• ovotoxic
  • Exposure of women to chemicals that are ovotoxic in laboratory animals (chemotherapeutic agents, contaminants of cigarette smoke) is known to be associated with early menopause. (springer.com)
  • 1983
  • Anderson PW (1983) Suggested model for prebiotic evolution: the use of chaos. (springer.com)
  • The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1983, for his contributions to chemical sciences. (wikipedia.org)
  • Sciences
  • It was established in 1961 as the Journal of Chemical Documentation, renamed in 1975 to Journal of Chemical Information and Computer Sciences, and obtained its current name in 2005. (wikipedia.org)
  • The journal is abstracted and indexed in: Chemical Abstracts Service Scopus ProQuest databases Science Citation Index Current Contents/Physical, Chemical & Earth Sciences Index Medicus/MEDLINE/PubMed. (wikipedia.org)
  • atoms
  • According to his model for a diatomic molecule, the electrons of the atoms of the molecule form a rotating ring whose plane is perpendicular to the axis of the molecule and equidistant from the atomic nuclei. (wikipedia.org)
  • mathematical
  • Sensitivity analysis is the study of how the uncertainty in the output of a mathematical model or system (numerical or otherwise) can be apportioned to different sources of uncertainty in its inputs. (wikipedia.org)
  • constants
  • Rate constants Not required for steady state modeling! (coursehero.com)
  • EDC has been proven efficient without the need for changing the constants for a great variety of premixed and diffusion controlled combustion problems, both where the chemical kinetics is faster than the overall fine structure mixing as well as in cases where the chemical kinetics has a dominating influence. (wikipedia.org)
  • wide range
  • Jmol supports a wide range of chemical file formats, including Protein Data Bank (pdb), Crystallographic Information File (cif), MDL Molfile (mol), and Chemical Markup Language (CML). (wikipedia.org)
  • hydrogen
  • Thus, according to this model, the methane molecule is a regular tetrahedron, in which center the carbon nucleus locates, and in the corners - the nucleus of hydrogen. (wikipedia.org)
  • simulations
  • The beauty of COMSOL is that it provides a unified modeling platform no matter what type of simulations you are performing. (comsol.nl)
  • Rokhsar DS, Anderson PW, Stein DL (1986) Self-organization in prebiological systems: simulations of a model for the origin of genetic information. (springer.com)
  • biological
  • In: Peliti L (ed) Disordered systems and biological models. (springer.com)
  • In contrast to traditional methods of drug discovery (known as forward pharmacology), which rely on trial-and-error testing of chemical substances on cultured cells or animals, and matching the apparent effects to treatments, rational drug design (also called reverse pharmacology) begins with a hypothesis that modulation of a specific biological target may have therapeutic value. (wikipedia.org)
  • ovarian
  • Environmental chemicals that destroy oocytes contained in these follicles can produce premature ovarian failure (early menopause in women) because once destroyed, they cannot be replaced. (springer.com)
  • P.B. Hoyer, and I.G. Sipes, Assessment of follicle destruction in chemical-induced ovarian toxicity. (springer.com)
  • physical
  • Chemical process modeling requires a knowledge of the properties of the chemicals involved in the simulation, as well as the physical properties and characteristics of the components of the system, such as tanks, pumps, pipes, pressure vessels, and so on. (wikipedia.org)
  • systems
  • Derrida B (1981) Random-energy model: an exactly solvable model of disordered systems. (springer.com)
  • TCAM is developed by the ESMA (Environmental Systems Modeling and Assessment) group of University of Brescia. (wikipedia.org)
  • He propose this model first in the article "Systems containing several nuclei" - the third and last of the classic series of articles by Bohr, published in November 1913 in Philosophical Magazine. (wikipedia.org)
  • environmental
  • Examples are the European Commission (see e.g. the guidelines for impact assessment), the White House Office of Management and Budget, the Intergovernmental Panel on Climate Change and US Environmental Protection Agency's modelling guidelines. (wikipedia.org)
  • important
  • The present series ofbooks dwells on the most important models of chemical bonding and on the variety of its manifestations. (springer.com)
  • To seek to identify important connections between observations, model inputs, and predictions or forecasts, leading to the development of better models. (wikipedia.org)
  • cellular
  • Researchers at Penn State University have developed a chemical model that mimics a possible step in the formation of cellular life on Earth four-billion years ago. (scitechdaily.com)
  • Bond
  • In addition to the model of the atom, Niels Bohr also proposed a model of the chemical bond. (wikipedia.org)
  • The Bohr model of the chemical bond took into account the Coulomb repulsion - the electrons in the ring are at the maximum distance from each other. (wikipedia.org)
  • However, such a peptide, after a modification on its scissile bond with some simple chemical procedure, will completely lose its cleavability but it can still tightly bind to the enzyme's active site. (wikipedia.org)
  • laboratory
  • Dr Vivek V Ranade is a Deputy Director of CSIR - National Chemical Laboratory (www.ncl-india.org) and Chairman of Chemical Engineering and Process Development Division. (elsevier.com)
  • system
  • The process of recalculating outcomes under alternative assumptions to determine the impact of a variable under sensitivity analysis can be useful for a range of purposes, including: Testing the robustness of the results of a model or system in the presence of uncertainty. (wikipedia.org)
  • Increased understanding of the relationships between input and output variables in a system or model. (wikipedia.org)
  • Further, models may have to cope with the natural intrinsic variability of the system (aleatory), such as the occurrence of stochastic events. (wikipedia.org)
  • species
  • but a CTM will be expected to accurately represent the entire cycle for the species of interest, including fluxes (e.g. advection), chemical production/loss, and deposition. (wikipedia.org)
  • demonstrate
  • Weak coupling with monotonic (bistable) dynamical regimes demonstrate spatial chaos phenomena and are popular in neural models. (wikipedia.org)
  • large
  • In case of calibrating models with large number of parameters, a primary sensitivity test can ease the calibration stage by focusing on the sensitive parameters. (wikipedia.org)
  • Some of the most common are Computational expense: Sensitivity analysis is almost always performed by running the model a (possibly large) number of times, i.e. a sampling-based approach. (wikipedia.org)
  • The model has a large number of uncertain inputs. (wikipedia.org)
  • Some methods of reducing computational expense include the use of emulators (for large models), and screening methods (for reducing the dimensionality of the problem). (wikipedia.org)