Methemoglobinemia benzocaine. Medical search. Frequent questions

Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report. (pneumotox.com)
Parents should also avoid giving products with benzocaine or lidocaine , which is a local anesthetic. (newmouth.com)
There are lots of sprays, delay creams from different brands, but basically almost all of them use topical anesthetics like Lidocaine or Benzocaine . (lastsportsman.com)
Analyzing all the different sprays in the market like Stud 100, Super Dragon 6000 , Doc Johnson Power Plus Delay Cream, Viga 50000 , Deadly Delay 48000, K-Y Duration spray etc. etc., you would observe that these products are only different form each other in terms of what topical anesthetic they use, Lidocaine or Benzocaine . (lastsportsman.com)
Some reviews also claim, that lidocaine-based sprays are better than Benzocaine sprays, because unlike benzocaine, lidocaine doesn't decrease penile sensitivity substantially. (lastsportsman.com)
The thing is lidocaine absorbs Faster than benzocaine in the penile skin. (lastsportsman.com)
And this allows the makers of lidocaine based products like Promscent to use higher concentrations with more potent effects than benzocaine based sprays. (lastsportsman.com)
Since lidocaine is absorbed quickly and deeply into the penile skin, the external penis is NOT so numb as it is when benzocaine sprays are used. (lastsportsman.com)
It's clear from these posts that lidocaine can create methemoglobinemia, and the consequence of topical anesthesia just isn't drug but instead group-special. (lastsportsman.com)
Some of them are commercially available, while others do not contain lidocaine or benzocaine. (acconciaturevenus.com)

The U.S. Food and Drug Administration reported in April 2011 that use of benzocaine in products such as Anbesol , Orajel , Baby Orajel , Orabase , Hurricaine and other store-brand gels and liquids as well as sprays Cetacaine, Exactacain, and Topex can cause methemoglobinemia, a blood-related ailment that can be fatal. (klinespecter.com)
Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops. (wikipedia.org)
Benzocaine 20% (eg, Hurricaine spray, Orajel): Use caution and monitor patient for methemoglobinemia . (medscape.com)
Benzocaine gels and liquids are sold OTC under different brand names such as Anbesol, Hurricaine, Orajel, Baby Orajel, Orabase, and store brands. (gapha.org)
Benzocaine is an over-the-counter anesthetic, which the FDA notes are usually under the product names Anbesol, Hurricaine, Orajel, Baby Orajel and Orabase. (mouthhealthy.org)
Turns out, Orajel and other teething products contain a potentially dangerous drug called benzocaine, which can cause rare but deadly side effects in children, according to the Food and Drug Administation (FDA). (firstforwomen.com)
Although little Chloe was ultimately okay, her doctors still aren't sure if what happened to her was a reaction to benzocaine - the active ingredient in Orajel - or a "breath-holding spell. (firstforwomen.com)
Back in 2006, the Food and Drug Administration (FDA) released a warning about the potential dangers of products containing benzocaine - a local anesthetic used in Baby Orajel, Orajel, Orabase, Anbesol, and other topical pain relievers. (firstforwomen.com)
Benzocaine is available in a variety of formulations and can be found under several brand names, such as Anbesol, Orabase, Orajel, Baby Orajel, Hurricaine and Topex. (rxwiki.com)
In conclusion, Baby Orajel has been discontinued due to concerns over the safety of its active ingredient, benzocaine. (jaquesdalcroze.com)
Just Say No to Orajel (Benzocaine) for Teething They warned parents that benzocaine should not be used on infants and young children to soothe teething pain. (quadronmusic.com)
Is Baby Orajel without benzocaine safe? (quadronmusic.com)
Orajel™ Medicated Teething Gel (discontinued) Based on the May 23, 2018 communication from the U.S. Food and Drug Administration regarding over-the-counter (OTC) teething products containing benzocaine, we are discontinuing the distribution and sale of Orajel™ teething products containing benzocaine. (quadronmusic.com)
Just Say No to Orajel (Benzocaine) for Teething Many parents reach for Orajel or Baby Orajel, which are teething gels that contain benzocaine and are designed to soothe sore gums. (quadronmusic.com)

Lanacane - active ingredient 3% Benzocaine) Otic preparations: Solution (ex. (wikipedia.org)
Benzocaine is the active ingredient in many OTC gels, sprays, liquids and lozenges used to relieve pain in the mouth and gums from a variety of conditions such as teething, canker sores, and irritation of the mouth and gums. (boironusa.com)
Regardless of the product, the FDA recommends that consumers look at the drug label to see if benzocaine is an active ingredient. (rxwiki.com)

Symptoms of methemoglobinemia can start within just minutes to two hours after ingesting benzocaine. (drugwatch.com)
The agency was also concerned that parents with children under age 2 using these medicines at home might have trouble recognizing the signs and symptoms of methemoglobinemia. (drugwatch.com)
Symptoms of methemoglobinemia include gray or blue colored skin, lips, and nail beds and also headaches, lightheadedness, shortness of breath, fatigue and rapid heart rate. (klinespecter.com)
Symptoms of methemoglobinemia usually occur within minutes to hours of applying benzocaine, and can occur upon the first-time use or after additional use. (wikipedia.org)
In fact, the American Academy of Pediatrics doesn't recommend giving benzocaine to infants because it hasn't been shown to reliably reduce symptoms of teething. (healthline.com)
Stop using this medication and get medical help right away if you develop any symptoms of methemoglobinemia, including: pale/bluish/gray skin , unusual tiredness, shortness of breath, fast heartbeat, dizziness , headache , confusion. (webmd.com)
If you use a product that contains benzocaine, it is important to look for signs and symptoms of methemoglobinemia, the FDA warned. (rxwiki.com)
Apparently the benzocaine in these tubes was causing severe symptoms in children which were signs of methemoglobinemia (say that three times fast). (yhwhhealthfitness.com)

Some store brand-name products contain benzocaine. (drugwatch.com)
But you may want to think twice before using teething products that contain benzocaine. (rxwiki.com)
The agency is asking the manufacturers of teething products that contain benzocaine to stop marketing and selling their products for this use. (rxwiki.com)
They often contain benzocaine on the inside of the condom. (beatingprematureejaculation.org)

Throughout that time, the agency received nearly 30 reports of benzocaine gel-related cases of methemoglobinemia. (drugwatch.com)
Reported adverse event cases of methemoglobinemia associated with benzocaine products. (pneumotox.com)
The warning came after the agency received an upsetting number of benzocaine gel-related cases of methemoglobinemia - a rare but serious condition that reduces the amount of oxygen in the bloodstream - 15 of which occurred in children under two. (firstforwomen.com)

The U.S. Food and Drug Administration (FDA) is warning the public that the use of benzocaine, the main ingredient in over-the-counter (OTC) gels and liquids applied to the gums or mouth to reduce pain, is associated with a rare, but serious condition. (gapha.org)
Some dentists may recommend using teething gels containing benzocaine or choline salicylate to reduce pain. (biomedcentral.com)
Benzocaine is a common ingredient in numbing creams, ointments, and gels. (acconciaturevenus.com)
Benzocaine, a common ingredient in teething gels, can cause the rare but fatal condition blood condition called methemoglobinemia. (pediatricphysicianspc.com)
Some companies have introduced benzocaine-free teething gels or topical solutions formulated with alternative ingredients deemed safer for infants. (jaquesdalcroze.com)
The Food and Drug Administration said that various gels and creams containing the drug benzocaine can cause rare but deadly side effects in children, especially those 2 years and younger. (jaquesdalcroze.com)
In 2013, Health Canada told the companies that make teething gels with benzocaine to include label warnings about the risks of methemoglobinemia. (jaquesdalcroze.com)

The interest in benzocaine lawsuits follows the release of a new U.S. Food and Drug Administration warning about the dangers of products containing benzocaine. (drugwatch.com)

An Uncommon Complication With Use of Topical Local Anesthetic Agents: Methemoglobinemia. (pneumotox.com)
Severe methemoglobinemia from topical anesthetic spray: case report, discussion and qualitative systematic review. (pneumotox.com)
Benzodent contains benzocaine , a local anesthetic (numbing medication). (drugs.com)
The U.S. Food and Drug Administration (FDA) recently issued a warning to the public about the use of over-the-counter (OTC) products containing benzocaine, a local anesthetic. (boironusa.com)
Topical benzocaine spray is an anesthetic agent that is commonly used during transesophageal echocardiography (TEE). (elsevierpure.com)
Benzocaine has been an over-the-counter local dental anesthetic for people of all ages for many years. (newiberiasmiles.com)
Benzocaine, an anesthetic, is used to relieve pain tied to teething, as well as for other conditions. (rxwiki.com)
For local anesthetic mainly responsible benzocaine. (all-parasites.com)
This local anesthetic has been implicated in the manifestation of an insidious malady known as methemoglobinemia, wherein the body's oxygen supply is perilously curtailed. (jaquesdalcroze.com)

This is a potentially fatal condition called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a). (drugs.com)
Benzocaine has been associated with a rare but serious-and sometimes fatal-condition called methemoglobinemia, a disorder in which the amount of oxygen carried through the blood stream is greatly reduced. (mouthhealthy.org)
Benzocaine can cause a rare but serious condition called methemoglobinemia. (dukebuidds.com)
Recently, the use of benzocaine has been linked to a rare but serious condition called methemoglobinemia , a disorder that reduces the amount of oxygen being transported through the bloodstream to such low levels that it may even prove fatal. (newiberiasmiles.com)
Response to this: The concern with the products is a rare but serious condition called methemoglobinemia, which results in low oxygen levels in the blood. (jaquesdalcroze.com)
The FDA is taking action against the use of benzocaine products because they have the potential to cause a condition called methemoglobinemia. (quadronmusic.com)

Also, other chemicals that can induce methemoglobinemia have been added to the web version of Haz-Map, but have not been added to these two web pages. (haz-map.com)
Chemicals listed in Table 2 have been reported to induce methemoglobinemia in experimental animals or in humans after ingestion, intravenous administration or exposure following a chemical accident. (haz-map.com)
Olson, p. 317] Subacute methemoglobinemia, oxidative hemolysis, and Heinz body anemia may develop in susceptible individuals exposed to chemicals that can induce methemoglobinemia. (haz-map.com)
Benzocaine may induce appearance of methemoglobinemia and systemic toxicity if absorbed. (drlact.com)

This enzyme is less active in infants less than 6 months, making them more susceptible to developing methemoglobinemia than adults. (dpic.org)

Cepacol consists of menthol and benzocaine, and is used to treat sore throat. (wikipedia.org)
A solution of benzocaine and menthol is marketed for the treatment of bee stings, mosquito bites, jellyfish stings, and other insect bites Benzocaine is used as a key ingredient in numerous pharmaceuticals: Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as otitis media and swimmer's ear. (wikipedia.org)
Benzocaine And Menthol Lozenge is primarily made of two things Benzocaine, Menthol. (drlact.com)
What we have done here is we have analyzed Benzocaine for its impact on breastfeeding and analyzed Menthol for its impact on breastfeeding. (drlact.com)
Benzocaine And Menthol Lozenge is probably safe in breastfeeding however we suggest you to check detail about both below. (drlact.com)

Severe methemoglobinemia after transesophageal echocardiography. (pneumotox.com)
Severe methemoglobinemia on reexposure to benzocaine. (pneumotox.com)
Benzocaine-induced methemoglobinemia: report of a severe reaction and review of the literature. (pneumotox.com)
In the most severe cases, methemoglobinemia can result in death. (gapha.org)
in a child under 6 years old if you have difficulty in breathing, noisy breathing, or severe difficulty in swallowing if you know you are allergic to benzocaine or any of the other ingredients if you have been told you have a rare blood condition called methaemoglobinaemia if you are pregnant or breast-feeding. (tesco.com)
Sullivan, p. 376] Methemoglobinemia severe enough to require treatment is relatively rare in smoke inhalation victims. (haz-map.com)
Severe Methemoglobinemia Detected by Pulse Oximetry. (masimo.ca)
It was shown that acute administration of sodium nitrite leads to the development of methemoglobinemia, arterial and venous hypoxemia, and severe tissue hypoxia. (kiev.ua)
Benzocaine should not be applied to the breast or nipple, because the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia. (drlact.com)

The FDA has urged makers of the OTC oral anesthetics to stop marketing benzocaine products for teething in infants and young children. (drugwatch.com)
Risk of acquired methemoglobinemia with different topical anesthetics during endoscopic procedures. (pneumotox.com)
Overapplication of oral anesthetics such as benzocaine can increase the risk of pulmonary aspiration by relaxing the gag-reflex and allowing regurgitated stomach contents or oral secretions to enter the airway. (wikipedia.org)
Do not use if you have a history of allergy to local anesthetics such as procaine, butacaine, benzocaine or other "caine" anesthetics. (nih.gov)
Physicians who perform TEE and use benzocaine or other topical anesthetics need to be familiar with this potential complication and have the necessary treatment readily available. (elsevierpure.com)
Be sure to speak with your health care provider before using benzocaine and other local anesthetics. (rxwiki.com)

Hemoglobin variants associated with hemolytic anemia, altered oxygen affinity, and methemoglobinemias. (medlineplus.gov)
It is not known why some individuals have methemoglobinemia and others experience hemolytic anemia after exposure to the same oxidants. (haz-map.com)

Babies 6 months or younger are more likely to develop methemoglobinemia. (medlineplus.gov)
Young infants can develop methemoglobinemia with systemic metabolic acidosis. (cdc.gov)

Designated orphan drug by FDA for treatment of congenital methemoglobinemia. (drugs.com)

Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray. (pneumotox.com)
Methemoglobinemia with the use of benzocaine spray for awake fiberoptic intubation. (pneumotox.com)
Intraoperative detection of methemoglobinemia in a patient given benzocaine spray to relieve discomfort from a nasogastric tube: a case report. (pneumotox.com)
Benzocaine is also sold in other forms such as lozenges and spray solutions (also see separate Drug Safety Communication on Benzocaine Sprays1). (gapha.org)
0.71% w/v oromucosal spray benzocaine Ultra Chloraseptic contains a fast-acting anaesthetic called benzocaine. (tesco.com)
In rare instances, Heinz body anemia, methemoglobinemia, and hemoglobinuria may occur a few hours to 24 hours after exposure (ASPCA Animal Poison Control Center Antox: Unpublished data, 2011).5 In these cases, the thiols in the skunk spray cause oxidative damage to hemoglobin. (dvm360.com)
Although there are no reports of a cat developing methemoglobinemia from skunk spray, feline red blood cells are more sensitive to oxidative damage than are the red blood cells of other species. (dvm360.com)
And unlike the issues I have had using some benzocaine lotions, the spray causes it to be a little better to get the correct quantity. (lastsportsman.com)

Parents use benzocaine products on the gums of teething infants . (drugwatch.com)
Serious and potentially deadly side effects have been linked to the numbing agent benzocaine used by dentists and also sold over the counter to relieve oral pain such as baby teething and canker sores. (klinespecter.com)
Hundreds of cases have been reported with most occurring in children two years old or younger whose parents administered benzocaine gel for teething, according to an April 2011 warning issued by the U.S. Food and Drug Administration (FDA). (klinespecter.com)
We urge parents, caregivers, and retailers who sell them to heed our warnings and not use over-the-counter products containing benzocaine for teething pain," said FDA commissioner Scott Gottlieb, MD, in a statement . (firstforwomen.com)
But in a recent FDA warning , parents were warned to stay away from benzocaine-containing teething products. (dukebuidds.com)
Benzocaine-based teething products just don't have enough benefit to justify the risk. (dukebuidds.com)
Home » Benzocaine is Not Safe for Teething! (newiberiasmiles.com)
The FDA issued a warning in 2018 advising against the use of over-the-counter teething products containing benzocaine due to potential health risks. (jaquesdalcroze.com)
Due to the potential dangerous risk of benzocaine, we reformulated our teething products without benzocaine so that they are drug-free and ultra-safe for your baby. (quadronmusic.com)

We are also warning that benzocaine oral drug products should only be used in adults and children 2 years and older if they contain certain warnings on the drug label," the FDA said in a May 2018 statement . (mouthhealthy.org)
Recent warnings from Health Canada have highlighted the risk of methemoglobinemia with benzocaine, 1 but this rare and potentially serious adverse effect can occur with a number of other medications. (dpic.org)
In this case, the FDA is taking steps to ensure benzocaine-containing products include certain warnings on their drug labels. (rxwiki.com)
The FDA continues to add more evidence to past warnings about the risk for methemoglobinemia with the use of benzocaine products. (rxwiki.com)

According to the FDA, parents and caregivers should not use benzocaine products on children under two years of age, except under the advice and supervision of a healthcare professional. (boironusa.com)
The Food and Drug Administration recommends that parents and caregivers not use benzocaine products for children younger than 2. (mouthhealthy.org)

The FDA previously expressed concern about the use of oral benzocaine products in infants and young children because of potential serious benzocaine side effects . (drugwatch.com)
In light of these safety apprehensions, the revered U.S. Food and Drug Administration (FDA) has proffered a cautionary stance against the utilization of benzocaine-infused products in infants below the tender age of two. (jaquesdalcroze.com)

A rare side effect of transesophageal echocardiography: methemoglobinemia from topical benzocaine anesthesia. (pneumotox.com)
Benzocaine induced methemoglobinemia: a potentially fatal complication of transesophageal echocardiography. (pneumotox.com)
Toxic methemoglobinemia after topical anesthesia for transesophageal echocardiography. (elsevierpure.com)
Dive into the research topics of 'Toxic methemoglobinemia after topical anesthesia for transesophageal echocardiography. (elsevierpure.com)

Methemoglobinemia may not resolve or may rebound after initial response to therapy with methylene blue in patients with methemoglobinemia associated with aryl amines (e.g., aniline) or sulfa drugs (e.g., dapsone). (drugs.com)

With methemoglobinemia, the hemoglobin can carry oxygen, but is not able to release it effectively to body tissues. (medlineplus.gov)
This condition is called methemoglobinemia and results in the amount of oxygen carried through the blood stream being greatly reduced. (gapha.org)
Increase in the diffusion path O2 at methemoglobinemia is caused due to significant hyperhydratation of lung air-blood barrier and its individual layers, and is accompanied by a decrease in both components of the diffusion capacity of the lungs for oxygen: its membrane and blood components. (kiev.ua)
Methemoglobinemia occurs when the amount of oxygen carried through the blood is dangerously reduced. (rxwiki.com)

Gastroenteritis with vomiting and diarrhea can exacerbate nitrite formation in infants and has been reported to be a major contributor to methemoglobinemia risk in infants independent of nitrate/nitrite ingestion [Lebby et al. (cdc.gov)
Dunn Robert J. Massive sulfalazine and paracetomol ingestion causing acidosis, hyperglycemia, coagulopathy and methemoglobinemia. (kiev.ua)

Like CO, CN, and HS2 poisoning, methemoglobinemia is a form of chemical or systemic asphyxia. (haz-map.com)

It may be used for: Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, toothache, sore gums, denture irritation) Otic pain (earache) Surgical or procedural local anesthesia Relief of skin pain caused by sunburn, ingrown toenails, hemorrhoids, Examples of combination medications of benzocaine include: Antipyrine-benzocaine otic consists of antipyrine and benzocaine, and is used to relieve ear pain and remove earwax. (wikipedia.org)
Benzocaine is used short term to relieve pain from minor mouth problems (such as toothache , canker sores , sore gums/throat, mouth /gum injury). (webmd.com)

Critical rebound methemoglobinemia after methylene blue treatment: case report. (pneumotox.com)
When sodium nitrite is used for cyanide poisoning, do not use methylene blue in an attempt to treat excessive methemoglobinemia induced by the antidote because reduced cyanide binding and increased toxicity occurs. (drugs.com)

Acute myocardial infarction secondary to benzocaine induced methemoglobinemia. (kiev.ua)
Features of blood oxygenation in rats during the development of acute methemoglobinemia of low severity. (kiev.ua)

The FDA advised that benzocaine products not be used for children younger than two years old except under the advice and supervision of a health care professional. (klinespecter.com)
In the US, products containing benzocaine for oral application are contraindicated in children younger than two years old. (wikipedia.org)
The US Food and Drug Administration (FDA) is warning the public about the use of benzocaine in infants and children younger than 2 because it can pose a serious health risk. (rxwiki.com)

Methemoglobinemia can occur after one dose of the medication or after several uses, according to FDA pharmacist Mary Ghods, R.Ph. (drugwatch.com)
This condition may occur after only one use of benzocaine or after several uses. (drugs.com)

Methemoglobinemia-induced cardio-respiratory failure secondary to topical anesthesia. (pneumotox.com)
We report a case of toxic methemoglobinemia induced by benzocaine use for pharyngeal anesthesia during TEE. (elsevierpure.com)
Pulse-Oximetric Measurement of Prilocaine-Induced Methemoglobinemia in Regional Anesthesia. (masimo.ca)

Methemoglobinemia is a rare but serious and potentially fatal disorder. (drugwatch.com)
Benzocaine-related methaemoglobinemia after transoesophageal echocardiography: a rare, life-threatening complication. (pneumotox.com)
While illness from benzocaine use is very rare, infants tend to be at higher risk for complications than adults. (dukebuidds.com)
A very rare blood condition called methaemoglobinaemia has been reported with benzocaine use. (medino.com)

Benzocaine acts to inhibit the voltage-gated sodium channels (VGSCs) on the neuron membrane, stopping the propagation of the action potential. (wikipedia.org)

Allergen) Benzocaine is generally well tolerated and non-toxic when applied topically as recommended. (wikipedia.org)

Do not use large amounts of this drug or use more often than directed because the risk for serious side effects (including rarely fatal methemoglobinemia) will increase. (webmd.com)

Individuals with glucose-6-phsphate dehydrogenase (G6PD) deficiency may have greater susceptibility to the oxidizing effects of methemoglobinemia inducers. (cdc.gov)

Benzocaine mucoadhesive patches have been used in reducing orthodontic pain. (wikipedia.org)

Lawyers are accepting cases on behalf of infants, children and adults who used over-the-counter oral benzocaine products after 2007 and suffered from the life-threatening blood disorder methemoglobinemia. (drugwatch.com)
Methemoglobinemia (MetHb) is a blood disorder in which an abnormal amount of methemoglobin is produced. (medlineplus.gov)
This medication has rarely caused a very serious (possibly fatal) blood disorder (methemoglobinemia). (webmd.com)
In this initial perfusion per unit volume of tissue per time unit intrinsic for the organism defines a set of mechanisms which are responsible for changes in tissue blood flow under methemoglobinemia. (kiev.ua)

The risk or severity of methemoglobinemia can be increased when Crenolanib is combined with Ambroxol. (drugbank.com)
However, these chemical products should be used with caution due to the risk of methemoglobinemia, interference with the gag reflex, and intoxication. (biomedcentral.com)
In the case of an overdose, the risk of death or methemoglobinemia is increased. (acconciaturevenus.com)
The FDA is also warning consumers about the use of benzocaine oral products in those older than 2 because they are also at risk. (rxwiki.com)
Benzocaine products have been used for years, but in May 2018 , the FDA declared that over-the-counter (OTC) benzocaine products are a serious risk to children and infants and said that these products should be taken off the market. (jaquesdalcroze.com)

Diseases7

Chemicals and Drugs14

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Lidocaine10

Orajel14

Active ingredient3

Symptoms8

Contain benzocaine4

Cases of methemoglobinemia3

Gels7

Dangers of products containing1

Anesthetic9

Condition called methemoglobinemia6

Induce4

Susceptible to developing methem1

Menthol5

Severe9

Anesthetics6

Hemolytic anemia2

Develop methemoglobinemia2

Congenital methemoglobinemia1

Spray8

Teething9

Warnings4

Parents and caregivers2

Products in infants2

Transesophageal echocardiography4

Dapsone1

Oxygen4

Ingestion2

Systemic1

Gums2

Methylene blue2

Acute2

Children younger3

Occur2

Anesthesia3

Rare4

Sodium1

Applied topically1

Side effects1

G6PD1

Orthodontic1

Blood4

Risk5