Molecular gene expression regulation bacterial. Medical search. Frequent questions

Regulation of gene expression by proteins and small RNAs. (otago.ac.nz)
The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. (cipsm.de)
Plastid-specific ribosomal proteins (PSRPs) have been proposed to play roles in the light-dependent regulation of chloroplast translation. (cipsm.de)
We show here that six genes (bus-2, bus-4, and bus-12, together with the previously cloned srf-3, bus-8, and bus-17) encode proteins predicted to act in surface glycosylation, thereby affecting disease susceptibility, locomotory competence, and sexual recognition. (ox.ac.uk)
Numerous fundamental cellular processes, including virtually every aspect of gene expression and regulation, depend on the cooperation of RNAs and proteins. (fu-berlin.de)
Specific RNAs and proteins associate to build up some of the most complex macromolecular machineries of living cells, such as ribosomes and spliceosomes, which mediate particular steps of gene expression. (fu-berlin.de)
RNAs and proteins can also engage in more transient interactions, for example during co-transcriptional regulation of RNA polymerases or during post-transcriptional regulation of (pre-)mRNA life cycles. (fu-berlin.de)
We investigate the molecular mechanisms, by which RNAs and proteins cooperate to bring about the biological functions of selected RNPs involved in transcription and pre-mRNA splicing. (fu-berlin.de)
Our project offers a unique opportunity for Master's student to gain hands-on experience focused on transcriptional regulators with importance in expression of genes of outer membrane proteins that are essential in host-pathogen interaction. (lu.se)
Researchers can now provide a picture of how proteins regulate genetic expression at the atomic level. (sciencedaily.com)
Genes can be regarded as blueprints for all of the molecular machines -normally proteins-that perform the tasks an organism needs for survival. (sciencedaily.com)
This is done through regulation of the activity of proteins that already exist in the cell, but also by the binding of special proteins-transcription factors-to specific sites on the DNA, turning certain genes on or off, which in turn regulates the cell's production of various proteins. (sciencedaily.com)
Despite its small genome and limited number of effector proteins, Ehrlichia efficiently establishes an intracellular infection and avoids immune defenses in vertebrate and invertebrate hosts through complex molecular and cellular reprogramming strategies. (frontiersin.org)
The course comprises molecular biology of genes, proteins, multicomponent protein complexes, and other biomolecules that provide structure and perform the organism's functions. (lu.se)
DnaK is a bacterial chaperone protein that recognizes misfolded and aggregated proteins and drives their folding and intracellular trafficking. (bvsalud.org)
The main aim of our research is to understand the molecular details and physiological roles of the multitude of water channel-like proteins present in plants and animals. (lu.se)

Reading through each chapter, the reader can follow along with a sort of classical genetics take on molecular biology. (cdc.gov)
The Plant Biotechnolog y specialization uses the tools of molecular biology, genetics, and tissue culture to learn how plant cells work and to develop plants with improved traits. (hawaii.edu)
The Department of Biochemistry and Molecular Biology offers a program leading to the Doctor of Philosophy degree. (nymc.edu)
The objective of this program is to provide students with a thorough background in modern biochemistry and molecular biology. (nymc.edu)
Research opportunities in the department are in the areas of protein structure and function, enzyme reaction mechanisms, regulation of gene expression, mechanism of hormone action and cell signaling, enzymology and mechanisms of DNA replication and repair, cell cycle regulation, control of cell growth, molecular biology of the cancer process, molecular neurobiology, and the genetics and biochemistry of bacterial and viral pathogens. (nymc.edu)
2001-2004 Ph.D. (Molecular Biology). (ncl.ac.uk)
The lecture series is a joint activity of the chairs of Cell- and Developmental Biology, Microbiology, Biophysics and Bioinformatics and deals with concepts of modern molecular biology from the point of view of these different disciplines. (uni-wuerzburg.de)
The section Cell Biology mainly regards the eukaryotic cell and intends to elucidate the vast diversity in structure and function of molecules, organelles and cells in addition to basic principles of modern molecular cell biology. (uni-wuerzburg.de)
The bioinformatics section contains a large amount of examples for applications which allow the investigation of the molecular biology of a cell with bioinformatics tools. (uni-wuerzburg.de)
The topics range from classical developmental subjects such as tissue regeneration and morphogenetic cell migration to molecular stem cell biology, epigenetic plasticity, origins of multicellularity and development within changing environments. (uni-wuerzburg.de)
New Facets in Mycobacterium and Malaria parasite biology, Regulation of gene expression. (infinitecourses.com)
Genetics and Molecular Biology is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. (eolss.net)
The Theme on Genetics and Molecular Biology with contributions from distinguished experts in the field deals with genetics and its development and biology at the Molecular level. (eolss.net)
Master's degree in Agriculture/ Biotechnology/ Molecular Biology & Bio-Technology/ Genetic Engineering/ Botany/ Plant Sciences/ Life Sciences/Plant Physiology with specialization in Plant Biotechnology. (nipaers.com)
Students have the option to choose the Molecular, Cellular, and Developmental Biology (MCD) concentration or the Ecology, Evolution, and Environmental Biology (E3B) concentration but are not required. (charlotte.edu)
Advanced Cellular and Molecular Biology. (charlotte.edu)
A laboratory- oriented course designed to integrate plant molecular biology, recombinant DNA technology, and plant cell and tissue culture. (charlotte.edu)
There will be involved gene engineering and molecular biology methods such as PCR, SDS-PAGE, qPCR, western blot, DNA-protein interaction assays, flow cytometry etc. (lu.se)
To provide students with the opportunity to be exposed to the current state of understanding of the molecular biology of bacteria. (lu.se)
The students will gain an understanding of genetics concepts and molecular biology techniques by using them in the context of a research project. (lu.se)
Molecular Membrane Biology 2013, 30 (3):246-260. (lu.se)

Molecular mechanisms by which bacteria adapt to environmental change. (otago.ac.nz)
MICR 335 will provide a fundamental knowledge of the mechanisms that bacteria use to sense their environment and adapt their gene expression to optimise their growth and survival. (otago.ac.nz)
In addition, the molecular mechanisms connecting dynamic resource allocation to division control in bacteria are not clear, nor is our understanding of how these allocation strategies are affected by the temporal pattern of environmental fluctuations. (nature.com)
Key aspects include the organization of the bacterial genome, the transcription and translation machinery, mechanisms of regulation of gene expression, transport of small molecules and macromolecules, cell division and differentiation, bacterial motility and chemotaxis, signal transduction and bacterial communication mechanisms. (uni-wuerzburg.de)
Regulatory mechanisms for chromosomal genes encoding multidrug resistance (MDR) efflux pumps (EPs) in Staphylococcus aureus are poorly defined. (manchester.ac.uk)
Degradation of toluene and 2-methylnaphthalene, and the presence of at least one bss-like and bbs-like gene cluster in this organism, suggests that NaphS2 degrades both compounds via parallel mechanisms. (elsevierpure.com)
Here we review the different molecular mechanisms by which these signals are integrated and modulate the phosphorylation state of SKs. (nih.gov)
This study also provides a firm basis for future studies to address molecular mechanisms of indirect regulation of gene expression by σS. (hal.science)
Although the overall mechanisms behind gene regulation have long been known, the fine details have eluded scientists for decades. (sciencedaily.com)
In this review, we discuss the recent advances in our understanding of the molecular and cellular mechanisms that underlie Ehrlichia host cellular reprogramming strategies that enable intracellular survival. (frontiersin.org)
The molecular mechanisms involved in the antifungal resistance of biofilms remain poorly understood. (who.int)

The history of Snyder and Champness Molecular Genetics of Bacteria goes back more than 24 years ( Figure ). (cdc.gov)
We observed CsrS-dependent regulation of 72 of the 73 genes whose expression changed in response to elevated extracellular Mg(2+) in wild-type bacteria, a result that identifies CsrS as the principal, if not exclusive, sensor for extracellular Mg(2+) in GAS. (lu.se)
Bacterial genomics, regulation, and resistance - Bacteria are a powerful unicellular model system to investigate the fundamental relation between genomic sequence, gene and protein expression, dynamics of molecular pathways, and resultant phenotypes. (utsouthwestern.edu)
The fundamental principles of molecular circuitry are conserved from bacteria to human cells. (utsouthwestern.edu)
The Green Center brings together both approaches with scientific synergy to apply axioms of molecular circuitry understood through bacteria to cancer metastasis. (utsouthwestern.edu)
We study the functional interplay of pausing, termination and continued transcription, which constitutes a pervasive gene regulatory principle in bacteria. (fu-berlin.de)
In order to react effectively to changes in the surroundings, bacteria must be able to quickly turn specific genes on or off. (sciencedaily.com)
Furthermore, nucleotide sequences related to the cluster vanHAX are present in this DNA, suggesting that the prolonged use of avoparcin in agriculture led to the uptake of glycopeptide resistance genes by animal commensal bacteria, which were subsequently transferred to humans. (cdc.gov)
The realization of the vastness of bacterial diversity and the development of novel experimental techniques have propelled molecular microbiology into a new era of investigation This course provides insights into how genes are organized and regulated in bacteria and in their viruses. (lu.se)
be able to describe molecular genetic processes in bacteria. (lu.se)

Translation inhibition by arrest peptides is critically dependent on their amino acid sequence, but often requires an additional low molecular weight ligand, such as a drug or a metabolite, to be sensed by the ribosome nascent chain complex. (u-bordeaux.fr)

Molecular Microbiology is highly relevant to all aspects of modern microbiology. (otago.ac.nz)
Appropriate for students majoring in Microbiology, Genetics, Biochemistry or Molecular Biotechnology. (otago.ac.nz)
The lecture course is complemented by a laboratory course that aims to help students develop research skills relevant to molecular microbiology. (otago.ac.nz)
to acquire intellectual ability and practical skills to work productively in a commercial setting, institute, or university laboratory on different aspects concerning molecular microbiology. (lu.se)

Students can learn molecular diagnostic methods such as PCR, DNA finger-printing, gene mapping, and protein analysis. (hawaii.edu)
A common theme of the research programs is the application of modern recombinant DNA technology to the study of gene regulation and protein structure-function relationships. (nymc.edu)
To further characterize pathways involved in naphthalene degradation in NaphS2, the draft genome was sequenced, and gene and protein expression examined. (elsevierpure.com)
Genes including the previously characterized NmsA, thought to encode an enzyme necessary for 2-methylnaphthalene metabolism, were not upregulated during growth of NaphS2 on naphthalene, nor were the corresponding protein products. (elsevierpure.com)
The cloning of maize PPDK regulatory protein (PDRP) revealed the regulatory protein had been sequenced from more than 200 bacterial species and had been identified as DUF299 (domain of unknown function). (scirp.org)
We also identified 24 apaQTLs associated with protein levels, but not mRNA expression. (elifesciences.org)
Thus, our work demonstrates that APA links genetic variation to variation in gene expression, protein expression, and disease risk, and reveals uncharted modes of genetic regulation. (elifesciences.org)
Moreover, RNA-protein complexes (RNPs) provide glimpses at the molecular ancestry of modern cells, which most likely evolved from an RNA-dominated world. (fu-berlin.de)
A novel small heat shock protein gene, vis1, contributes to pectin depolymerization and juice viscosity in tomato fruit. (ox.ac.uk)
We have characterized a novel small heat shock protein gene, viscosity 1 (vis1) from tomato (Lycopersicon esculentum) and provide evidence that it plays a role in pectin depolymerization and juice viscosity in ripening fruits. (ox.ac.uk)
vis1 is regulated by fruit ripening and high temperature and exhibits a typical heat shock protein chaperone function when expressed in bacterial cells. (ox.ac.uk)
There, he chose to tackle what was, at the time, a little-known form of translational control: the regulation of ribosomal protein synthesis by the nascent polypeptide. (u-bordeaux.fr)
As part of the process of translation, nascent polypeptides transit through a long molecular cavity spanning the large subunit of the ribosome - known as the exit tunnel -- before they are released into the cytoplasm or delivered to the protein translocation machinery. (u-bordeaux.fr)
This is the first study to show that a bacterial chaperone protein interacts with key eukaryotic components thus suggesting DnaK could become a perturbing hub for the functions of important cellular pathways. (bvsalud.org)

Essentially nothing is known about the signal transduction pathways involved in the observed differential expression of virulence genes. (ed.ac.uk)

Concept of gene, Prokaryotes as genetic system, Prokaryotic and eukaryotic chromosomes, methods of gene isolation and identification, Split genes, overlapping genes and pseudo genes, Organization of prokaryotic and eukaryotic genes and genomes including operan, exon, intron, enhancer promoter sequences and other regulatory elements. (nipaers.com)
Type I toxin-antitoxin (TA) systems are widespread genetic modules in bacterial genomes. (mdpi.com)
These labs are joined by our UTSW Distinguished Fellow, Scott Saunders , who develops revolutionary technology for editing bacterial genomes with unprecedented efficiency to accelerate experimentation. (utsouthwestern.edu)

Thus, E. chaffeensis is an excellent model organism to study host-pathogen interactions and to understand the molecular pathobiology of obligately intracellular microbes. (frontiersin.org)

To a molecular biologist, a textbook so heavily focused on the classical genetics of model systems such as Escherichia coli and Bacillus subtilis might, at first glance, come across as "been there, done that. (cdc.gov)
Using antibodies, we demonstrated that the regulation of both Listeria monocytogenes PPDK and Escherichia coli PEP synthetase involves the phosphorylation of a threonine residue located close to the catalytic histidine residue. (scirp.org)
Expression of the Escherichia coli tryptophanase operon depends on ribosome stalling during translation of the upstream TnaC leader peptide, a process for which interactions between the TnaC nascent chain and the ribosomal exit tunnel are critical. (cipsm.de)
RNP-based processive anti-termination underlies the switching from immediate-early to delayed-early gene expression in other lambdoid phages as well as ribosomal RNA synthesis in Escherichia coli . (fu-berlin.de)

Resistance arises by mutation (influencing the target or efflux of the antimicrobial agent) or by the acquisition of resistance genes (encoding antimicrobial or target alter- ation, or alternate pathways) (2,3). (cdc.gov)

Ribosome-mediated attenuation is a gene expression mechanism in which a transcriptional termination signal is regulated by translation. (wikipedia.org)
Her lab is interested in investigating how transcriptional networks underlie the regulation of gene expression during biofilm development. (ucmerced.edu)
Microbiological and gene expression data correlated in four instances, existing knowledge of the substrate specificity of NorC resulted in correlation in two others, and a transcriptional/translational disconnect is possible for the remaining two. (manchester.ac.uk)
Gene regulation, RNA processing and Post transcriptional modifications. (nipaers.com)
We also study selected RNP-remodeling enzymes as drivers of molecular RNP machineries and as mediators of co- and post-transcriptional gene regulation. (fu-berlin.de)
Transcriptional regulation of the genes in metabolic pathways is a highly successful strategy, which is virtually universal in microorganisms. (lu.se)
With a minimalist model of metabolism, cell growth and transcriptional regulation in a microorganism, we explore how the interaction between environmental conditions and gene regulation set the growth rate of cells in the phase of exponential growth. (lu.se)
Citation: Troein C, Ahre´n D, Krogh M, Peterson C (2007) Is Transcriptional Regulation of Metabolic Pathways an Optimal Strategy for Fitness? (lu.se)
INTRODUCTION broken, which in realistic situations can severly constrain the Transcriptional regulation of effector genes is a highly successful regulatory options. (lu.se)
Activation of Btk results in a cascade of signaling events resulting in calcium mobilization and fluxes, cytoskeletal rearrangements, and transcriptional regulation involving nuclear factor-kappaB (NF-kappaB) and nuclear factor of activated T cells (NFAT). (medscape.com)
Transcriptional regulation of aquaporins in accessions of Arabidopsis in response to drought stress. (lu.se)

2022 ) Gene Expression Regulation in Airway Pathogens: Importance for Otitis Media. (lu.se)
Bacterial pathogens are a serious and growing threat to human health due to the continued emergence of antibiotic resistance, which limits our ability to treat infections. (illinois.edu)
Critical to the ability of pathogens to overcome nutritional immunity is the expression of dedicated metal uptake systems that allow invaders to fight with the host for metals. (illinois.edu)
It is the body's first-line defense against many bacterial pathogens. (medscape.com)
Antimicrobial resistance in bacterial pathogens is a major impediment to successful therapy, and in sever- al instances, bacterial strains have arisen that are refracto- ry to most available antimicrobial treatments (1). (cdc.gov)

Horizontal gene transfer plays a major role in microbial evolution by innovating the bacterial genome with new genetic blueprints to adapt to previously unexploited niches. (mcmaster.ca)
Microbiological, quantitative gene expression, mRNA half-life and genome data for 11 strains of S. aureus combined with bioinformatic analyses were used to identify correlates of increased MDR EP gene expression. (manchester.ac.uk)
RESULTS: Draft genome sequencing, gene expression analysis, and proteomic analysis revealed that NaphS2 degrades naphthoyl-CoA in a manner analogous to benzoyl-CoA degradation. (elsevierpure.com)
In this study, we employed a genome-wide CRISPR-Cas9 loss-of-function screen based on cell survival in order to identify genes implicated in the host response to dsRNA. (cnrs.fr)
Using a genome-wide screening approach, we set to identify genes involved in dsRNA entry, sensing, and apoptosis induction in human cells. (cnrs.fr)
Adenovirus DNA : the viral genome and its expression / edited by Walter Doerfler. (who.int)

The lab is also beginning to study interspecies interactions between different fungal and bacterial species. (ucmerced.edu)
The biochemical data available on SKs, particularly their molecular interactions with signals, nucleotides, and their cognate RRs, are also reviewed. (nih.gov)
Our group is interested in the research of clinically relevant bacterial species that mainly cause upper and lower airway infections and their interactions with the host. (lu.se)
Enhancing our understanding of how molecular interactions at the atomic level have consequences for the genetic activity of a cell brings new avenues for medical research. (sciencedaily.com)

While previous studies have characterized bacterial growth physiology at steady-state, a quantitative understanding of bacterial physiology in time-varying environments is lacking. (nature.com)
To understand the dynamics of bacterial growth physiology and size control in dynamic nutrient environments, we have developed a coarse-grained proteome sector model which connects gene expression to growth rate and division control, and accurately predicts the cell-level E. coli response to nutrient perturbations in both exponential and stationary phase seen in experimental data 5 , 25 . (nature.com)
By coupling advances in the basic science of bacterial physiology with new tools in deep learning, cell simulation, and bacterial genetics, we aim to transform the process of cellular engineering. (utsouthwestern.edu)

DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. (cipsm.de)

Furthermore, it is unclear if bacterial size modulation is simply a byproduct of the complex cellular response to changing environmental conditions, or if it serves as an adaptive mechanism employed by the cell to improve fitness in time-varying environments. (nature.com)
This course integrates information into the context of regulation of cellular function. (charlotte.edu)
Among those molecular cues, double-stranded RNA (dsRNA) is a very potent inducer of different reactions at the cellular level that can ultimately lead to cell death. (cnrs.fr)
Cellular and molecular life sciences : CMLS. (zfin.org)

By identifying genes that have undergone regulatory evolution, a deeper understanding of the arms race between host and pathogen is gained. (mcmaster.ca)
The correlations proposed provide a guide for further experimentation leading to a better understanding of MDR EP gene expression in this important pathogen. (manchester.ac.uk)
Higher eukaryotes sense microbes through the perception of pathogen-associated molecular patterns (PAMPs). (uea.ac.uk)
Mutations in all six genes cause resistance to the bacterial pathogen Microbacterium nematophilum, and most of these mutations also affect bacterial adhesion and biofilm formation by Yersinia species, demonstrating that both infection and biofilm formation depend on interaction with complex surface carbohydrates. (ox.ac.uk)
A deletion allele of egl-5 was isolated in a screen for animals which fail to develop swollen tails when exposed to the bacterial pathogen Microbacterium nematophilum. (ox.ac.uk)
Current studies are focused on elucidating how the selective pressures encountered during infection shape the repertoire of metalloenzymes possessed by a pathogen and their expression. (illinois.edu)

Transcription-translation coupling is a mechanism of gene expression regulation in which synthesis of an mRNA (transcription) is affected by its concurrent decoding (translation). (wikipedia.org)
For amino acid biosynthesis operons, these allow the gene expression machinery to sense the abundance of the amino acid produced by the encoded enzymes, and adjust the level of downstream gene expression accordingly: transcription occurring only if the amino acid abundance is low and the demand for the enzymes is therefore high. (wikipedia.org)
Extensive regulation by σS of genes involved in metabolism and membrane composition, and down-regulation of the respiratory chain functions, were important features of the σS effects on gene transcription that might confer fitness advantages to bacterial cells and/or populations under starving conditions. (hal.science)
Members of the Hox gene family encode transcription factors that specify positional identity along the anterior-posterior axis of nearly all metazoans. (ox.ac.uk)
The latter might seem impossible, as an arbitrary transcription factor normally exists in just a handful of copies inside a bacterial cell, and one of them has to find a specific binding site on the DNA spiral, which contains some five million base pairs, in order to turn a gene on or off," says Erik Marklund, one of the lead authors of the new study. (sciencedaily.com)

Four of the Center's eight faculty research labs ( Kim , Lin , Reynolds , and Toprak ) are collectively working to elucidate and eventually program this molecular circuitry in the context of metabolic regulation and antibiotic resistance. (utsouthwestern.edu)
A number of studies have explored how regulation of generally, and at least to a first approximation, it is obvious that metabolic pathways affects the growth rate of microorganisms, gene regulation only is useful if the environmental conditions vary both in the steady state and in response to changes in the local with time. (lu.se)

The involvement of some of the genes in the biosynthesis of rifamycin B was examined. (nih.gov)
Disruption of the PKS genes at the end of rifA abolished rifamycin B production and resulted in the formation of P8/1-OG, a known shunt product of rifamycin biosynthesis, whereas disruption of the orf6 and orf9 genes, which may encode deoxysugar biosynthesis enzymes, had no apparent effect. (nih.gov)

DAMPs, damage-associated tissues and the molecular target structures and pathways. (cdc.gov)

The introduction and first chapter, The Bacterial Chromosome, are designed to provide a basic background in genetics. (cdc.gov)
Gene cloning and sub-cloning strategies, chromosome walking, genetic transformation, Basis of animal cloning. (nipaers.com)
During growth at environmental temperatures, we show for the first time that pINV spontaneously integrates into different sites in the chromosome, and this is mediated by inter-molecular events involving IS1294. (ox.ac.uk)
Integration leads to reduced PAI gene expression and impaired secretion through the T3SS, while excision of pINV from the chromosome restores T3SS function. (ox.ac.uk)
In this study, we have developed a new approach, namely bacterial artificial chromosome-rescue-based knockout (BACK), to achieve conditional gene knockout in zebrafish using the Cre/loxP system. (zfin.org)

A very natural place to study gene detecting and metabolizing lactose, it is known that the overall regulation is in the metabolism of the cell, and then specifically in effect of expressing the lac genes in vain is a drop in the growth rate the regulation of genes that code for enzymes and transporter of as much as 5% [1,6]. (lu.se)

So far, one network which is involved in the regulation of listerial virulence, the PrfA regulon, has been characterized rather well. (ed.ac.uk)
The analysis of virulence gene expression in vivo, i.e. in infected host cells, indicates that yet uncharacterized bacterial factors other than PrfA, and possibly also host factors, modulate the expression of the PrfA regulon. (ed.ac.uk)
Fermentable carbon sources seem to have a particular role in virulence gene regulation. (ed.ac.uk)
Genetic plasticity of the Shigella virulence plasmid is mediated by intra- and inter-molecular events between insertion sequences. (ox.ac.uk)

Current estimates of the number of bacterial species range from 1 to 1000 million. (lu.se)

These observations suggest genetic variants can decrease mRNA expression levels by increasing usage of intronic PAS. (elifesciences.org)

Blister fluids were collected for proteomic analyses and molecular assessment of the presence of venom and antivenom. (bvsalud.org)

There is much to gain from uncovering the genetic diversity in noncoding DNA that is selective during host infection because of the beneficial effect it has on bacterial gene expression. (mcmaster.ca)
The C. elegans Hox gene egl-5 is required for correct development of the hermaphrodite hindgut and for the response to rectal infection by Microbacterium nematophilum. (ox.ac.uk)
We show that compromised rectal development, which occurs as a result of loss of egl-5 function, results in a failure of rectal epithelial cells to express the ERK MAP kinase mpk-1, which was previously shown to mediate tail-swelling in response to bacterial infection. (ox.ac.uk)
Together these findings extend the complexity of regulation and function of Hox genes in C. elegans and demonstrate the importance of their tissue-specific expression for correct development and response to infection. (ox.ac.uk)

Increasing gene dosage greatly enhances recombinant expression of aquaporins in Pichia pastoris. (lu.se)

Professor Nobile's research is directed toward understanding the molecular and mechanistic basis of microbial communities. (ucmerced.edu)

The actual origins of acquired resistance genes are unknown, but environmental microbes, including the strains producing antimicrobial agents, are believed to be important sources (4,5). (cdc.gov)

However, the arrest code dictating whether a given nascent peptide is prone to inhibiting its own synthesis is yet to be elucidated, the range of metabolites that can be sensed by the nascent peptide is unknown and the molecular bases of the arrest mechanism itself are only partially understood. (u-bordeaux.fr)

At least five genes were shown to be essential for the synthesis of AHBA, five genes were determined to encode the modular type I PKS that uses AHBA as the starter unit, and 20 or more genes appear to govern modification of the polyketide-derived framework, and rifamycin resistance and export. (nih.gov)
The BTK gene is large and consists of 19 exons that encode the 659 amino acids that form the Btk cytosolic tyrosine kinase. (medscape.com)

In particular, exposure to CAS resulted in the upregulation of hypha-specific genes known to play a role in biofilm formation, such as ALS3 and HWP1. (who.int)

Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans. (ox.ac.uk)
One among the Caenorhabditis elegans Hox genes is egl-5. (ox.ac.uk)

Theories of evolution and forces which affect gene frequencies. (charlotte.edu)

Moreover, we present strong evidence that Mg(2+) signals through CsrS to regulate an extensive and previously undefined repertoire of GAS genes. (lu.se)

Thus, arrest peptides are used for metabolite-dependent gene regulation in both prokaryotes and eukaryotes. (u-bordeaux.fr)

Mutations can occur in any area of the gene. (medscape.com)
Murine gene mutations in human counterparts may be associated with a clinical illness different from the illness seen in mice. (medscape.com)

The immunopathogenesis of many human diseases is characterized at the molecular level. (medscape.com)

The microbiological section deals with basic molecular aspects of prokaryotic cells. (uni-wuerzburg.de)

Clearly, interspecies bacterial communication influences the regulation of gene expression. (asmblog.org)

A new bacterial interaction, involving locomotory inhibition by a strain of Bacillus pumilus, reveals diversity in the surface properties of these mutants. (ox.ac.uk)
Another biological property--contact recognition of hermaphrodites by males during mating--was also found to be impaired in mutants of all six genes. (ox.ac.uk)
To test for possible redundancies in gene action, the 15 double mutants for this set of genes were constructed and examined, but no synthetic phenotypes were observed. (ox.ac.uk)
The creation and isolation of specific mutants is a cornerstone of bacterial genetics. (lu.se)

The presence of qacA/B and/or increased expression of one to two MDR EP genes were identified in eight strains. (manchester.ac.uk)
The T3SS imposes a significant cost on the bacterium, and strains which have lost the plasmid and/or genes encoding the T3SS grow faster than wild-type strains in the laboratory, and fail to bind the indicator dye Congo Red (CR). (ox.ac.uk)

The expression of the bacterial genes involved in the different steps of the infectious process--invasion, intracellular multiplication and spreading--is temporally and spatially controlled, thus ensuring the presence of the respective gene products at the right moment and place. (ed.ac.uk)

deletions occur through intra-molecular recombination events between insertion sequences (ISs) flanking the PAI. (ox.ac.uk)

Anatomy23

Organisms16

Diseases4

Chemicals and Drugs65

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Phenomena and Processes99

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