• In Escherichia coli, the essential ATPase SecA was found to cotranslationally target a subset of nascent membrane proteins to the SecYEG translocase at the plasma membrane. (nih.gov)
  • It appears that the side effects of ibuprofen overdose are related to changes in the properties of the cell membrane and, subsequently, the function of membrane-anchored target proteins. (iasp-pain.org)
  • In relation to membrane excitability, students should be able to describe in detail: (i) the key governing principles, (ii) the role of ion channels and ion transporter proteins, (iii) the relationship between cellular structure and the function of excitable cells, (iv) the features of the synapse that underpin fast chemical neurotransmission and its modification, and (v) the methods used to analyse or predict cell excitability. (manchester.ac.uk)
  • Hijacking pathogenic membrane proteins to engineer cellular entry: A molecular biophysics approach Invasive pathogenic bacteria feature many cellular niches and life cycles, for which they have developed functions that are potentially attractive in biotechnology and therapeutic delivery applications. (umich.edu)
  • Opacity-associated (Opa) proteins of Neisseria gonorrhoeae and N. meningitides are eight-stranded outer membrane proteins that bind to different host receptors, triggering engulfment of the bacterium. (umich.edu)
  • The existence of over 1000 major lipid types creates enormous chemical diversity, which can have a great impact on how proteins bind to membranes in different parts of the cell. (cam.ac.uk)
  • By recruiting many different proteins, PI3P plays a critical role in a number of membrane-dependent processes, including endosomal membrane trafficking and autophagy. (cam.ac.uk)
  • Molecular characterization of proteins in detergent solutions. (wikidata.org)
  • When forming within cells, many proteins rely on the assistance of molecular protectors, so-called chaperones. (sciencebeta.com)
  • In each cell there are molecular helper proteins called chaperones . (sciencebeta.com)
  • Countless proteins, which transport nutrients and signalling molecules, are embedded in the outer membrane of bacteria. (sciencebeta.com)
  • They play an important role in the correct folding of soluble proteins and furthermore are necessary for the insertion of membrane proteins into the bacterial outer membrane. (sciencebeta.com)
  • Because several organelles in plant and animal cells are of bacterial origin, chaperones also similarly protect their membrane proteins and assist during membrane insertion. (sciencebeta.com)
  • Now, our work has succeeded in demonstrating - for the first time in biological membranes - how chaperones support the membrane proteins that are key to pharmaceutical research. (sciencebeta.com)
  • However, this meant that there was barely any understanding of how proteins fold into a cell's membrane. (sciencebeta.com)
  • The platform may be used for functional investigations of important membrane proteins, as well as investigating lipid bilayers of different composition. (lu.se)
  • Two recent X-ray structures shed new light on the molecular mechanisms by which viral proteins mediate membrane fusion. (princeton.edu)
  • Anti-glomerular basement membrane (anti-GBM) disease is a classic autoimmune disorder characterized by the presence of circulating pathogenic autoantibodies directed against proteins in the glomerular and alveolar basement membranes. (medscape.com)
  • Our main goal is to understand how the molecular properties of proteins and membranes modulate cellular processes. (unifr.ch)
  • The energetics of these remodelling processes are governed by the interplay between specialized proteins and membrane properties, but in most cases, we still lack a detailed molecular explanation of how these processes can be modulated in a cellular environment. (unifr.ch)
  • Interactions between proteins and membranes are a vital part of cell functioning. (unifr.ch)
  • Some proteins only interact with membranes transiently, while others are constantly embedded into the membrane. (unifr.ch)
  • In both cases, however, proteins have been engineered by nature to "sense" their membrane environment and to respond to its variations. (unifr.ch)
  • This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. (nih.gov)
  • Proteins in lipid membranes are one of the fundamental building blocks of biological functionality. (phys.org)
  • More than half of all proteins interact with membranes. (phys.org)
  • Biological membranes consist of a phospholipid bilayer and a variety of proteins that accomplish vital biological functions. (phys.org)
  • Membrane receptor proteins serve as connection between the cell's internal and external environments. (phys.org)
  • Our project offers a unique opportunity for Master's student to gain hands-on experience focused on transcriptional regulators with importance in expression of genes of outer membrane proteins that are essential in host-pathogen interaction. (lu.se)
  • Molecular Membrane Biology is a peer-reviewed scientific journal that publishes review articles of biomembranes at the molecular level. (wikipedia.org)
  • The Molecular Membrane Biology GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. (grc.org)
  • The 2023 Gordon Conference on Molecular Membrane Biology will focus on the latest insights into organelle biogenesis and function, membrane trafficking, the connection to metabolism, and interorganelle communication. (grc.org)
  • The meeting will include sessions on novel techniques and their application in molecular membrane biology, and relevance for diseases. (grc.org)
  • This GRC will be held in conjunction with the "Molecular Membrane Biology" Gordon Research Seminar (GRS). (grc.org)
  • We thank Professor Ramanujan Hegde (MRC Laboratory of Molecular Biology, Cambridge, UK) for the kind gift of anti‐TRAPα antibody and Professor Peter Arvan (University of Michigan Medical School, Ann Arbor, MI, USA) for the kind gift of INS‐1 832/13 cells. (lu.se)
  • Based on application, the track etched membrane market is segmented into cell biology, microbiology, analytical testing, and other applications. (marketsandmarkets.com)
  • Of all these application segments, the cell biology segment is expected to lead track etched membrane market in 2018. (marketsandmarkets.com)
  • Hughson, FM 1995, ' Molecular mechanisms of protein-mediated membrane fusion ', Current Opinion in Structural Biology , vol. 5, no. 4, pp. 507-513. (princeton.edu)
  • This course element will introduce you to the fundamental principles of medically related cell biology and molecular and clinical genetics. (le.ac.uk)
  • There will be involved gene engineering and molecular biology methods such as PCR, SDS-PAGE, qPCR, western blot, DNA-protein interaction assays, flow cytometry etc. (lu.se)
  • Invited talks will feature a broad range of topics including membrane biogenesis, protein sorting to organelles, metabolic regulation of organelle biogenesis, autophagy, protein and organelle quality control, lipid homeostasis, interorganelle contact sites, host-pathogen interactions, and the mechanism of organelle fission and fusion. (grc.org)
  • Cotranslational protein targeting is a conserved process for membrane protein biogenesis. (nih.gov)
  • Over the next five years, our goals are to (1) identify novel recycling receptors required at different Golgi compartments and establish a systematic map of the intra-Golgi recycling network, (2) determine how the transmembrane receptors engage with their cargos, and (3) define the novel functions of a disease-associated membrane transporter in solute transport and protein recycling in the Golgi. (cornell.edu)
  • Protein translocation across the endoplasmic reticulum (ER) membrane is an essential step during protein entry into the secretory pathway. (lu.se)
  • In cells, the majority of Sec61 is stably associated with a heterotetrameric membrane protein complex, the translocon-associated protein complex (TRAP), yet the mechanism by which TRAP assists in polypeptide translocation remains unknown. (lu.se)
  • Roger Williams' group , in the LMB's PNAC Division, has now shown how membrane characteristics can tune the activities of protein complexes that have important roles in autophagy, cell division, and endosomal membrane trafficking. (cam.ac.uk)
  • To investigate how VPS34 activity is affected by different membrane compositions, Yohei Ohashi and Shirley Tremel, two members of Roger's group, assembled the purified protein components of two different VPS34-containing complexes and created a lipid sphere that could be attached to a surface to allow easy monitoring. (cam.ac.uk)
  • With support from the LMB's Light Microscopy and Biophysics facilities and collaborators at the Babraham Institute, Yohei and Shirley were able to observe greater VPS34 activity at highly curved membranes where curvature causes packing defects that allow better protein attachment. (cam.ac.uk)
  • due, again, to packing defects that allow the protein to more easily attach itself to the membrane. (cam.ac.uk)
  • The roles of chaperones in membrane protein folding have long remained unclear. (sciencebeta.com)
  • Researchers at the Biozentrum, University of Basel, and at ETH Zurich have now shown how chaperones stabilize an immature bacterial membrane protein and guide it in the right folding direction, thus protecting it from misfolding. (sciencebeta.com)
  • The scientists, led by Prof. Sebastian Hiller from the Biozentrum, University of Basel, and Prof. Daniel Müller from the Department of Biosystems Science and Engineering (D-BSSE), ETH Zurich in Basel have discovered how two chaperones in the gut bacterium E. coli protect the membrane protein FhuA during transport and assist its insertion into the membrane. (sciencebeta.com)
  • One of these membrane transporters is the protein FhuA. (sciencebeta.com)
  • It thus explores energetically favorable conformations which enable the stepwise insertion and folding of individual protein segments into the membrane. (sciencebeta.com)
  • Here, cryo-EM is used to examine the protein-lipid architecture of this membrane in tubular vesicles obtained from the (muscle-derived) electric organ of the Torpedo ray. (iucr.org)
  • Here, we analyse by cryo-EM the architecture of this membrane in vesicles isolated from the (muscle-derived) electric organ of the Torpedo ray, with view to defining the protein-lipid interplay required to achieve an optimal neurotransmitter response. (iucr.org)
  • 4. Membrane-protein interactions. (unifr.ch)
  • Using a combination of MD simulations and biochemical approaches, we study how membrane properties regulate protein functions, and hence how lipid metabolism may play a role in unexpected, and apparently unrelated, trafficking processes. (unifr.ch)
  • The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. (nih.gov)
  • A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting. (nih.gov)
  • Because most tubulin is not membrane associated, this study investigates whether tubulin translocates to the membrane in response to an agonist so that it might regulate G-protein signaling. (jneurosci.org)
  • A membrane protein is a protein molecule that is attached to, or associated with the membrane of a cell or an organelle. (phys.org)
  • This will allow membranes with tailored properties to be developed for applications in key membrane processes, such as antimicrobial peptide activity, protein interactions, and DNA transfection. (lu.se)
  • Membranes around different subcellular compartments display distinct properties due in part to differential enrichment of different types of lipids. (cam.ac.uk)
  • One determinant of these membrane characteristics is how tightly the lipids are able to pack together. (cam.ac.uk)
  • The lipid kinase VPS34 is an enzyme that, while a component of a number of distinct complexes, works at membranes to modify the headgroup of certain types of lipids to produce an important phospholipid known as PI3P (phosphatidylinositol 3-phosphate). (cam.ac.uk)
  • Currently, the main focus of the lab is to understand how specific lipids and membrane properties influence intracellular trafficking processes and fat storage in eukaryotic cells. (unifr.ch)
  • As such, many biological processes occur within or in the proximity of the cell membrane, and therefore, interest in the properties and behavior of lipids in membranes is considerable. (lu.se)
  • Our hybrid NMR and molecular dynamics structure of an Opa reveals that the variable regions are dynamic and disordered, and sample conformations that may be competent for receptor binding. (umich.edu)
  • In this work, a combination of molecular dynamics (MD) simulations and solid-state NMR was used to present an atomistic model of a polypyridylruthenium(II) complex bound and incorporated into a bacterial membrane model. (ibm.com)
  • In this work, molecular dynamics simulations were applied to observe the influence of membrane cholesterol levels on a voltage-gated sodium channel. (aiche.org)
  • Our main approach is molecular dynamics (MD) simulations. (unifr.ch)
  • Molecular dynamics (MD) simulations indicated that simulated membranes hindered the diffusion of dyes inside layers. (hanyang.ac.kr)
  • Molecular and cellular function of ALS2/alsin: implication of membrane dynamics in neuronal development and degeneration. (medlineplus.gov)
  • Engineering smart materials at a large scale with tunable properties for molecular separation is a challenging step to materialize this goal. (nature.com)
  • A dual function is achieved by combining molecular separation and catalysis. (nature.com)
  • While the membrane promotes a precise molecular separation, its catalytic activity enables surface self-cleaning, by reacting with any potentially adsorbed dye and recovering the original performance. (nature.com)
  • While commercial membranes have excellent performance in the separation of salts from water in large-scale desalination plants, they lack selectivity for molecules of similar size and charge. (nature.com)
  • We also reported smart covalent organic networks (CONs) with light-switchable pores for molecular separation prepared by IP 18 . (nature.com)
  • Smart tuning of the membrane's porous nanostructures offers an effective strategy for creating state-of-the-art, high-performance separation membranes. (aminer.org)
  • Such membranes can be used in a variety of applications such as natural gas processing, air separation, or hydrogen purification. (edu.sa)
  • Next to excellent separation properties, these membranes show promising scale-up potential as they build on common processing techniques used in the membrane fabrication industry today. (edu.sa)
  • This invention comprises novel TFC membranes containing a small molecule pore element separated from a polymeric matrix element, enabling enhanced performance for gaseous, aqueous, organic solvent, and small molecule separation relative to leading membrane technologies. (psu.edu)
  • In order to reach its goal in the outer membrane, FhuA uses the help of several chaperones. (sciencebeta.com)
  • Cholesterol interactions with the receptor are apparently essential for stabilizing and maintaining its physiological architecture, since the transmembrane structure contracts, involving displacements of the helices at the outer membrane surface by ∼2 Å (1-3 Å), when this lipid is extracted. (iucr.org)
  • hence, the activity probably locates on the outer surface of the cell membrane. (nih.gov)
  • Researchers have developed models of bacterial outer membranes that can help develop better antibiotics to fight antibiotic-resistant bacteria. (phys.org)
  • For example, it is found that in nature the lipid distribution across the inner and outer leaflet of cell membranes is asymmetric and this asymmetry plays a prominent role in processes like cell fusion, activation of the coagulation processes and the recognition and removal of apoptotic cells by macrophages. (lu.se)
  • One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health. (cam.ac.uk)
  • Pharmaceutical and biopharmaceutical companies are the largest end-users of track etched membranes majorly due to the growing research towards the development of biological molecules, increasing manufacturing of generic drugs in emerging countries, and stringent regulations imposed by government and regulatory agencies to enhance the quality of pharmaceutical and biopharmaceutical products. (marketsandmarkets.com)
  • Each of our cells is surrounded by a complex membrane that functions as a biological border, letting ions and nutrients such as salt, potassium and sugar in and out. (phys.org)
  • The phospholipid bilayer is the basic structural motif of most biological membranes. (lu.se)
  • This project aims to study the mechanism of formation and structure of complex lipid bilayers, a lipid composition that mimics biological membranes (i.e. composed of several lipid types) on a variety of substrates including structured surfaces consisting of nanowire forests. (lu.se)
  • The channel element is highly uniform and tunable, enabling a solution flow mechanism that enhances solvent permeability while retaining molecular selectivity. (psu.edu)
  • Results showed that composite membranes exhibited both enhanced pure water permeability (PWP) and improved dyes removal capacity. (hanyang.ac.kr)
  • Ribosome interactions anchor the Sec61/TRAP complex in a conformation that renders the ER membrane locally thinner by significantly curving its lumenal leaflet. (lu.se)
  • However, the molecular interactions between ibuprofen and the cell membrane are not well understood. (iasp-pain.org)
  • In this study, we have analyzed the interactions of the lead compound SS-31 (Elamipretide) with model and mitochondrial membranes using biophysical and computational approaches. (biorxiv.org)
  • Their potency and uptake into bacterial cells is directly modulated by the length of the bridging linker, which has implicated membrane interactions as an essential feature of their mechanism of action. (ibm.com)
  • Although the basement membrane (BM) is located at tissue interfaces, its mode of action in inter-tissue interactions remains poorly understood, mainly because the molecular and structural details of the BM at distinct inter-tissue interfaces remain unclear. (biorxiv.org)
  • By combining quantitative transcriptomics and immunohistochemistry, we systematically identify the cellular origin, molecular identity and tissue distribution of extracellular matrix molecules in mouse hair follicles, and reveal that BM composition and architecture are exquisitely specialized for distinct inter-tissue interactions, including epidermal-fibroblast, epidermal-muscle and epidermal-nerve interactions. (biorxiv.org)
  • We will investigate the use of nano-wire "forests" developed by Lars Samuelson's group at Solid State Physics, Lund University as a support for free standing lipid bilayers and means to sense membrane mechanical properties, such as lateral stress, as well as biomolecular interactions and activity with and in the membrane. (lu.se)
  • This paper reports on the performance of polysulfone (PSf)/polyetherimide (PEI) ultrafiltration (UF) composite membranes coated on polyester (PE) support by spin/spray-coating technique to remove reactive blue 171 (RB171) and Basic Red 1 (BR1) from water. (hanyang.ac.kr)
  • 1. Method development in molecular simulations. (unifr.ch)
  • By combining coarse grain MD simulations and biochemical and cellular experiments, we investigate how membrane properties modulate remodelling processes and how this might influence cell functioning. (unifr.ch)
  • A transbilayer mechanism and membrane-spanning may be essential for the cellular uptake and antibacterial activity of this class of compounds. (ibm.com)
  • This course element will cover the medically and clinically related fundamental principles of cellular and molecular physiology that form the basis for the understanding of pharmacology (use of drugs to treat human disease). (le.ac.uk)
  • Other procedures can be executed aiming to increase the bone volume, such as osteogenic distraction (surgical induction of the bone fracture and splitting into two fragments so that a new bone is formed between them), osteoinduction with growth factors and/or stem cells, osteoconduction by the use of substrates for cellular development (scaffolds) and guided tissue regeneration (GTR) with the aid of membranes 18 . (bvsalud.org)
  • At this concentration, the physical and structural properties of the cell membrane change significantly. (iasp-pain.org)
  • The three-step interaction between ibuprofen and the lipid bilayer involves several events, such as the movement of ibuprofen molecules towards the central region of the lipid bilayer and the deformation and alteration of the structural and stability properties of the cell membrane. (iasp-pain.org)
  • Ultrathin crosslinked polycage selective layers (thickness as low as 9.5 nm) are obtained with high permeance and strict molecular sieving for nanofiltration. (nature.com)
  • In aqueous solution, polyethylene glycol (PEG) grafted boron nitride PEGX-g-(f-BN) nanosheets exhibit high permeance and excellent molecular sieving. (aminer.org)
  • PEGX-g-(f-BN) lamellar membranes show unprecedented permeance of ∼1253 L m−2 h−1 bar−1 with a steady methyl blue (MB) exclusion of 98.9% even in different pH conditions. (aminer.org)
  • The TFC membrane exhibits over twice the permeance of leading membrane technologies with comparable selectivity. (psu.edu)
  • North America is estimated to hold the largest share of the track etched membrane market in 2018, followed by Europe and Asia Pacific. (marketsandmarkets.com)
  • The selectivity of the membrane will dictate the number of steps required for an effective process. (nature.com)
  • The molecular selectivity of the PEGX-g-(f-BN) lamellar membrane is controlled by the nanopores, which can be tuned by modulating the interplanar spacing between the nanosheets. (aminer.org)
  • Preliminary membrane test results show selectivity performance around ~70 to ~300, indicating impactful savings in industrial processes (compared to conventional distillation processes). (psu.edu)
  • The aim of this module is to give students the strongest grounding in our current understanding of excitable cell pharmacology and physiology through study of the key elements of membrane excitability. (manchester.ac.uk)
  • Thank you for sharing this Molecular Pharmacology article. (aspetjournals.org)
  • Message Body (Your Name) thought you would be interested in this article in Molecular Pharmacology. (aspetjournals.org)
  • Polyimides of intrinsic microporosity (PIM-PIs) are a subclass of polymers of intrinsic microporosity (PIMs) which can serve as excellent precursors for high-efficiency carbon membranes for molecular separations. (edu.sa)
  • Concentration-dependent mechanism of the binding behavior of ibuprofen to the cell membrane: A molecular dynamic simulation study. (iasp-pain.org)
  • In addition, our findings indicate that at low concentrations of ibuprofen, these molecules did not significantly alter the physical properties of the cell membrane. (iasp-pain.org)
  • When the nuclear membrane goes from a large single structure into many smaller subunits, so it can disperse, the effect is due to surface tension with the nucleus of the cell. (scienceforums.net)
  • Studies on the major sialoglycoprotein of the human red cell membrane. (wikidata.org)
  • Red cell membranes: fact and fancy. (wikidata.org)
  • We now have a better understanding of how the cell incorporates its molecular machines into membranes so that they can perform their versatile duties. (sciencebeta.com)
  • The prepared chitin/gelatin membranes with or without GlcNAc were characterized by mechanical, swelling, enzymatic degradation, thermal and growth of NIH/3T3 fibroblast cell studies. (amrita.edu)
  • Cell membranes are continually remodelled to achieve communication between intracellular compartments and to selectively exchange materials between them. (unifr.ch)
  • Transforming growth factor-alpha (TGF-alpha) is synthesized and transported to the cell surface as a membrane-anchored precursor (proTGF-alpha) that is converted to the soluble form by proteolytic cleavage. (nih.gov)
  • In the cell-free reconstitution system, the membrane-bound Suc-Ala-Ala-Ala-MCA-hydrolyzing enzyme from CHO cells was also activated by phorbol ester in the presence of the soluble fraction, ATP, and vanadate. (nih.gov)
  • In SK-N-SH cells, carbachol induced a rapid and transient translocation of tubulin to the plasma membrane, microtubule reorganization, and a change in cell shape as demonstrated by confocal immunofluorescence microscopy. (jneurosci.org)
  • Membrane enzymes produce a variety of substances essential for cell function. (phys.org)
  • Szeto-Schiller (SS) peptides comprise a class of amphipathic tetrapeptides that have demonstrated efficacy in treating a wide array of mitochondrial disorders, and are believed to target mitochondrial membranes due to their enrichment in the anionic phospholipid cardiolipin (CL). (biorxiv.org)
  • Most notably, SS-31 modulates the surface electrostatic properties of model and mitochondrial membranes, which could play a significant role in the mitoprotective properties of this compound. (biorxiv.org)
  • As a proof of concept, we show that SS-31 alters ion distribution at the membrane interface with implications for maintaining mitochondrial membranes subject to divalent cation (calcium) stress. (biorxiv.org)
  • Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise -induced hearing loss in mice. (cdc.gov)
  • Mice homozygous for a null mutation in the plasma membrane Ca2+-ATPase isoform 2 (PMCA2) gene are deaf (Kozel et al. (cdc.gov)
  • Those changes within the nuclear membrane are equilibrium phenomena connected to hydrogen bonding potential. (scienceforums.net)
  • Lipid membranes surround our cells and form the boundaries around compartments within them. (cam.ac.uk)
  • 3. Membrane remodelling processes. (unifr.ch)
  • The area includes projects focused on the study of respiratory chain NADH:quinone oxidoreductase ( Complex I ), aquaporin membrane water channels and a technology platform for monitoring trans-membrane proton flux . (lu.se)
  • The results of 31P, 2H, 1H, and 13C NMR studies revealed that the antibacterial [{Ru(phen)2}2(μ-bb12)]4+ complex (Rubb12), where phen = 1,10-phenanthroline and bb12 = bis[4(4′-methyl-2,2′-bipyridyl)]-1,12-dodecane), incorporated into a negatively charged model bacterial membrane, but only associated with the surface of a charge-neutral model of a eukaryotic membrane. (ibm.com)
  • Exposure to temperatures above 400 °C under an inert atmosphere leads to profound chemical and morphological transformation of the organic polymer precursor into amorphous, microporous carbon molecular sieve (CMS) structures. (edu.sa)
  • His current research activities deal with thin and ultra-thin composite membranes comprising amorphous microporous materials, such as polymers of intrinsic microporosity and carbon molecular sieves. (edu.sa)
  • The syndrome was subsequently shown to be caused by an antibody response against antigens present in the alveolar and glomerular basement membranes. (medscape.com)
  • it is found only in a few specialized basement membranes, including the glomerular and alveolar basement membranes. (medscape.com)
  • Herein, we report thin film composite membranes prepared by the interfacial polymerization of porous organic cages (POCs) (RCC3 and tren cages). (nature.com)
  • Our results show that this polybasic peptide partitions into the membrane interfacial region with affinity and binding density that are directly related to surface charge. (biorxiv.org)
  • The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic. (nih.gov)
  • Finally, we show that membrane-embedded SecYEG promotes handover of the translating ribosome from SecA to the translocase via a concerted mechanism. (nih.gov)
  • Morphological characterization by SEM showed homogeneous and uniform distribution of PSf/PEI membrane layer on the polyester support. (hanyang.ac.kr)
  • In addition, students will be encouraged to think critically and to appreciate the special challenges intrinsic to studying excitable membrane function. (manchester.ac.uk)
  • Simulation of excitable membrane behaviour to expand understanding of the Nernst equation and the ionic basis for excitability. (manchester.ac.uk)
  • The postsynaptic membrane, apposing the pre-synaptic nerve terminal, is where transmitter-gated ion channels are concentrated. (iucr.org)
  • Molecular tests were used to detect pathogens. (who.int)
  • A key factor for the practical production of thin-film composite (TFC) membranes is the reaction time. (nature.com)
  • Prepared composite membranes with polysulfone (PSf) and different PEI loading (25 wt% (CM25), 30 wt% (CM30), and 35wt% (CM35)) were initially characterized in terms of morphological, mechanical, wetting and water transport properties. (hanyang.ac.kr)
  • The composite membranes CM35 showed a PWP of 77.42 L/hm(2)bar, and rejection rates of 93.8% and 78.9% for RB171 and BR1, respectively. (hanyang.ac.kr)
  • PLGA membranes were hourglass-shape cut and prepared at three different conditions of temperature and humidity (n = 10): (I) dry membrane at environment temperature of about 20ºC (control group), (II) moist membrane plasticized at 55ºC, (III) moist membrane plasticized at 55ºC, which subsequently underwent cooling. (bvsalud.org)
  • Subsequently, the membranes were subjected to tensile tests in a universal testing machine (DL-2000, EMIC) at 1.0 mm/min. (bvsalud.org)