• tumour
  • Control sera were obtained from nu/nu and adult +/+ mice inoculated with tumour cells only, and from nu/nu mice protected with normal +/+ spleen cells. (springer.com)
  • In all the mice studied, CIC and blocking appeared to be mutually independent parameters throughout the MSV tumour course. (springer.com)
  • On the other hand, in immune protected mice considered alone or together with the control groups, CIC and time after tumour cell inoculation, but not tumour size, were significantly correlated. (springer.com)
  • A significant relationship between blocking and tumour size was also established, although this only applied to immune protected mice. (springer.com)
  • However, analysis of the combined data from sequentially bled immune protected mice in relation to different phases of tumour behaviour, did not support the notion that blocking, and more particularly the persistence of CIC, contribute to tumour regrowth and dissemination. (springer.com)
  • lungs
  • Most infected mice did not appear ill, and their lungs exhibited a mild and nonspecific inflammatory response. (sciencemag.org)
  • model
  • Altogether, these results show that Nude mouse appears to be a suitable small animal model to expand our insight into liver cell engraftment and regeneration. (hindawi.com)
  • We further investigated the biological consequence of Id-1 activation in tumorigenesis with the nude mouse xenograft model. (nih.gov)
  • grown
  • Brunner N, Spang-Thomsen M, Vindelov L, Wolff J, Engelholm SA (1985) Effect of tamoxifen on the receptor-positive T61 and the receptor-negative T60 human breast carcinomas grown in nude mice. (springer.com)
  • monoclonal
  • Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion that is distributed under the trade name Erbitux in the U.S. and Canada by the drug company Bristol-Myers Squibb and outside the U.S. and Canada by the drug company Merck KGaA. (wikipedia.org)
  • Cetuximab is a chimeric (mouse/human) monoclonal antibody which binds to and inhibits EGFR. (wikipedia.org)
  • human
  • Busuttil A, O'Conor GT, Foster ME, Gurtsevitch V, Morten JE, Steel CM (1986) The gross pathology and histological features of tumours produced by inoculation of human cell lines into immune-deprived mice. (springer.com)
  • Aldehyde dehydrogenase activity in xenografted human brain tumor in nude mice. (springer.com)
  • ALDH activity measured fluorimetrically using a high concentration of aliphatic aldehyde as substrate was studied in human glioblastomas grafted in nude mice. (springer.com)
  • infections
  • Taking this into consideration, Doherty and Zinkernagel were working on the response of mice to virus infections. (wikipedia.org)
  • liver
  • We aimed at reviewing the various uses of Nude mouse for the development of liver deficiency models and evaluation of efficacy of hepatic cell xenotransplantation. (hindawi.com)
  • The first part records the large range of liver deficiency models that can be developed in Nude mice: surgical partial hepatectomy, acute toxic liver deficiency, chronic cirrhosis, and transgenic liver injury. (hindawi.com)
  • Hypoglycemia in OCL-1-bearing nude mice was considered to be caused by abnormal redistribution of glycogen, i.e. , marked accumulation of glycogen in tumor tissues and depletion of glycogen in the host liver. (aacrjournals.org)
  • cells
  • In seven separate experiments, nude (nu/nu) mice carrying established murine sarcoma virus (MSV) tumours were reconstituted with syngeneic (+/+) immune splenic T cells. (springer.com)
  • main
  • The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname. (wikipedia.org)
  • normal
  • In controlled, germ free environments and with antibiotic treatments found in many laboratories that routinely use nude mice, they can live almost as long as normal mice (18 months to two years). (wikipedia.org)
  • various
  • At various time points mice were individually bled and CIC concentration and blocking activity of each individual serum was determined. (springer.com)
  • fields
  • Today the use of nude mice in the fields of infectious disease and parasitology is steadily increasing and it remains to be seen how extensive their eventual contribution to biomedical research will be. (springer.com)
  • Study
  • This study used intragastric administration of astaxanthin to detect its role on tumor proliferation, apoptosis, microRNA (miRNA) overexpression, and microbacteria composition change by establishing androgen-independent PCa cell PC-3 xenograft nude mice. (mdpi.com)