• The impacts of nutritional support should exceed the limits of nutritional status improvement: EN may directly reduce immunological and infectious events, as well as decrease early transplant-related morbidity and mortality. (biomedcentral.com)
  • Severe alcoholic hepatitis is implicated as a costly, worldwide public health issue with high morbidity and mortality. (wjgnet.com)
  • Coronary artery diseases (CAD) have become a serious epidemic reason of morbidity and mortality. (springeropen.com)
  • Liver transplantation (LT) is an important treatment option for HPS, but it has high mortality and morbidity. (transpopmed.org)
  • However, the risk of developing severe complications, mortality and morbidity after LT remains high, especially in severe HPS. (transpopmed.org)
  • Despite beneficial effects of current glucose-lowering treatments, disease-related morbidity and mortality remain considerable in T2DM patients, galvanising the search for innovative medications that target the multiple metabolic abnormalities as well as inflammatory processes and other pathways predisposing to diabetes-associated disorders. (ddw-online.com)
  • Hepatocellular carcinoma (HCC) one of the most common digestive system tumors, threatens the tens of thousands of people with high morbidity and mortality world widely. (biomedcentral.com)
  • Gamma glutamyl transferase (GGT) was significantly higher in repeat donors (70.5 ± 13.5 μl) than the first time donors (62.5 ± 13.3 μl) (P (scirp.org)
  • Serum total bilirubin, gamma-glutamyl transferase, alkaline phosphatase, ALT and AST should be closely monitored during treatment if elevated values are observed. (pillintrip.com)
  • Whilst alanine transaminase (ALT), creatine kinase (CK), creatinine, and gamma-glutamyl transferase (GGT) concentrations changed substantially at room temperature, there was less than 4% change during chilled storage up to 7 days. (ox.ac.uk)
  • Gamma glutamyl transferase (GGT) is an enzyme found in cell membranes of many tissues mainly in the liver, kidney, and pancreas. (medscape.com)
  • T. Adias, A. Igwilo and Z. Jeremiah, "Repeat Whole Blood Donation Correlates Significantly with Reductions in BMI and Lipid Profiles and Increased Gamma Glutamic Transferase (GGT) Activity among Nigerian Blood Donors," Open Journal of Blood Diseases , Vol. 2 No. 4, 2012, pp. 90-94. (scirp.org)
  • OBJECTIVE: To evaluate the association of atherosclerotic cardiovascular disease (ASCVD) risk factors with incident ASCVD events among type 2 diabetes (T2D) individuals with microvascular complications. (bvsalud.org)
  • Prospective studies in T2DM have shown an association between the degree of hyperglycemia and the risk of micro- and macrovascular complications, including fatal CVD events. (ddw-online.com)
  • Key secondary endpoints include overall survival (OS) and incidence of adverse events (AEs). (wapakdailynews.com)
  • In a study of postmenopausal women with documented coronary heart disease or at increased risk for coronary events, raloxifene did not affect the incidence of myocardial infarction, hospitalized acute coronary syndrome, overall mortality, including overall cardiovascular mortality, or stroke, compared to placebo. (pillintrip.com)
  • The incidence of stroke mortality was 2.2 per 1000 women per year for raloxifene versus 1.5 per 1000 women per year for placebo. (pillintrip.com)
  • In patients, children or adults, with severe congenital, cyclic, or idiopathic neutropenia with an absolute neutrophil count (ANC) of ≤ 0.5 × 10 9 /l, and a history of severe or recurrent infections, long term administration of Neupogen is indicated to increase neutrophil counts and to reduce the incidence and duration of infection-related events. (medicines.org.uk)
  • REZUROCK has been well tolerated and adverse events have been consistent with those expected in patients with advanced cGVHD receiving corticosteroids and/or other immunosuppressants. (yahoo.com)
  • Compared to NSBB, EBL is associated with a lower rate of adverse events, however, potential adverse events of EBL could be more severe and life-threatening (e.g. (springer.com)
  • A total of five adverse events (1.70%) and one serious adverse event (0.34%) were related to the pathway in target group. (jgc301.com)
  • Most common adverse drug reactions (≥5%) from clinical trials in pediatric patients were anemia, vomiting, increased gamma-glutamyltransferase, and cholestasis. (drugs.com)
  • Two hundred forty patients treated with allo-HSCT for a haematological malignancy will be randomly assigned to two groups to receive either EN or PN. (biomedcentral.com)
  • In another study, remdesivir was shown to decrease the likelihood of patients requiring high-flow supplementary oxygen and invasive mechanical ventilation, as well as the risk of 14-day mortality, when compared to the placebo ( 8 ). (spandidos-publications.com)
  • In building a HCC prediction model, deaths and liver transplantations should be considered as competing events because many ALD patients experience hepatic decompensations and deaths before HCC is detected. (nature.com)
  • Bristol Myers Squibb (NYSE: BMY) today announced the Phase 3 CheckMate -77T trial met its primary endpoint of improved event-free survival (EFS) as assessed by Blinded Independent Central Review (BICR) in patients with resectable stage IIA to IIIB non-small cell lung cancer (NSCLC). (santaclara.com)
  • The risk-benefit balance should be considered in patients at risk of venous thromboembolic events of any aetiology. (pillintrip.com)
  • However, the recent ACCORD and ADVANCE trials in patients with longstanding T2DM have shown that aggressive glucose control in such patients has no clear benefits, or may even increase CVD events (3). (ddw-online.com)
  • DoR, based on a later cutoff date than CR/CRi, was defined for patients who achieved CR/CRi per investigator's assessment as time since first response of CR/CRi per investigator's assessment to the date of a progression-free survival (PFS) event or censoring date if no PFS event was documented. (pfizerpro.com)
  • Evolving data suggests that, contrary to intuition, liver transplant recipients and patients with autoimmune liver disease on immunosuppression do not have increased mortality. (xiahepublishing.com)
  • In the INO-VATE ALL trial, a higher post-HSCT non-relapse mortality rate was observed in patients receiving BESPONSA compared to the Investigator's choice of chemotherapy arm, resulting in a higher Day 100 post-HSCT mortality rate. (pfizermedicalinformation.com)
  • However, there are little data on in-hospital mortality in patients with HF ≥ 75 years in Spain. (jgc301.com)
  • CONCLUSIONS In-hospital mortality in patients with HF ≥ 75 years between 2016 and 2019 was 12.7%, higher in males and elderly patients. (jgc301.com)
  • Characteristics and in-hospital mortality of elderly patients with heart failure in Spanish hospitals. (jgc301.com)
  • RÉSUMÉ Tous les patients de sexe masculin soignés en psychiatrie et en médecine générale adressés à deux hôpitaux de Basra (Iraq) de septembre 2000 à avril 200l ont été soumis à un dépistage de l'alcoolisme par le test AUDIT (Alcohol Use Disorder Identification Test). (who.int)
  • We recorded patients' em- ing at levels causing detectable biochemical ployment and economic status (monthly abnormalities is associated with mortality or daily income) and consumption of other that is twice that of the normal population psychoactive drugs. (who.int)
  • Over a median follow-up of 11.7 years, a total of 1,180 cases of incident ASCVD were documented, of which 1,040 were CHD, 100 were stroke, and 40 were both CHD and stroke events. (bvsalud.org)
  • The main predictors of mortality were cardiogenic shock, stroke, and advanced cancer. (jgc301.com)
  • The most informative biomarkers for predicting major cardiovascular events were BNP and the urinary albumin-to-creatinine ratio. (medscape.com)
  • We assessed prospectively whether NAFLD predicts future cardiovascular disease (CVD) events among type 2 diabetic individuals, independent of metabolic syndrome features and other classical risk factors. (diabetesjournals.org)
  • COVID-19 is responsible for disproportionately high rates of mortality among the elderly, particularly those with multiple comorbidities ( 9-12 ). (spandidos-publications.com)
  • Severe clinical presentations include acute decompensation and acute-on-chronic liver failure in a patient with chronic liver disease, leading to high mortality. (xiahepublishing.com)
  • It is unclear which core events drive the malignant progression of gliomas. (biomedcentral.com)
  • The expanding list of nontraditional biomarkers is outweighed by the standard risk factors for predicting future cardiovascular events and adds only moderately to standard risk factors. (medscape.com)
  • Hepatocellular carcinoma (HCC), the most common form of primary liver cancer in ALD, is responsible for one-third of ALD-related mortality, and one-third of all HCC-related deaths are attributed to alcohol use globally 2 . (nature.com)
  • Secondary endpoints will compare EN and PN with regards to the main haematological, infectious and nutritional outcomes. (biomedcentral.com)
  • In the univariate Cox regression analysis, the neutrophil‑to‑lymphocyte ratio and haematological malignancy were identified as predictors of progression to severe disease, and albumin levels, the C‑reactive protein‑to‑albumin ratio (CAR) and haematological malignancy were identified as predictors of 28‑day mortality. (spandidos-publications.com)
  • EN and PN need to be prospectively compared in order to assess their impacts and to provide treatment guidelines. (biomedcentral.com)
  • The primary endpoint of the trial is event-free survival (EFS). (santaclara.com)
  • The understanding of such factors is critical to the prevention of cardiovascular morbidities and mortality. (medscape.com)
  • BMIs under 20 and over 25 have been associated with higher all-cause mortality, with the risk increasing with distance from the 20-25 range. (wikipedia.org)
  • NAFLD is recently suggested to be an independent risk for cardiovascular diseases and is also associated with higher cardiovascular mortality [ 4 ]. (springeropen.com)
  • We report on the NEPHA trial: an open-label, prospective, randomised, multi-centre study on two parallel groups, which has been designed to evaluate the effect of EN compared to PN on early toxicity after an allo-HSCT procedure. (biomedcentral.com)
  • Recently published data suggest that enteral nutrition (EN), given as systematic artificial nutrition support, could decrease grade III-IV graft-versus-host disease (GVHD) and infectious events, which are associated with early toxicity after allo-HSCT and then have an impact on early transplant-related mortality (D100 mortality). (biomedcentral.com)
  • In hospitals with ICCU, the in-hospital risk-adjusted mortality tended to be lower (OR = 0.85, 95% CI: 0.72-1.00, P = 0.053). (jgc301.com)
  • There was a trend toward lower mortality in centers with an ICCU. (jgc301.com)
  • In cases where there is a myelo-ablative-conditioning regimen, drug-induced toxicities, immunosuppression-induced infections and acute graft-versus-host disease (GVHD) are responsible for 15-25% of early mortalities (D100 mortality) [ 1 ]. (biomedcentral.com)
  • The aim of the study and the questions in a substantial contribution to the burden of the questionnaire form were fully explained disease and premature mortality [ 2 ]. (who.int)