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Pasteurella multocidaPasteurella InfectionsPasteurellaRhinitis, AtrophicMicrobiologyMannheimia haemolyticaHemorrhagic SepticemiaDermotoxinsBites and StingsSwine DiseasesPasteurellosis, PneumonicBacterial ToxinsTurbinatesPasteurellaceaePasteurella pneumotropicaCattle DiseasesTurkeysSwineActinobacillus pleuropneumoniaeHaemophilus somnusBordetella InfectionsPasteurellaceae InfectionsBacterial ProteinsGlycosyltransferasesBacterial VaccinesWound InfectionBordetella bronchisepticaPoultry DiseasesSerotypingCattleActinobacillusNasal CavityBordetellaAntibodies, BacterialHaemophilusTylosinGalactitolCytotoxinsBacterial CapsulesBacteria, AerobicDNA, BacterialAnti-Bacterial AgentsThiamphenicolBacterial Outer Membrane ProteinsMicrobiological TechniquesHaemophilus paragallinarumMolecular Sequence DataFelidaeBacteriological TechniquesActinobacillus InfectionsBites, HumanSheep, BighornSulfachlorpyridazineMicrobial Sensitivity TestsNasal MucosaRespiratory Tract InfectionsBovine Respiratory Disease ComplexGTP-Binding Protein alpha Subunits, Gq-G11Bacterial Typing Techniques
MannheimiaVeterinary MicrobiologyStrainsHaemolyticaInfectionFowl choleraEscherichiaEpidemiologicalIsolates obtainedCapsularPathogenHaemorrhagic septicaemiaDepartment of Microbiology2023BacteriumClinical microbiologyAntimicrobial resistancePathogensBovine2019HaemophilusPathogenicSpeciesAroAGram-negative2022PigsSwineMeningitisHydrophobicStrainInfectionsLungBacteriaLaboratoryHumansLipopolysaccharideFindingsJournalFatalSevereHostSpectrum
Mannheimia3
Veterinary Microbiology1
Strains4
  • P. multocida strains that cause fowl cholera in poultry typically belong to the serovars 1, 3, and 4. (wikipedia.org)
  • Strains that cause atrophic rhinitis in pigs are unique as they also have P. multocida toxin (PMT) residing on a bacteriophage. (wikipedia.org)
  • The use of theBacillus subtilis sacB gene as a counter-selectable marker was assessed in serogroup A and B strains ofPasteurella multocida. (monash.edu)
  • Thus, the objective of the present study was to investigate the capacity of eight P. multocida type A field strains to cause disease in healthy pigs. (biomedcentral.com)
Haemolytica3
  • The broad utility of this system was demonstrated by generating unmarked, in-frame aroA mutants of M. haemolytica, P. multocida, and H. somnus. (usda.gov)
  • Random-amplified polymorphic DNA (RAPD) typing identified a high degree of genetic homogeneity among the M. haemolytica isolates, whereas P. multocida isolates were more heterogeneous. (edu.au)
  • These results confirm the first emergence of AMR in M. haemolytica and P. multocida from BRD cases in Australia, which should be closely monitored. (edu.au)
Infection12
  • Patients with a joint replacement (perhaps notably knee replacement) in place may, in particular, be at risk of secondary infection of that joint during an episode of P multocida cellulitis/bacteraemia. (wikipedia.org)
  • Diagnosis of the bacterium in humans was traditionally based on clinical findings, and culture and serological testing, but false negatives have been a problem due to easy death of P. multocida, and serology cannot differentiate between current infection and previous exposure. (wikipedia.org)
  • We report a case of urinary tract infection caused by an unusual genotype (sequence type 211) of Pasteurella multocida associated with human infection. (cdc.gov)
  • Pulsed-field gel electrophoresis profiles of Apa I (A) and Sma I (B) digested genomic DNA of Pasteurella multocida isolates from an 83-year-old man with a urinary tract infection (lane 1) and his pet. (cdc.gov)
  • Swine pneumonia commonly known as swine pasteurellosis is an infectious disease of swine caused by Pasteurella multocida infection. (hindawi.com)
  • Swine pneumonia, commonly known as swine pasteurellosis, is a contagious disease induced by Pasteurella multocida infection which is divided into chronic type, acute type, and most acute type according to clinical manifestations and the course of the disease [ 1 ]. (hindawi.com)
  • P. multocida is a gram-negative rod part of the commensal oropharyngeal microbiota of many household animals, and, usually, infections by P. multocida in humans is more common in the context of an animal bite leading to a skin and soft tissue infection (SSTI). (clinmedjournals.org)
  • A detailed pet history, including exposure to pets owned by friends or strangers, should reveal the possibility of Pasteurella infection. (medscape.com)
  • However, cases of Pasteurella infection occur in the total absence of an epidemiological link. (medscape.com)
  • Heydemann J, Heydemann JS, Antony S. Acute infection of a total knee arthroplasty caused by Pasteurella multocida: a case report and a comprehensive review of the literature in the last 10 years. (medscape.com)
  • Pasteurella multocida infection, a rare cause of mycotic abdominal aortic aneurysm. (medscape.com)
  • Fukuchi T, Morisawa Y. [A case of cat-scratch-induced Pasteurella multocida infection presenting with disseminated intravascular coagulation and acute renal failure]. (medscape.com)
Fowl cholera2
Escherichia2
  • Turbidimetric assessments of batch cultural growth kinetics revealed the outer membrane permeabilizer polymyxin B nonapeptide sensitized Pseudomonas aeruginosa and Escherichia coli to the hydrophobic probe novobiocin, whereas little or no sensitization was observed for two surface hydrophobicity variants of Pasteurella multocida. (okstate.edu)
  • nfsB genes, but not Pasteurella multocida nfsB, allows Escherichia coli to resist chloramphenicol by nitroreduction. (northwestern.edu)
Epidemiological1
  • 1972 ). The application of these two serotyping systems in epidemiological studies has helped to address the serotypes of P. multocida circulating in different host species and their correlations to the diseases caused by the agent, thereby contributing to the vaccine development (Singh et al. (biomedcentral.com)
Isolates obtained1
  • Molecular genetic analysis of P. multocida isolates obtained from the human patient and his pet strongly suggests a zoonotic transmission of this bacterium. (cdc.gov)
Capsular5
  • Pasteurella multocida capsular type A ( P. multocida type A) is one of the most common agents associated with bronchopneumonia in pigs [ 1 ]. (biomedcentral.com)
  • Things took an unexpected turn when isolates from our samples sent to South Africa for culture appeared to be P. multocida but failed to react with any of the four capsular types for this bacterium. (springernature.com)
  • Previously, two serotyping systems were developed based on the bacterial capsular antigens or the lipopolysaccharide (LPS) antigens which assigned P. multocida isolates into five serogroups (A, B, D, E and F) (Carter 1955 ) and/or 16 serovars (serovars 1 ~ 16), respectively (Heddleston et al. (biomedcentral.com)
  • Therefore, we undertook a separate project to determine the current profiles of capsular: LPS genotypes of P. multocida isolates in pigs of China in recent years. (biomedcentral.com)
  • To understand the capsular genotypes and LPS genotypes of swine P. multocida prevalent in pig farms of China, we investigated 158 P. multocida isolates recovered from 1371 nasal swabs and/or lungs of pigs with respiratory disorders in pig farms from 16 provinces of China between September 1, 2019 and December 12, 2020 in this study. (biomedcentral.com)
Pathogen3
  • Pasteurella multocida , a gram-negative coccobacillus, part of the normal oral flora of many domestic and wild mammals, has been described a widespread veterinary pathogen and has the potential to cause zoonotic infections in humans resulting from injuries caused by household or wild pets. (clinmedjournals.org)
  • Pasteurella multocida is a multiple host gram-negative pathogen and a leading cause of pig respiratory disorders in the world (Peng et al. (biomedcentral.com)
  • Pasteurella multocida has been added to the exclusion list for the Murine Pathogen Free™ health standard. (taconic.com)
Haemorrhagic septicaemia2
  • We performed a variety of laboratory tests and found no evidence that other bacteria, viruses, or toxins were underlying the pathology we observed, and started writing up a draft manuscript of our findings on haemorrhagic septicaemia caused by P. multocida . (springernature.com)
  • Background: Pasteurella multocida B:2 causes haemorrhagic septicaemia in cattle and buffaloes. (unair.ac.id)
Department of Microbiology1
  • Ben is studying A.baumanni in collaboration with Dr John Boyce from the Department of Microbiology and professors Roger Nation and Jian Li at the Monash Institute of Pharmaceutical Sciences. (monash.edu)
20231
Bacterium4
  • The P. multocida serotype-1 is most associated with avian cholera in North America, but the bacterium does not linger in wetlands for extended periods of time. (wikipedia.org)
  • The bacterium Pasteurella multocida is one of the most frequent commensal and opportunistic pathogens found in domestic and wild animals worldwide ( 1 ). (cdc.gov)
  • Pasteurella multocida, which is an important zoonotic pathogenic bacterium to infect a variety of livestock, such as poultry and wild animals, results in causing pasteurellosis [ 5 ]. (hindawi.com)
  • This disease, caused by the bacterium Pasteurella multocida , is seen most commonly in cattle and water buffalo. (springernature.com)
Clinical microbiology2
  • We sent a urine sample to the clinical microbiology laboratory of Hospital Universitario Central de Asturias and cultured in BBD CHROMagar Orientation Medium (Becton Dickinson, Heidelberg, Germany). (cdc.gov)
  • We placed gingival swabs obtained from the animal in Amies transport medium and sent them to the hospital's clinical microbiology laboratory, where P. multocida was recovered. (cdc.gov)
Antimicrobial resistance1
  • This study contributes to the understanding of genotypes and antimicrobial resistance profile of P. multocida currently circulation in pigs of China. (biomedcentral.com)
Pathogens2
Bovine1
  • By screening the different metabolites between high (lung)- and low (liver)-bacterial density tissues, the present work revealed that L-ascorbic acid and L-aspartic acid directly influenced bovine P. multocida growth. (figshare.com)
20192
  • Five P. multocida isolates (3.6%), all obtained from NSW in 2019, exhibited dual resistance to macrolides and tetracycline, and a further two Queensland isolates from 2019 (1.4%) exhibited a multidrug-resistant phenotype to ampicillin/penicillin, tetracycline, and tilmicosin. (edu.au)
  • To achieve this, we briefly investigated 158 P. multocida isolates from pigs with respiratory disorders in China between 2019 and 2020. (biomedcentral.com)
Haemophilus1
Pathogenic1
  • P. multocida is often found in the mouths of healthy animals but can become pathogenic under certain circumstances - like when it killed around 200,000 endangered saiga antelope in Kazakhstan in 2015. (springernature.com)
Species2
AroA1
  • Two groups of four calves each were immunized either intramuscularly (i.m. vaccinated) or intranasally (i.n. vaccinated) at 2 and 6 weeks of age with ca. 109 CFU of a derivative of P. multocida serotype B:2 strain 85020 containing a deletion in the aroA gene (strain JRMT12). (gla.ac.uk)
Gram-negative1
20221
  • A major cause of lung disease in pigs but difficult to control and eradicate[J]. Journal of Medical Microbiology ,2022,71(3):1483. (chvm.net)
Pigs4
  • Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. (biomedcentral.com)
  • According to Ross [ 6 ], the difficulty of reproducing the disease in the absence of infectious or noninfectious cofactors is a major limitation to demonstrating the primary role of P. multocida type A in pneumonic lesions in pigs. (biomedcentral.com)
  • Pasteurella multocida is a leading cause of respiratory disorders in pigs. (biomedcentral.com)
  • This study was designed to understand the genotypical and antimicrobial resistant characteristics of P. multocida from pigs in China. (biomedcentral.com)
Swine1
Meningitis2
  • Pasteurella multocida meningitis: case report and review of the last 11 y. (medscape.com)
  • Pasteurella multocida meningitis in infancy - (a lick may be as bad as a bite). (medscape.com)
Hydrophobic2
  • The LPS produced by P. multocida consists of a hydrophobic lipid A molecule (that anchors the LPS to the outer membrane), an inner core, and an outer core, both consisting of a series of sugars linked in a specific way. (wikipedia.org)
  • A hydrocarbon adherence assay revealed permeabilizing concentrations of polymyxin B nonapeptide increased cell surface hydrophobicity of P. aeruginosa and the hydrophobic P. multocida variant, while E. coli and the hydrophilic P. multocida variant remained unaffected. (okstate.edu)
Strain1
Infections2
  • In humans, P. multocida is the most common cause of wound infections after dog or cat bites. (wikipedia.org)
  • P. multocida is commonly cultured from the oropharynx of cats and dogs, and most human infections are associated with animal exposure, mainly from cats and dogs, and usually involve soft-tissue sites after animal bites or scratches ( 1 ). (cdc.gov)
Lung1
Bacteria1
  • The survival of P. multocida bacteria has also been shown to be increased by the addition of salt into their environments. (wikipedia.org)
Laboratory1
Humans1
  • See: Pasteurellosis P. multocida causes a range of diseases in wild and domesticated animals, as well as humans. (wikipedia.org)
Lipopolysaccharide2
  • P. multocida expresses a range of virulence factors including a polysaccharide capsule and the variable carbohydrate surface molecule, lipopolysaccharide (LPS). (wikipedia.org)
  • So far, limited study has been conducted to evaluate the response of endothelial cells of buffalo towards P. multocida B:2 and its lipopolysaccharide (LPS). (unair.ac.id)
Findings1
  • Findings of salivary gland fine needle aspiration (FNA) cultures provided a yield of P. multocida colonies. (clinmedjournals.org)
Journal1
Fatal1
Severe2
  • We discuss a unique case of P. multocida severe sepsis starting from a submandibular gland abscess, with no documented history of an animal bite or close contact with domestic animals. (clinmedjournals.org)
  • Conclusions: This study revealed that both whole cells P. multocida B:2 and LPS endotoxin showed similar moderate to severe cellular damage, but whole-cell P. multocida B:2 appeared to be more potent in causing much severe damage than LPS alone. (unair.ac.id)
Host2
  • P. multocida has been observed invading and replicating inside host amoebae, causing lysis in the host. (wikipedia.org)
  • This model is useful for studying the pathogenicity of other P. multocida type A isolates in the specific pig host. (biomedcentral.com)
Spectrum1