• neurogenesis
  • As it had been suggested that deficits in hippocampal neurogenesis might underlie depression, Crusio and collaborators undertook a series of experiments investigating changes in behavior and neurogenesis in mice that had undergone UCMS. (wikipedia.org)
  • However, the results were strain- and sex-specific and there did not appear to be a clear-cut correlation between the different changes, so that they finally concluded that although their data do not disprove the idea that deficits in hippocampal neurogenesis solely underlie the behavioral impairments observed in human psychiatric disorders such as depression, they do not provide support for this hypothesis either. (wikipedia.org)
  • Schaffer
  • The mossy fiber was labeled for mGluR2, mGluR7a, and mGluR7b, whereas the Schaffer collateral was labeled only for mGluR7a. (jneurosci.org)
  • Region CA3 combines this input with signals from EC layer II and sends extensive connections within the region and also sends connections to strata radiatum and oriens of ipsilateral and contralateral CA1 regions through a set of fibers called the Schaffer collaterals, and commissural pathway, respectively. (wikipedia.org)
  • GABAergic
  • Moreover, there is growing evidence for co-localization of GABAergic and glutamatergic neurotransmitters within mossy fiber terminals, though the functional consequence of this co-localization is unclear. (wikipedia.org)
  • projections
  • It has been shown in rodents that the size of the mossy fiber projections can show large interindividual variations, which are to a large part heritable. (wikipedia.org)
  • hilus
  • It receives feedback connections from mossy cells in the hilus at distant levels in the septal and temporal directions. (wikipedia.org)
  • behavior
  • Hirsh, R., Leber, B., & Gillman, K. Fornix fibers and motivational states as controls of behavior: A study stimulated by the contextual retrieval theory. (springer.com)
  • Kimble, D. P., & Kimble, R. J. The effect of hippocampal lesions on extinction and "hypothesis" behavior in rats. (springer.com)
  • dendritic
  • Cerebellar granule cells send parallel fibers up through the Purkinje layer into the molecular layer where they branch out and spread through Purkinje cell dendritic arbors. (wikipedia.org)
  • The dendrite branches project throughout the entire molecular layer and the furthest tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. (wikipedia.org)
  • connections
  • The lamellar concept is still sometimes considered to be a useful organizing principle, but more recent data, showing extensive longitudinal connections within the hippocampal system, have required it to be substantially modified. (wikipedia.org)