• Oxytalan fibers contain the microfibrillar protein fibrillin but no elastin. (skintypesolutions.com)
  • 2022). Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development. (mcgill.ca)
  • Co-localization of microfibrils and elastin fibres was examined by dual immunostaining of fibrillin-1 and elastin. (ox.ac.uk)
  • Fibrillin-1- containing microfibrils provide long-term force bearing structural support. (affbiotech.com)
  • Elastin and fibrillin-1 were identified as prominent components of paraspinal blood vessels, and posterior longitudinal ligament in the human fetal spine and outer annulus fibrosus of the fetal intervertebral disc. (cardiff.ac.uk)
  • Elastin, fibrillin-1 and perlecan were co-localized in the intima and media of small blood vessels in the synovium and in human fetal paraspinal blood vessels. (cardiff.ac.uk)
  • When the signal stops, the muscle fibers rearrange and the contraction stops, the muscle relaxes. (vitalscend.com)
  • It has a mesodermal origin and is formed by elongated cells called muscle fibers, which contain actin and myosin and whose functional characteristics are excitability, conductivity and contractility. (agrocorrn.com)
  • Made up of many smaller protein fibers, a muscle can contract and produce force. (vitalscend.com)
  • In the inner annulus fibrosus, the microfibrils were predominantly visible as a filamentous mesh network, both in the interterritorial matrix and also around the cells. (ox.ac.uk)
  • Elastin is a resilient connective tissue protein found in the ECM of most vertebrate tissues, and it is an important part in the interstitium of tissues that undergo repeated physical deformations in the human body (Swee et al. (github.io)
  • In the outer annulus fibrosus (OAF), abundant microfibrils organized in bundles were mainly distributed in the interterritorial matrix. (ox.ac.uk)
  • In addition, the microfibril bundles were orientated parallel to each other and co-localized highly with elastin fibres. (ox.ac.uk)
  • The research themes rank around molecular mechanisms matrix proteins and fibers exert in disorders affecting blood vessels, bone, skin and adipose tissue. (mcgill.ca)
  • Elevation of the dermal-epidermal junction maybe functionally related to the positive effect of the HA to the collagen fiber alignment. (suisselle.com)
  • This may help us to understand the interactions which are expected to occur in vivo between the tropoelastin and perlecan to facilitate the deposition of elastin and formation of elastic microfibrils in situ and would be consistent with the observed distributions of these components in a number of connective tissues. (cardiff.ac.uk)
  • Stretch marks occur when the skin's collagen and elastin fibers are stretched, like when a person grows or gains weight rapidly. (healthline.com)
  • FBN2 silencing recapitulates hypoxic conditions and induces elastic fiber impairment in human dermal fibroblasts. (mcgill.ca)
  • Not only do microfibrils provide structural integrity of specific organ systems, but they also provide a scaffold for elastogenesis in elastic tissues. (github.io)
  • This paper presents specialized strain energy functions for the W aniso part of this additive split, in the form of W aniso (I 4 ) or W aniso (I 4 , I 6 ) for one or two fiber families, respectively, accounting for the deformation and contribution of the collagen fibers' network. (asme.org)
  • Microfibrils, elastin fibres and collagen fibres in the human intervertebral disc and bovine tail disc. (ox.ac.uk)
  • The distribution of microfibrils was studied immunohistochemically in intervertebral discs taken from young normal human surgical cases and from the bovine tail. (ox.ac.uk)
  • abstract = "Elastic fiber fragmentation (EFF) is a hallmark of aortic valve disease (AVD), and neovascularization has been identified as a late finding related to inflammation. (elsevierpure.com)
  • A distinct pattern of elastic fiber components surrounded early-onset AVD neovessels, including increased emilin-1 and decreased fibulin-5. (elsevierpure.com)
  • Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. (thermofisher.com)
  • Electrostatic interactions through the heparan sulfate chains of perlecan and core protein mediated the interactions with tropoelastin, and were both important in the coacervation of tropoelastin and deposition of elastin onto perlecan immobilized on the chip surface. (cardiff.ac.uk)
  • The ultrastructural and histophotometric study of elastic and collagen fibers in type II Ehlers-Danlos syndrome and subclinical forms. (nih.gov)