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  • NSAIDS
  • Very bad and sometimes deadly bone marrow problems and stomach or bowel problems have happened when methotrexate injection was taken with NSAIDs like ibuprofen or naproxen. (drugs.com)
  • cancer
  • Methotrexate was made in 1947 and initially came into medical use to treat cancer, as it was less toxic than the then-current treatments. (wikipedia.org)
  • Methotrexate interferes with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. (medhelp.org)
  • Methotrexate is used to treat certain types of cancer of the breast, skin, head and neck, or lung. (medhelp.org)
  • In cancer, methotrexate works by interfering with the synthesis of DNA and RNA. (hubpages.com)
  • Methotrexate is sometimes used to treat cancer even when patients do have one of the conditions listed above. (cigna.com)
  • Not all methotrexate products are used to treat cancer. (drugs.com)
  • Patients with cancer who take methotrexate injection (subcutaneous) may be at a greater risk of getting a bad health problem called tumor lysis syndrome (TLS). (drugs.com)
  • citation needed] In 1951, Jane C. Wright demonstrated the use of methotrexate in solid tumors, showing remission in breast cancer. (wikipedia.org)
  • Several years later at the National Cancer Institute, Roy Hertz and Min Chiu Li then demonstrated complete remission in women with choriocarcinoma and chorioadenoma in 1956, discovering that methotrexate alone could cure choriocarcinoma (1958), a germ-cell malignancy that originates in trophoblastic cells of the placenta. (wikipedia.org)
  • oncology
  • Bedford Laboratories (Bedford, Ohio), a division of Ben Venue Laboratories Inc, recently added Methotrexate for Injection USP, 1 g, to its line of oncology products. (pharmacytimes.com)
  • Stomach
  • And also, I read under methotrexate that it can cause stomach ulcers, which I think I already have before even starting this med. (medhelp.org)
  • bone
  • Very bad side effects like bone marrow problems, liver problems, lung problems, infections, and skin reactions (Stevens-Johnson syndrome/toxic epidermal necrolysis) can happen with methotrexate injection (subcutaneous). (drugs.com)
  • Clinical
  • Clinical characteristics of methotrexate-associated lymphoproliferative disorders: relationship between absolute lymphocyte count recovery and spontaneous regression. (springer.com)
  • commonly
  • Methotrexate is an abortifacient and is commonly used to terminate pregnancies during the early stages, generally in combination with misoprostol. (wikipedia.org)