Methods randomized controlled trials as topic. Medical search. Frequent questions

Because of this, the findings generated by RCTs are likely to be closer to the true effect than the findings generated by other research methods. (bmj.com)
Meta-analyses of randomized controlled trials (RCTs) have been considered as the highest level of evidence in the pyramid of the evidence-based medicine. (biomedcentral.com)
On a clinical research level and for pertinent research questions, randomized controlled trials (RCTs) undoubtedly offer the highest level of evidence compared to other study designs. (biomedcentral.com)
From the studies identified in this way, we selected only observational trials, randomized control trials (RCTs), and meta-analysis. (hindawi.com)
Randomized controlled trials (RCTs) provide the best quality clinical evidence. (bvsalud.org)
This review by Lyons et al 3 examined all randomized controlled trials (RCTs) of interventions which focus on reducing physical hazards within the home. (bmj.com)
Thirteen RCTs and eight non-randomized studies were identified. (bmj.com)
There were no data from RCTs on fire-related injuries, although evidence from non-randomized studies suggested that community smokealarm give-away programmes reduce fire-related injuries. (bmj.com)

The interventions consisted of providing information, and differed only in the method of delivery: by phone, in person at the clinic, or both. (nih.gov)
The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled trial, is discussed. (bmj.com)
In this article, I will explain the hierarchy of evidence in assessing the effectiveness of interventions or treatments, and discuss the randomised controlled trial, the gold standard for evaluating the effectiveness of interventions. (bmj.com)
3 The randomised controlled trial (RCT) is considered to provide the most reliable evidence on the effectiveness of interventions because the processes used during the conduct of an RCT minimise the risk of confounding factors influencing the results. (bmj.com)
The RCT is the most scientifically rigorous method of hypothesis testing available, 5 and is regarded as the gold standard trial for evaluating the effectiveness of interventions. (bmj.com)
Randomized placebo-controlled clinical trials are needed to demonstrate the potential long-term effects of pharmacological interventions. (thieme-connect.com)
2 It is therefore unsurprising that the home environment receives attention as a setting for interventions in prevention of injuries, and subsequently there have been a number of Cochrane Systematic Reviews published on the topic, summarized below. (bmj.com)
WHO urges Member States as well as international, regional and national health institutions to regularly report on AMR status to serve as an evidence base for informing strategies and devising efficient preventive and control interventions. (who.int)

An RCT's primary objective is the minimization of biases, such as selection or allocation biases, by randomizing participants into the study groups in an unbiased fashion. (biomedcentral.com)
Participants discussed hospital infection reporting laws, research on the epidemiology and prevention of healthcare-associated infections (HAIs), and current infection control practices. (cdc.gov)
So far, trials of self-management courses have not included in-depth qualitative evaluations of how the learning method influences participants' perceptions and behaviour. (kcl.ac.uk)
We aimed to interview participants who had attended a course, as part of a randomized controlled trial, to examine: (i) their perceptions of what they valued and negative aspects of the intervention, and (ii) whether and in what ways they continued to make use of the training. (kcl.ac.uk)
Methods: Twenty participants were selected within 6 months of undertaking a course from the larger randomized controlled trial conducted in England. (kcl.ac.uk)
Results: Participants' characteristics were representative of the clinical and demographic characteristics of the trial group. (kcl.ac.uk)
Participants were randomized to receive 9 months of health coaching or usual care. (annfammed.org)
RESULTS: Among 3279 case-participants and 3998 control-participants who had completed 2 mRNA doses, we estimated that the VE of a booster dose against COVID-19 declined from 86% (95% confidence interval, 81%-90%) during Delta predominance to 65% (58%-70%) during Omicron predominance. (cdc.gov)
DESIGN, SETTING, AND PARTICIPANTS: Two-group noninferiority, pragmatic, cluster-randomized trial conducted in US community hospitals, all of which used mupirocin-CHG for universal decolonization in ICUs at baseline. (cdc.gov)
The article shows that the online-courses are an effective and well-accepted approach to train professionals in topics regarding (institutional) child protection by contributing to the participants´ abilities to create medical facilities into a place of competence and protection. (biomedcentral.com)
Given increasing outpatient SBP levels in participants randomized to intensive treatment following the trial, these results highlight the importance of consistent long-term management of hypertension. (medscape.com)

Auseinandersetzung der statistischen Methode [Deliberation about the statistical method]. (jameslindlibrary.org)
Some reviews use statistical methods of meta-analysis to assess and summarize the results of multiple studies. (cdc.gov)
It's a statistical process that combines findings from individual studies, typically surrounding one topic. (bistromd.com)
Scholars@Duke publication: Statistical analysis methods for QT/QTc prolongation. (duke.edu)

We undertook a review of methodologies on causal inference methods in meta-analyses. (biomedcentral.com)

After we assessed the functional status of 439 patients with osteoarthritis, we randomly assigned them to 1 of 3 intervention groups or to a control group. (nih.gov)
We included studies that focused on young people aged 10-19 years, implemented a positive youth development intervention, were outside school hours, and utilized a randomized controlled design. (nih.gov)
The SRSD intervention teaches students the following important elements of informative essays: (a) Topic, (b) Important Details, (c) Explain Details, and (d) Ending (TIDE). (ed.gov)
Patients in the intervention group received home visit services by participant pharmacists, while the control group only received usual care. (japsonline.com)
Forty-one patients in the control group and 47 patients in the intervention group were included in the final analysis. (japsonline.com)
1990). The current paper will report results from the COMPASS pilot study, which is being conducted prior to a randomized controlled trial of intervention effectiveness. (cdc.gov)
To meet the highest evidence bar previously, researchers generally had to conduct a randomized, controlled trial, in which subjects are randomly assigned to receive an intervention or not, with other factors as closely matched as possible. (edweek.org)
In this case, the researcher sets a baseline measurement before implementing the intervention, so the subject becomes its own control group. (edweek.org)
Adult ICU patients in 137 randomized hospitals during baseline (May 1, 2015-April 30, 2017) and intervention (November 1, 2017-April 30, 2019) were included. (cdc.gov)
Randomised Controlled Trials (RCT) were conducted with one wait-list control group and one group participating in the course (= intervention group). (biomedcentral.com)
For all three courses, knowledge and practical capacities on the topic of the intervention group raised significantly in comparison to the values of the control group. (biomedcentral.com)
The authors identified 19 eligible trials, two of which investigated a home environment modification as the sole intervention with the remaining 17 using a combined approach with other strategies. (bmj.com)
This review by Kendrick et al 4 is a large review containing 80 controlled intervention studies. (bmj.com)
This review by DiGuiseppi et al 5 examined controlled studies that evaluated the effect of any intervention designed to increase the prevalence of owned or properly functioning smoke alarms on the risk of fire-related injuries, fires, and smoke alarm ownership or function. (bmj.com)

2018). Method of shoulder delivery and neonatal outcomes: A meta-analysis of prospective controlled studies. (evidencebasedbirth.com)
A systematic literature review is wildly different from a randomized controlled trial, which is still vastly different from a prospective observational study. (bistromd.com)
Investigation of the same topic in a human population by setting up a controlled, randomized, prospective trial including a sufficient amount of patients investigated according to the split-mouth method would be beneficial. (allenpress.com)
8] In a prospective, single-blind, randomized, controlled trial, 40 patients with symptomatic tibiofemoral osteoarthritis who performed 60 minutes of tai chi twice weekly for 12 weeks experienced significantly greater pain reduction than did control subjects who underwent 12 weeks of wellness education and stretching. (medscape.com)

A randomized controlled parallel-group trial was conducted in Banyumas district, Central Java province, Indonesia over 24-week period. (japsonline.com)
The Take a STAND for Health study is a 4-month, parallel-group, randomized controlled trial, in which postmenopausal patients with rheumatoid arthritis will set individually tailored, progressive goals to replace their sedentary time with standing and light-intensity activities. (edu.au)

In the second part 32 adolescents (12-13 year-old) will be cross-over randomized to these condition (i) "Moderate-Intensity Continuous Training" (MICT), (ii) "Cooperative High-Intensity Interval Training" (C-HIIT), and (iii) Sedentary condition. (biomedcentral.com)

Systematic studies on the efficacy of prevention methods for problematic pornography use are still missing, but a very important topic for future research and practice. (thieme-connect.com)
The authors of this study note that CBT (Cognitive behavioral therapy) supervision has lacked both quality control and empirical evidence to support efficacy. (ce-credit.com)
In this study, investigators at an academic medical center first developed a measurement tool within their electronic medical record to identify wrong-patient orders (and found that they were surprisingly common), then conducted a randomized trial investigating the efficacy of two different strategies to prevent wrong-patient orders. (ahrq.gov)
We performed a meta-analysis of randomized controlled trials to compare the efficacy of TP with that of IPC in patients with MPE. (tmu.edu.tw)
Building on the promising findings, we conducted a 6-week clinical trial to investigate the efficacy of BLT at midday for bipolar depression. (medscape.com)

METHODS: We evaluated the VE of a monovalent messenger RNA (mRNA) booster dose against COVID-19 from October 2021 to June 2022 among US healthcare personnel. (cdc.gov)

METHODS: MEDLINE from 1946 to present, Cochrane Database of Systematic Reviews, and Cochrane database of Registered clinical trials and EMBASE (all via OVID) were searched using the terms "laparoscopy" AND ("primary resection" OR "Hartmann procedure", OR "sigmoidectomy"), AND "Diverticulitis", AND "Peritonitis" AND "therapeutic irrigation" or "lavage" AND randomized controlled trial and any derivatives of those terms. (lu.se)

The research team will conduct two cluster randomized controlled trials. (ed.gov)

Centers for Disease Control and Prevention. (cdc.gov)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)

RESULTS: Three randomized controlled trials were identified from 48 potential studies. (lu.se)
View a selection of high-priority conditions and topics that our funded studies and projects address. (pcori.org)
The studies investigate different PD models for SRSD-an in-person, practice-based PD and an online PD-each with instructional coaching using the same method of delivery. (ed.gov)
Methods Based on theoretical considerations, empirical studies are evaluated considering the question if the main characteristics and processes involved in addictive behaviors can also be observed in problematic pornography use. (thieme-connect.com)
Systematic reviews can incorporate information from observational studies, non-randomized trials, and randomized controlled trials to clarify existing evidence about a certain topic. (cdc.gov)
Currently, systematic reviews of COVID-19 topics are being published at a very rapid pace, running the risk of synthesizing data from flawed, poorly designed studies, or studies with overlapping data. (cdc.gov)
The program integrated the use of theoretical models of causal inference from various sciences (such as psychology, economics, biostatistics) with research designs, analytic techniques and methods that support causal inferences in studies of classroom and program effects. (ed.gov)
However, studies addressing this topic remain scarce. (edu.au)
In addition to the randomized, controlled trials now considered the gold standard, education researchers are now able to use regression-discontinuity , a method that uses a cutoff point rather than random assignment to form comparison groups, and single-case studies in certain situations. (edweek.org)
In clearinghouse reviews, studies that adhere to the new standards are now considered, along with randomized, controlled trials, to result in the "strongest evidence" to guide educators and policymakers. (edweek.org)
Yet its rigorous criteria for inclusion, which focus primarily on randomized, controlled trials and quasi-experimental studies, at first found relatively few studies that met the bar. (edweek.org)
It also conducts quick reviews of the quality of individual studies on hot topics, such as charter schools. (edweek.org)
The best doctors and medical professionals in the world rely on progressive health studies to develop new and innovative treatment methods and protocols. (bistromd.com)
Researchers utilize a systematic method of locating, assembling, and evaluating a body of literature, keeping in mind certain criteria of the studies. (bistromd.com)
Using information obtained from Eli Lilly thorough QT studies, we examine the performance of several approaches to the analysis of QT changes, including subject-specific (individual) QT corrections and model-based QT analysis methods. (duke.edu)
The simulation results indicate that the mixed-effects modeling approach proposed in this paper is more powerful than the other methods, all of which are commonly used in QT studies. (duke.edu)
In October 2014, we performed a comprehensive literature search in the bibliographic database "Pubmed," looking at studies discussing the following topics: "hypovitaminosis D and physical performance: observational studies," "can vitamin D supplementation improve muscle function? (hindawi.com)
In light of IES' decision to accept some additional research methods as meeting the highest quality bar, board member Adam Gamoran said it is particularly important that the researchers "only subscribe causal inferences to studies with methodologies that allow it. (edweek.org)
Randomized controlled trials, of drowning through improvements in treatment and observational studies, case series, and review articles prevention. (bvsalud.org)
This review by Thompson et al 6 examined all controlled studies examining pool fencing with a comparison group, on the risk of drowning in children under 14 years of age. (bmj.com)
The authors found no eligible trials but three case-control studies meeting the inclusion criteria. (bmj.com)

The research design includes two cluster randomized controlled trials. (ed.gov)

METHODS Within a randomized controlled trial, we recruited English- and Spanish-speaking patients with moderate to severe COPD from urban, public primary care clinics serving a low-income, predominantly African American population. (annfammed.org)
In total, 4 trials with 500 patients were reviewed. (tmu.edu.tw)
SPRINT enrolled patients well enough to be in trials. (medscape.com)
Again, many patients we see don't have the capacity to be in a trial. (medscape.com)
In results from a recently published randomized clinical trial, [ 1 ] researchers reported significant gains in patients with bipolar depression after just 6 weeks of BLT. (medscape.com)

The results from this pilot trial provide a solid basis for further design improvements and for future research to explore appropriate techniques for widening access to social anxiety treatments in stuttering. (frontiersin.org)
For instance, to find articles covering a particular methodology, click on the Thesaurus link at the top of the page, and type in: Research Techniques to find all the different types of research methods covered in Ageline, e.g. (sfu.ca)
In Study 1, the research team will randomly assign teacher dyads to either in-person PD and coaching for SRSD instruction or a business-as-usual control group. (ed.gov)
Issues that need to be considered during the critical appraisal of randomised controlled trials, such as assessing the validity of trial methodology and the magnitude and precision of the treatment effect, and deciding on the applicability of research results, are discussed. (bmj.com)
We also talk about the latest research evidence on a very important topic- the delivery of the baby's shoulders, and how the 2-step delivery method (which has traditionally been used by midwives) can lower the risk of newborn injury at birth. (evidencebasedbirth.com)
VEST focused on three substantive research topics: (a) teacher quality, (b) early childhood, and (c) social and behavioral contexts for academic learning. (ed.gov)
Enjoyed this Research Topic? (frontiersin.org)
As part of the Institute of Education Sciences' push to make research more relevant to educators, the clearinghouse has devised standards by which it can consider two new methods for rigorous research. (edweek.org)
Abbreviated as RTC, randomized control trials are the gold standard of clinical research. (bistromd.com)
IES has set as a priority identifying new and rigorous methods to measure outcomes in education research-another nod to critics who call for the institute to broaden the scope of what it considered the highest quality research beyond randomized controlled trials. (edweek.org)
Dive into the research topics where Thomas Nilsson is active. (lu.se)

Rada (2020) described specific concerns with current methods used for systematic reviews, including restricted scope of the review, duplication of efforts and inefficiency in developing these reviews, potential for the reviews to become obsolete quickly, and poor quality (e.g., lack of rigor and transparency). (cdc.gov)

Charter schools have become hot topics for experimental design in part because the lotteries used to assign students to overenrolled schools create a natural experiment situation for researchers. (edweek.org)

When a randomized design is not feasible, data from observational study designs can be used to emulate a randomized experiment based on causal inference approach to obtain a valid causal estimate [ 3 , 4 ]. (biomedcentral.com)
ECAs are real-world patient cohorts intended to replace or enhance a control arm in clinical trials when randomization to a contemporaneous control arm is not feasible/unethical. (ispor.org)

We used generalized linear models, controlling for baseline values and clustering by site. (annfammed.org)

Key prevention methods include mandatory vaccination of personnel (unless a medical contraindication exists), consistent and appropriate infection control practices such as appropriate hand hygiene and judicious use of antimicrobial drugs, prompt detection of and responses to potential outbreaks, and routine surveillance. (cdc.gov)
Evaluation of a patient-centered fall-prevention tool kit to reduce falls and injuries: a nonrandomized controlled trial. (ahrq.gov)
Therefore, since it is a global public health problem involving several sectors, it also requires a global solution in the context of the One Health approach to achieve adequate control through the prevention, reduction, and mitigation of drug-resistant infections. (who.int)
To analyze curricular integration between teaching of patient safety and good infection prevention and control practices. (bvs.br)
Integrative review, designed to answer the question: "How does curricular integration of content about 'patient safety teaching' and content about 'infection prevention and control practices' occur in undergraduate courses in the health field? (bvs.br)
Patient safety related to infection prevention and control practices is present in the curriculum of health undergraduate courses, but is not coordinated with other themes, is taught sporadically, and focuses mainly on hand hygiene. (bvs.br)

Youth were categorized as high or low on cognitive and interpersonal risks for depression and randomized to Coping with Stress (CWS), a cognitive-behavioral program, or Interpersonal Psychotherapy - Adolescent Skills Training (IPT-AST), an interpersonal program. (chop.edu)

METHODS: MEDLINE from 1946 to present, Cochrane Database of Systematic Reviews, and Cochrane database of Registered clinical trials and EMBASE (all via OVID) were searched using the terms "laparoscopy" AND ("primary resection" OR "Hartmann. (lu.se)
The MEDLINE, and Google Scholar using a keyword search goal of these practice guidelines is to reduce the burden appropriate to each topic. (bvsalud.org)

Study 1 will compare students whose teachers participated in evidence-based PD and coaching in SRSD to a business-as-usual control group to determine whether there are effects on student writing during that year and at a 1-year follow up. (ed.gov)
Methods: This study was an examiner-blind, randomized controlled clinical trial using a split-mouth design. (tue.nl)
JAMES W. KOHLMOOS wants to see standards for many different study methods. (edweek.org)
Methods/design: The study design is a randomized controlled trial. (maastrichtuniversity.nl)
The Cogni-Action Project is divided into two stages, a cross-sectional study and a crossover-randomized trial. (biomedcentral.com)
And I need to apologize, I missed an important study in October, regarding the longer-term results of the SPRINT trial of two BP targets. (medscape.com)
Medscape: Can you briefly touch on the methods behind your study? (medscape.com)
Braces and appropriate footwear may also be of some use, although a 12-month study of 200 people aged 50 years and older with medial knee OA reported that no symptomatic or structural difference was found for those who wore lateral wedge insoles compared with flat control insoles inside their footwear. (medscape.com)

We report on findings from the first randomized controlled pilot trial of virtual reality exposure therapy (VRET) developed specifically for reducing social anxiety associated with stuttering. (frontiersin.org)

The ranking has an evolutionary order, moving from simple observational methods at the bottom, through to increasingly rigorous methodologies. (bmj.com)

Introduction Compulsive sexual behavior disorder, including problematic pornography use, has been included in the ICD-11 as impulse control disorder. (thieme-connect.com)
Results Cue-reactivity and craving in combination with reduced inhibitory control, implicit cognitions (e.g. approach tendencies) and experiencing gratification and compensation linked to pornography use have been demonstrated in individuals with symptoms of pornography-use disorder. (thieme-connect.com)
Han är en av initiativtagarna till projekt POSE, Psychotherapy Outcome and Self-selection Effects for panic disorder. (lu.se)

What are acceptable types of data and methods to build ECAs? (ispor.org)
The authors suggest that there is a need for further large or multiple smaller trials, which are sufficiently homogeneous to enable pooling of data. (bmj.com)

This program ensured the inclusion of the topic of 'patient safety' in the curriculum of health undergraduate courses ( 5 ) , but did not specify the mechanisms that should be used to evaluate the insertion of this subject. (bvs.br)

2017). Two-step shoulder delivery method reduces the incidence of shoulder dystocia. (evidencebasedbirth.com)

Methods: An integrative review was used to assess the determinants of male engagement in family planning. (scirp.org)

Offering smoke-free alternatives to adult smokers is a sensible, complementary addition to existing tobacco control strategies. (pmiscience.com)

Recently, 3 randomized controlled trials have published contradictory conclusions. (lu.se)
Conclusions: People feel socially isolated in long-term poorly controlled epilepsy. (kcl.ac.uk)
These trials try to account for as many confounding variables as possible, deeming conclusions as the most validated, reliable, and accurate. (bistromd.com)

METHODS: Eighty freshly extracted maxillary premolars were randomly divided into 4 groups (20 in each group). (who.int)

Understanding and preventing wrong-patient electronic orders: a randomized controlled trial. (ahrq.gov)

One hundred forty women with a histological diagnosis of high-grade CIN (CIN 2-3) will be randomized into two arms: imiquimod treatment during 16 weeks (experimental arm) or immediate LLETZ (standard care arm). (maastrichtuniversity.nl)
The authors concluded: "The beneficial effect of intensive treatment on cardiovascular and all-cause mortality did not persist after the trial. (medscape.com)

Under a causal inference framework, the goal is to identify and compute that effect estimate that has a causally relevant interpretation on the population the trial samples from. (biomedcentral.com)

Besides fundamental empirical models, students shall learn quasi-experimental methods of modern causal analysis. (fu-berlin.de)

Of concern is the public's emphasis on measuring HAIs versus measuring implementation of recommended infection control guidelines, given the variation of risks from institution to institution and the limitations of risk-adjustment in making reported infection rates comparable. (cdc.gov)

The mortality rate for pregnant Black women is four to five times higher than it is for white women over the age of 30, even when controlling for education. (chcs.org)

Quality of randomized controlled trials published in the International Urogynecology Journal 2007-2016. (bvsalud.org)
however, the results were sensitive to the quality of the trial. (bmj.com)

Our course in Macroeconomics is based on the Bachelor's course and provides advanced methods in modern Macroeconomic models. (fu-berlin.de)

Each practical training session is preceded by the projection of PowerPoint slides related to the theoretical topic of the session. (unimi.it)

CINAHL Complete The major nursing and allied health database for readable articles on medical topics. (sfu.ca)
The COMPASS (Community of Practice and Safety Support) team curriculum integrates health promotion and protection topics, and uses our established scripted peer-led education methods (Elliot et al. (cdc.gov)
Education and health are crucial topics for public policies as both largely determine the future wellbeing of the society. (biomedcentral.com)
Effect of restriction of the number of concurrently open records in an electronic health record on wrong-patient order errors: a randomized clinical trial. (ahrq.gov)

Diseases17

Chemicals and Drugs15

Analytical, Diagnostic and Therapeutic Techniques and Equipment87

Psychiatry and Psychology23

Phenomena and Processes14

Disciplines and Occupations13

Anthropology, Education, Sociology and Social Phenomena22

Technology, Industry, Agriculture6

Humanities7

Information Science45

Named Groups4

Health Care102

Geographicals7

RCTs8

Interventions8

Participants11

Statistical4

Meta-analyses1

Intervention14

Prospective4

Parallel-group2

Adolescents1

Efficacy5

20211

Therapeutic irrigation1

Conduct1

Centers2

Studies21

Cluster1

Patients5

Research11

20201

Researchers1

Feasible2

Baseline1

Prevention6

Cognitive1

MEDLINE2

Study8

Findings1

Rigorous1

Disorder3

Data2

Inclusion1

20171

Integrative1

Adult1

Conclusions3

Randomly1

Understanding1

Treatment2

Causal inference1

Quasi-experimental methods1

Recommended infection control1

Mortality1

Quality2

Models1

Theoretical1

Health4