AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
MinocyclineTetracyclineTetracyclinesTetracycline ResistanceAnti-Bacterial AgentsOxytetracyclineDoxycyclineMicrobial Sensitivity TestsDemeclocyclineDrug Resistance, MicrobialR FactorsChlortetracyclineMethacyclineErythromycinAcne VulgarisMicrogliaDrug Resistance, BacterialEscherichia coliConjugation, GeneticNeuroprotective AgentsDNA, BacterialDrug Resistance, Multiple, BacterialChloramphenicolUreaplasmaDNA Transposable ElementsPlasmidsBacterial ProteinsAmpicillinPenicillin ResistanceSpectinomycinStreptomycinAnti-Infective AgentsUrethritisAntiportersGenes, BacterialStaphylococcusClindamycinNeisseria gonorrhoeaeNeurogenic InflammationRifampinMatrix Metalloproteinase InhibitorsPenicillinsGonorrheaBacteroidesStaphylococcus aureusToothTooth BleachingTooth DiscolorationTooth Bleaching AgentsEncyclopedias as TopicTooth LossTooth Crown
DoxycyclineAntibioticOxytetracyclineCause permanent discolorationBacteriostaticTrimethoprimAcneAntimicrobialAbsorptionSusceptibilityFluoroquinolonesAntibacterial drugsHydrochloride tabletsBacteriaPenicillinDerivativeResistantSusceptiblePharmacieMedicinesLesionsPrescribeOrganismsGastrointestinalSolodynIncludeDosageBreast milkTreatPatientsUrineUrinaryViagraClassSide effectsAntacidsTopicalPreparations
Doxycycline23
Antibiotic9
Oxytetracycline1
Cause permanent discoloration1
  • Tetracyclines may cause permanent discoloration of teeth and slow down the growth of bones. (mayoclinic.org)
Bacteriostatic2
  • The tetracyclines are primarily bacteriostatic and are thought to exert their antimicrobial effect by the inhibition of protein synthesis. (nih.gov)
  • Tetracycline antibiotics are broad spectrum and bacteriostatic. (wedgewoodpharmacy.com)
Trimethoprim1
Acne6
  • Tetracyclines are used to treat infections and to help control acne. (mayoclinic.org)
  • Tetracyclines also treat inflammatory skin conditions, such as acne , rosacea, and perioral dermatitis. (healthline.com)
  • Minocycline is typically used to treat acne, but it can also reduce symptoms associated with mental illnesses, such as schizophrenia and depression, and it can improve decision-making. (rushlimbaugh.com)
  • Minocycline extended-release tablet (Solodyn) is only used to treat acne. (medlineplus.gov)
  • Minocycline topical foam is used to treat moderate to severe acne vulgaris. (drugs.com)
  • Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of minocycline topical foam to treat acne vulgaris in children 9 years of age and older. (drugs.com)
Antimicrobial2
  • The tetracyclines, including minocycline, have similar antimicrobial spectra of activity against a wide range of gram-positive and gram-negative organisms. (nih.gov)
  • Additionally, resistance can be readily induced in vitro in B. anthracis to a variety of antimicrobial classes including fluoroquinolones, tetracyclines, macrolides, penicillins, and other -lactams ( 8, 13- 16 ). (cdc.gov)
Absorption2
  • Intestinal absorption of tetracyclines is greatly diminished in lactating infants due to the formation of non-absorbable chelates with milk calcium (Pfizer 2015, Sandoz 2013, Mitrano 2009, Chin 2001). (e-lactancia.org)
  • Minocycline is well-absorbed after oral administration, and its absorption is minimally affected by the presence of food in the stomach. (wedgewoodpharmacy.com)
Susceptibility3
  • Because many strains of the following gram-positive microorganisms have been shown to be resistant to tetracyclines, culture and susceptibility testing are especially recommended. (nih.gov)
  • Susceptibility testing should be performed with tetracycline since it predicts susceptibility to minocycline. (nih.gov)
  • Common genomic determinants defined most strains' phenotypic, reduced susceptibility to current and historic antibiotics (e.g. bla (TEM) plasmid for penicillin, tetM plasmid for tetracycline, gyrA for ciprofloxacin, 23S rRNA and/or mosaic mtr operon for azithromycin, and mosaic penA for cefixime and ceftriaxone). (cdc.gov)
Fluoroquinolones1
  • Treatment of cellulitis caused by uncommon organisms, such as Vibrio species or gram-negative bacteria, should be individualized (eg, tetracyclines, fluoroquinolones or aminoglycosides for Vibrio infection). (medscape.com)
Antibacterial drugs1
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of minocycline hydrochloride tablets and other antibacterial drugs, minocycline hydrochloride tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
Hydrochloride tablets3
  • Minocycline hydrochloride tablets for oral administration contain minocycline HCl equivalent to 50 mg, 75 mg or 100 mg of minocycline. (nih.gov)
  • Minocycline Hydrochloride Tablets, 50 mg contains FD&C Yellow No. 5 (Tartrazine) as color additive. (nih.gov)
  • Minocycline hydrochloride tablets are rapidly absorbed from the gastrointestinal tract following oral administration. (nih.gov)
Bacteria1
  • Tetracyclines have a wide spectrum of both gram-negative and gram-positive bacteria, including spirochetes and A.a - both of which are major players in periodontitis. (dentistryiq.com)
Penicillin1
  • When penicillin is contraindicated, tetracyclines are alternative drugs in the treatment of infections caused by the cited microorganisms. (nih.gov)
Derivative1
Resistant2
  • Tetracyclines are interchangeable for most indications, although minocycline has been most studied for methicillin-resistant S. aureus infections. (msdmanuals.com)
  • A. baumannii in our hospital were highly resistant to all antibiotics, including tigecycline, except for minocycline and colistin which are considered the last resort treatment for multidrug-resistant A. baumannii . (who.int)
Susceptible4
  • Tetracycline antibiotics should not be used for streptococcal diseases unless the organism has been demonstrated to be susceptible. (nih.gov)
  • Minocycline is used in dogs to treat susceptible bacterial infections and infections caused by Rickettsia, Canine ehrlichiosis (anaplasmosis), Toxoplasma, Borrelia burgdorferi (Lyme disease), Leptospirosis, and Neorickettsia helminthoeca (salmon poisoning). (wedgewoodpharmacy.com)
  • Minocycline is used in cats to treat susceptible bacterial infections and infections caused by a number of other organisms including Bartonella, Mycoplasma, Dermatophilus, and Mycobacteria. (wedgewoodpharmacy.com)
  • Minocycline is used in horses to treat susceptible bacterial infections and tick-borne diseases such as Ehrlichia, Anaplasma, and Borrelia burgdorferi (Lyme disease). (wedgewoodpharmacy.com)
Pharmacie14
Medicines1
Lesions1
Prescribe1
Organisms2
  • minocycline was more active in vitro against both organisms. (bmj.com)
  • Cross-resistance of these organisms to tetracyclines is common. (nih.gov)
Gastrointestinal1
  • Tetracyclines commonly have gastrointestinal side effects, like upset stomach and nausea. (clevelandclinic.org)
Solodyn1
  • Minocycline comes as a regular capsule, a pellet-filled capsule, and an extended-release tablet (Solodyn) to take by mouth. (medlineplus.gov)
Include1
  • Possible adverse effects of minocycline include drug hypersensitivity syndrome, autoimmune reactions, and dizziness and headache. (healthline.com)
Dosage1
  • In previous studies with other minocycline dosage forms, the minocycline serum half-life ranged from 11 to 16 hours in 7 patients with hepatic dysfunction, and from 18 to 69 hours in 5 patients with renal dysfunction. (nih.gov)
Breast milk2
Treat8
  • Tetracyclines are a group of antibiotics with anti-inflammatory properties that can treat several bacterial infections. (healthline.com)
  • Minocycline is also used to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). (medlineplus.gov)
  • Minocycline is also sometimes used to treat rheumatoid arthritis (a condition in which the body attacks its own joints, causing pain, swelling, and loss of function). (medlineplus.gov)
  • The most common antibiotics used to treat ehrlichiosis belong to the tetracycline family of drugs. (petplace.com)
  • Tetracyclines are a class of antibiotics that treat several kinds of bacterial infections. (clevelandclinic.org)
  • What conditions do tetracyclines treat? (clevelandclinic.org)
  • Tetracyclines can treat several kinds of bacterial infections. (clevelandclinic.org)
  • Tetracycline antibiotics can treat a broad range of bacterial infections. (clevelandclinic.org)
Patients2
  • The investigators are now conducting a phase I clinical trial to determine whether minocycline treatment is safe in human patients with subarachnoid hemorrhage and whether it reduces MMP-9 levels in the spinal fluid and blood. (wustl.edu)
  • If the trial is successful, the team will conduct a phase II study to look not only at safety and MMP-9 levels but also at whether the incidence of vasospasm is reduced in patients receiving minocycline. (wustl.edu)
Urine2
  • Minocycline may be used in animals with decreased kidney function because it is extensively metabolized via the liver, and then primarily excreted as inactive metabolites in the feces and urine. (wedgewoodpharmacy.com)
  • Tetracycline and minocycline are excreted primarily in urine. (msdmanuals.com)
Urinary1
Viagra4
Class1
Side effects3
Antacids1
  • thus, tetracyclines cannot be taken with preparations containing these substances (eg, antacids, many vitamin and mineral supplements). (msdmanuals.com)
Topical1
  • Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of minocycline topical foam in the elderly. (drugs.com)
Preparations1