Cell ProliferationCell DivisionSignal TransductionCells, CulturedCell Line, TumorApoptosisCell DifferentiationCell CycleRNA, MessengerGene Expression ProfilingCell MovementImmunohistochemistryReverse Transcriptase Polymerase Chain ReactionMice, Inbred C57BLCell SurvivalGene Expression RegulationBromodeoxyuridineBlotting, WesternCell LineGene Expression Regulation, NeoplasticPhosphorylationMice, KnockoutRNA, Small InterferingTranscription FactorsDown-RegulationLymphocyte ActivationMice, TransgenicTumor Cells, CulturedOligonucleotide Array Sequence AnalysisGene ExpressionProliferating Cell Nuclear AntigenGene Expression Regulation, DevelopmentalCell Growth ProcessesEpithelial CellsUp-RegulationKi-67 AntigenModels, BiologicalStem CellsTransfectionMutationRNA InterferenceTime FactorsDose-Response Relationship, DrugFlow CytometryCell Transformation, NeoplasticDisease Models, AnimalPhenotypeT-LymphocytesCyclin D1Molecular Sequence DataProto-Oncogene Proteins c-aktMice, NudeFibroblastsNeoplasmsAntineoplastic AgentsDNA-Binding ProteinsGene Knockdown TechniquesMice, Inbred BALB CMuscle, Smooth, VascularThymidineCell Cycle ProteinsEnzyme ActivationBase SequenceProto-Oncogene ProteinsExtracellular Signal-Regulated MAP KinasesEnzyme InhibitorsTumor Suppressor Protein p53DNARats, Sprague-DawleyProtein-Serine-Threonine KinasesCell CountMAP Kinase Signaling SystemMicroRNAsCyclin-Dependent Kinase Inhibitor p27Nuclear Proteinsbeta CateninBreast NeoplasmsTranscription, GeneticProto-Oncogene Proteins c-mycNeovascularization, PathologicCyclin-Dependent Kinase Inhibitor p21Transforming Growth Factor betaCell AdhesionHomeodomain ProteinsTumor Suppressor ProteinsNeoplasm ProteinsHyperplasiaPhosphatidylinositol 3-KinasesReal-Time Polymerase Chain ReactionGrowth InhibitorsTrans-ActivatorsEndothelial CellsIn Situ HybridizationMyocytes, Smooth MuscleMitogen-Activated Protein KinasesMolecular Targeted TherapyMitogensNeoplasm InvasivenessProtein BindingAmino Acid Sequence