• There has been rapid progress in transcatheter therapies for mitral regurgitation. (nih.gov)
  • Pre- and intraoperative echocardiography for surgical mitral valve repair for mitral regurgitation has defined contemporary interventional imaging in many ways. (nih.gov)
  • The expanded use of pre-procedural cardiac magnetic resonance to quantify mitral regurgitation and characterize the left ventricle is another illustration of this newer approach. (nih.gov)
  • This review provides an update of the essentials in present interventional imaging for surgical and transcatheter interventions for mitral regurgitation. (nih.gov)
  • Supravalvar mitral stenosis can develop as an acquired lesion late after mitral annuloplasty to repair mitral regurgitation . (medscape.com)
  • The same mechanism is responsible for the acquired variety of supravalvar mitral stenosis that occurs after mitral annuloplasty for repair of mitral regurgitation. (medscape.com)
  • Both groups presented a decrease in the severity of mitral and tricuspid regurgitation at 3-24 months. (frontiersin.org)
  • Recurrent mitral regurgitation (MR) is frequently encountered after mitral valve repair, particularly in cases of ischemic MR ( 2 ). (frontiersin.org)
  • The field of transcatheter mitral valve repair (TMVr) for mitral regurgitation (MR) is rapidly evolving. (bmj.com)
  • Mitral regurgitation (MR) contributes to significant morbidity and mortality. (bmj.com)
  • PASCAL repair system for patients with mitral regurgitation: A systema" by Aswin Srinivasan, Jonathan Brown et al. (hcahealthcare.com)
  • PASCAL repair system for patients with mitral regurgitation: A systematic review. (hcahealthcare.com)
  • BACKGROUND: Transcatheter edge-to-edge repair (TEER) of the mitral valve has emerged as the standard treatment for patients with mitral regurgitation (MR) with high surgical risk. (hcahealthcare.com)
  • Srinivasan A, Brown J, Ahmed H, Daniel M. PASCAL repair system for patients with mitral regurgitation: A systematic review. (hcahealthcare.com)
  • Transcatheter mitral valve implantation represents a promising approach to treating mitral regurgitation in patients at increased risk of perioperative mortality. (researcher-app.com)
  • The procedures were successfully performed in a 69-year-old man and a 65-year-old woman with severe functional mitral regurgitation. (researcher-app.com)
  • Patient #2 expired 4 days after a technically successful procedure, because the left ventricle did not tolerate the reduction of mitral regurgitation and despite a high dose of inotropic agents the left ventricular function rapidly deteriorated. (researcher-app.com)
  • Mitral transcatheter edge-to-edge repair (M-TEER) has been established as a treatment approach in symptomatic severe mitral regurgitation (MR) patients. (pcronline.com)
  • This in turn, causes volume overload that exacerbates the myopathy, leading to a vicious cycle of progressive enlargement and worsening mitral regurgitation. (justia.com)
  • Restrictive mitral valve annuloplasty versus mitral valve replacement for functional ischemic mitral regurgitation: an exercise echocardiographic study. (rush.edu)
  • Determinants of functional capacity after mitral valve annuloplasty or replacement for ischemic mitral regurgitation. (rush.edu)
  • Exercise Hemodynamic and Functional Capacity After Mitral Valve Replacement in Patients With Ischemic Mitral Regurgitation: A Comparison of Mechanical Versus Biological Prostheses. (rush.edu)
  • It remains early days for transcatheter mitral-valve replacement (TMVR) as a minimally invasive way to treat severe, mitral regurgitation (MR), but it's even earlier days for TMVR as an endovascular procedure. (medscape.com)
  • The patient underwent seven years ago to aortic valve replacement (AVR) with 25 mm On-X (On-X Life Technology Inc., Austin, TX, USA) mechanical prosthesis for severe aortic valve regurgitation and ascending aorta replacement with a tube graft n 28 for ascending aorta aneurysm. (biomedcentral.com)
  • The transesophageal echocardiogram (TEE) confirmed the severe aortic regurgitation, showing an aortic non coronary sinus PVL with a partial detachment of aortic prosthesis. (biomedcentral.com)
  • MitraClip Deployed via Left Femoral Vein in an 85-Year-Old Woman with Mitral Regurgitation. (ouhsc.edu)
  • Enlargement of the mitral annulus and left ventricular cavity produce mitral valvular insufficiency. (justia.com)
  • Although mitral valve repair and replacement can successfully treat many patients with mitral valvular insufficiency, techniques currently in use are attended by significant morbidity and mortality. (justia.com)
  • Insufficiency of the mitral valve causing flow of blood from the left ventricle (LV) into the left atrium during ventricular systole. (msdmanuals.com)
  • We retrospectively identified patients with degenerated mitral bioprosthesis or failed annuloplasty rings who underwent redo SRMVR or TAMVI at our medical center. (frontiersin.org)
  • We retrospectively identified patients with symptomatic mitral bioprosthetic valve dysfunction ( n = 58) and failed annuloplasty rings ( n = 14) who underwent redo SRMVR ( n = 36) or TAMVI ( n = 36). (frontiersin.org)
  • Transapical transcatheter mitral valve-in-valve implantation (TAMVI) is now regarded as a promising alternative treatment for patients with degenerated bioprosthesis or failed annuloplasty ( 3 ). (frontiersin.org)
  • There have been a relatively small number of reports pertaining to the clinical outcomes and echocardiographic findings following TAMVI or surgical redo mitral valve replacement (SRMVR) for degenerated bioprosthetic valve or failed annuloplasty rings. (frontiersin.org)
  • I. Transcatheter mitral annuloplasty. (bmj.com)
  • The purpose of surgical and transcatheter mitral annuloplasty is to reduce the annular circumference and obtain better coaptation of the mitral leaflets. (bmj.com)
  • Mitral annuloplasty techniques using transcatheter approaches can be classified as indirect or direct, based on their relation to the mitral annulus. (bmj.com)
  • One repair technique which has been shown to be effective in treating incompetence, particularly of the mitral and tricuspid valves, is annuloplasty, in which the effective size of the valve annulus is contracted by attaching a prosthetic annuloplasty ring to the endocardial surface of the heart around the valve annulus. (justia.com)
  • Over the past two decades, transcatheter aortic valve implantation (TAVI) has been established as a viable alternative treatment to deal with severe aortic stenosis in patients at risk of open-heart surgery. (frontiersin.org)
  • Alain Cribier is best known for performing the world's first transcatheter aortic valve implantation in 2002, the first mitral commissurotomy in 1995 and the first balloon aortic valvuloplasty in 1986. (wikipedia.org)
  • John G. Webb - performed the first transapical transcatheter aortic valve implantation in 2006 Cribier, Alain (November 25, 2002). (wikipedia.org)
  • Until the recent development of a whole new technique for the transplant of the aortic valve through a catheter, Transcatheter Aortic Valve Implantation known as TAVI, the only treatment possible was an open-heart surgery where the diseased valve was substituted by a mechanical aortic valve or by a biological one. (portugalresident.com)
  • The elongate body is movable from a first, flexible configuration for transluminal delivery to at least a portion of the coronary sinus to a second configuration for remodeling the mitral valve annulus. (justia.com)
  • The percutaneous solution, as the name indicates, consists of the introduction of a biological valve prosthesis applied with the use of a metallic stent, through a small incision in the groin. (portugalresident.com)
  • Uncommonly associated defects include atrial septal defect , cor triatriatum, left superior vena cava, unroofed coronary sinus, partial anomalous pulmonary venous drainage, pulmonary venous obstruction, double-orifice mitral valve, and Wolff-Parkinson-White syndrome . (medscape.com)
  • Newer generationmechanical valves have shown less PPM than older generation, and stentless bioprosthesis have less PPM than stented prosthesis.Long-termclinical outcome of PPMis associatedwith adverse cardiovascular events especially in the presence of pre-existing left ventricle dysfunction or with concomitant procedure such as coronary artery bypass graft surgery. (ochsner.org)
  • A medical apparatus and method for remodeling a mitral valve annulus adjacent to the coronary sinus includes an elongate body having a proximal end and a distal end. (justia.com)
  • The surgical findings confirmed a partial prosthesis detachment at the level of the non coronary aortic sinus, due to the semicontinuous suture breaking (Figure 2 ). (biomedcentral.com)
  • Use of a hybrid operating room to diagnose and treat delayed coronary spasm after mitral valve repair. (bu.edu)
  • The operative mortality rate in first-time valve procedures was 1.8% in isolated aortic valve replacement, 0.9% in isolated mitral valve repair, and 8.2% and 4.6% in mitral valve replacement with biological prostheses and with mechanical prostheses, respectively. (elsevierpure.com)
  • The study population consisted of adult patients who underwent one of three types of valve surgery: isolated aortic valve replacement (n = 67,292), isolated mitral valve replacement (n = 21,229), or isolated mitral valve repair (n = 21,238). (nih.gov)
  • Shone complex is a combination of four congenital heart defects: supravalvar mitral ring, parachute mitral valve, subvalvar aortic stenosis, and aortic coarctation. (medscape.com)
  • For example, mechanical and tissue-based heart valve prostheses can be used to replace impaired native heart valves. (justia.com)
  • Patients submitted to valvar reoperations make up a very heterogeneous group, since they include patients with structural dysfunction of bioprostheses or valvar re-stenosis, endocarditis in prostheses, para-valvar escape or mechanical prosthesis thrombosis. (rbccv.org.br)
  • Prospective randomized comparison of CarboMedics and St Jude Medical bileaflet mechanical heart valve prostheses: an interim report. (rush.edu)
  • Such patients often require the implantation of a valve prosthesis - mechanical or biological. (scardio.ru)
  • Unlike the mechanical prosthesis, the biological one is less thrombogenic on the one side and has a shorter life duration on the other side. (scardio.ru)
  • The patients undergone the operation for the replacement of the heart valves by the mechanical prostheses are at the risk of developing thromboembolic complications, the most formidable of which are thrombosis of valve prostheses and disabling strokes, which, in turn, can lead to the death of a patient [2][3]. (scardio.ru)
  • Thromboembolism can be caused by the following: the occurrence of turbulent blood flow and blood stasis, which are created by the implanted valve itself, as well as high thrombogenicity of the mechanical prosthesis material [4]. (scardio.ru)
  • A comparative study of minimally invasive aortic valve replacement with sutureless biological versus mechanical prostheses. (150.254.179)
  • After the prosthesis explant, a new aortic mechanical prosthesis was implanted (23 mm S. Jude, S. Jude Medical, St. Paul, MN, USA), using interrupted suture technique with 2-0 Ethibond (Ethicon) polytetrafluoroethylene (Teflon)-buttressed stitches. (biomedcentral.com)
  • He performed the world's first mitral commissurotomy in 1995. (wikipedia.org)
  • Other valve repair techniques in current use include commissurotomy (cutting the valve commissures to separate fused valve leaflets), shortening mitral or tricuspid valve chordae tendonae, reattachment of severed mitral or tricuspid valve chordae tendonae or papillary muscle tissue, and decalcification of the valve leaflets or annulus. (justia.com)
  • Often circumferential in shape, the supravalvar ring may encroach on the orifice of the mitral valve and may adhere to the leaflets of the valve and restrict their movements. (medscape.com)
  • The membrane is distinct from and not adherent to the mitral valve leaflets. (medscape.com)
  • The intramitral variant is a membrane located within the mitral tunnel, closely adherent to the valve leaflets. (medscape.com)
  • This subtype is associated with a high incidence of mitral valve abnormalities, including restricted mobility of the mitral leaflets, reduced chordal length, reduced interpapillary muscle distance, single papillary muscle, or hypoplastic mitral annulus. (medscape.com)
  • This variety may be difficult to detect because the membrane often adheres to mitral valve leaflets. (medscape.com)
  • Adhesion to the valve may impair opening of the leaflets, and this impairment may be the main mechanism of mitral valve inflow obstruction in some patients. (medscape.com)
  • Disclosed herein are embodiments of an expandable replacement heart valve prosthesis. (justia.com)
  • The expandable replacement heart valve prosthesis can include a number of different features, such as an hourglass (or generally hourglass) shape in the fully expanded position, anchor stiffening features, and improved retraction/retention configurations. (justia.com)
  • Regarding minimally invasive procedures, 30.8% of first-time isolated mitral valve plasty procedures were performed by a right thoracotomy. (elsevierpure.com)
  • Operating for over 22 years, the Cardiovascular Intervention Unit of Hospital Particular in Alvor has in its curriculum thousands of interventions and procedures, including minimally invasive cardiovascular intervention techniques, catheterization, angioplasty and transcatheter implants of the aortic and mitral valves. (portugalresident.com)
  • Minimally invasive mitral valve repair suggests earlier operations for mitral valve disease. (bu.edu)
  • Mitral valve repair can be performed either through open-heart surgery or minimally invasive techniques such as robotic surgery. (medginnie.com)
  • Mitral valve disease is the most common valvular disease in developed countries. (frontiersin.org)
  • The advent of transcatheter mitral valve repair (TMVr) therapies has provided feasible and safe alternatives to medical and surgical treatment-especially for those patients who are not considered suitable candidates for conventional mitral valve surgery. (bmj.com)
  • The last published STS model for isolated valve surgery was based on data from 1994 to 1997 and did not include patients undergoing mitral valve repair. (nih.gov)
  • The new STS risk models for valve surgery include mitral valve repair as well as multiple endpoints other than mortality. (nih.gov)
  • What Exactly Makes Age a Risk Factor for an Unfavorable Outcome after Mitral Valve Surgery? (mdpi.com)
  • Propensity-matched analysis of outcomes after mitral valve surgery between trainees and consultants (institutional report). (rush.edu)
  • Predictors of survival in octogenarians after mitral valve surgery for degenerative disease: The Mitral Surgery in Octogenarians study. (rush.edu)
  • Cost of Surgery just 1/6th of cost in USA, UK or Europe with finest quality implants, prosthesis and consumables imported from Leading International Companies. (medginnie.com)
  • Computer Navigation Surgery System for excellent outcomes and use of finest quality implants, prosthesis and consumables imported from Leading International Companies. (medginnie.com)
  • Although a supravalvar mitral ring may allow for normal hemodynamic flow from the left atrium to the left ventricle (LV), it often substantially obstructs mitral valve inflow. (medscape.com)
  • The mitral valve is a Heart Valve Replacement that separates the left atrium from the left ventricle and controls the flow of blood from the atrium to the ventricle. (medginnie.com)
  • Currently, TMVR is approved in the United States only using one device designed for the aortic position and only for treating failed surgical mitral bioprostheses in high-risk patients. (medscape.com)
  • Surgical insertion of BLOOD VESSEL PROSTHESES to repair injured or diseased blood vessels. (lookformedical.com)
  • The supramitral type is a fibrous shelflike membrane located just above the mitral valve annulus but inferior to the left atrial appendage. (medscape.com)
  • Besides the well-established transcatheter mitral edge-to-edge repair approach, there is also growing evidence for therapeutic strategies targeting the mitral annulus and mitral valve chordae. (bmj.com)
  • According to a "parachute technique" the sutures were suspended (left loose) to enable an easier suturing of the aortic annulus and sewing ring of the artificial valve prior to lower the prosthesis. (biomedcentral.com)
  • In particular, certain embodiments relate to expandable prostheses such as replacement heart valves, such as for the mitral valve, that are configured to be secured to intralumenal tissue and prevent paravalvular leakage. (justia.com)
  • Human heart valves, which include the aortic, pulmonary, mitral and tricuspid valves, function essentially as one-way valves operating in synchronization with the pumping heart. (justia.com)
  • Prostheses exist to correct problems associated with impaired heart valves. (justia.com)
  • In this study, transapical transcatheter mitral valve-in-valve implantation (TAMVI) was compared with surgical redo mitral valve replacement (SRMVR) in terms of clinical outcomes. (frontiersin.org)
  • [ 1 , 2 ] Other common associated lesions in patients with supravalvar mitral ring include ventricular septal defect (VSD) , patent ductus arteriosus (PDA) , atrioventricular (AV) canal defect, and tetralogy of Fallot. (medscape.com)
  • Enrollment criteria: Patients who underwent successful valve replacement or repair procedure (aortic, mitral, or tricuspid) at least 1 year prior to inclusion + within 1 month had invasively measured mean pulmonary artery pressure ≥30 mm Hg. (acc.org)
  • According to recent estimates, more than 79,000 patients are diagnosed with aortic and mitral valve disease in U.S. hospitals each year. (justia.com)
  • Management of Biventricular Assist device Implantation in patients with necrotic Pancreatitis. (uni-heidelberg.de)
  • Ninety-two patients underwent mitral valve replacement, 42 for left ventricular outflow tract obstruction and 50 for intrinsic mitral valve pathology. (scite.ai)
  • Patients undergoing mitral interventions had thinner septums (18 AE 0.4 mm vs 22 AE 0.5 mm, P (scite.ai)
  • A mitral valve intervention is a useful adjunct in patients with moderate hypertrophy. (scite.ai)
  • Mitral valved stent implantation: an overview. (musc.edu)
  • This study is the first report of 2 cases of HighLife (HighLife, Paris, France) implantation in humans. (researcher-app.com)
  • Okutucu S, Ates I, Marmagkiolis K, Kose G, Iliescu C, Cilingiroglu M. Successful WATCHMAN Device Implantation in a Patient with IVC Filter Thrombosis and Iliac Vein Occlusions. (uams.edu)
  • Pulmonary valve implantation using self-expanding tissue valve without cardiopulmonary bypass reduces operation time and blood product use. (rush.edu)
  • We report a case of redo aortic prosthesis replacement for a severe paravalvular leak (PVL) in a man operated with continuous suture technique 7 years earlier. (biomedcentral.com)
  • We report a case of redo aortic prosthesis replacement after 7 years from the operation and we discuss the role of suture technique in this case of severe paraprosthetic leak without any clearly infection signs. (biomedcentral.com)
  • Implantation of prosthetic iris device (including custom-made artificial iris). (southerncross.co.nz)
  • Prosthesis, usually heart valve, composed of biological material and whose durability depends upon the stability of the material after pretreatment, rather than regeneration by host cell ingrowth. (lookformedical.com)
  • The subannular implant was deployed through the transfemoral access, whereas the transcatheter mitral valve was released using the transapical access. (researcher-app.com)
  • But now a 15-patient study of transfemoral, transeptal TMVR - with a prosthesis designed for the mitral position and previously tested only transapically - has shown good 30-day results in that MR was essentially abolished with virtually no paravalvular leakage. (medscape.com)
  • The physiologic effect of a supravalvular mitral ring depends on the degree to which the membrane obstructs mitral valve inflow as well as the associated anatomic and functional impairment of the mitral valve. (medscape.com)
  • However, turbulence can cause a progressive increase in the supravalvar membrane or ridge, worsening mitral inflow obstruction. (medscape.com)
  • Obstruction to mitral inflow results from reduced area of the mitral valve orifice. (medscape.com)
  • Embodiments of the present disclosure are directed to a prosthesis, such as but not limited to a replacement heart valve. (justia.com)
  • Further embodiments are directed to delivery systems, devices and/or methods of use to deliver and/or controllably deploy a prosthesis, such as but not limited to a replacement heart valve, to a desired location within the body. (justia.com)
  • In some embodiments, a replacement heart valve and methods for delivering a replacement heart valve to a native heart valve, such as a mitral valve, are provided. (justia.com)
  • More than 49,000 mitral valve or aortic valve replacement procedures are performed annually in the U.S., along with a significant number of heart valve repair procedures. (justia.com)
  • Transcatheter mitral valve repair or replacement (e.g. (southerncross.co.nz)
  • If one disregards the financial considerations, predictability of the procedural outcome and certainty regarding the durability of TAVR prostheses are 2 of the main remaining restrictions to universal implementation. (ahajournals.org)
  • These developments have elevated the need for the imager to have a core understanding of the functional mitral valve anatomy. (nih.gov)
  • Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. (lookformedical.com)
  • The dental prosthesis is used for cosmetic or functional reasons, or both. (lookformedical.com)
  • Patient #1 survived at 5-months follow-up in New York Heart Association functional class II with excellent prosthesis performance. (researcher-app.com)
  • The central tenets of these principles apply to interventional imaging of transcatheter mitral valve interventions. (nih.gov)
  • Demographic profiles, echocardiogram-derived ventricular morphology and hemodynamics, operative data, and in-hospital outcomes were analyzed.Results: Of the 1559 operations, 586 were isolated septal myectomies, 522 were myectomies with mitral valve or subvalvular apparatus intervention, 422 were myectomies with another concomitant procedure, and 29 were isolated mitral valve interventions without myectomy. (scite.ai)
  • The condition characterized by an abnormal ridge of connective tissue on the atrial side of the mitral valve. (medscape.com)
  • Left atrial wall dissection, mitral valve prosthesis dehiscence and pericardial hematoma: complex findings after successful cardiac resuscitation. (uni-heidelberg.de)