Loading...
  • inflammation
  • Here, we show that healthy monocytes can induce the expression of these defensins via Wnt ligands, especially in patients with Crohn's disease (CD), who normally display reduced levels of human α-defensin 5 (HD5) and HD6, resulting in impaired host defense and, consequently, mucosal inflammation. (pnas.org)
  • subtypes
  • Accordingly, analysis of PBMC subtypes showed that monocytes of patients with CD express significantly lower levels of canonical Wnt ligands, including Wnt3, Wnt3a, Wnt1, and wntless Wnt ligand secretion mediator (Evi/Wls). (pnas.org)
  • endothelium
  • Also, through the activation of collagenases, ox-LDL contributes to a process which may lead to the rupture of the fibrous plaque Oxidized LDL decreases the availability of endothelial nitric oxide (NO), which, in turn, increases the adhesion of monocytes to the endothelium. (wikipedia.org)
  • blood
  • Monocytes are one of the five types of white blood cells that normally appear in the blood. (reference.com)
  • Monocytopenia is the medical term associated with a low monocyte blood cell count. (ehow.co.uk)
  • It is most likely that the signs of some type of an infection will be noticed by someone suffering from a low monocyte blood count. (ehow.co.uk)
  • Deficiencies in vitamin B12 and folate may also cause a low monocyte blood count. (ehow.co.uk)
  • A low monocyte blood cell count diagnosis is based on the results of a complete blood count from a sample removed from the patient's vein. (ehow.co.uk)
  • A low monocyte blood cell count increases susceptibility to infections. (ehow.co.uk)
  • https://www.ehow.co.uk/about_5606257_signs-monocytes-blood-cell-count.html. (ehow.co.uk)
  • Signs & symptoms of low monocytes blood cell count" last modified May 13, 2017. (ehow.co.uk)
  • Human blood monocytes in cell culture medium under low magnification using phase-contrast microscopy (40x objective). (asmscience.org)
  • There are at least three subclasses of monocytes in human blood based on their phenotypic receptors. (wikipedia.org)
  • There are at least three types of monocytes in human blood: The classical monocyte is characterized by high level expression of the CD14 cell surface receptor (CD14++ CD16− monocyte) The non-classical monocyte shows low level expression of CD14 and additional co-expression of the CD16 receptor (CD14+CD16++ monocyte). (wikipedia.org)
  • infection
  • The most common reasons for a high level of monocytes are chronic inflammatory disease, leukemia, parasitic infection and tuberculosis. (reference.com)
  • Another common cause for a high level of monocytes is a viral infection, such as infectious mononucleosis, mumps and measles. (reference.com)
  • differentiate
  • While in humans the level of CD14 expression can be used to differentiate non-classical and intermediate monocytes, the slan cell surface marker was shown to give an unequivocal separation of the two cell types. (wikipedia.org)
  • human
  • Hello, We are interested in metabolic labeling (using 35S-Met) human monocytes stimulated under various conditions. (bio.net)
  • Live fetal rodent bones prelabeled with 45 Ca and cultured for 48-96 h in the presence of human monocytes or monocyte-conditioned medium released 80% more mineral than bones cultured in control medium. (springer.com)
  • However
  • However, monocytes from these patients are lacking this defensin-inducing capability, which seems to be based on compromised expression of Wnt ligands. (pnas.org)