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Uridine PhosphorylaseUridine KinaseUridine MonophosphateUridine TriphosphateUridine Diphosphate SugarsUracil NucleotidesUridine DiphosphateCyclic AMPCyclic GMPInosine MonophosphateAdenosine MonophosphateUridine Diphosphate GlucoseCytidine8-Bromo Cyclic Adenosine MonophosphateCytidine MonophosphateGuanosine MonophosphatePyrimidine NucleotidesNucleosidesUridine Diphosphate N-AcetylglucosamineIMP DehydrogenaseThiamine MonophosphateUracilHexosephosphatesUridine Diphosphate GalactoseBucladesineKineticsOrotidine-5'-Phosphate DecarboxylaseDeoxycytidine MonophosphateNucleoside-Phosphate KinaseTritiumPyrimidine NucleosidesAdenine NucleotidesRNAUridine Diphosphate Glucuronic AcidTheophyllineOrotic AcidNucleotidesThymidineUridine Diphosphate Glucose DehydrogenaseRibonucleosidesPhosphotransferasesGlucuronosyltransferaseCytosine NucleotidesColforsinThiouridineUridine Diphosphate N-Acetylgalactosamine1-Methyl-3-isobutylxanthineThioinosinePentosyltransferasesNucleoside Transport ProteinsAdenosinePhosphodiesterase InhibitorsDeoxyuridineGuanosineInosine NucleotidesCells, CulturedThymidine MonophosphateNucleotides, CyclicPhosphoric Diester HydrolasesPseudouridineAzauridineMolecular Sequence DataChromatography, PaperAdenosine TriphosphateDibutyryl Cyclic GMPRibonucleotidesGuanylate CyclasePurine NucleotidesUridine Diphosphate XyloseAdenylate CyclasePurinesInosineEscherichia coliCarbon IsotopesPentose Phosphate PathwayCytidine TriphosphateDose-Response Relationship, DrugPurinonesRNA EditingStimulation, ChemicalDolichol PhosphatesPhosphoribosyl PyrophosphateBase SequenceDinucleoside PhosphatesMethylene BlueGlucoseCell LineTime FactorsNitric OxideCalciumPhosphatidylinositolsDolichol Monophosphate MannoseCyclic GMP-Dependent Protein KinasesRNA, GuideGMP ReductaseSubstrate SpecificityBiological TransportAdenineCyclic AMP-Dependent Protein KinasesOrotate Phosphoribosyltransferase

NucleotidesSynthaseCombination of uridineDecarboxylaseNucleosideDeficiencyPhosphatidylserineUracilOrotidineDietaryAcidPyrimidineProteinSynthesisAcetylcholineCompoundFormCatalyzeWikipediaFoundDisodiumCytidineOrotate phosphoribosyltransferaseDocosahexaenoic acidCholineEnzymeOrotic acidNucleotideSupplementationSodiumMetabolismNutrientsNaturallyLiverBrainResearchStudiesTreatment

Nucleotides1

• Dietary nucleotides [inclusion adenosine 5'-monophosphate (AMP)] supplementation was shown to promote the feed intake of sows and increase the AMP content in their milk in our previous work, but whether AMP shapes the energy expenditure and lipid metabolism in mammals remains unknown. (foodandnutritionresearch.net)

Synthase4

• The enzyme Uridine monophosphate synthase (EC 4.1.1.23, UMPS) (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) catalyses the formation of uridine monophosphate (UMP), an energy-carrying molecule in many important biosynthetic pathways. (wikipedia.org)
• In microorganisms, these two domains are separate proteins, but, in multicellular eukaryotes, the two catalytic sites are expressed on a single protein, uridine monophosphate synthase. (wikipedia.org)
• Diagnosis of uridine monophosphate synthase deficiency is by DNA analysis and/or enzyme assay in a variety of tissues. (msdmanuals.com)
• Treatment of uridine monophosphate synthase deficiency is with oral uridine supplementation. (msdmanuals.com)

Combination of uridine1

• In a study, gerbils fed a combination of uridine monophosphate, choline, and docosahexaenoic acid (DHA) were found to have significantly improved performance in running mazes over those not fed the supplements, implying an increase in cognitive function. (wikipedia.org)

Decarboxylase4

• Uridine monophosphate is formed from Orotidine 5'-monophosphate (orotidylic acid) in a decarboxylation reaction catalyzed by the enzyme orotidylate decarboxylase. (wikipedia.org)
• Orotidine-5'-monophosphate decarboxylase (OMPD) catalyzes the decarboxylation of orotidine-5'-monophosphate (OMP) to uridine-5'-monophosphate (UMP) in an extremely proficient manner. (rcsb.org)
• Wise EL, Yew WS, Akana J, Gerlt JA, Rayment I (2005) Evolution of enzymatic activities in the orotidine 5′-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase. (wordnik.com)
• Uridine monophosphate is the enzyme that catalyzes orotate phosphoribosyltransferase and orotidine-5 ′ -monophosphate decarboxylase reactions. (msdmanuals.com)

Nucleoside4

• It is an ester of phosphoric acid with the nucleoside uridine. (wikipedia.org)
• This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. (nih.gov)
• URIDINE (Triacetyluridine) Uridine is a nucleoside that is formed when uracil is attached to a ribose ring. (nutrimedical.com)
• Uridine is a Pyrimidine nucleoside that has dramatic positive physiological effects to reduce abnormal nerve firing patterns in seizure, ADHD and ADD, autism and toxic CNS neuropathy and organic brain syndrome. (nutrimedical.com)

Deficiency2

• Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. (nih.gov)
• Wikipedia, en.wikipedia.org/wiki/Thiamine_deficiency. (purenootropics.net)

Phosphatidylserine1

• Cognitex® Elite Pregnenolone contains SIBELIUS™: SAGE, blueberry and ashwagandha extracts plus phosphatidylserine, vinpocetine, Uridine-5'-Monophosphate (UMP) and the neuro-active hormone pregnenolone. (lifeextension.com)

Uracil1

• Uracil phosphoribosyltransferase (UPRTase) catalyzes the conversion of 5-phosphate-alpha-1-diphosphate (PRPP) and uracil to uridine 5'-monophosphate (UMP) and diphosphate. (rcsb.org)

Orotidine2

• After addition of ribose-P to orotate by OPRTase to form orotidine-5'-monophosphate (OMP), OMP is decarboxylated to form uridine monophosphate by ODCase. (wikipedia.org)
• The net result is the formation of a molecule named OMP ( orotidine 5′-monophosphate), which in turn is the immediate precursor to UMP (uridine 5′-monophosphate). (wordnik.com)

Dietary1

• Monophosphate disodium salt_Dietary supplements ingredients, vitamins and minerals. (health-sources.com)

Acid4

• Uridine monophosphate (UMP), also known as 5′-uridylic acid (conjugate base uridylate), is a nucleotide that is used as a monomer in RNA. (wikipedia.org)
• Folinic acid provides a methyl group to uridine monophosphate, thus forming thymidine monophosphate, overcoming effects of MTX on tetrahydrofolic acid reductase. (medscape.com)
• TAU is rapidly converted to uridine in the cell and escapes acid hydrolysis in the gut. (nutrimedical.com)
• Uridine Monophosphate - An Overview Uridine (Uridine Monophosphate, UMP) is a naturally occurring amino acid. (holisticnootropics.com)

Pyrimidine2

• The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. (nih.gov)
• URIDINE Pyrimidine Acetylcholine RNA DNA Enhanced Production, for ADD ADHD Asperger's Syndrome, CNS Vision Balance Motor Power and Memory and Recall Higher Functions. (nutrimedical.com)

Protein1

• The most horrifying revelation was the sinister presence of "three bladder cancer markers - BTA serine/threonine protein, NMP uridine monophosphate and RCAS1, a receptor-binding cancer antigen. (nationalenquirer.com)

Synthesis1

• Uridine has a crucial influence on important physiologic processes in the human body and is essential for both RNA and DNA synthesis. (nutrimedical.com)

Acetylcholine1

• The uridine monophosphate is known to increase dopamine and acetylcholine levels in the brain. (vitamin-dude.com)

Compound2

• In brain research studies, uridine monophosphate is used as a convenient delivery compound for uridine. (wikipedia.org)
• Uridine is the active component of this compound. (wikipedia.org)

Form1

• Uridine is present in many foods, mainly in the form of RNA. (wikipedia.org)

Catalyze1

• These two sites catalyze the last two steps of the de novo uridine monophosphate (UMP) biosynthetic pathway. (wikipedia.org)

Wikipedia1

• Wikipedia, en.wikipedia.org/wiki/Sulbutiamine. (purenootropics.net)

Found1

• While uridine is not found in high levels in any particular food, it is an important component of human breast milk. (nutrimedical.com)

Disodium6

• Uridine Monophosphate Disodium, a prominent compound in nucleic acid metabolism, emerges as a focal point in neurological research. (bc9.org)
• Uridine Monophosphate Disodium is a nucleotide derivative crucial for RNA synthesis and the formation of cell membranes. (bc9.org)
• Researchers are actively exploring the diverse applications of Uridine Monophosphate Disodium in neuroscience. (bc9.org)
• Uridine Monophosphate Disodium, a vital player in cellular processes, holds promise in various research applications. (bc9.org)
• With potential benefits spanning cognitive function, sleep modulation, and metabolic regulation, Uridine Monophosphate Disodium presents a compelling avenue for further investigation in the realm of neuroscience. (bc9.org)
• Uridine (5′-monophosphate disodium) 50g. (bionootropics.com)

Cytidine3

• Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. (nih.gov)
• This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. (nih.gov)
• This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. (nih.gov)

Orotate phosphoribosyltransferase3

• Uridine monophosphate is the enzyme that catalyzes orotate phosphoribosyltransferase and orotidine-5 ′ -monophosphate decarboxylase reactions. (msdmanuals.com)
• 15. Orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum. (nih.gov)
• The last two enzymes of the pathway, orotate phosphoribosyltransferase and orotidine-5-monophosphate decarboxylase, are fused in a multi-domain enzyme and are duplicated in some P. infestans strains. (unboundmedicine.com)

Docosahexaenoic acid1

• In a study, gerbils fed a combination of uridine monophosphate, choline, and docosahexaenoic acid (DHA) were found to have significantly improved performance in running mazes over those not fed the supplements, implying an increase in cognitive function. (wikipedia.org)

Choline1

• Since Uridine Monophosphate Supplement isn't directly cholinergic, in that it doesn't directly affect acetylcholine production, it serves as a fantastic catalyst when combined with the likes of Alpha GPC choline. (mindnutrition.com)

Enzyme1

• A third enzyme then splits the CO2 off the orotic ribose P, leaving uracil ribose P, also known as uridine monophosphate, which is a complete nucleotide. (nih.gov)

Orotic acid1

• 18. Uracil metabolism--UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs. (nih.gov)

Nucleotide1

• Uridine monophosphate (UMP), also known as 5′-uridylic acid (conjugate base uridylate), is a nucleotide that is used as a monomer in RNA. (wikipedia.org)

Supplementation1

• Uridine supplementation in the treatment of HIV lipoatrophy: results of ACTG 5229. (bc9.org)

Sodium1

• Uridine Monophosphate Sodium (UMP) is a naturally occurring component of RNA which is found in various foodstuffs. (mindnutrition.com)

Metabolism1

• Non-phosphorylated uridine is not bioavailable beyond first-pass metabolism, as it is almost entirely catabolised in the liver and gastrointestinal tract. (wikipedia.org)

Nutrients1

• Life Extension supplements and vitamins can help you on the path to general health and well-being that include nutrients and compounds like uridine-5'-monophosphate for healthy brain tissue, pomegranate extract for its antioxidant properties, and coenzyme Q10 to promote the conversion of fat to energy. (pureformulas.com)

Naturally1

• Uridine Monophosphate - An Overview Uridine (Uridine Monophosphate, UMP) is a naturally occurring amino acid. (holisticnootropics.com)

Liver1

• In addition, HFCS decreased uridine monophosphate and short-chain acyl carnitines in liver, and urea nitrogen and creatinine in serum (P = 0.05). (usda.gov)

Brain2

• For example, your brain needs uridine-5'-monophosphate (and that certainly isn't a household name). (pureformulas.com)
• Uridine-5'-monophosphate (UMP) is a phosphatide building block of RNA-DNA that is critical to optimal brain function and the health of neuronal cell membranes. (lifeextension.com)

Research1

• Research indicates a potential link between Uridine Monophosphate and sleep modulation. (bc9.org)

Studies2

• Studies suggest that Uridine Monophosphate may have positive effects on learning and memory processes. (bc9.org)
• Preliminary studies suggest a connection between Uridine Monophosphate and fat mass regulation. (bc9.org)

Treatment1

• Ocalan B, Cakir A, Koc C, Suyen GG, Kahveci N. Uridine treatment prevents REM sleep deprivation-induced learning and memory impairment. (bc9.org)