• opioid
  • Beyond a certain dose of an opioid (e.g. morphine)increase in does will not increase pain relief? (drugs.com)
  • Adverse effects of opioids Common and short term Itch Nausea Vomiting Constipation Drowsiness dry mouth Other Opioid dependence Dizziness Decreased sex drive Loss of appetite impaired sexual function Decreased testosterone levels Depression Immunodeficiency opioid-induced abnormal pain sensitivity Irregular menstruation Increased risk of falls Slowed breathing Like loperamide and other opioids, morphine acts on the myenteric plexus in the intestinal tract, reducing gut motility, causing constipation. (wikipedia.org)
  • The gastrointestinal effects of morphine are mediated primarily by μ-opioid receptors in the bowel. (wikipedia.org)
  • The drug combination morphine/naltrexone (trade name Embeda) was an opioid combination pain medication developed by King Pharmaceuticals for use in moderate to severe pain. (wikipedia.org)
  • morphine being an opioid receptor agonist and naltrexone an opioid receptor antagonist. (wikipedia.org)
  • Morphine-N-oxide (genomorphine) is an active opioid metabolite of morphine. (wikipedia.org)
  • Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with different half-life, with less risk of altered pharmacodynamics. (wikipedia.org)
  • According to a Cochrane review in 2013, extended-release morphine as a opioid replacement therapy for people with heroin addiction or dependence confers a possible reduction of opioid use and with fewer depressive symptoms but overall more adverse effects when compared to other forms of long-acting opioids. (wikipedia.org)
  • Conway
  • Within a year of Sandman's death, Colley and Conway created Orchestra Morphine, a group of Sandman's friends and colleagues who toured to celebrate the music of the band and to raise funds for the Mark Sandman Music Education Fund. (wikipedia.org)
  • Singer and guitarist Laurie Sargent, a member of Orchestra Morphine and former vocalist for the band Face to Face, later joined Colley and Conway in their first post-Morphine musical endeavor, Twinemen. (wikipedia.org)
  • opium
  • Morphine was isolated from opium by the German chemist F.W.A. Sertürner in about 1804. (britannica.com)
  • Morphine is extracted from the dried milky exudate of the unripe seed capsule of the opium poppy ( Papaver somniferum ). (britannica.com)
  • The important constituents of opium are morphine (10 percent), papaverine (1. (britannica.com)
  • The primary source of morphine is isolation from poppy straw of the opium poppy. (wikipedia.org)
  • Licensing opium poppy cultivation in order to locally manufacture and market Afghan morphine, according to this proposal, would create the economic conditions to empower poverty stricken rural Afghans and cut their ties with the illicit poppy trade. (wikipedia.org)
  • One alternative development policy, put forward by the Senlis Council, proposes licensing poppy cultivation in order to make Afghan morphine and other poppy-based medicines and to avoid diversion of opium to illegal traffickers. (wikipedia.org)
  • Morphine-N-oxide can also form as a decomposition product of morphine outside the body and may show up in assays of opium and poppy straw concentrate. (wikipedia.org)
  • narcotics
  • For example, the Harrison Narcotics Act which restricted morphine abuse was passed by Congress in 1914. (news-medical.net)
  • The ADON and the PM nurse before me took the Morphine out of narcotics and administered it without authorization from pharmacy, although they did have the MD order. (allnurses.com)
  • Afghan morphine or "Poppy for Medicine" is an alternative development solution put forward to combat the poverty and public disenchantment caused by international counter-narcotics eradication policies in Afghanistan. (wikipedia.org)
  • Colley
  • Morphine was an American alternative rock group formed by Mark Sandman, Dana Colley, and Jerome Deupree in Cambridge, Massachusetts in 1989. (wikipedia.org)
  • Morphine was formed in 1989 by bassist and vocalist Mark Sandman, a member of the bluesy alternative rock band Treat Her Right, saxophonist Dana Colley, a former member of the local Boston group Three Colors, and drummer Jerome Deupree, who had played with Sandman in the Hypnosonics. (wikipedia.org)
  • opioids
  • Clinical studies consistently conclude that morphine, like other opioids, often causes hypogonadism and hormone imbalances in chronic users of both sexes. (wikipedia.org)
  • Rykodisc
  • In Europe, all Morphine albums appeared on Rykodisc, which made it possible to release the Best Of album with a career spanning track listing. (wikipedia.org)
  • Painkillers
  • The size of a hockey puck, the high-tech gadget is tucked surgically under the skin of the abdomen -- primarily in injury and cancer patients -- and drips morphine and other painkillers from a reservoir directly into the spine. (sfgate.com)
  • semi synthetic
  • Morphine-6-glucuronide 3-Monoacetylmorphine, the inactive 3,- position blocked by esterization (and thus inactive) of a semi-synthetic prodrug to morphine marking the same activity profile as the drug of this article Morphine-N-oxide Buprenorphine-3-glucuronide Vindenes V, Ripel A, Handal M, Boix F, Mørland J (July 2009). (wikipedia.org)
  • medications
  • tell your doctor and pharmacist if you are allergic to morphine, any other medications, or any of the ingredients in morphine suppositories. (empowher.com)
  • do not use rectal morphine if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), procarbazine (Matulane), selegiline (Eldepryl), and tranylcypromine (Parnate) or if you have stopped taking any of these medications within the past 2 weeks. (empowher.com)
  • Instead of prescribing the FDA-approved morphine, known as Infumorph, doctors can order higher concentrations of compounded morphine, or mix it with other medications such as clonidine that enhance the painkiller's effect. (sfgate.com)
  • enzyme
  • In enzymology, a morphine 6-dehydrogenase (EC 1.1.1.218) is an enzyme that catalyzes the chemical reaction morphine + NAD(P)+ ⇌ {\displaystyle \rightleftharpoons } morphinone + NAD(P)H + H+ The 3 substrates of this enzyme are morphine, NAD+, and NADP+, whereas its 4 products are morphinone, NADH, NADPH, and H+. (wikipedia.org)
  • The systematic name of this enzyme class is morphine:NAD(P)+ 6-oxidoreductase. (wikipedia.org)
  • synthesis
  • That means Morphine can still create all your Subtractive Synthesis favorites: Square, Saw and Sine waves. (image-line.com)
  • So there you have synthesis in Morphine, not so scary. (image-line.com)
  • The first morphine total synthesis, devised by Marshall D. Gates, Jr. in 1952 remains a widely used example of total synthesis. (wikipedia.org)
  • This synthesis of morphine features one of the first example of the Diels-Alder reaction in the context of total synthesis. (wikipedia.org)
  • orally
  • Direct application of morphine to her injury requires much less of the drug than she would have to take orally, and it has fewer side effects. (sfgate.com)
  • 1993
  • The B-side of the long-out-of-print 1000-piece pressing of "Cure For Pain" on 7" vinyl called "Sexy Christmas Baby Mine" (1993) rounds out the adventure through Morphine musical history. (wikipedia.org)
  • significantly
  • In the setting of breathlessness at rest or on minimal exertion from conditions such as advanced cancer or end-stage cardiorespiratory diseases, regular, low-dose sustained-release morphine significantly reduces breathlessness safely, with its benefits maintained over time. (wikipedia.org)
  • poppy
  • It will eventually show a report on Morphine showing evidence that it can be cleanly produced from moldy poppy straw which may be cheaper to purchase. (angelfire.com)
  • pharmacist
  • pain clinic suffered severe neurological problems two years ago after a pharmacist apparently made faulty batches of morphine from bulk ingredients to refill their pumps. (sfgate.com)
  • liver
  • A possible explanation is that morphine-N-oxide is rapidly inactivated in the liver and impairment of inactivation processes or enzymes increases functionality. (wikipedia.org)
  • pain
  • Morphine soon began to gain popularity as a pain reliever. (news-medical.net)
  • In its power to reduce the level of physical distress, morphine is among the most important naturally occurring compounds , being of use in the treatment of pain caused by cancer and in cases where other analgesics have failed. (britannica.com)
  • Your doctor may adjust your dose of morphine during your treatment to control your pain as well as possible. (empowher.com)
  • For thousands of chronic pain sufferers, the Medtronic implantable morphine pump has been a godsend. (sfgate.com)
  • Morphine - no pain relief? (drugs.com)
  • Hello everyone, I take morphine exactly as directed by my dr 3 times per day and it does not touch day the pain I suffer from. (drugs.com)
  • It may be that you need morphine plus something like a muscle relaxant and/or an antidepressant/anticonvulsant that also relieves chronic pain like Cymbalta, Lyrica or gabapentin. (drugs.com)
  • Can morphine be taken as a pain relief regiment after aortic valve replacement? (drugs.com)
  • For constant pain, the relieving effect of extended-release morphine given once (for Kadian) or twice (for MS Contin) every 24 hours is roughly the same as multiple administrations of immediate release (or "regular") morphine. (wikipedia.org)
  • band
  • Morphine combined blues and jazz elements with more traditional rock arrangements, giving the band an unusual sound. (wikipedia.org)
  • Lips Like Morphine was first released on May 16, 2006 by the Chicago-based band Kill Hannah and then again released in August on the band's album Until There's Nothing Left of Us. (wikipedia.org)
  • found
  • An investigation by the Tennessee Board of Pharmacy found two jars of compounded solution labeled morphine at the drugstore. (sfgate.com)
  • Investigators also found ethanol and methanol, contaminants sometimes found in poor quality morphine powder. (sfgate.com)