Microbiota bacteria. Medical search. Frequent questions

BACKGROUND Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection (rCDI) in adults and children, but donor stool samples are currently screened for only a limited number of potential pathogens. (jci.org)
Researchers at Memorial Sloan Kettering Cancer Center have shown that autologous fecal microbiota transplantation (auto-FMT) is a safe and effective way to help replenish beneficial gut bacteria in cancer patients who require intense antibiotics during allogenic hematopoietic stem cell transplantation. (sbbs-soc.com)
A Spanish study has shown that faecal microbiota transplantation can help to confer partial protection against African Swine Fever virus (ASFv). (pigprogress.net)
Does a microbiota transplantation make a difference? (pigprogress.net)
Explaining the "why" behind the research, they referred to the fact that a faecal microbiota transplantation has proven beneficial in the treatment of human and animal viral diseases, chronic liver diseases, ulcerative colitis and to fight multi-resistant Clostridium difficile infections in humans. (pigprogress.net)
No differences were observed after intramuscular challenging with E75, a virulent ASFv strain, independently of the faecal microbiota transplantation. (pigprogress.net)
At UMassMemorial Medical School, we are evaluating the effectiveness of a promising new approach, Fecal Microbiota Transplantation, to cure Clostridium difficile infections. (umassmed.edu)
Fecal microbiota transplantation (FMT) from healthy individuals to patients with CDI has been used increasingly over the past several decades to restore healthy flora in the gut, thus breaking the cycle of recurrent CDI. (pharmacytimes.com)
Researchers demonstrated that the intestinal microbiota development can be restored by postnatal, orally-delivered transplantation of maternal fecal microbiota. (helsinki.fi)
In the recently reported study, researchers of mainly the University of Helsinki evaluated whether the disturbed intestinal microbiota development could be restored in term Cesarean section infants by postnatal, orally-delivered maternal fecal microbiota transplantation (FMT). (helsinki.fi)
Reference: Korpela K., Helve O., Kolho K-L., Saisto T., Skogberg K., Dikareva E., Stefanovic V., Salonen A., Andersson S., de Vos W. Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept. (helsinki.fi)
Researchers have shown that autologous fecal microbiota transplantation may be a safe and effective way to help replenish beneficial gut bacteria in patients with cancer who require intense antibiotics during allogeneic hematopoietic stem cell transplantation. (ascopost.com)
When it comes to the causal relationship between the gut microbiome and obesity, the strongest available evidence has emerged from rodent models where it has been demonstrated that fecal microbiota transplantation can transfer the obese phenotype and that the gut microbiome plays a fundamental role in harvesting energy from the diet. (medscape.com)
Fecal microbiota transplantation, also known as FMT, is a new way to replenish 'good' bacteria in some cancer patients . (medlineplus.gov)

However, in the absence of Myd88 or under conditions of antibiotic-induced dysbiosis, non-invasive bacteria were trafficked to the MLNs in a CCR7-dependent manner, and induced both T-cell responses and IgA production. (nih.gov)
An array of chronic inflammatory diseases are associated with dysbiosis in the intestinal microbiota and a breakdown in the normally mutually beneficial host-microbiota relationship. (nature.com)
Dysbiosis in gut microbiota has been implicated in several lung diseases, including allergy, asthma and cystic fibrosis. (frontiersin.org)
Dysbiosis within this homeostasis in the gut microbiota is associated with a multitude of health conditions affecting not only gut, but also distal organs like mouth, lung, brain, liver, vagina, etc. (frontiersin.org)
Strain dropout experiments revealed that the lack of RBOHD unlocks the pathogenicity of individual microbiota members driving dysbiosis in rbohD knockout plants. (nature.com)
Fig. 3: The plant mutant rbohD shows a dysbiosis phenotype and assembles a microbiota enriched in Gammaproteobacteria. (nature.com)
1,2 Accumulating evidence suggests that dysbiosis, defined as a perturbation in the intestinal microbiota composition characterized by reduced richness and diversity, is implicated in development of and recovery from CDI. (pharmacytimes.com)

A deeper understanding of the gut microbiome which comprises of all the genetic material within the gut microbiota and its role in respiratory disorders is likely to help in designing appropriate probiotic cocktails for therapeutic applications. (frontiersin.org)
Placental microbiome List of bacterial vaginosis microbiota List of microbiota species of the lower reproductive tract of women Lung microbiota Gut microbiota Skin flora https://www.wikidata.org/wiki/Q1591401 List of skeletal muscles of the human body List of proteins in the human body List of organs of the human body List of distinct cell types in the adult human body Abbott, Alison (2016-01-08). (wikipedia.org)
The composition of pancreatic tumor microbiome, which is impacted by the gut microbiota, could modulate the patient's immune response and the growth of adenocarcinoma. (biocodexmicrobiotainstitute.com)
The findings suggest that newborns at risk for Type 1 diabetes because their microbiome -- the trillions of beneficial microorganisms in and on our bodies -- were disturbed can have the condition reversed by transplanting fecal microbiota from their mother into their gastrointestinal tract after the antibiotic course has been completed. (sciencedaily.com)
Bacteria that make up the gut microbiome produce vitamins and short-chain fatty acids while helping to digest food into nutrients our bodies can use. (serva-ts.com)
Gut bacteria is made up of beneficial microbial colonies that exist in the digestive tract and are known collectively as the microbiome . (serva-ts.com)
You may have heard the terms "gut microbiota" and "microbiome" and wondered what they mean and why they matter. (mskcc.org)
What is the microbiota, and how is it different from the microbiome? (mskcc.org)
All humans have a microbiome comprising thousands of microorganisms, such as bacteria, fungi, and viruses, which co-exist naturally in the body. (medicalnewstoday.com)
Rockefeller University researchers were already interested in the small molecules that human-associated bacteria produce and their effect on the body's host cells and coinhabiting organisms of the microbiome. (medicalnewstoday.com)
Although thousands of different bacteria form the human microbiome, the researchers chose to study a diverse, representative group of 50 bacteria. (medicalnewstoday.com)
Infection occurs when antibiotics disrupt the normal microbiome in the colon, allowing Clostridium difficile bacteria to take over. (umassmed.edu)
Increasing evidence support that IBD patients exhibit an altered microbiome (harmful bacteria outnumbering the beneficial ones), which can be the lost piece of the puzzle. (umassmed.edu)
As prevention and management of rCDI has continued to present a challenge, interest has been re-ignited throughout the past decade in the application of a microbiota-based therapeutic for CDI to aid in microbiome restoration. (pharmacytimes.com)

It is important to understand the influence of gut microbiota and metabolites produced by them on the functioning of various organs within the body (Figure 1 ). (frontiersin.org)
In recent years, a mass of research has identified that gut microbiota and corresponding bacterial metabolites can target the brain through various pathways, such as nervous conduction (enteric nerve, vagus nerve, etc. (frontiersin.org)
Using animal models, scientists recently discovered that a change to the gut microbiota brought about by chronic stress can lead to depressive-like behaviors, in particular by causing a reduction in lipid metabolites (small molecules resulting from metabolism) in the blood and the brain. (pasteur.fr)
Gut microbiota and its metabolites have been shown to influence multiple physiological mechanisms related to human health. (springer.com)
SCFAs are metabolites of specific bacterial taxa of the human gut microbiota , and their production is influenced by specific foods or food supplements , mainly prebiotics , by the direct fostering of these taxa. (bvsalud.org)
Lactic acid bacteria (LAB) participating in milk fermentation naturally release and enrich the fermented dairy product with a broad range of bioactive metabolites, which has numerous roles in the intestinal health-promoting of the consumer. (biomedcentral.com)
The changes in microbiota and metabolites induced by LFM might mediate the regulation of the secretory function of goblet cells. (biomedcentral.com)
Researchers found microbiota-derived metabolites-or products made by microbes-were significantly altered in the feces of mice with endometriosis. (medicalnewstoday.com)
The research suggests studying microbiota metabolites in human stool samples may serve as a diagnostic tool for endometriosis. (medicalnewstoday.com)
Dr. Picotta, Prof. Brady, and their colleagues discovered startling aspects of the antiviral metabolites that their cohort of study bacteria produced. (medicalnewstoday.com)
Objectives Habitual diet plays a major role in shaping the composition of the gut microbiota, and also determines the repertoire of microbial metabolites that can influence the host. (bmj.com)

Finally, fecal microbiota transplants (FMT) from three types of patients (long-, short-term survival or control) were carried out in mice. (biocodexmicrobiotainstitute.com)
For people who keep getting C. diff infections, treatments such as fecal microbiota transplants (FMT) have shown promising results. (medlineplus.gov)

This diverse microbial ecosystem is composed of bacteria, viruses, fungi, protists and archaea that inhabit the skin, nose and sinuses, gastrointestinal tract (both the stomach and small intestine), oral cavity (mouth), urinary tract and genital regions. (serva-ts.com)
However, the mix of bacteria and fungi was different . (thehorse.com)
The human gut contains a diverse ecosystem of microbes: mainly bacteria, as well as viruses and fungi, termed the gut microbiota. (helsinki.fi)
The term "gut microbiota" refers to the bacteria, yeast, fungi, viruses, and bacteriophages that inhabit the human colon. (medscape.com)
Infective Endocarditis Infective endocarditis is infection of the endocardium, usually with bacteria (commonly, streptococci or staphylococci) or fungi. (msdmanuals.com)
In the microbiota analyses, they found alterations in all three domains of life (fungi, archaea, and bacteria), as well as viruses, in relation to the development of colorectal cancer. (who.int)

Bacterial virulence factors in stool DNA extracts and stool cultures were measured by quantitative PCR: Bacteroides fragilis toxin (bft), Fusobacterium adhesin A (fadA), and Escherichia coli colibactin (clbB).RESULTS Four of 11 patients demonstrated sustained acquisition of a procarcinogenic bacteria. (jci.org)
Multidrug-resistant plasmid-carrying bacteria are of particular clinical concern as they could transfer antibiotic resistance genes to other bacterial species. (amr-insights.eu)
Since mitochondria emerged from bacterial ancestors during endosymbiosis, mitochondria, and bacteria had analogous genomic characteristics, similar bioactive compounds and comparable energy metabolism pathways. (frontiersin.org)
The bacterial population in the gut, known as the gut microbiota, is the largest reservoir of bacteria in the body. (pasteur.fr)
however, its bacterial composition greatly differs from that of dental plaque microbiota, which is a dominant etiologic factor of oral diseases. (elsevierpure.com)
Their results put forward a larger diversity of bacterial species present in the tumor microbiota of patients who survived more than 5 years. (biocodexmicrobiotainstitute.com)
Moreover, the authors highlighted that each one of the two groups of patients displayed a specific intratumoral microbiota signature: presence and abundance of 3 bacterial genera ( Pseudoxanthomonas, Streptomyces, Saccharopolyspora ) and of Bacillus clausii are able to predict the survival in 97.51 to 99.17% of cases (according to the cohort). (biocodexmicrobiotainstitute.com)
The specific serotypes of the first licensed 7-valent pneumococcal vaccine are common colonizers of the upper respiratory tract of children during the first years of life, in which these serotypes generally reside as part of the nasopharyngeal microbiota (bacterial community) ( 3 ). (cdc.gov)
Perturbations of these interactive microbial structures (e.g., by environmental change or vaccinations) alter the bacterial network structures and may thereby influence the presence and containment of other microbiota members, and these alterations have effects on health and susceptibility to disease ( 13 , 14 ). (cdc.gov)
A detailed characterization of the microbiota in these mice revealed profound changes to their bacterial populations, including new microbial functions that are known to infer a propensity to obesity, diabetes and complications of these problems in both mice and humans. (eurekalert.org)
What did have a significant effect on the microbiota were two life events - one subject moved abroad, while the other had a significant bout of food poisoning which caused most pre-existing gut bacterial species to decline. (biomedcentral.com)
In the first few years of life, the bacterial microbiota within the mouth is predominantly aerobic, but, as the teeth develop, favorable sites supporting pathogenic anaerobic bacteria emerge. (medscape.com)

One of the most influencing strategies for the maintenance and modulation of gut microbiota is the oral administration of particular microbes, which are known as probiotics with a definition of "live microorganisms that when administered in adequate amounts confer a health benefit on the host" [ 11 ]. (biomedcentral.com)
Your "microbiota" is the collection of all the microbes that live on and inside your body. (mskcc.org)
These microbes include viruses, bacteria, and other microorganisms. (mskcc.org)

Immunization also resulted in decreased presence of the pneumococcal vaccine serotype and an increase in the relative abundance and presence of nonpneumococcal streptococci and anaerobic bacteria. (cdc.gov)
CONCLUSIONS: This study shows that the colonic inflammation alters the microbial balance, while β-glucan treatment increases the anaerobic bacteria and promotes colitis attenuation and elimination. (univ-lille.fr)
Overview of Anaerobic Bacteria Bacteria can be classified by their need and tolerance for oxygen: Facultative: Grow aerobically or anaerobically in the presence or absence of oxygen Microaerophilic: Require a low oxygen concentration. (msdmanuals.com)

Here we demonstrate in mice that, at steady state, the microbiota inhibits the transport of both commensal and pathogenic bacteria from the lumen to a key immune inductive site, the mesenteric lymph nodes (MLNs). (nih.gov)

The oral microbiota is related to oral sicknesses and digestive systemic sicknesses. (alliedacademies.org)
Among workers in different locations within the facility, those that worked in machine shop area had skin, nasal and oral microbiota more closely related to the microbiota present in MWF samples. (cdc.gov)

We show, in mice, that repeated injection of flagellin elicits increases in fecal anti-flagellin IgA and alterations in microbiota composition, reduces fecal flagellin concentration, prevents microbiota encroachment, protects against IL-10 deficiency-induced colitis, and ameliorates diet-induced obesity. (nature.com)
Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system, Nature Communications , December 11, 2020. (pasteur.fr)
Gut microbiota, the huge community formed by trillions of microorganisms ("whether rich and diverse or poor and limited"), has been linked to various organs and functions as well as to brain development, at least in mice, explain Campbell and Enck in "Psychobiotics" And The Science Of How Gut Bacteria Can Affect The Human Brain . (gutmicrobiotaforhealth.com)
The study compared mice that were exposed to antibiotics between days 5 and 10 of life and given a transplant of maternal microbiota up to a week later, and those that were not. (sciencedaily.com)
Next, they transferred the microbiota from mice that consumed artificial sweeteners to 'germ-free' mice - resulting in a complete transmission of the glucose intolerance into the recipient mice. (eurekalert.org)
The group even found that incubating the microbiota outside the body, together with artificial sweeteners, was sufficient to induce glucose intolerance in the sterile mice. (eurekalert.org)
Oral administration of β-glucans to mice decreased the overgrowth of aerobic bacteria and IL-1β expression while and populations increased significantly. (univ-lille.fr)
Uterine microbiota, on the other hand, did not seem to affect the progression of endometriosis in mice. (medicalnewstoday.com)
For this study, researchers elected to study microbiota-depleted mice who have been raised normally and then given broad-spectrum antibiotics. (medicalnewstoday.com)
Researchers then surgically induced endometriosis in both control and microbiota-depleted mice. (medicalnewstoday.com)
Since surgery can also trigger an inflammatory response in mice, researchers also induced endometriosis using injections in both control and microbiota-depleted mice. (medicalnewstoday.com)
Researchers then gave control mice and microbiota-depleted mice feces from mice without endometriosis and feces from mice with endometriosis. (medicalnewstoday.com)
Additionally, researchers analyzed peritoneal fluid looking for immune cell populations in control and microbiota-depleted mice to determine if altered immune cell composition was associated with reduced lesion growth in microbiota-depleted mice. (medicalnewstoday.com)
When researchers surgically induced endometriosis in both control and microbiota-depleted mice, they found lesions in control mice to be significantly larger and "more obviously fluid-filled and vascularized" than lesions in microbiota-depleted mice. (medicalnewstoday.com)
With control and microbiota-depleted mice who were given injection-based endometriosis, lesions in control mice were significantly larger and greater in number than in microbiota-depleted mice. (medicalnewstoday.com)
Researchers administered fecal matter from mice with and without endometriosis to control mice and microbiota-depleted mice who had surgically induced endometriosis. (medicalnewstoday.com)
Transplanting fecal matter from mice with endometriosis into microbiota-depleted mice resulted in typical endometriosis lesions. (medicalnewstoday.com)
RESULTS- We found that changes of gut microbiota induced by an antibiotic treatment reduced metabolic endotoxemia and the cecal content of LPS in both high-fat-fed and ob/ob mice. (diabetesjournals.org)
Early studies that compared germ-free mice and conventionally raised mice suggested that the gut microbiota may play a role in host lipid metabolism. (news-medical.net)
When the team transplanted fecal microbiota from resistant starch-treatment patients to mice fed with a high-fat high-cholesterol diet, the mice saw a significant reduction in liver weight and liver triglyceride levels and improved liver tissue grading compared with mice that received microbiota from the control group. (eurekalert.org)
For example, obesity can be transferred to germ-free mice with fecal microbiota from obese subjects, but not from lean twins. (medscape.com)
A similar transplant of the microbiota from Malawian children with kwashiorkor with a Malawian diet, however, produces weight loss in mice, accompanied by alterations in amino acid, carbohydrate and intermediate metabolism. (medscape.com)
By studying both healthy and diseased mice, the researchers found that mice suffering from Alzheimer's have a different composition of gut bacteria compared to mice that are healthy. (lu.se)
The researchers also studied Alzheimer's disease in mice that completely lacked bacteria to further test the relationship between intestinal bacteria and the disease. (lu.se)
Mice without bacteria had a significantly smaller amount of beta-amyloid plaque in the brain. (lu.se)
To clarify the link between intestinal flora and the occurrence of the disease, the researchers transferred intestinal bacteria from diseased mice to germ-free mice, and discovered that the mice developed more beta-amyloid plaques in the brain compared to if they had received bacteria from healthy mice. (lu.se)
It was striking that the mice which completely lacked bacteria developed much less plaque in the brain", says researcher Frida Fåk Hållenius, at the Food for Health Science Centre. (lu.se)

The plant microbiota consists of a multitude of microorganisms that can affect plant health and fitness. (nature.com)
From gut bacteria to skin microbiota, scientists are uncovering new insights into how the trillions of microorganisms that live in and on our bodies can affect our health and well-being. (serva-ts.com)
Prebiotics are foods that reach the gut microbiota and can be utilized by those microorganisms. (medscape.com)

Often these are due to a reduced colonization resistance against pathogens due to antibiotic-mediated killing of the protective native intestinal bacteria. (umassmed.edu)
New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease. (lu.se)

Studies have shown that the gut microbiota can affect the amount of energy that is extracted from food during digestion, which in turn can predispose individuals to obesity and the development of obesity-related illnesses such as insulin resistance and cardiovascular disease. (news-medical.net)
Recent years have shown that the gut microbiota have widespread effects on the overall functioning of the host's body. (helsinki.fi)

However, antibiotics also destroy beneficial bacteria that enhance immune function and resistance to infection. (sbbs-soc.com)
Impact of antibiotics on the gut microbiota, does it matter? (biocodexmicrobiotainstitute.com)
Antibiotics: what impact on the microbiota and on our health? (biocodexmicrobiotainstitute.com)
As for external factors, faecal transplantations and antibiotics have dramatic but temporary effects on the host microbiota [ 9 ]. (springer.com)
Killing these bacteria requires even stronger antibiotics, and unfortunately these antibiotics are becoming less effective every year. (umassmed.edu)
Although antibiotics are the standard-of-care treatment for Clostridioides difficile infection, they can cause further microbiota changes that predispose patients to recurrence. (pharmacytimes.com)
C. diff bacteria are commonly found in the environment, but people usually only get C. diff infections when they are taking antibiotics . (medlineplus.gov)

Warthog faecal microbiota may help conferring protection against ASF virus. (pigprogress.net)
The article demonstrates that a warthog faecal microbiota transplant is not harmful for domestic weaned piglets, while it modifies their gut microbiota. (pigprogress.net)
After DNA extraction, it was found that the diversity in the faecal microbiota of SPF pigs was the lowest of the groups. (pigprogress.net)
We analysed the effects of a 10-d periodic fasting on the faecal microbiota of fifteen healthy men. (nih.gov)
Faecal 16S rRNA gene amplicon sequencing showed that fasting caused a decrease in the abundance of bacteria known to degrade dietary polysaccharides such as Lachnospiraceae and Ruminococcaceae. (nih.gov)
Changes in taxa abundance were associated with serum glucose and faecal branched-chain amino acids (BCAA), suggesting that fasting-induced changes in the gut microbiota are associated with host energy metabolism. (nih.gov)
Analysis of gut bacteria showed a significant increase of lactobacilli on the ileal mucosa, specifically Lactobacillus reuteri, in the rats fed the thylakoid diet compared with rats fed the control diet, while faecal lactobacilli decreased. (lu.se)

Flagellin's impact on the microbiota is B-lymphocyte dependent and, in humans, obese subjects exhibit increased levels of fecal flagellin and reduced levels of fecal flagellin-specific IgA, relative to normal weight subjects. (nature.com)
The aim of this review is to define and characterise common fermented foods (kefir, kombucha, sauerkraut, tempeh, natto, miso, kimchi, sourdough bread), their mechanisms of action (including impact on the microbiota), and the evidence for effects on gastrointestinal health and disease in humans. (mdpi.com)

Therefore, it has been suggested that the modulation of gut microbiota could be a reliable tool to prevent metabolic and inflammatory diseases. (springer.com)

The intestinal microbiota has a critical role in immune system and metabolic homeostasis, but it must be tolerated by the host to avoid inflammatory responses that can damage the epithelial barrier separating the host from the luminal contents. (nih.gov)
Alterations in gut microbiota composition are associated with metabolic syndrome and chronic inflammatory diseases such as inflammatory bowel disease. (nature.com)
Herein, we describe that repeated systemic administration of purified flagellin elicits a robust anti-flagellin fecal IgA response that serves to reshape microbiota composition, reduces flagellin expression, and protects against experimental colitis and metabolic syndrome. (nature.com)
The gut microbial community (Gut microbiota) is known to impact metabolic functions as well as immune responses in our body. (frontiersin.org)
On the other hand, several studies suggested that diet might influence gut microbiota composition and activity thus modulating the risk of metabolic disease, i.e. obesity, insulin resistance and type 2 diabetes. (springer.com)
However, to date, there is no conclusive evidence to support this thesis, likely due to the lack of studies focusing primarily on the relationship between the composition of the gut microbiota and metabolic response. (springer.com)
We previously determined, first, that metabolic endotoxemia controls the inflammatory tone, body weight gain, and diabetes, and second, that high-fat feeding modulates gut microbiota and the plasma concentration of lipopolysaccharide (LPS), i.e., metabolic endotoxemia. (diabetesjournals.org)
Therefore, it remained to demonstrate whether changes in gut microbiota control the occurrence of metabolic diseases. (diabetesjournals.org)
RESEARCH DESIGN AND METHODS- We changed gut microbiota by means of antibiotic treatment to demonstrate, first, that changes in gut microbiota could be responsible for the control of metabolic endotoxemia, the low-grade inflammation, obesity, and type 2 diabetes and, second, to provide some mechanisms responsible for such effect. (diabetesjournals.org)
CONCLUSIONS- This new finding demonstrates that changes in gut microbiota controls metabolic endotoxemia, inflammation, and associated disorders by a mechanism that could increase intestinal permeability. (diabetesjournals.org)
It would thus be useful to develop strategies for changing gut microbiota to control, intestinal permeability, metabolic endotoxemia, and associated disorders. (diabetesjournals.org)

New research published online in Blood suggests that the diversity of bacteria in the gastrointestinal tract of patients receiving stem cell transplants may be an important predictor of their post-transplant survival. (ascopost.com)

The researchers found that auto-FMT resulted in the recovery of beneficial gut bacteria to near baseline levels within days, thus restoring patients' digestive, immune and other essential functions. (sbbs-soc.com)
The tumor microbiota seems to play a role in this survival rate, based on the numerous results published in Cell by 31 researchers-mainly Americans. (biocodexmicrobiotainstitute.com)
To understand the impact of tumor microbiota and immune system on the long-term survival rate, these researchers analyzed the composition of the microbiota of resected tumors in 68 patients with PDAC divided into two groups: 36 patients who survived more than 5 years (mean: 10.1 years) and 32 patients who died less than 5 years after the procedure (mean: 1.6 years). (biocodexmicrobiotainstitute.com)
Aug. 30, 2023 Researchers have discovered a type of gut bacteria that might help improve insulin resistance, and thus protect against the development of obesity and type-2 diabetes. (sciencedaily.com)
Next, the researchers investigated a hypothesis that the gut microbiota are involved in this phenomenon. (eurekalert.org)
The composition of their gut microbiota explained the difference: The researchers discovered two different populations of human gut bacteria - one that induced glucose intolerance when exposed to the sweeteners, the second that had no effect either way. (eurekalert.org)
Recently, researchers at Baylor College of Medicine looked at how altered gut microbiota may play a role in how endometriosis progresses. (medicalnewstoday.com)
The researchers at Baylor College of Medicine set out to show whether gut microbiota directly influences the formation and growth of endometriosis lesions. (medicalnewstoday.com)
The researchers hypothesized that antibiotic therapy possibly reduced specific gut bacteria. (medicalnewstoday.com)
Researchers found donkeys are equipped with a gut microbiota that's better at extracting energy from fiber than equine microbiotas. (thehorse.com)
Researchers from the International Agency for Research on Cancer (IARC) and partner institutions have uncovered alterations in the gut microbiota that are associated with colorectal cancer and are present in biological samples from eight distinct geographical cohorts from around the world. (who.int)
The researchers will continue to study the role of bacteria in the development of Alzheimer's disease, and test entirely new types of preventive and therapeutic strategies based on the modulation of the gut microbiota through diet and new types of probiotics. (lu.se)

The skin microbiota: why is it so important? (biocodexmicrobiotainstitute.com)
Skin microbiota act as a barrier to protect your skin from pathogens while also providing anti-inflammatory benefits. (serva-ts.com)

The number of colonies and changes in microbiota diversity were assessed in freshly collected stool samples from each tagged mouse, using traditional culture methods based on agar plates. (univ-lille.fr)

However, little is known whether evolutionary adaptation of plasmid-carrying bacteria after long-term antibiotic exposure could affect their subsequent colonization of the human gut. (amr-insights.eu)
In the present study, we explored the effect of colonization on the diversity of the gut microbiota in a DSS-induced colitis model, and determined the impact of soluble β-glucans on -host interactions. (univ-lille.fr)
This simple procedure can normalize gut microbiota colonization and development in C-section born infants, which will likely contribute to reduced risk of developing chronic diseases that abnormal gut microbiota may confer," adds Dr. Otto Helve MD, specialist in pediatric infectious diseases and shared first author of the study. (helsinki.fi)

With standard care, beneficial bacteria typically take many weeks to recover from antibiotic treatment, leaving patients at risk of other infectious diseases, including Clostridium difficile . (sbbs-soc.com)
The loss of beneficial bacteria increases the risk of certain life-threatening infectious diseases and graft-versus-host disease (GVHD). (sbbs-soc.com)
The first 25 patients who lacked known beneficial bacteria were enrolled into the study and randomly assigned to the different treatment groups: 14 received auto-FMT by enema and 11 received standard-of-care. (sbbs-soc.com)
recovery of beneficial bacteria in the 11 control patients was delayed. (sbbs-soc.com)
Whether FMT from a healthy donor would be as beneficial as the patient's own fecal sample at restoring beneficial bacteria remains to be studied. (sbbs-soc.com)

The composition of gut microbiota in early stages is determined by various factors, including mode of delivery and feeding, antibiotic exposure and surrounding environment. (frontiersin.org)
Conversely, dietary changes could be more effective to induce lasting changes in the composition of gut microbiota. (springer.com)
Furthermore, Radix dichroae extract and diclazuril treatment altered the structure and composition of gut microbiota, promoting the relative abundance of Actinobacteriota, Firmicutes, Alistipes , and Bifidobacterium , while decreasing the abundance of Bacteroidota, Marinilaceae, Helicobacteraceae, and Prevotell a. (springer.com)

These findings define a central role for commensals in regulating the migration to the MLNs of CX(3)CR1(hi) mononuclear phagocytes endowed with the ability to capture luminal bacteria, thereby compartmentalizing the intestinal immune response to avoid inflammation. (nih.gov)
One feature of inflammation-associated gut microbiotas is enrichment of motile bacteria, which can facilitate microbiota encroachment into the mucosa and activate pro-inflammatory gene expression. (nature.com)
The link between elevated microbiota flagellin levels and intestinal inflammation is thought to involve flagellin's ability to activate pro-inflammatory gene expression via TLR5 and the NLRC4 inflammasome. (nature.com)
Hence, we hypothesize that boosting levels of mucosal flagellin-specific IgA might help keep flagellated bacteria in check and, consequently protect against development of chronic gut inflammation. (nature.com)
The role of gut bacteria can vary from providing digestive support, aiding nutrient absorption, synthesizing and producing vitamins, helping to maintain normal bowel function, modulating inflammation, to even playing a part in mental health conditions such as depression and anxiety. (serva-ts.com)
Some 341 individuals were included in these two studies, and they showed that a reduced functional richness in the gut microbiota led to an increase in blood triglycerides and LDL cholesterol, as well as an increase in inflammation markers and increased insulin resistance. (news-medical.net)
Now, a 4-month randomized controlled trial in people with non-alcoholic fatty liver disease (NAFLD) indicates that daily intake of resistant starch can alter gut bacteria composition and lower liver triglycerides and liver enzymes associated with liver injury and inflammation. (eurekalert.org)

Chen P, Xu T, Zhang C, Tong X, Shaukat A, He Y, Liu K, Huang S (2022) Effects of Probiotics and Gut Microbiota on Bone metabolism in chickens: a review. (springer.com)

Among dietary component, dietary fibre may play a pivotal role by virtue of its prebiotic effect on fibre-fermenting bacteria, that may increase SCFA production. (springer.com)
A new study has found gut microbiota may play a pivotal role in the progression of endometriosis in an animal model. (medicalnewstoday.com)

More specifically, we analysed evidence from observational studies and randomized nutritional intervention investigating the relationship between gut microbiota, short-chain fatty acids and glucose metabolism. (springer.com)

Objective: We aim to understand the role of the gut commensal bacteria in the protection obtained by inoculation with a suitable vaccine for diarrheal illness. (umassmed.edu)

In this review, we focus on the recent developments related to influence of diet on this "Gut-Lung axis" as well as discuss the impact of different types of diet on gut microbiota and how they influence lung immunity as well as lung diseases. (frontiersin.org)
Apart from intestinal disorders (diabetes, obesity, colon cancer, inflammatory bowel disease, etc.), changes in dietary patterns and their effects on gut microbiota are implicated in disorders of other organs like lung (asthma, COPD, etc. (frontiersin.org)
Why is the lung microbiota so important for health? (biocodexmicrobiotainstitute.com)
Human microbiota was evaluated in lung tissue samples from workers with respiratory symptoms found to have lymphocytic bronchiolitis and alveolar ductitis with B-cell follicles and emphysema, lung tissue controls, and in skin, nasal and oral samples from 302 workers from different areas of the facility. (cdc.gov)

The rbohD knockout resulted in an enrichment of specific bacteria. (nature.com)

However, the gut microbiota of piglets is a complex ecosystem showing dynamic composition and diversity, which could change with age and diet [ 8 ]. (biomedcentral.com)

While higher-order mutants in receptors that recognize microbial features and in defence hormone signalling showed substantial microbial community alterations, the absence of the plant NADPH oxidase RBOHD caused the most pronounced change in the composition of the leaf microbiota. (nature.com)

This study evaluated the relative abundance of subgingival plaque-specific bacteria in the salivary microbiota and examined a relationship between the abundance and severity of periodontal condition in patients with periodontitis. (elsevierpure.com)

Of the 66 species- level operational taxonomic units (OTUs) representing the mean relative abundance of 1% in any of the four niches, 12 OTUs corresponding to known periodontal pathogens, including Porphyromonas gingivalis, were characteristically predominant in the subgingival plaque and constituted 37.3 ± 22.9% of the microbiota. (elsevierpure.com)

Despite the role that the human gut microbiota plays in health and diseases, little is known about its composition and functional capacity during prolonged fasting when the external nutrient supply is reduced or suppressed. (nih.gov)
This is the reason some scientists are trying to take a different approach, investigating microbiota composition in brain-related diseases. (gutmicrobiotaforhealth.com)
Here, medical oncologist Marcel van den Brink, MD, PhD , answers common questions, including how your gut microbiota impacts your health, how to protect it, and the effect it has on diseases like cancer. (mskcc.org)
FMT has been successfully used in adults to normalize gut microbiota composition and cure diseases such as recurrent Clostridium difficile infections. (helsinki.fi)
In the experiment the users investigated an enzyme that may be found in some bacteria of human gut microbiota and may have a role in the development of diabetes and other diseases. (lu.se)
Because our gut bacteria have a major impact on how we feel through the interaction between the immune system, the intestinal mucosa and our diet, the composition of the gut microbiota is of great interest to research on diseases such as Alzheimer's. (lu.se)

This was demonstrated by a consortium of scientists from the Institut Pasteur, the CNRS and Inserm, who identified a correlation between the gut microbiota and the efficacy of fluoxetine, a molecule frequently used as an antidepressant. (pasteur.fr)
The scientists obtained these results by studying the microbiotas of healthy animals and animals with mood disorders. (pasteur.fr)
By studying the DNA of these 5 bacteria, the scientists discovered that they presented strong similarities with 3 enterobacterial strains (present in the intestines) recently isolated on Earth in Tanzania and the US. (biocodexmicrobiotainstitute.com)
The scientists ran sequencing on the feces to determine the makeup of each animal's hindgut microbiota. (thehorse.com)

Microbiota dynamics and function in conferred protection by vaccine against enteric bacteria. (umassmed.edu)

Diet plays an important role in determining the composition of the gut microbiota. (frontiersin.org)

Several other studies, including this one from 2021, have suggested a link between microbiota and the progression of endometriosis. (medicalnewstoday.com)

In the BMC Microbiology journal, a team from the prestigious aerospace research center explains that the presence of these bacteria could become a hazard to astronauts during long-term missions in space, or even during the first manned space flights to Mars. (biocodexmicrobiotainstitute.com)

There are numerous bacteria, archaea, and eukaryotes living in the human gut. (news-medical.net)

The role of diet in determining gut microbiota has been studied in different stages of life. (frontiersin.org)
This discovery shows the role played by the gut microbiota in normal brain function ," continues Gérard Eberl, Head of the Microenvironment and Immunity Unit (Institut Pasteur/Inserm) and joint last author of the study. (pasteur.fr)
However, it is currently unclear how the plant shapes its leaf microbiota and what role the plant immune system plays in this process. (nature.com)
In particular, animal studies support a causal role between the composition of the gut microbiota and development of obesity, insulin resistance and type 2 diabetes (T2D). (springer.com)
Recently, it was shown that genetics plays a marginal role in the definition of microbiota composition [ 8 ]. (springer.com)
An increasing body of scientific evidence points to the important role that gut bacteria plays in a human's overall health and wellbeing. (serva-ts.com)
BACKGROUND: The intestinal microbiota plays a crucial role in the maintenance of gut homeostasis. (univ-lille.fr)
However, they weren't able to determine a causal role of gut microbiota in the progression of endometriosis. (medicalnewstoday.com)
Lachnospiraceae bacteria are already known to play an important role in energy production, she said. (thehorse.com)

further demonstrates a link between diet and microbiota. (frontiersin.org)
This proof-of-concept study demonstrates that the intestinal microbiota of infants born by C-section can be postnatally restored by maternal FMT and provides further support for the natural transfer of gut microbiota from mother to infant," says Willem M. de Vos , Professor of Human Microbiomics who was a senior author on the study. (helsinki.fi)

Indeed, artificial sweeteners are not absorbed in the gastrointestinal tract, but in passing through they encounter trillions of the bacteria in the gut microbiota. (eurekalert.org)
Our gastrointestinal tract alone is home to trillions of bacteria, a population that outnumbers human cells 10 to 1 and has 350 times the genomic material. (umassmed.edu)

0.001), in addition to the abundance of subgingival plaque microbiota (r = 0.61, P = 0.02). (elsevierpure.com)
Furthermore, the abundance of Haemophilus and Staphylococcus bacteria in vaccinees was increased over that in controls. (cdc.gov)

We proposed that the intestinal immune system is instructed by the microbiota to limit responses to luminal antigens. (nih.gov)
Our results show that the NADPH oxidase RBOHD is essential for microbiota homeostasis and emphasizes the importance of the plant immune system in controlling the leaf microbiota. (nature.com)
In fact, our gut bacteria can affect everything from our metabolism to immune system, as well as our mood and behavior . (serva-ts.com)
The gut microbiota offers benefits to the human host, such as strengthening the integrity of the gut, shaping the gut epithelium, providing protection against pathogens, synthesizing vitamins, and regulating the immune system. (news-medical.net)

Urban Puerto Rican anoles, for instance, had a high frequency of a particular bacterium that is common in humans and associated with a diet high in protein and animal fats. (the-scientist.com)
The aim of this review was to summarize and discuss current knowledge on the impact of dietary fibre as modulator of the relationship between glucose metabolism and microbiota composition in humans. (springer.com)
Therefore, in this review, we summarized current evidence from observational and intervention studies performed in humans investigating the relationship between the composition of the gut microbiota, concentration of SCFA and glucose metabolism. (springer.com)
The recent availability of high-throughput, deep-sequencing techniques has made it possible to obtain more insight in the microbiota in humans, including the not yet cultivated fraction of bacteria. (cdc.gov)

These techniques have elucidated that bacteria of the human microbiota outnumber human host cells by 10-fold, and microbiota composition varies greatly between body sites and persons. (cdc.gov)

The majority of vegan and vegetarian subjects and 30% of omnivore subjects had a high adherence to the MD. We were able to stratify individuals according to both diet type and adherence to the MD on the basis of their dietary patterns and associated microbiota. (bmj.com)

Similarly, the number of different taxa composing the microbiota of captive warthogs (richness) was similar to the microbiota of SPF pigs, demonstrating the importance of the environment the animals are raised. (pigprogress.net)

In total 6 members from different taxa were exclusively present in resistant animals: bacteria from Moraxellaceae family, Pseudomonadales order and Paludibacter , Anaerolplasma , Petrimonas and Moraxella genera. (pigprogress.net)
The aim of this study was to investigate the effect of dietary thylakoids on the gut microbiota composition, mainly the taxa of lactobacilli and bifidobacteria, in rats fed either a thylakoid-enriched diet or a control diet for 10 d. (lu.se)

Against this background, several researches have been carried out to identify potential strategies to induce specific changes in the gut microbiota composition towards microbial species with high fermentative activity. (springer.com)

Anatomy17

Organisms85

Diseases18

Chemicals and Drugs34

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes60

Disciplines and Occupations7

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture9

Information Science4

Health Care18

Geographicals1

Transplantation14

Dysbiosis7

Microbiome14

Metabolites11

Fecal microbiota transplants2

Fungi6

Bacterial12

Microbes3

Anaerobic bacteria3

Pathogenic1

Oral microbiota2

Mice27

Microorganisms3

Intestinal bacteria2

Shown that the gut microbiota2

Antibiotics7

Faecal7

Impact on the microbiota2

Modulation of gut microbiota1

Metabolic11

Transplant1

Researchers12

Skin microbiota2

Changes in microbiota1

Colonization3

Beneficial bacteria5

Composition of gut3

Inflammation7

20221

Play a pivotal role2

Short-chain1

Commensal bacteria1

Lung4

Enrichment1

Diversity1

Microbial community1

Evaluated the relative abundance1

Relative abundance1

Diseases6

Scientists4

Enteric bacteria1

Determining the composition1

20211

Microbiology1

Archaea1

Role9

Demonstrates2

Gastrointestinal tract2

Abundance2

Immune system4

Humans4

Outnumber1

Dietary patterns1

Richness1

Taxa2

Induce1