• Moxonidine (INN) is a new-generation alpha-2/imidazoline receptor agonist antihypertensive drug licensed for the treatment of mild to moderate essential hypertension. (wikipedia.org)
  • Numerous evidences support the role of altered EET biosynthesis in the pathophysiology of hypertension and suggest the utility of antihypertensive strategies that increase CYP-derived EET or EET analogs. (frontiersin.org)
  • Some of these agents are currently under evaluation in clinical trials for treatment of hypertension and diabetes. (frontiersin.org)
  • State of Hypertension Control -- Historical Review of Combination Therapy -- Advantages of Combination Therapy Compared with Monotherapy -- Use of Combination Therapy in Special Populations -- The Evidence Base for Combination Therapy -- Combination Therapy as First-Line Treatment -- Future Combination Agents -- Clinical Inertia in the Management of Hypertension. (nshealth.ca)
  • Also for the treatment of hypertension alone or in combination with other antihypertensive agents. (medswow.com)
  • In hypertension, it is used as an adjunct to prolonged therapy with thiazides and similar agents to prevent potassium depletion. (janusinfo.se)
  • Concomitant administration of moxonidine and a thiazide diuretic such as hydrochlorothiazide gave a synergistic antihypertensive effect. (wikipedia.org)
  • In controlled clinical studies, metoprolol has been shown to be an effective antihypertensive agent when used alone or as concomitant therapy with thiazide-type diuretics, at dosages of 100 mg to 450 mg daily. (nih.gov)
  • Thiazide diuretics are commonly used in clinical practice as antihypertensive agents. (medscape.com)
  • Usually half 'Amiloride' tablet (2.5mg) given once a day together with the usual antihypertensive dosage of the thiazide concurrently employed. (janusinfo.se)
  • Inhibition of the CYP2C19 isoform may suppress the metabolism of omeprazole, subsequently altering its metabolic pathway to be metabolized by the CYP3A4 enzyme in order to maintain adequate biotransformation. (bvsalud.org)
  • Therefore, the competition for CYP3A4 may affect the metabolism of tacrolimus and result in its increased plasma concentrations, as well as in adverse reactions. (bvsalud.org)
  • Rumex acetosa L. (Polygonaceae) is well known in traditional medicine for its therapeutic efficacy as an antihypertensive. (nih.gov)
  • Did you mean topic:"antihypertensives agents - therapeutic use" ? (nshealth.ca)
  • Sestrin 2 has been studied as a therapeutic agent in obesity treatment. (bvsalud.org)
  • In this context, the obesity therapeutic property of GA can be understood from a Sestrin activating process through amino acid metabolism. (bvsalud.org)
  • Despite good clinical performance and compatibility with other therapeutic agents, Canadian HealthCare Mall recommends to consult a doctor to get qualified advice. (familyhealthcare-inc.com)
  • Metoprolol tartrate and hydrochlorothiazide tablets, USP have the antihypertensive effect of metoprolol tartrate, a selective beta 1 -adrenoreceptor blocking agent, and the antihypertensive and diuretic actions of hydrochlorothiazide. (nih.gov)
  • Potassium- conserving agent;diuretic. (janusinfo.se)
  • In congestive heart failure, Amiloride Hydrochloride may be effective alone, but its principal indication is for concomitant use in patients receiving thiazides or more potent diuretic agents. (janusinfo.se)
  • Treatment should be started with a low dose of Amiloride, i.e. 5mg (1 tablet), plus a low dosage of the other diuretic agent. (janusinfo.se)
  • A good example of this is goodrx coupon prednisone Hospet the study of the effects of the antihypertensive agent, captopril (merck), and its effects on the metabolism of cortisol and the effects on the heart and circulation, and the effects on bone metabolism. (belbal.com)
  • Peppermint oil solution administered intraluminally can be used as an antispasmodic agent with superior efficacy and fewer side effects than hyoscine-N-butylbromide. (oil-testimonials.com)
  • Zestril Per Ordine monitor blood pressure, renal Zestril Per Ordine and electrolytes in patients on Zestril and other agents that affect the RAS. (curiemag.com)
  • Cyclosporine should be administered with adrenal corticosteroids but not with other immunosuppressive agents. (wikidoc.org)
  • Kounis syndrome can be induced by various medications including antibiotics, proton pump inhibitors, antihypertensive medications, corticosteroids, and antineoplastic medications. (bvsalud.org)
  • The data indicate that l-NAME and atropine-sensitive endothelial-derived NO and COX enzyme inhibitors and Ca 2+ entry blocking-mediated vasodilator effect of the extract explain its antihypertensive potential. (nih.gov)
  • The antihypertensive effects of the drug may be enhanced in the post-sympathectomy patient. (pharmacycode.com)
  • This activity describes the indications, actions, adverse effects, and contraindications of sildenafil as an agent in the clinical setting. (nih.gov)
  • The present study examined the combined effects of an antihypertensive (S-Amlodipine) and an insulin-sensitizing agent, peroxisome proliferator-activated receptor (PPAR) agonists (Pioglitazone and Ragaglitazar), on cardiovascular risk factors in aged diabetic and insulin-resistant Zucker fa/fa rats. (biomedcentral.com)
  • Gallic acid (GA) is a triphenolic compound with beneficial biological activities including anti-inflammatory, antidiabetic, antihypertensive, and antioxidant effects. (bvsalud.org)
  • The present study considers the Phytochemicals of Desmodium adscendens and how they play important roles in the use of the herb as medicines in the treatment of various disease conditions as antimicrobial agents as well as antioxidants. (biomedgrid.com)
  • These agents block thyroid hormone synthesis. (medscape.com)
  • It is also a very potent natural antispasmodic agent. (biomedgrid.com)
  • Cyclosporine (Injection) is a immunosuppressant that is FDA approved for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants and for treatment of chronic rejection in patients previously treated with other immunosuppressive agents. (wikidoc.org)
  • The drug may also be used in the treatment of chronic rejection in patients previously treated with other immunosuppressive agents. (wikidoc.org)
  • The available drugs are not sufficiently efficacious in reducing cardiovascular risk and restoring normal glucose metabolism associated with type 2 diabetes as a mono- or a combination therapy. (biomedcentral.com)
  • In diabetic patients dosage adjustments of insulin or oral hypoglycemic agents may be required. (pharmacycode.com)
  • If necessary, dosage of both agents may be increased gradually until there is effective diuresis. (janusinfo.se)
  • A number of adverse reactions, including cerebral infarction, optic nerve infarction, angina, and ischemic changes in the electrocardiogram, have been reported with other agents when severely elevated blood pressure was reduced over time courses of several hours to as long as 1 or 2 days. (druglib.com)
  • Following abrupt cessation of therapy with certain beta-blocking agents, exacerbations of angina pectoris and in some cases, myocardial infarction have been reported. (nih.gov)
  • In hypertensive rats under similar conditions, extract and fractions showed antihypertensive effect at same doses while aqueous fraction being more potent, exhibited 68.53 ± 4.45% fall in MAP (70 mmHg). (nih.gov)
  • Ultra-short-acting agent that selectively blocks beta1-receptors with little or no effect on beta2-receptor types. (medscape.com)
  • Thiazides may cause intermittent and slight elevation of serum calcium in the absence of known disorders of calcium metabolism. (pharmacycode.com)
  • Lisinopril does not undergo metabolism and is excreted unchanged entirely in the urine. (curiemag.com)
  • Metabolism in the liver is slow and excretion is mainly in the urine, largely as unconjugated steroids. (arpimed.am)
  • The burden of the pressure targets, lifestyle interventions, antihypertensive recommendations on patients and resources, public medications, and specific management in kidney policy implications, and limitations of the evidence are transplant recipients and children. (bvsalud.org)
  • Thiourea agent that blocks production of thyroid hormones. (medscape.com)
  • The dosages and indications for these agents are not identical. (pdr.net)
  • In patients with latent cardiac insufficiency, continued depression of the myocardium with beta-blocking agents over a period of time can, in some cases, lead to cardiac failure. (druglib.com)
  • Their treatment options are limited to calcimimetic agents to reduce serum calcium levels and antiresorptive medications to protect bone health. (medscape.com)
  • These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including felodipine. (rxlist.com)
  • Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. (rxlist.com)
  • Phytoconstituents are chemical compounds produced by plants through primary or secondary metabolism, generally to help them thrive or thwart competitors, predators, or pathogens. (biomedgrid.com)
  • The study investigates antihypertensive potential of crude methanol extract (Ra.Cr) and fractions of Rumex acetosa in normotensive and hypertensive rat models and probes the underlying vascular mechanisms. (nih.gov)
  • These agents reduce iodine uptake and antibody titers of thyroid-stimulating antibodies with stabilization of the vascular bed. (medscape.com)
  • It is provided as an additional code where it is desired to identify the bacterial agent in diseases classified elsewhere. (cdc.gov)
  • The main drawback associated with β-blockers is extensive first-pass metabolism, variable bioavailability requiring frequent dose administration. (asiapharmaceutics.info)