Molecules o antigens. Medical search. Frequent questions

Three counter-receptors have been described for LFA-1, intercellular adhesion molecule 1 (ICAM-1), ICAM-2 and ICAM-3. (biovendor.com)
Activated T cells induce proliferation and differentiation of resting B cells in vitro through their CD40 molecules and lymphokine receptors. (uthscsa.edu)
Bishop, GA, Warren, WD & Berton, MT 1995, ' Signaling via major histocompatibility complex class II molecules and antigen receptors enhances the B cell response to gp39/CD40 ligand ', European Journal of Immunology , vol. 25, no. 5, pp. 1230-1238. (uthscsa.edu)
Anti-tumor efficacy of T cells engineered to express chimeric antigen receptors (CARs) is dependent on their specificity, survival, and in vivo expansion following adoptive transfer. (houstonmethodist.org)
A low level of signaling was also obtained when functionalizing the blocked SLBs with adhesion molecules binding to receptors on the T cell. (lu.se)

Antigen-antibody interaction, or antigen-antibody reaction, is a specific chemical interaction between antibodies produced by B cells of the white blood cells and antigens during immune reaction. (wikipedia.org)
The antigens and antibodies combine by a process called agglutination. (wikipedia.org)
In the blood, the antigens are specifically and with high affinity bound by antibodies to form an antigen-antibody complex. (wikipedia.org)
There are several types of antibodies and antigens, and each antibody is capable of binding only to a specific antigen. (wikipedia.org)
Antigens are bound to antibodies through weak and noncovalent interactions such as electrostatic interactions, hydrogen bonds, Van der Waals forces, and hydrophobic interactions. (wikipedia.org)
Acquired immunity depends upon the interaction between antigens and a group of proteins called antibodies produced by B cells of the blood. (wikipedia.org)
There are many antibodies and each is specific for a particular type of antigen. (wikipedia.org)
Antibodies bind antigens through weak chemical interactions, and bonding is essentially non-covalent. (wikipedia.org)
It is so rare to find the T antigen in healthy tissue, that we actually have antibodies against it. (dadamo.com)
All humans normally possess antibodies that react with the Thomsen-Friedenreich (T) and the Tn antigens. (dadamo.com)
After an antigen binds to a BCR, the B cell activates to proliferate and differentiate into either plasma cells , which secrete soluble antibodies with the same paratope, or memory B cells , which survive in the body to enable long-lasting immunity to the antigen. (wikipedia.org)
The immune system responds to antigens by producing cells that directly attack the pathogen, or by producing special proteins called antibodies . (khanacademy.org)
Antibodies attach to an antigen and attract cells that will engulf and destroy the pathogen. (khanacademy.org)
c) Effect of antibodies and antigen-specific B cells on antigen uptake. (hindawi.com)
Acquired immunity comes from antibodies you get from your mother in the womb or that you make in response to antigens that aren't yours -- like from a cold virus or a vaccine. (webmd.com)
Once your B cells get a read on the antigen of a new invader, they make antibodies to either kill it or flag it as "Trouble here! (webmd.com)
Antibodies are proteins that fight infection by attaching to antigens. (cancer.net)
These three test tubes had been used in a Legionella pneumophila bacteria detection test, whereupon, if L. pneumophila were present, as in the case of the middle test tube, antibodies that had been conjugated to fluorescein isothiocyanate (FITC), would attach themselves to the antigen, which in this case were the L. pneumophila organisms. (cdc.gov)

The first correct description of the antigen-antibody reaction was given by Richard J. Goldberg at the University of Wisconsin in 1952. (wikipedia.org)
It came to be known as "Goldberg's theory" (of antigen-antibody reaction). (wikipedia.org)
The principles of specificity and cross-reactivity of the antigen-antibody interaction are useful in clinical laboratory for diagnostic purposes. (wikipedia.org)
Thus immune response in acquired immunity is due to the precise binding of antigens to antibody. (wikipedia.org)
Only very small area of the antigens and antibody molecules actually interact through complementary binding sites, called epitopes in antigens and paratopes in antibody. (wikipedia.org)
In an antibody, the Fab (fragment, antigen-binding) region is formed from the amino-terminal end of both the light and heavy chains of the immunoglobulin polypeptide. (wikipedia.org)
This region, called the variable (V) domain, is composed of amino acid sequences that define each type of antibody and their binding affinity to an antigen. (wikipedia.org)
Thus these regions may be part of a paratope, the part of an antibody that recognizes and binds to an antigen. (wikipedia.org)
Non-covalent bonds between antibody and antigen can also be mediated by interfacial water molecules. (wikipedia.org)
Such indirect bonds can contribute to the phenomenon of cross-reactivity, i.e. the recognition of different but related antigens by a single antibody. (wikipedia.org)
Antigen and antibody interact through a high affinity binding much like lock and key. (wikipedia.org)
However, these equations are applicable only to a single epitope binding, i.e. one antigen on one antibody. (wikipedia.org)
Not surprisingly, blood type A individuals have the least aggressive antibody immune response against the T and probably Tn antigens. (dadamo.com)
So the hypothesis goes that because of the lower level of antibody against T and Tn antigens or stumps, and because of this tendency for the immune system of A's to be a bit confused or disinclined to attack Tn antigens, blood type A is at an immunologic disadvantage in attacking any cell bearing these T and Tn antigenic markers. (dadamo.com)
In response to this trigger, the body starts making a type of protein called IgE or immunoglobulin E. IgE molecules bind with the allergen molecules in an antigen-antibody reaction. (onteenstoday.com)
IgE molecules bind with the allergen molecules in an antigen-antibody reaction. (onteenstoday.com)
This attachment of the antigen and antibody leads to the release of some chemicals (such as histamine) in the body. (onteenstoday.com)
The antibody recognizes a unique molecule of the pathogen, called an antigen . (wikipedia.org)
[2] [3] Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. (wikipedia.org)
To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. (wikipedia.org)
The class hence determines the function triggered by an antibody after binding to an antigen, in addition to some structural features. (wikipedia.org)
Structurally an antibody is also partitioned into two antigen-binding fragments (Fab), containing one V L , V H , C L , and C H 1 domain each, as well as the crystallisable fragment (Fc), forming the trunk of the Y shape. (wikipedia.org)
This L161 monoclonal antibody detects CD1c, a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. (fishersci.com)
Humoral immunity begins when an antibody on a B cell binds to an antigen. (khanacademy.org)
The GL7 antigen has an epitope containing non-sulfated α2-6-sialyl-LacNAc recognized by the GL7 antibody. (biolegend.com)
GL7 high-expressing B cells show higher antibody production and antigen presenting capacity. (biolegend.com)
Independent of antibody secretion B cells secrete proinflammatory cytokines, support the formation of ectopic GCs, and serve as antigen presenting cells. (hindawi.com)
Left panel: antigen bound by antibody is taken up via FcR on APCs such as dendritic cells or macrophages. (hindawi.com)
Likewise, antigen/antibody complexes are bound by the FcR of APCs and processed in a unique fashion dependent on the epitope specificity of the bound antibody. (hindawi.com)

Glioblastoma multiforme (GBM) evades immune surveillance by inducing immunosuppression via receptor-ligand interactions between immune checkpoint molecules. (medscimonit.com)
About 40% of those receptor molecules bear endoglycosidase H sensitive glycans responsible of the lectin binding activity. (nih.gov)
These CTLs express predominantly two T cell antigen receptor alpha variable gene segments (AV6.1 and AV6.6). (ox.ac.uk)
T cell antigen receptor recognition of MHC molecules independently of bound ligand has potential general implications in alloreactivity and identifies in the Hfe case a cognitive link supporting the concept that the immune system could be involved in the control of iron metabolism. (ox.ac.uk)
The present study was designed to test the hypothesis that signals delivered via the B cell antigen (Ag) receptor (membrane immunoglobulin, mIg) and major histocompatibility complex (MHC) class II molecules enhance B cell responsiveness to CD40‐mediated signals, providing specificity to the Ag‐nonspecific, MHC‐unrestricted CD40 signal. (uthscsa.edu)
Toll-like receptor (TLR) and CD40 signaling in T cells can improve persistence and drive proliferation of antigen-specific CD4 + and CD8 + T cells following pathogen challenge or in graft-versus-host disease (GvHD) settings, suggesting that these costimulatory pathways may be co-opted to improve CAR-T cell persistence and function. (houstonmethodist.org)
The protein intercellular adhesion molecule 3 (ICAM-3) functions as a receptor for LFA-1 (leukocyte function-associated antigen-1) and mediates adhesive interactions of leukocyte cell surface adhesion molecules in inflammatory and immune response. (sigmaaldrich.com)
In 2009, we had a seminal moment when you published a manuscript in The New England Journal of Medicine describing PLA2R, phospholipase A2 receptor, as the antigen that was responsible for a majority of the cases of MN. (medscape.com)
The interaction between the T cell receptor (TCR) and the antigen-presenting major histocompatibility complex (pMHC) on a contacting T cell and APC, is widely accepted to be the key interaction. (lu.se)

Many malignant cells (such as those found in breast and stomach cancer) develop a tumor marker called the Thomsen-Friedenreich (T) antigen. (dadamo.com)
This antigen is suppressed in normal healthy cells, much like a rock is covered over by water at high tide. (dadamo.com)
Healthy cells do not normally express the T or Tn antigen, which are 'encrypted' or covered up by polysaccharides much the same way that a rock is covered by water at high tide. (dadamo.com)
In malignant or pre-malignant cells, the ability to synthesize the polysaccharides which normally cover the T antigen is often lost, which causes T to be 'expressed' or uncovered, much like a falling tide will often uncover previously hidden rocks at a low tide. (dadamo.com)
In this example, the T and Tn antigens are the stumps found in cancer, while the well-groomed yard has bushes, shrubs, and flowers, that correspond to the ABO markers and other antigens found on healthy cells. (dadamo.com)
One of the functions of these T and Tn antigens is to promote cancer cell adhesion----the ability for the cancer cell to stick to other cells including healthy cells. (dadamo.com)
It is now well demonstrated that the repertoire of T cells includes not only cells that recognize specific MHC-presented peptide antigens, but also cells that recognize specific self and foreign lipid antigens. (elsevierpure.com)
These are specialized antigen-presenting molecules that directly bind a wide variety of lipids and present them for T cell recognition at the surface of antigen-presenting cells. (elsevierpure.com)
Here we review the current knowledge of the biology of the CD1 system, including the structure, biosynthesis and trafficking of CD1 molecules, the structures of defined lipid antigens and the types of functional responses mediated by T cells specific for CD1-presented lipids. (elsevierpure.com)
Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function. (ox.ac.uk)
Thus, to address the question of whether alphabeta T cells could recognize MHC molecules independently of bound ligands, we studied human and mouse Hfe interactions with T lymphocytes. (ox.ac.uk)
Dendritic cells (DCs) are specialized antigen presentation cells that play critical roles in the initiation and regulation of immune responses. (biotechnologyconsultinggroup.com)
The 10D1 Ag is a 90-kDa homodimeric molecule specifically expressed on a subpopulation of human T cells, and is involved in an alternative pathway of T cell activation. (aai.org)
Human CD50 is an adhesion molecule that interacts with LFA-1 (CD18/CD11a) and provides a costimulatory signal for T cells which is thought to be essential for initiation of immune responses. (biosave.com)
Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells. (bepress.com)
Analyses of CD8+ TIL show increases in tumor-antigen reactive, proliferating CD103+ CD39+ cells in 25% of patients with evaluable tumor tissue (N = 4/16), all of whom remain disease-free. (bepress.com)
This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. (fishersci.com)
CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. (fishersci.com)
This association afforded us a unique opportunity to identify a sarcoidosis-specific antigen recognized by AV2S3+ T cells. (jci.org)
To identify candidates for the postulated sarcoidosis-specific antigen, lung cells from 16 HLA-DRB1*0301pos patients were obtained by bronchoalveolar lavage. (jci.org)
peptides bound to HLA-DR17 from bronchoalveolar lavage cells of sarcoidosis patients were analyzed in order to identify target antigens of the autoimmune response (see the related article beginning on page 3576). (jci.org)
The GL7 antigen is expressed by pre-B and immature B cells, activated T and B cells, and about 20% of TCR-bright thymocytes. (biolegend.com)
The student will learn about the different organs, cells and molecules and how these work and collaborate, and how cells and functions are regulated and stimulated. (uib.no)
Likewise B cells function as crucial antigen presenting cells in autoimmune diseases that are traditionally viewed as T cell mediated. (hindawi.com)
Both secreted autoantibodies and BCR on B cells can modulate the processing and presentation of antigen and thereby affect the nature of presented T-cell determinants. (hindawi.com)
Right panel: antigen binds to the BCR of antigen-specific B cells and is internalized. (hindawi.com)
B cells are highly efficient APCs in situations of low antigen concentrations. (hindawi.com)
Some, called human leukocyte antigens (HLA), tag your cells so your body can ID itself. (webmd.com)
When these cells find certain antigens (typically, harmless things that your body sees as a threat), they release histamine to bring immune cells to the area. (webmd.com)
Usually, another immune cell, like a dendritic cell, will need to break down an antigen so it can be recognized to start the process of making specialized T cells. (webmd.com)
The roles of the M cells include absorption, transport, processing, and presentation of antigens to subepithelial lymphoid cells. (medscape.com)
the latter are antigen-presenting cells (APCs) that function as memory cells interacting with type 1 THCs. (medscape.com)
M cells in the intestinal epithelium overlying Peyer patches allow transport of antigens to the lymphoid tissue beneath it. (medscape.com)
In this study, we found that cross-presentation of tumor antigen by tumor endothelial cells(tECs) promotes infiltration of tumor specific CTLs in tumors. (nii.ac.jp)
Decreased antigen presentation contributes to the ability of cancer cells to evade the immune system. (lu.se)
We used the minimal gene regulatory network of type 1 conventional dendritic cells (cDC1) to reprogram cancer cells into professional antigen-presenting cells (tumor-APCs). (lu.se)
Reprogramming restored the expression of antigen presentation complexes and costimulatory molecules on the surfaces of tumor cells, allowing the. (lu.se)
Human primary tumor cells could also be reprogrammed to increase their capability to present antigen and to activate patient-specific tumor-infiltrating lymphocytes. (lu.se)
Our approach serves as a platform for the development of immunotherapies that endow cancer cells with the capability to process and present endogenous tumor antigens. (lu.se)
Reprogramming cancer cells to antigen-presenting cells. (lu.se)
It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. (bvsalud.org)
Interactions between immune cells such as T cells and antigen-presenting cells (APCs) are integral for mounting an adaptive immune response. (lu.se)

Protective antigen (PA) is the central component of the three-part protein toxin secreted by Bacillus anthracis, the organism responsible for anthrax. (rcsb.org)
The GL7 antigen, also known as Ly77, is a 35 kD protein. (biolegend.com)

Targeting alternative pathways, such as costimulatory molecules (e.g. (bepress.com)
Stimulation of CD28 on type 1 THCs by B7 costimulatory molecules results in the secretion of interleukin (IL)-2 and interferon gamma by type 1 THCs. (medscape.com)

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule. (bvsalud.org)
However, the diversity and mode of peptide presentation by the HLA-C *0602 molecule remains unclear. (bvsalud.org)
Crystallographic analysis of human Hfe has documented an overall structure similar to classical (class Ia) MHC molecules with a peptide binding groove deprived of ligand. (ox.ac.uk)
Molecules are arranged in the IS in a micrometer scale bull's eye pattern with a central accumulation of TCR/peptide-MHC (the cSMAC) surrounded by a peripheral ring of adhesion molecules (the pSMAC). (ox.ac.uk)
We propose that MHC class I molecules consider initially a large peptide pool, subsequently refined by a temperature-sensitive induced-fit mechanism to retain the canonical peptide repertoire. (nki.nl)
Although a limited number of immunodominant peptide epitopes are consistently observed in diseases such as HIV-1 infection, the relationship between immunodominance and antigen processing in humans is largely unknown. (jci.org)

Intercellular Adhesion Molecule-3 (ICAM-3) is a member of the immunoglobulin supergene family and functions as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1). (biovendor.com)
The gene ICAM3 (intercellular adhesion molecule 3) encodes type I membrane glycoprotein that belongs to the immunoglobulin (ig) superfamily. (sigmaaldrich.com)

Megalin was the rat antigen, which rats have in their glomerulus, but humans don't. (medscape.com)
Seems like quite a daunting project, given that we had been searching for the antigen in humans for so long. (medscape.com)

The crystal structures of the glycosylated N-terminal two domains of ICAM-1 and ICAM-2 provided a framework for understanding the role of glycosylation in the structure and function of intercellular adhesion molecules (ICAMs). (nih.gov)
The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)-1 and ICAM-3 in hydrodynamic flow. (ox.ac.uk)
The I domain of lymphocyte function-associated antigen (LFA)-1 contains an intercellular adhesion molecule (ICAM)-1 and ICAM-3 binding site, but the relationship of this site to regulated adhesion is unknown. (ox.ac.uk)

T and Tn pancarcinoma markers: autoantigenic adhesion molecules in pathogenesis, prebiopsy carcinoma-detection, and long-term breast carcinoma immunotherapy. (dadamo.com)
Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. (cusabio.cn)
In the final part of the thesis, the interaction of TCR-pMHC in the presence of adhesion molecules of different length and density is studied. (lu.se)
To better understand how, and if, adhesion molecules of different lengths influences TCR-pMHC binding the 2D Kd of TCR-pMHC in the presence of differently-sized adhesion molecules was studied. (lu.se)
In addition, the TCR-pMHC distributed non-homogeneously in the cell-SLB contacts when having height-mismatched adhesion molecules, but homogeneously when having height-matched adhesion molecules. (lu.se)
Furthermore, even for height-matched adhesion molecules the 2D Kd of the TCR-pMHC interaction was found to be dependent on the relative density fraction of TCR to adhesion molecules, with low fractions of TCR molecules giving 2-3 times weaker binding. (lu.se)

This T cell recognition of lipid antigens is mediated by a family of conserved MHC class I-like cell surface glycoproteins known as CD1 molecules. (elsevierpure.com)
Furthermore, direct recognition of mouse Hfe molecules by cytotoxic T lymphocytes (CTLs) was demonstrated in DBA/2 Hfe knockout mice. (ox.ac.uk)
Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition. (ox.ac.uk)
T cell antigen recognition is accompanied by cytoskeletal polarization towards the APC and large-scale redistribution of cell surface molecules into 'supramolecular activation clusters' (SMACs), forming an organized contact interface termed the 'immunological synapse' (IS). (ox.ac.uk)
Importantly, the concurrent activation of iMC (with rimiducid) and CAR (by antigen recognition) is required for interleukin (IL)-2 production and robust CAR-T cell expansion and may provide a user-controlled mechanism to amplify CAR-T cell levels in vivo and augment anti-tumor efficacy. (houstonmethodist.org)
MHC class I molecules present a variable but limited repertoire of antigenic peptides for T-cell recognition. (nki.nl)
We developed in vivo method to evaluate the infiltration of tumor specific CTLs in tumors by recognition of tumor antigen on tECs. (nii.ac.jp)

In fact, the T and Tn antigens, and blood type A antigens are actually immunologically considered to be quite similar because of their shared terminal sugar (N-acetylgalactosamine), and so might be readily confused by the immune system of blood type A individuals. (dadamo.com)
These elements of vaccines, and other molecules and micro-organisms that stimulate the immune system, are called "antigens. (cdc.gov)
When a baby is born, his or her immune system is ready to respond to the many antigens in the environment and the selected antigens in vaccines. (cdc.gov)
In fact, a 1994 report from the Institute of Medicine, Adverse Events Associated with Childhood Vaccines external icon , states: "In the face of these normal events, it seems unlikely that the number of separate antigens contained in childhood vaccines …would represent an appreciable added burden on the immune system that would be immunosuppressive. (cdc.gov)
Antigens are any substances that the immune system can recognize and that can thus stimulate an immune response. (msdmanuals.com)

Bricard, G & Porcelli, SA 2007, ' Antigen presentation by CD1 molecules and the generation of lipid-specific T cell immunity ', Cellular and Molecular Life Sciences , vol. 64, no. 14, pp. 1824-1840. (elsevierpure.com)
The saga of MHC-bound peptides: a renaissance for antigen presentation? (jci.org)
In addition to acquiring improved antigen presentation, tumor-APCs had impaired tumorigenicity in vitro and in vivo. (lu.se)

Immunity developed as an individual is exposed to antigens is called adaptive or acquired immunity, in contrast to immunity developed at birth, which is innate immunity. (wikipedia.org)

Hirohashi S. Tumor-associated carbohydrate antigens related to blood group carbohydrates. (dadamo.com)
The goal of this research was to identify specific PDEF induced molecules that, like PDEF, show overexpression in breast tumors and a role in breast tumor progression. (elsevierpure.com)

Autoantibodies can bind to basic structural molecules and interfere with the synthesis of structural elements and facilitate the uptake of antigen. (hindawi.com)
and that tightly bind to the antigen of an invader, tagging the invader for attack or directly neutralizing it. (msdmanuals.com)

Antigens can be bacteria, viruses, or fungi that cause infection and disease. (onteenstoday.com)
such as bacteria, viruses, and yeast) that have sugar molecules attached to their surface (glycan antigens). (medlineplus.gov)

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) has been recently identified as a heterophilic ligand for Tim-3. (medscimonit.com)

Antigens are usually found on the surface of pathogens and are unique to that particular pathogen. (khanacademy.org)

Click molecule labels to explore molecular sequence information. (nih.gov)

Expression and function of a 90-kilodalton homodimeric molecule (10D1 antigen) on human thymocytes. (aai.org)

La interacción de CD86 con el ANTÍGENO CD28 proporciona una señal coestimuladora a los LINFOCITOS T, mientras que la interacción con el ANTÍGENO CTLA-4 puede desempeñar un papel en la inducción de la TOLERANCIA PERIFÉRICA. (bvsalud.org)
The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE. (bvsalud.org)

HLA-DR molecules were affinity purified and bound peptides acid eluted. (jci.org)

Recognizes the D1 domain of the ICAM-3 molecule of 130kD. (biosave.com)

Adhesion molecule pairs of similar height as TCR-pMHC have been argued to facilitate the TCR-pMHC interaction by physically keeping the opposing membranes at an optimal distance for binding. (lu.se)
It was found that the 2D Kd of the TCR-pMHC interaction could be up to an order of magnitude higher (weaker) than the corresponding value for TCR-pMHC alone when having height-mismatched molecules. (lu.se)

Experiments with soluble molecules having the N-terminal two domains of human ICAMs identified glycans of the high mannose type N-linked to the second domain of the dendritic cell-specific ICAM-grabbing nonintegrin lectin-ligands ICAM-2 and ICAM-3. (nih.gov)

We propose that segregation of cell surface molecules on a much smaller scale initiates TCR triggering, which drives the formation of the IS by active transport processes. (ox.ac.uk)

The Thomsen-Friedenreich (T) antigen and Tn antigen show some structural similarity to the A antigen (even though it is derived from the M blood type antigen). (dadamo.com)

What antigen triggers an allergic reaction? (onteenstoday.com)
What kind of antigen can cause an allergic reaction? (onteenstoday.com)
How does an IgE molecule cause an allergic reaction? (onteenstoday.com)

Human leukocyte antigen (HLA)-G and cervical cancer immunoediting: A candidate molecule for therapeutic intervention and prognostic biomarker? (northwestern.edu)
Based on its pronounced immunoinhibitory properties, human leukocyte antigen (HLA)-G has been proposed as a possible prognostic biomarker and therapeutic target relevant in a wide variety of cancers and viral infections, but to date remains underexplored in cervical cancer. (northwestern.edu)
Dive into the research topics of 'Human leukocyte antigen (HLA)-G and cervical cancer immunoediting: A candidate molecule for therapeutic intervention and prognostic biomarker? (northwestern.edu)
Human leukocyte antigen (HLA)-C*0602 is identified as the allele associated with the highest risk for the development of the autoimmune skin disease psoriasis . (bvsalud.org)

The B cell then internalizes the antigen and presents it to a specialized helper T cell, which in turn activates the B cell. (khanacademy.org)

Anatomy19

Organisms34

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Chemicals and Drugs122

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Phenomena and Processes45

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Antibody29

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Cells42

Protein2

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Adhesion molecules6

Recognition7

Immune system5

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