• neurogenesis
  • As it had been suggested that deficits in hippocampal neurogenesis might underlie depression, Crusio and collaborators undertook a series of experiments investigating changes in behavior and neurogenesis in mice that had undergone UCMS. (wikipedia.org)
  • However, the results were strain- and sex-specific and there did not appear to be a clear-cut correlation between the different changes, so that they finally concluded that although their data do not disprove the idea that deficits in hippocampal neurogenesis solely underlie the behavioral impairments observed in human psychiatric disorders such as depression, they do not provide support for this hypothesis either. (wikipedia.org)
  • Schaffer
  • The mossy fiber was labeled for mGluR2, mGluR7a, and mGluR7b, whereas the Schaffer collateral was labeled only for mGluR7a. (jneurosci.org)
  • Region CA3 combines this input with signals from EC layer II and sends extensive connections within the region and also sends connections to strata radiatum and oriens of ipsilateral and contralateral CA1 regions through a set of fibers called the Schaffer collaterals, and commissural pathway, respectively. (wikipedia.org)
  • hilus
  • It receives feedback connections from mossy cells in the hilus at distant levels in the septal and temporal directions. (wikipedia.org)
  • dendritic
  • Cerebellar granule cells send parallel fibers up through the Purkinje layer into the molecular layer where they branch out and spread through Purkinje cell dendritic arbors. (wikipedia.org)
  • The dendrite branches project throughout the entire molecular layer and the furthest tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. (wikipedia.org)
  • functional
  • Moreover, there is growing evidence for co-localization of GABAergic and glutamatergic neurotransmitters within mossy fiber terminals, though the functional consequence of this co-localization is unclear. (wikipedia.org)
  • connections
  • The lamellar concept is still sometimes considered to be a useful organizing principle, but more recent data, showing extensive longitudinal connections within the hippocampal system, have required it to be substantially modified. (wikipedia.org)
  • data
  • We demonstrate probability maps and fiber tracking from diffusion tensor data that allows the direct visualization of the perforant pathway. (frontiersin.org)
  • Although it is not possible to validate the DTI data with invasive measures, results described here provide an additional line of evidence of the perforant pathway trajectory in the human brain and that the perforant pathway may cross the hippocampal sulcus. (frontiersin.org)