, from which long tubular processes ramify through the tissue. (clinicalgate.com)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Retroviral particles must bind specifically to their target cells, cross the plasma membrane, reverse-transcribe their RNA genome, while uncoating the cores, find their way to the nuclear membrane and penetrate into the nucleus to finally dock and integrate into the cellular genome. (biomedcentral.com)
  • During the long journey from the cell surface to the nucleus, retroviruses will face multiple obstacles, since in addition to finding a path through the cytoplasm to the nucleus they have to cross two main barriers, the plasma and nuclear membranes, whilst at the same time avoiding or counteracting cellular defences that can interfere with many of these steps. (biomedcentral.com)
  • Lysosomes are membrane-bound compartments that degrade macromolecules and clear damaged organelles to enable cellular adaptation to various metabolic states. (stanford.edu)
  • By developing novel tools and harnessing the power of metabolomics, proteomics and functional genomics, our lab will define 1) how the lysosome communicates with other cellular compartments to fulfill the metabolic demands of the cell under various metabolic states, 2) and how its dysfunction leads to rare and common human diseases. (stanford.edu)
  • HEK293T and HCT116 cellular material were attained from the UNC Cells culture core service. (healthweblognews.info)
  • The sperm plasma then fuses with the egg's plasma membrane and their nuclei fuse, triggering the sperm head to disconnect from its flagellum as the egg travels down the fallopian tube to reach the uterus. (wikipedia.org)
  • In vitro fertilization (IVF) is a process by which egg cells are fertilized by sperm outside the womb, in vitro. (wikipedia.org)
  • Capacitated sperm are attracted to progesterone, which is secreted from the cumulus cells surrounding the oocyte. (wikipedia.org)
  • The sperm must undergo capacitation in the female's reproductive tract, which increases its motility and hyperpolarizes its membrane, preparing it for the acrosome reaction, the enzymatic penetration of the egg's tough membrane, the zona pellucida, which surrounds the oocyte. (wikipedia.org)
  • The sperm binds through the corona radiata, a layer of follicle cells on the outside of the secondary oocyte. (wikipedia.org)
  • A ZP3 glycoprotein on the zona pellucida binds to a receptor on the cell surface of the sperm head. (wikipedia.org)
  • This binding triggers the acrosome to burst, releasing acrosomal enzymes that help the sperm penetrate through the thick zona pellucida layer surrounding the oocyte, ultimately gaining access to the egg's cell membrane. (wikipedia.org)
  • Some sperm cells consume their acrosome prematurely on the surface of the egg cell, facilitating the penetration by other sperm cells. (wikipedia.org)
  • As a population, mature haploid sperm cells have on average 50% genome similarity, so the premature acrosomal reactions aid fertilization by a member of the same cohort. (wikipedia.org)
  • After the sperm enters the cytoplasm of the oocyte, the tail and the outer coating of the sperm disintegrate. (wikipedia.org)
  • The fusion of sperm and oocyte membranes causes cortical reaction to occur. (wikipedia.org)
  • This in turn causes the glycoproteins in the zona pellucida to cross-link with each other - i.e. the enzymes cause the ZP2 to hydrolyse into ZP2f - making the whole matrix hard and impermeable to sperm. (wikipedia.org)
  • In preparation for the fusion of their genetic material both the oocyte and the sperm undergo transformations as a reaction to the fusion of cell membranes. (wikipedia.org)
  • Most of animal cells have cilia e.g. sperm cells. (drelationship.com)
  • The equatorial segment of the acrosome underlies the domain of the sperm that fuses with the egg membrane during fertilization. (bioone.org)
  • The sperm is a specialized reproductive cell that plays a crucial role in fertilization. (microbiologynote.com)
  • The middle piece typically contains energy-producing mitochondria , which provide the necessary ATP (adenosine triphosphate) for sperm motility . (microbiologynote.com)
  • These links are used in cell motility as the actin cytoskeleton generates force pulling the integrin and attached matrix molecules towards the cell center. (biologists.com)
  • On the ventral surface this rearward movement of the cytoskeleton contributes to forward motion of the cell relative to the substrate. (biologists.com)
  • Binding of complement to a foreign substance, or antigen, amplifies and augments the body's innate immune system by means of its role as an opsonin (a factor that enhances phagocytosis of unwanted particles) and as a chemoattractant (a factor that recruits cells to areas of inflammation). (medscape.com)
  • This deregulation may result in production of prostate specific markers such as the secreted protease prostate-specific antigen (PSA) and the cell surface prostate-specific membrane antigen (PSMA) [ 4 ]. (biomedcentral.com)
  • While defects in lipid antigen presentation hN-CoR and in invariant Natural Killer T (iNKT) cell response were detected in several mouse models of lysosomal storage diseases (LSD), the impact of lysosomal engorgement in human lipid antigen presentation is poorly characterized. (clinical-research-informatics.com)
  • Oddly enough, FA was steady in vivo however, not in vitro, with regards to the antigen dosage and the proper period period since T\cell activation, as seen in murine monoclonal T cells. (baxkyardgardener.com)
  • Therefore, we utilized subunit vaccines to research whether homologous vaccination with different P/B intervals (2 vs. four weeks) or changed antigen thickness would influence the FA of the peptide\particular Compact disc8 T\cell response. (baxkyardgardener.com)
  • The generation of receptors specific for antigens is a unique and complex process that generates 10 12 specific receptors for each cell type of the adaptive immune system, including T and B cells. (medscape.com)
  • Various cell types can process and present these antigens to T cells, or antigens may be soluble and bound to B-cell receptors. (medscape.com)
  • Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. (lookformedical.com)
  • Histamine exerts its effects by binding to its 4 receptors [histamine 1 receptor (H1R), H2R, H3R, and and H4R] on target cells in various tissues (see Figure 2 and Table 1). (healthjade.com)
  • Sertoli cells have receptors for FSH. (medicosplexus.com)
  • In tract, markup at cell H3 lysine-5( H3K4) and detailed( H3K36), forming glucose and potential at these receptors, is released synthesized to partially associated kinases( shown in Martin & Zhang 2005). (erik-mill.de)
  • Cortical granules inside the secondary oocyte fuse with the plasma membrane of the cell, causing enzymes inside these granules to be expelled by exocytosis to the zona pellucida. (wikipedia.org)
  • 2) The remaining contents will be sequestered in Rab7-positive late endosomes, which can fuse with the plasma membrane to form exosomes. (biomedcentral.com)
  • 5) Lysosomes can also fuse with the plasma membrane to mediate membrane repair or discharge contents outside the cell, such as cathepsins or immune factors. (biomedcentral.com)
  • Lysosomes are rarely present in cells. (drelationship.com)
  • In addition, previous studies have shown that lysosomes may play important roles in cancer development and progression through the abovementioned biological processes and that the functional status and spatial distribution of lysosomes are closely related to cancer cell proliferation, energy metabolism, invasion and metastasis, immune escape and tumor-associated angiogenesis. (biomedcentral.com)
  • Lysosomes are an important component of the inner membrane system. (biomedcentral.com)
  • Therefore, researchers called lysosomes the "garbage disposals" of cells [ 1 ]. (biomedcentral.com)
  • 6) Lysosomes are the pools of metabolites in cells, including amino acids, sugars, lipids and nucleotides. (biomedcentral.com)
  • Extracellular vaccinia virus formation and cell-to-cell virus transmission are prevented by deletion of the gene encoding the 37,000-Dalton outer envelope protein. (microbiologyresearch.org)
  • They are usually synthesized as protein precursors (POLYPROTEINS) and later cleaved into the final viral envelope glycoproteins by a viral protease. (lookformedical.com)
  • However, hormone receptor negative (triple negative) tumors overwhelmingly overexpress p53 protein in tumor cells. (cancerindex.org)
  • In order for a cell to respond to changes in internal and external environmental factors, a broad range of protein co- and post-translational modifications have evolved to expand upon the relatively static properties encoded in protein side-chains. (biologists.com)
  • I am committed to interdisciplinary research, and an example of the successes gained from this approach is the project with Prof A Nabok (Engineering Sheffield Hallam University) using total internal reflection ellipsometry to quantify protein-membrane interactions on native plant membranes and human cell lines. (brookes.ac.uk)
  • Program access grant to the STFC Harwell Laser Facility 'The Plant Cell Initiative: Protein interactions in the higher plant secretory pathway' 2017-2021 (approximate value of £200K). (brookes.ac.uk)
  • preferentially, post-translational amino-acid JmjC increases are activated provided and conserved to regulate pentose cell polysaccharides with antimicrobial program protein and Clot positions. (erik-mill.de)
  • The results of real-time RT-PCR and western blot showed that the expression level of Cripto-1 was markedly higher in NPC cell lines than that in the immortalized nasopharyngeal epithelial cell at both mRNA and protein levels. (biomedcentral.com)
  • We provided experimental data for the applications of Variable-Angle Epifluorescence Microscopy (VAEM) in dissecting protein dynamics in plant cells. (biomedcentral.com)
  • The present study presented experimental evidence on illustrating the use of VAEM in tracking and dissecting protein dynamics, dissecting endosomal dynamics, cell structure assembly along with membrane microdomain and protein motility in intact plant cells. (biomedcentral.com)
  • We show that the acetylation mimetic GAC.K316Q does not assemble into higher order oligomers and this modification likely inhibits protein activity in cells. (colinsbraincancer.com)
  • Human epididymis protein 4 in association with Annexin II promotes invasion and metastasis of ovarian cancer cells. (gzsys.org.cn)
  • Membrane bound organelles such as Golgi apparatus, mitochondria, ribosomes are present in cell of living organisms . (drelationship.com)
  • 1) membrane-bound organelles (included are double-membraned and single-membraned cytoplasmic structures). (biologyonline.com)
  • Tethered neutrophils enter in membrane-bound vesicles before penetrating into the megakaryocyte cytoplasm. (elifesciences.org)
  • Adenylate cyclase is membrane bound enzyme that catalyzes the formation of cyclic AMP from ATP. (medicosplexus.com)
  • Fluorescence microscopy showed that the trimer and pentamer bound strongly to the cell surface, and within 5 minutes were prominently localized to actin fiber bundles. (biologists.com)
  • It contains membrane-bound spherical bodies called cortical granules, which contain acid mucopolysaccharides. (microbiologynote.com)
  • A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation. (stanford.edu)
  • Opsonins are often antibodies or components of the complement pathway that bind to the surface of target organisms to facilitate this phagocytosis. (medscape.com)
  • Al though it has been shown that EPO induces tyrosine phosphorylation of Stat3 in addition to a likely purpose for this gene continues to be inferred in fetal definitive erythropoi esis through pathway examination, activation of Stat3 is uncommon in hematopoietic cell lines. (hdac-inhibitors.com)
  • cycle, lymphoblastic pathway, and Replication plasma as Strategic Technology Director at actin. (erik-mill.de)
  • Cell-to-cell interactions set off a cascade of events that may result in T- or B-cell activation and, ultimately, host defense. (medscape.com)
  • This is particularly true for galectin family members because changes in their expression levels correlate with alterations in cancer cell growth, apoptosis, and cell-cell and cell-matrix interactions. (fdocuments.net)
  • The structural integrity of these tissues requires extensive cell-cell adhesion and interactions mediated by the adhesive junctional complexes consisting of the adherens junctions and desmosomes [ 2 - 5 ]. (oncotarget.com)
  • This phenomenon occurs in otherwise unmanipulated murine marrow in vivo, resulting in circulating platelets that bear membrane from non-megakaryocytic hematopoietic donors. (elifesciences.org)
  • Moreover, in vivo , the proliferation of the tumor cells was evaluated in xenotransplant nude mice model with whole-body visualizing instrument. (biomedcentral.com)
  • Plant and animal both cells contain well defined nucleus. (drelationship.com)
  • These early steps consist of a long and perilous journey from the cell surface to the nucleus where the proviral DNA integrates into the host genome. (biomedcentral.com)
  • The rough endoplasmic reticulum consists of flattened sacs and is where you will typically find ribosomes attached to its surface, thus, giving it a rough appearance under the microscope. (biologyonline.com)
  • A short-term position at Oxford Brookes just after my PhD allowed me to expand my expertise to ER and Golgi as well as acquiring skills in live cell imaging. (brookes.ac.uk)
  • for example, they provide structural stability to cells and tissues, give motility to individual cells, carry messages within and between cells, and regulate gene expression and metabolism. (biologists.com)
  • Expression of galectins in normal lymphoid cells Each member of the galectin family exhibits a specific expression pattern in distinct tissues, and galectin expression is regulated during development. (fdocuments.net)
  • Epithelial tissues cover the surface of the body and line the internal cavities [ 1 ]. (oncotarget.com)
  • Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. (lookformedical.com)
  • S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility. (gzsys.org.cn)
  • Curcumin, a natural polyphenolic compound derived from turmeric (Curcuma longa L), has proven to be a modulator of multiple intercellular signalling pathways linked to inflammation, to proliferation, growth, invasion, drug sensitivity, angiogenesis and metastasis of cancer cells. (researchgate.net)
  • The time effects of acidic pH e stress were determined with respect to tumor cell proliferation, phenotypic regulation, autophagic control, metabolic plasticity, mitochondrial network dynamics, and metastatic potentials. (biomedcentral.com)
  • Like other solid tumors, PDAC adopts fermentative glycolysis as an additional metabolic mechanism to compensate for the impaired oxidative phosphorylation to support cell survival and proliferation [ 5 , 6 ]. (biomedcentral.com)
  • Aberrant prostate growth arises as a consequence of changes in the balance between cell proliferation and cell death [ 3 ]. (biomedcentral.com)
  • Bioactive sphingolipids in health and disease: lipidomic analysis, metabolism and roles in membrane signaling and autophagy. (sphingolipidclub.com)
  • Inhibitors,Modulators,Libraries Here, the computationally predicted functional purpose for Stat3 in primitive, but not definitive, erythroid cell maturation is validated in vitro. (hdac-inhibitors.com)
  • Inhibition of endogenous Cripto-1 by lentivirus-mediated RNAi silencing technique suppressed NPC cell growth and invasion in vitro . (biomedcentral.com)
  • In this regard we now provide novel information demonstrating that the assembly of higher order fiber-like GAC oligomers henceforth termed the GAC superstructure is necessary for proper enzyme activation both in vitro and in a cancer cell model. (colinsbraincancer.com)
  • Annexin II promotes invasion and migration of human hepatocellular carcinoma cells in vitro via its interaction with HAb18G/CD147. (gzsys.org.cn)
  • Histamine causes smooth muscle cell contraction, vasodilatation (blood vessels to dilate), increased vascular permeability and mucus secretion, tachycardia (increase heart rate), alterations of blood pressure, and arrhythmias (abnormal heart rates or rhythms), and histamine stimulates gastric acid secretion and nociceptive nerve fibers. (healthjade.com)
  • populationbased Acid: high second cell in abnormal proposal. (siriuspixels.com)
  • From plasma membrane endocytosis to exosome secretion, the term "exosome biogenesis" refers to ILV formation in the late endosome, MVBs. (molcells.org)
  • A molecular understanding of membrane traffic has broad implications for our understanding of growth control in cancer, receptor trafficking errors in heart disease, regulation of insulin secretion in diabetes and synaptic vesicle biogenesis and transport in neurological disorders. (stanford.edu)
  • Cell type-specific deletion of the Hdc gene, which encodes HDC (histidine decarboxylase), an enzyme essential for histamine synthesis, would shed light on the role of histamine synthesis and secretion by the minor histamine-producing cells. (healthjade.com)
  • Annexin A2 positively contributes to the malignant phenotype and secretion of IL-6 in DU145 prostate cancer cells. (gzsys.org.cn)
  • Plakoglobin is a component of both the adherens junctions and desmosomes, and therefore plays a vital role in the regulation of cell-cell adhesion. (oncotarget.com)
  • Similar to β-catenin, plakoglobin is capable of participating in cell signaling in addition to its role in cell-cell adhesion. (oncotarget.com)
  • Previous studies have shown that small beads coated with FN7-10, a four-domain cell adhesion fragment of fibronectin, bind to cell surfaces and translocate rearward. (biologists.com)
  • To determine which sites on Raptor had been phosphorylated in cell-free of charge kinase assays, we performed a response as in Fig.?1a, except that unlabeled ATP was found in the response. (healthweblognews.info)
  • Each response was separated using SDS-Web page, stained with Coomassie and the band corresponding to Raptor was excised, trypsin digested, enriched for phosphopeptides and then analyzed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). The peptides identified from the second reaction are presumed to be from another kinase that could be co-purified from cells with HA-Raptor, such as mTOR. (healthweblognews.info)
  • The outer layer of the plant cell wall is primary wall and cellulose is the most common chemical in it. (drelationship.com)
  • General porins are nature's sieving machinery in the outer membrane of Gram-negative bacteria. (ibecbarcelona.eu)
  • Know normal platelet count, increased bleeding time, increased PTT *Captopril is a teratogen *MOA of Amphotericin B  Punches holes in ergosterol of the fungal cell membrane *Tons of biostats. (pdfcoffee.com)
  • Furthermore, they can connect malignant cells to benign cells, including vascular endothelial cells. (frontiersin.org)
  • Some structures of cell are not actually organelles but are very important for it. (drelationship.com)
  • Concerning prostate tumorigenesis, the membrane form of PSMA is predominantly expressed. (biomedcentral.com)
  • Cell theory is a key theory that opened the door of every research in biological field can be related with this theory. (drelationship.com)
  • The biological significance of the small amounts of histamine produced by these minor histamine-producing cells remains unclear. (healthjade.com)
  • These biological nanopores have been designed to protect the interior of the bacterial cell from leakage of toxic compounds while selectively allowing the entry of the molecules needed for cell growth and function. (ibecbarcelona.eu)
  • What is cell in Biology? (drelationship.com)
  • In Biology, cell is define as a building block of all living creature. (drelationship.com)
  • The production of several different virus particles in the VV replication cycle represents a coordinated strategy to exploit cell biology to promote virus spread and to aid virus evasion of antibody and complement. (microbiologyresearch.org)
  • Finally, as proven by many examples in the past, progresses in retrovirology will undoubtedly also provide some priceless insights into cell biology. (biomedcentral.com)
  • The complexity of the sphingolipidome is hard to imagine, but one hopes that, when partnered with other systems biology approaches, the causes and consequences of the complexity will explain how these intriguing compounds are involved in almost every aspect of cell behavior and the malfunctions of many diseases. (sphingolipidclub.com)
  • The aim of this study was to analyze the roles of Cripto-1 in the progression and clinical characteristics in NPC clinical samples and cell lines. (biomedcentral.com)
  • In the present study we examined the relationship between ceramide, ceramide metabolites and expression of the MDR1 gene in human breast cancer cell lines. (sphingolipidclub.com)
  • Variable-angle epifluorescence microscopy (VAEM) allows laser beam to penetrate the cell wall using a sub-critical angle which was smaller than the critical angle [ 10 ]. (biomedcentral.com)
  • These parts include a multitude of cell types that evolve during the course of carcinogenesis and cancer cell progression. (frontiersin.org)
  • In particular, Wnt/-catenin signaling promotes the progression of Osterix1 (Osx1)-expressing cells to bone producing osteoblasts. (tech-strategy.org)
  • Additional histamine-producing cells have also been identified, including T cells 16) , dendritic cells 17) , macrophages 18) , and epithelial cells 19) (Figure ​1). (healthjade.com)
  • Adherens junctions are a ubiquitous type of intercellular junction and are present in both epithelial and non-epithelial cells [ 3 , 6 ], whereas desmosomes are adhesive junctions that confer tensile strength and resilience on cells and are present not only in epithelial cells but also in non-epithelial cells that endure mechanical stress, such as cardiac muscle and meninges [ 7 . (oncotarget.com)
  • months and life on aldosterone of responsible actin blood, population, advanced kidney cell, isoform, and increases assess located. (siriuspixels.com)
  • The most common histologic abnormality was lamina propria hemorrhage (all cases) with many cases also showing lamina propria fibrin deposition with red cell sludging and nuclear debris (7 cases). (stanfordchildrens.org)
  • However, multidrug-resistant (MDR) cancer cells may avoid the cytotoxic effects of chemotherapy by glycosylating ceramide. (sphingolipidclub.com)
  • Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells. (gzsys.org.cn)
  • In contrast, while some studies have suggested a tumor promoting activity of plakoglobin in a cell/malignancy specific context, it generally acts as a tumor/metastasis suppressor. (oncotarget.com)
  • Osteoclasts are bone-resorbing cells of monocyte/macrophage origin and are culprits of bone destruction associated with osteoporosis, rheumatoid arthritis, and cancer bone metastasis. (koreascience.kr)
  • A more malignant state with increased migratory and invasive potentials in long-term acidosis-adapted PDAC cells was obtained with key regulatory molecules being closely related to overall patient survival. (biomedcentral.com)
  • The field of investigation of TNT-mediated tumor-stromal, and tumor-tumor, cell-cell communication is gaining momentum. (frontiersin.org)
  • MIEN1, a novel interactor of Annexin A2, promotes tumor cell migration by enhancing AnxA2 cell surface expression. (gzsys.org.cn)
  • And yet even with this advance, in addition to diffusible soluble factor-mediated paracrine and endocrine cell communication as well as EVs, additional niches of intratumoral communication are filled by other modes of intercellular transfer. (frontiersin.org)
  • The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. (lookformedical.com)
  • Data_Sheet_1.pdf (513K) GUID:?514B8128-1B6A-4BCF-ADFD-8945AF1CB772 Supplementary Body 4: Lipid deposition in cell types of Fabry and Gaucher illnesses. (clinical-research-informatics.com)