Osteoporosis and osteomalaciaHypophosphatemiaRickets in children and osteomalaciaPhosphorusAdultsSoftening of the bonesProximal renal tubularHypophosphatemic ricketsBonesRenal tubular dysfunctionFanconiDeficiencyMetabolic Bone DiseasesMineralizationAdultPhosphateOsteopeniaSupplementationClinicalFractureParaneoplasticTumorIncrease in boneDiagnosisMetabolismVitamin and mineralTraceCalcium supplementChronicIntakeBone and Mineral ResearchLackAbundantFindingsVitamins and mineralsDepletionSupplementsEssentialMagnesiumDietsFracturesTreatmentAmountsComparative studyBodyPatientScanDecreaseMatrixResearch
Osteoporosis and osteomalacia6
- Vitamin D treatment in osteoporosis and osteomalacia. (creighton.edu)
- The term is used primarily to indicate calcium depletion of bone in such conditions as osteoporosis and osteomalacia. (wordinfo.info)
- Osteoporosis and Osteomalacia are two physical conditions attributed to human bone weakness. (womstreet.com)
- How do you detect the two physical conditions Osteoporosis and Osteomalacia resulting from less or more production of calcium responsible for bone diseases? (womstreet.com)
- As we age, our bones become lower in calcium, increasing risks for osteoporosis and osteomalacia (softening of the bones). (umcommunities.org)
- Osteoporosis and osteomalacia both manifest as reduced apparent bone mineral density. (gitlab.io)
Hypophosphatemia7
- Oncogenic osteomalacia, also known as oncogenic hypophosphatemic osteomalacia, is an uncommon disorder resulting in increased renal phosphate excretion, hypophosphatemia and osteomalacia. (wikipedia.org)
- If there is inappropriately high urine phosphate (phosphaturia) in the setting of low serum phosphate (hypophosphatemia), there should be a high suspicion for tumor-induced osteomalacia. (wikipedia.org)
- Tumor-induced osteomalacia (TIO) is a rare, acquired paraneoplastic disorder characterized by a renal phosphate leak leading to hypophosphatemia and deranged bone turnover. (hindawi.com)
- Lack of mature collagen-links is associated with osteomalacia in patients with X-linked hypophosphatemia. (mpg.de)
- Retrieval of case reports was based on Pubmed, CNKI, Wan Fang and VIP databases using the key words adefovir dipivoxil, hypophosphatemia, osteomalacia and Fanconi syndrome. (biomedcentral.com)
- Finally, this case was diagnosed by a multidisciplinary clinic as severe hypophosphatemia osteomalacia and renal Fanconi syndrome induced by low-dose ADV. (biomedcentral.com)
- Investigations showed features of renal tubular acidosis, hypophosphatemia and raised alkaline phosphatase that were suggestive of osteomalacia. (bioscientifica.com)
Rickets in children and osteomalacia2
- However, its deficiency can cause rickets in children and osteomalacia in adults. (organicfacts.net)
- The causes rickets in children and osteomalacia exclusion criteria were: history of fracture in adults [ 1 ]. (who.int)
Phosphorus7
- Phosphorus is an essential mineral found in many foods. (medlineplus.gov)
- In the diet and body, phosphorus usually binds to other minerals in the form of phosphate salts. (medlineplus.gov)
- Phosphorus, an essential mineral, is naturally present in many foods and available as a dietary supplement. (nih.gov)
- Phosphorus and calcium are interrelated because hormones, such as vitamin D and parathyroid hormone (PTH), regulate the metabolism of both minerals. (nih.gov)
- The combination of high phosphorus intakes with low calcium intakes increases serum PTH levels, but evidence is mixed on whether the increased hormone levels decrease bone mineral density [ 2 , 4-6 ]. (nih.gov)
- Calcium and phosphorus, which are minerals, are incorporated into bones to make them strong and dense (a process called mineralization). (msdmanuals.com)
- Targeted resequencing of phosphorus metabolism?related genes in 86 patients with hypophosphatemic rickets/osteomalacia. (cdc.gov)
Adults8
- Osteomalacia is most often found in adults. (organicfacts.net)
- Findings of rickets and osteomalacia occur in children, and findings of osteomalacia and secondary hyperparathyroidism occur in adults. (medscape.com)
- Adults may present with findings of osteomalacia, while children typically show growth retardation. (medscape.com)
- Renal osteodystrophy causes rachitic and some osteomalacic changes in the child and osteomalacia and secondary hyperparathyroidism in adults. (medscape.com)
- Vitamin D3 - D3 improves overall health, helps prevent or fight osteoporosis, and can prevent rickets in children or osteomalacia in adults. (cybervitamins.com)
- In adults, vitamin D deficiency causes osteomalacia, a softening of the bones associated with defective mineralization that results in bone pain, muscle weakness, and increased risk of bone deformation and fracture. (sciencedaily.com)
- Because not enough calcium and phosphate are available to maintain healthy bones, vitamin D deficiency may result in a bone disorder called rickets in children or osteomalacia in adults. (msdmanuals.com)
- Deficiency may result in rickets in lambs and osteomalacia in adults. (sheepfarm.in)
Softening of the bones2
- Rickets (osteomalacia) is a softening of the bones that leads to fractures and deformity. (mpkb.org)
- Adult deficiency leads to osteomalacia (softening of the bones). (vitaminpharmacy.com)
Proximal renal tubular2
- Various studies have reported that adefovir dipivoxil (ADV) can cause proximal renal tubular complex dysfunction, hypophosphatemic osteomalacia (HO) and even Fanconi syndrome since it was first used in the long-term treatment of chronic hepatitis B in 2002 [ 3 ]. (biomedcentral.com)
- Tenofovir-induced osteomalacia secondary to proximal renal tubular dysfunction is not an uncommon complication known to occur. (bioscientifica.com)
Hypophosphatemic rickets1
- Serum chemistries are identical in tumor-induced osteomalacia, X-linked hypophosphatemic rickets (XHR) and autosomal dominant hypophosphatemic rickets (ADHR). (wikipedia.org)
Bones9
- The body may generate other hormones to encourage the release of phosphate and calcium from the bones if the levels of these minerals in the blood become very low. (organicfacts.net)
- Osteomalacia means soft bones, and the disease of the same name refers to there being an issue with bones being weak or brittle. (organicfacts.net)
- The collagen fibers found in bones are covered by minerals. (organicfacts.net)
- A reduction of bone mineral density, that is, of the amount of matter per cubic centimeter of bones. (mcw.edu)
- Boron - This mineral works in conjunction with calcium and magnesium to build strong bones and teeth. (cybervitamins.com)
- Provides important minerals for strong teeth and bones. (cybervitamins.com)
- In osteomalacia, the body does not incorporate enough calcium and other minerals into bones, resulting in weak bones. (msdmanuals.com)
- Calcium is a mineral that is an essential part of bones and teeth. (globalcalcium.com)
- When your body produces the right portions of minerals, the bones are strengthened. (womstreet.com)
Renal tubular dysfunction1
- Adefovir dipivoxil (ADV)-induced renal tubular dysfunction and hypophosphatemic osteomalacia (HO) have been given great consideration in the past few years. (biomedcentral.com)
Fanconi3
- Based on the changes in the patient's laboratory markers and the results of emission computed tomography and other radiographic findings, adefovir-induced hypophosphatemic osteomalacia due to acquired renal Fanconi syndrome was suspected by the clinical pharmacist. (biomedcentral.com)
- Fanconi syndrome with osteomalacia can develop in patients with chronic hepatitis B infection being treated with adefovir at a conventional low dosage of 10 mg/day. (biomedcentral.com)
- The genetic polymorphisms of XPR1 and SCL34A3 are associated with Fanconi syndrome in Chinese patients of tumor-induced osteomalacia. (cdc.gov)
Deficiency5
- The diseases caused by vitamin D deficiency are osteomalacia and rickets. (organicfacts.net)
- Fluoride could cause a calcium deficiency osteomalacia. (fluoridealert.org)
- Due to these complex interactions, an excess or deficiency of one mineral can impair the absorption and utilization of others. (thehorse.com)
- Mineral supplementation in diet is essential to prevent this deficiency. (sheepfarm.in)
- Calcium deficiency also is related to osteomalacia and may also be an important factor in the pathogenesis of several diseases such as hypertension and colon cancer. (bvsalud.org)
Metabolic Bone Diseases1
- The topics covered by this journal include bone and mineral metabolism, the anatomy and physiology of bone, diagnostic densitometry, osteoporotic fracture, metabolic bone diseases (osteoporosis, osteomalacia/rickets, osteopetrosis, renal osteodystropathy etc.), clinical trials, epidemiology and bone and muscle interaction. (scimagojr.com)
Mineralization3
- Osteomalacia is characterized by incomplete mineralization of normal osteoid tissue following closure of the growth plates. (medscape.com)
- When insufficient calcium and vitamin D is available to mineralize the osteoid, the bone develops mineralization defects that can both weaken the bone and lead to clinical osteomalacia . (fluoridealert.org)
- When osteomalacia was observed in initial trials with fluoride, the mineralization defect was prevented by supplementation with calcium and vitamin D. An increasing number of studies have, however, found indications that mineralization defects may develop in spite of supplementation. (fluoridealert.org)
Adult3
- Rickets and osteomalacia are different manifestations of the same underlying pathologic process, depending on whether the patient is a child or an adult, respectively. (medscape.com)
- Adult osteomalacia (rickets) pain in an individual relieved by vitamin D, etc. (vitamindwiki.com)
- Tumour-induced osteomalacia should be suspected in the adult presenting with new-onset hypophosphataemia, elevated FGF-23 levels and isolated renal phosphate wasting. (scienceopen.com)
Phosphate1
- This tumor may cause tumor-induced osteomalacia, a paraneoplastic syndrome, by the secretion of FGF23, which has phosphaturic activity (by inhibition of renal tubular reabsorption of phosphate and renal conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D). The paraneoplastic effects can be debilitating and are only reversed on discovery and surgical resection of the tumor. (wikipedia.org)
Osteopenia1
- Osteopenia is caused by less mineral intake responsible for common fractures. (womstreet.com)
Supplementation1
- Much of this evidence has accrued from attempts to treat human osteoporosis by means of high doses of fluoride… If the calcium insufficiency is not corrected, fluoride supplementation can induce osteomalacia… Kyle et al. (fluoridealert.org)
Clinical4
- Antiresorptive therapy should be avoided in osteomalacia due to the risk of clinical and radiographic deterioration. (scienceopen.com)
- 15 micromol/L). Although the clinical presentation of the patients varied, all 4 had an unexpectedly elevated spine bone mineral density that was proportionately higher than the bone mineral density at the hip. (fluoridealert.org)
- Osteomalacia induced by long-term low-dose adefovir dipivoxil: Clinical characteristics and genetic predictors. (cdc.gov)
- Follow-Up of Adefovir Dipivoxil Induced Osteomalacia: Clinical Characteristics and Genetic Predictors. (cdc.gov)
Fracture4
- Decreases in bone mineral density (BMD): Consider assessment of BMD in patients with a history of pathologic fracture or other risk factors for osteoporosis or bone loss. (nih.gov)
- Diagnosis is based on a history of prior fragility fracture or low bone mineral density, which is defined as a T-score ≤-2.5. (bmj.com)
- While treatments with vitamin D and calcium supplements are effective, success has been achieved with only modest increases in bone mineral density, suggesting other factors also play a role in reducing fracture risks. (sciencedaily.com)
- The Contribution of Deleterious Rare Alleles in ENPP1 and Osteomalacia Causative Genes to Atypical Femoral Fracture. (cdc.gov)
Paraneoplastic3
- Tumor-induced osteomalacia is usually referred to as a paraneoplastic phenomenon, however, the tumors are usually benign and the symptomatology is due to osteomalacia or rickets. (wikipedia.org)
- Tumor-induced osteomalacia (TIO) is a rare and fascinating paraneoplastic syndrome in which patients present with bone pain, fractures, and muscle weakness. (scienceopen.com)
- Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by tumoral production of fibroblast growth factor 23 (FGF23). (scienceopen.com)
Tumor2
- A negative family history can be useful in distinguishing tumor induced osteomalacia from XHR and ADHR. (wikipedia.org)
- FGF-23 levels were significantly increased, and total body magnetic resonance imaging (MRI) revealed a tumor mass located at the distal tibia leading to the diagnosis of tumor-induced osteomalacia (TIO). (hindawi.com)
Increase in bone1
- The main symptoms of osteomalacia are an increase in bone fractures, a waddling walk, and muscle weakness. (organicfacts.net)
Diagnosis1
- Tumour-induced osteomalacia is a difficult diagnosis as the tumour is often small and slow growing. (scienceopen.com)
Metabolism4
- Minerals are essential for life, growth, and metabolism. (thehorse.com)
- Journal of bone and mineral metabolism 2004 22 (1): 39-43. (cdc.gov)
- Bone mineral density and calcium metabolism in adolescents with beta-thalassemia major. (cdc.gov)
- Journal of bone and mineral metabolism 2017 12 36 (6): 723-733. (cdc.gov)
Vitamin and mineral2
- Browse our exceptional and unique line of Multi Vitamin and Mineral products from the leading producers of organic supplements. (live-live.com)
- They are intended to increase the vitamin and mineral intake of infants and young children. (bvsalud.org)
Trace2
- Our bodies need a steady stream of minerals, many in trace amounts, to function properly. (mighty-90.com)
- improved solubility, neutral pH and low trace minerals. (globalcalcium.com)
Calcium supplement1
- To prevent osteomalacia, the calcium supplement must be "administered concurrently" with fluoride (Riggs and Jowsey 1972). (fluoridealert.org)
Chronic1
- Furthermore, the updated treatment guidelines for chronic HBV management specified that patients had decreased renal function and bone mineral density for a long-term treatment with certain anti-HBV medications [ 2 ]. (biomedcentral.com)
Intake2
- Osteomalacia may be observed in fluorotic individuals with a reduced or suboptimal intake of calcium. (fluoridealert.org)
- Salt is sometimes used to limit the intake of free choice mineral mixes. (premier1supplies.com)
Bone and Mineral Research1
- In Journal of Bone and Mineral Research, 15 , S. S338 - S338. (mpg.de)
Lack1
- Lack of association between vitamin D receptor gene polymorphism (BsmI) and osteomalacia. (cdc.gov)
Abundant2
- Despite abundant sunlight, rickets and osteomalacia are prevalent in South Asian countries. (mpkb.org)
- Calcium is also the most abundant mineral in the human body. (vitaminpharmacy.com)
Findings1
- The histopathologic findings of renal osteodystrophy are commonly used to further classify the condition into high bone turnover states, such as osteitis fibrosa and hyperparathyroidism, and low bone turnover states, such as adynamic bone disease or heavy metal-induced osteomalacia. (medscape.com)
Vitamins and minerals2
- Getting the correct amount of the right vitamins and minerals in our diets is important at any age, but needs can change as we age. (umcommunities.org)
- It's best to get your vitamins and minerals from a healthy food source because they contain additional dietary essentials like fiber. (umcommunities.org)
Depletion1
- Young sheep grazing on drought-stricken pastures can suffer serious depletion of reserves of minerals and vitamins. (sheepfarm.in)
Supplements3
- In order for it to operate at its maximum efficiency, there are a certain number of vitamins, nutrients, and minerals that you have to consume either in foods or through supplements. (organicfacts.net)
- In addition, some calcium supplements are combined with vitamins and other minerals. (globalcalcium.com)
- Before starting any vitamin or mineral supplements, you should speak to your doctor to determine a plan that fits your needs, won't adversely affect any medical conditions you may have and doesn't affect any prescription medications you may be taking. (umcommunities.org)
Essential5
- Sixteen (16) minerals have been classified as nutritionally essential in sheep diets. (premier1supplies.com)
- Magnesium - This essential mineral is the fifth most common substance in the entire universe, and plays a vital role in your body. (cybervitamins.com)
- The minerals listed below have been identified by Dr. Wallach as essential and comprise 60 of the 90 essential nutrients . (mighty-90.com)
- It increases the survival rate of newborns, and, according to Professor Gerhard Schrauzer, former professor of chemistry at UCSD, is "probably an essential mineral for human nutrition. (mighty-90.com)
- Calcium is a major mineral essential for proper nutrition. (vitaminpharmacy.com)
Magnesium2
- Magnesium is a mineral that is important for normal bone structure in the body. (globalcalcium.com)
- Since magnesium works closely with calcium, it is important to have an appropriate ratio of both minerals in order for them to be effective. (globalcalcium.com)
Diets1
- Learn about the delicate balance between two key minerals in horses' diets. (thehorse.com)
Fractures1
- The health benefits of vitamin D, also known as calciferol, include curing rickets, the treatment of osteomalacia, protection against peripheral arterial disease (PAD), slowing the progression of cancer, preventing bone fractures, and treating rachitic rosary. (organicfacts.net)
Treatment3
- Tenofovir-induced hypophosphatemic osteomalacia: how do bone mineral density, trabecular bone score and proximal hip geometry change with treatment? (bioscientifica.com)
- Tenofovir-induced osteomalacia is encountered in individuals on prolonged treatment with tenofovir. (bioscientifica.com)
- Treatment results in a significant improvement in bone mineral density, trabecular bone score and hip geometric parameters. (bioscientifica.com)
Amounts2
- Macro-minerals are required in large amounts. (premier1supplies.com)
- Each compound contains varying amounts of the mineral calcium - calcium carbonate (40% elemental calcium) and calcium citrate (21% elemental calcium). (cybervitamins.com)
Comparative study1
- Shape and orientation of mineral crystals in mineralized tissues a comparative study by SAXS. (mpg.de)
Body3
- In the context of nutrition, minerals contribute to hundreds of vital functions in the body-everything from brain activity to heartbeat. (thehorse.com)
- The body is constantly regenerating its bone tissue, thus it is important to consume an adequate amount of this mineral daily. (globalcalcium.com)
- This mineral is important for your red blood cells, the cells that carry oxygen throughout your body. (umcommunities.org)
Patient1
- The patient was subsequently diagnosed with two separate conditions, namely cardiac amyloid light-chain (AL) amyloidosis and FGF-23-related hypophosphataemia, likely due to tumour-induced osteomalacia. (scienceopen.com)
Scan2
- She was initially diagnosed with osteoporosis based on her dual-energy X-ray absorptiometry (DXA) scan bone mineral density (BMD) T-scores and started on denosumab therapy. (scienceopen.com)
- They will also probably recommend a Dual-Energy X-ray Absorptiometry (DEXA or DXA) scan, also called a bone mineral density scan. (bannerhealth.com)
Decrease1
- A decrease in the mineral content of a tissue. (wordinfo.info)
Matrix3
- The strength of a bone depends upon the rich mineral coating over the collagen matrix. (organicfacts.net)
- The matrix must also be strong to avoid Osteomalacia condition. (womstreet.com)
- The differentiating factor is mineral per volume of matrix. (gitlab.io)
Research1
- Two South Asian women's groups were recruited to receive information about osteomalacia either by interactive DVD or an Arthritis Research UK leaflet. (vitamindwiki.com)