• trisomy
  • One daughter cell has two (and can go on to produce a gamete that can result in trisomy), while the other daughter cell is left without, and can go on to produce a gamete that will result in monosomy. (everything2.com)
  • Systematic experimental investigations of the developmental consequences of autosomal monosomy and of trisomy seem to be an interesting task in view of the great clinical importance of chromosomal abnormalities in prenatal pathology of man ( BouĂ© et al. (springer.com)
  • Chromosomally hypo- or hypermodal gametes, which are responsible for (whole arm) monosomy or trisomy of the embryo, are produced as a consequence of irregular meiotic segregation. (springer.com)
  • Prenatal detection of monosomy 18p and trisomy 18q mosaicism with unexpected fetal phenotype. (bmj.com)
  • mosaic cases
  • However, results are usually not available for 3-4 days or more.Furthermore, we detected two chromosome X monosomy mosaic cases in which the mosaism rates estimated by array-MLPA were basically consistent with the results from karyotyping.Our study demonstrates the successful application and strong potential of array-MLPA in clinical diagnosis and prenatal testing for rapid and sensitive chromosomal aneuploidy screening. (nih.gov)
  • Furthermore, we detected two chromosome X monosomy mosaic cases in which the mosaism rates estimated by array-MLPA were basically consistent with the results from karyotyping. (nih.gov)
  • fluorescence
  • Monosomy 3, detected by cytogenetic analysis, spectral karyotyping, fluorescence in situ hybridization (FISH), comparative genomic hybridization (CGH), and other techniques, may be more accurate than clinical and pathologic features and has been adopted as a molecular prognostic marker in many centers ( 4 - 12 ). (aacrjournals.org)
  • parental
  • The remaining 10-15% are due to unequal segregation of a parental balanced translocation where the 5p monosomy is often accompanied by a trisomic portion of the genome. (wikipedia.org)
  • region
  • Infants born with partial monosomy 13q may exhibit low birth weight, malformations of the head and face (craniofacial region), skeletal abnormalities (especially of the hands and feet), and other physical abnormalities. (wikipedia.org)
  • patients
  • To define the relationship between the status of donor NK-cell receptor and patient outcomes after killer immunoglobulin-like receptor-incompatible unrelated donor (URD) and umbilical cord blood (UCB) hematopoietic cell transplantation (HCT) in young patients with acute myeloid leukemia with monosomy 7, -5/5q-, high FLT3 internal tandem duplication allelic ratio (High-FLT3-ITD AR), or refractory or relapsed acute myelogenous leukemia. (knowcancer.com)
  • Group
  • Two studies found a rate of cardiovascular malformations of 30% and 38% in a group of pure 45,X monosomy. (wikipedia.org)
  • The higher rate in the group of pure 45,X monosomy is primarily due to a difference in the rate of aortic valve abnormalities and coarctation of the aorta, the two most common cardiovascular malformations. (wikipedia.org)
  • study
  • In this study, the prognostic accuracy of the SNP assay was compared with traditional methods for measuring monosomy 3, including array CGH (aCGH) and FISH. (aacrjournals.org)