Checkpoint Kinase 2Protein-Serine-Threonine KinasesProtein KinasesCell Cycle ProteinsDNA DamageAtaxia Telangiectasia Mutated ProteinsGenes, cdcG2 PhaseCell CycleMitosisM Phase Cell Cycle CheckpointsPhosphorylationS PhaseCell Cycle CheckpointsProtein Kinase InhibitorsPhosphatidylinositol 3-Kinasescdc25 PhosphatasesDNA ReplicationHydroxyureaMutationMAP Kinase Signaling SystemSaccharomyces cerevisiae ProteinsCDC2 Protein KinaseSpindle ApparatusSchizosaccharomyces pombe ProteinsG2 Phase Cell Cycle CheckpointsDNA-Binding ProteinsSchizosaccharomycesNuclear ProteinsTumor Suppressor ProteinsIntracellular Signaling Peptides and ProteinsCell Line, TumorS Phase Cell Cycle CheckpointsKinetochoresDNA RepairSignal TransductionSaccharomyces cerevisiaeTumor Suppressor Protein p53Calcium-Calmodulin-Dependent Protein KinasesRNA, Small InterferingProtein-Tyrosine KinasesApoptosissrc-Family KinasesHeLa CellsProtein BindingRadiation, IonizingEnzyme ActivationNocodazoleCyclin-Dependent KinasesModels, BiologicalMolecular Sequence DataBlotting, WesternCell LineCdc20 Proteinsp38 Mitogen-Activated Protein KinasesG1 PhaseProtein Kinase CCell DivisionMethyl MethanesulfonateRNA InterferenceAurora KinasesDNA Breaks, Double-StrandedCell SurvivalGenomic InstabilityUltraviolet RaysHistonesCyclic AMP-Dependent Protein KinasesAntineoplastic AgentsMitogen-Activated Protein Kinase 1Amino Acid SequenceNeoplasmsEarly Detection of CancerCyclin BFungal ProteinsTransfectionChromosome SegregationDNA, FungalProtein Structure, TertiaryMitogen-Activated Protein Kinase KinasesBreast NeoplasmsJNK Mitogen-Activated Protein Kinasesp21-Activated KinasesMitogen-Activated Protein Kinase 3Gamma RaysCell ProliferationColonic NeoplasmsHCT116 CellsCell NucleusSerineRNA, MessengerBase SequenceEnzyme InhibitorsTumor Cells, CulturedStaurosporineImmunoblottingProto-Oncogene ProteinsMAP Kinase Kinase KinasesDown-RegulationReplication Protein ACarrier Proteins