Metabolic genetic down syndrome. Medical search. Frequent questions

Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic disorders. (cdc.gov)
These recommendations are intended for laboratories that perform biochemical genetic testing to improve the quality of laboratory services and for newborn screening laboratories to ensure the quality of laboratory practices for inherited metabolic disorders. (cdc.gov)
Figures from the National Health and Nutrition Examination Survey (NHANES) indicate that "metabolically healthy obesity" - defined as obesity without any associated metabolic disorders, such as hypertension or raised blood glucose - had more than doubled in the overall population from 1999 to 2018, but still remained a small proportion of the overall rising population with obesity. (medscape.com)
Metabolically healthy obesity" was defined as a BMI of 30 kg/m 2 or higher without any metabolic disorders, such as high blood pressure, increase in fasting plasma glucose, or changes in lipids, based on established cutoffs. (medscape.com)
neurodevelopmental, metabolic and neuromuscular disorders. (nih.gov)
Regarded as a clinicopathological clustering of metabolic disorders determining increased cardiovascular disease (CVD) risk, MetS has a polygenic inherence in which abdominal fat accumulation plays pivotal role for such epidemic morbidity [ 2 ]. (biomedcentral.com)
5480 individuals, representative of the general population aged 30 and over in Finland, were assessed for metabolic syndrome using the ATP-III criteria, gave a self-report of seasonal variations in mood and behavior, and were interviewed for mood, anxiety, and alcohol use disorders using the DSM-IV criteria. (hindawi.com)
Achondroplasia is a group of rare genetic (inherited) bone disorders. (uhhospitals.org)
The HCM associated with metabolic disorders and genetic syndromes presents early in childhood. (thieme-connect.de)
Metabolic syndrome (MetS) is defined as a panel of endocrine disorders, including central adiposity, dyslipidemia, hyperglycemia and hypertension ( Kaur, 2014 ). (frontiersin.org)
Infantile spasms can also be caused by genetic mutations or metabolic disorders. (chop.edu)
Mucopolysaccharidosis III is considered the most common of these genetic disorders, occurring with an incidence of 1 in 70,000 newborns. (medscape.com)

Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). (wikipedia.org)
The key sign of metabolic syndrome is central obesity, also known as visceral, male-pattern or apple-shaped adiposity. (wikipedia.org)
There is debate regarding whether obesity or insulin resistance is the cause of the metabolic syndrome or if they are consequences of a more far-reaching metabolic derangement. (wikipedia.org)
Central obesity is a key feature of the syndrome, as both a sign and a cause, in that the increasing adiposity often reflected in high waist circumference may both result from and contribute to insulin resistance. (wikipedia.org)
However, despite the importance of obesity, affected people who are of normal weight may also be insulin-resistant and have the syndrome. (wikipedia.org)
A series of studies described in a 2019 research article indicates a genetic association between the inflammatory and metabolic biomarkers observed in obesity and in bipolar disorder. (psychcentral.com)
You're bringing obesity onto your genetic makeup, and that can be highly variable between people. (medscape.com)
This measure is supported by the World Health Organization (WHO) as both a more accurate assessment of obesity than BMI as well as a better predictor of cardiovascular risk (WHR ≥ 0.90 cm in men and ≥ 0.85 cm in women identifies significant metabolic risk, according to the WHO), said Heymsfield, of Pennington Biomedical Research Center, Baton Rouge, Louisiana. (medscape.com)
Intrinsically related with hypertension, visceral obesity, the main component of Metabolic Syndrome (MetS), significantly contribute to the reduction of life expectancy. (biomedcentral.com)
Obesity and metabolic syndrome (O&MS) due to the worldwide obesity epidemic affects children at all stages of chronic kidney disease (CKD) including dialysis and after kidney transplantation. (springer.com)
In this CPR, we discuss the management of obesity and metabolic syndrome (O&MS) in children and adolescents with CKD stages 2-5 and on dialysis, as well as after kidney transplantation, focusing on non-pharmacological treatment (diet, physical activity and behavior modification). (springer.com)
Equine metabolic syndrome is perhaps best known for its link with the development of laminitis due to related insulin dysregulation (ID) and obesity. (thehorse.com)
The program starts with a saliva test, which identifies the user's genetic risk based on genes that affect obesity, appetite, and behavior, then after an online assessment users are assigned a coach who will help them work to reduce their weight and other risk factors. (insurancetech.com)
Metabolic syndrome is a combination of conditions that include insulin resistance/Type II diabetes, HTN, hyperlipidemia, and obesity. (nursingcenter.com)
Perhaps, the strongest risk factors for the development of NASH syndrome are obesity and insulin resistance. (nursingcenter.com)
It is often associated with obesity and diabetes and is considered a manifestation of metabolic syndrome. (tsukuba.ac.jp)
One of the causative factors that has been suggested is the parental influence in the offspring, in the sense that if either the mother or the father [or particularly both] has metabolic syndrome (a medical condition associated with obesity, high blood glucose, high cholesterol, and elevated insulin levels) then the chances of the offspring developing this disease is greater," says Dr. Kulkarni. (agemed.org)
The National Heart, Lung, and Blood Institute shares that metabolic syndrome is a group of obesity-related risk factors that increases the risk of heart disease, diabetes and stroke. (healthjockey.com)
There's for sure a genetic component to obesity. (loseit.com)
What may be helpful, says Alexander, is that you can get genetic testing for some of the genes linked to obesity, which can help doctors understand if you're predisposed to potential weight problems or even help inform the right composition of your diet. (loseit.com)
Those who have a genetic propensity to obesity need a larger calorie deficiency than you'd think they need," says Seltzer. (loseit.com)
Several studies have explored the effect of anthropometric risk ing central obesity, atherogenic dyslipidemia (ie, low high-density factors on metabolic syndrome. (cdc.gov)
However, no systematic effort has lipoprotein cholesterol [HDL-C], elevated triglycerides, and apoli- explored the effect of overweight and obesity on the prevalence of poprotein B-containing lipoproteins), elevated blood pressure, el- metabolic syndrome in India. (cdc.gov)
Hence, we under- and growing public health challenge worldwide resulting from took our meta-analysis to estimate the effect of anthropometric rapid urbanization, excessive energy intake, developing obesity, risk factors on the prevalence of metabolic syndrome to inform re- and sedentary lifestyle habits (2). (cdc.gov)
Metabolic Syndrome (MS) is the denomination proposed by the World Health Organization (WHO) 42 , which designates a set of risk factors for cardiovascular diseases (CVDs), such as visceral obesity, dyslipidemia, high hypertension, glucose intolerance and insulin resistance 32 , which frequently are presented together. (bvsalud.org)
The relatively high prevalence of the metabolic syndrome is a worldwide phenomenon that seems to be increasing in parallel with the obesity prevalence 16 . (bvsalud.org)

Insulin resistance, metabolic syndrome, and prediabetes are closely related to one another and have overlapping aspects. (wikipedia.org)
Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes. (wikipedia.org)
Rather than total adiposity, the core clinical component of the syndrome is visceral and/or ectopic fat (i.e., fat in organs not designed for fat storage) whereas the principal metabolic abnormality is insulin resistance. (wikipedia.org)
That hidden epidemic he describes is insulin resistance, sometimes called metabolic syndrome, which raises the risk of a host of diseases, from cardiovascular diseases, to various cancers and even Alzheimer's. (social-media-university-global.org)
Heterogeneity analysis revealed that an increasing index of insulin resistance was independently associated with improving the performance of adiponectin upon metabolic syndrome diagnosis (ratio of diagnostic odds ratio = 3.89, 95% CI: 1.13-13.9). (frontiersin.org)
In the Japanese population, more than 20% of the population shows insulin resistance and in the adult population with diabetes mellitus type 2 the prevalence of metabolic syndrome ranges from 38 to 53%, depending on the gender and the criterion used 16 . (bvsalud.org)

A diagnosis of metabolic syndrome requires the presence of three or more of these risk factors. (medicalnewstoday.com)
GeneReviews provides scientific information on genetic diseases, including diagnosis, treatment, and genetic counseling. (nih.gov)
Previous studies revealed the potential significance of circulating adiponectin levels with respect to the diagnosis and prediction of metabolic syndrome, but uncertainty has been noted across different cohorts. (frontiersin.org)
Genetic testing is able to identify a positive genetic diagnosis in up to 40% of children with infantile spasms syndrome. (chop.edu)
In the literature, there is a link that NAFLD is the hepatic component of the metabolic syndrome diagnosis ( Takahashi & Fukosato, 2014 ). (nursingcenter.com)
Genetic screening tests can be done to confirm a diagnosis and identify which family members have multiple endocrine neoplasia syndromes. (msdmanuals.com)
Physical examination helps in the diagnosis of specific epileptic syndromes that cause abnormal findings, such as dermatologic abnormalities (eg, patients with intractable generalized tonic-clonic seizures for years are likely to have injuries requiring stitches). (medscape.com)
Video-EEG monitoring is the standard test for classifying the type of seizure or syndrome or to diagnose pseudoseizures (ie, to establish a definitive diagnosis of spells with impairment of consciousness). (medscape.com)
Selection of an anticonvulsant medication depends on an accurate diagnosis of the epileptic syndrome. (medscape.com)

The etiology of MetS is complex, involving both environmental and genetic factors. (geneticsmr.com)
In this study, we examined the role of specific candidate genetic variants on the severity of MetS in T2D subjects. (geneticsmr.com)
A total of 13 genes and 103 single-nucleotide polymorphisms (SNPs) were analyzed to evaluate their genetic association with MetS severity in T2D subjects. (geneticsmr.com)
A consistent increase on world's Metabolic Syndrome (MetS) incidence has been associated with an epidemic cardiovascular risk in different populations. (biomedcentral.com)
The results presented demonstrate that the association between ApoE gene and CVD may be modulated by the presence of MetS, with an increased CV burden observed among E4 allele carriers with the syndrome. (biomedcentral.com)
Although a significant portion of CVD in MetS may be explained by the presence of well-known risk factors, a significant proportion remains unexplained possibly due to individual genetic variability. (biomedcentral.com)
Among those individuals with MetS, dislipidemia and its consequences (coronary artery disease, stroke and others) are attributed to a conjunct and integrative action between genetic and environmental factors. (biomedcentral.com)
ABSTRACT This study aimed to assess the prevalence, components and correlates of metabolic syndrome (MetS) in adults in pre-crisis Aleppo, Syrian Arab Republic. (who.int)
The study aimed to investigate whether the periodic Christian Orthodox fasting mitigates the changes in body composition , dietary intake , and metabolic syndrome (MetS) in postmenopausal women . (bvsalud.org)

We tested which environmental, social, lifestyle, and health related factors of the individual contribute to the seasonal variations in mood and behavior and whether these influence the risks of the metabolic syndrome and major depressive disorder, both conditions having a high prevalence in industrialized populations. (hindawi.com)
Interventions promoting physical activ- ity should be developed and implemented in phases in high-prevalence ic syndrome. (cdc.gov)

Common conditions associated with developmental delays include autism spectrum disorder, cerebral palsy, intellectual disabilities, muscular dystrophy, fetal alcohol spectrum disorder, or a rare condition such as Fragile X Syndrome. (bila.ca)

In the present study, our investigation group has shown that administration of the blue maize extract of the Mixteco race has a beneficial effect on some alterations related to MS [metabolic syndrome] as hypertension , hyperlipidemia, and abdominal fat. (medicalnewstoday.com)

The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)
The risk of GDM is determined by both genetic susceptibility and environmental factors. (biomedcentral.com)
Therefore, we intended to find GDM-associated SNPs in Chinese population and hypothesized that an early pregnancy prediction model for GDM can be constructed using genetic risk variants and clinical factors. (biomedcentral.com)
If you have bipolar disorder you may experience weight gain due to medication or other metabolic factors. (psychcentral.com)
So in the case of a person with a BMI of 30 kg/m 2 and a normal waist circumference or waist-to-hip ratio with no other metabolic risk factors, "that person is probably not obese or overfat. (medscape.com)
Metabolic syndrome is defined as a cluster of risk factors that can increase the chances of developing a number of health conditions, including heart disease , diabetes , and stroke . (medicalnewstoday.com)
Metabolic syndrome refers to this risk factor clustering for some of the more well-established and dangerous risk factors. (lu.se)
And 88% have at least one of the metabolic syndrome factors, putting them on the path toward it. (social-media-university-global.org)
To prevent equine metabolic syndrome (EMS) in aging horses-or at least severe disease associated with it- veterinarians must keep up to date on the condition and its risk factors and management tactics. (thehorse.com)
Typically, both genetic predisposition and environmental and management factors lead to the development of EMS. (thehorse.com)
Working with Neutopia, a personalized health company that uses genetic testing and behavioral science to develop "lifestyle plans," the Aetna effort aims to reduce metabolic syndrome risk factors through online food logging, activity tracking, behavior management, and one-on-one sessions with a personal coach. (insurancetech.com)
This article discusses an overview of the risk factors, cellular and genetic levels of the process, immune response, complications, and treatment of NASH. (nursingcenter.com)
As the point mutation in the tyrosinase gene is the only genetic difference between B6 albino and B6 black mice," explains Assistant Professor Hamada, "our work will facilitate the identification of genetic susceptibility factors for the development of NASH and expand the understanding of the pathophysiology of NASH. (tsukuba.ac.jp)
Genetic factors are estimated to play a role in the development of epilepsy in as many as 40% of epilepsy patients. (sciencedaily.com)
In addition the research findings indicate that other, still unknown, genetic risk factors may be present in the breed. (sciencedaily.com)
This relation was not affected by various factors such as demographics, lifestyle, sleep habits and metabolic makers. (healthjockey.com)
Risk factors include metabolic changes such as signs of the metabolic syndrome, increased inflammatory markers as well as neuroendocrine alterations. (karger.com)
There's still a lot that experts don't know about how much genetic factors influence your weight, according to Alexander, who is also the chief medical officer for Enara Health, a healthcare platform using genetic testing to optimize diet planning. (loseit.com)
Accessible Version: www.cdc.gov/pcd/issues/2022/21_0231.htm to estimate the effect of anthropometric risk factors on the preval- ence of metabolic syndrome. (cdc.gov)
Risk Factors and Metabolic Syndrome Among Adults in India: A We searched databases PubMed Central, EMBASE, MEDLINE, Systematic Review and Meta-Analysis of Observational Studies. (cdc.gov)
Metabolic syndrome recently emerged as a significant anthropometric factors and metabolic syndrome. (cdc.gov)
Introduction: Metabolic syndrome (MS) is a complex pathology that combines several risk factors for cardiovascular disease. (bvsalud.org)
The presence of at least three of these factors characterizes the syndrome. (bvsalud.org)

Board-certified internist Dr. Gillian Perkins explains how to assess your horse's body condition, what breeds are considered "easy-keepers," and how to manage and treat equine metabolic syndrome and laminitis. (cornell.edu)
Others have Equine Metabolic Syndrome (EMS), a genetic disposition to gain weight, even with appropriate feedings. (cornell.edu)
Our understanding of and recommendations about equine metabolic syndrome and PPID (pituitary pars intermedia dysfunction) certainly are continuing to progress and develop," said Katherine E. Wilson, DVM, MS, Dipl. (thehorse.com)

As the number of inherited metabolic diseases that are included in state-based newborn screening programs continues to increase, ensuring the quality of performance and delivery of testing services remains a continuous challenge not only for public health laboratories and other newborn screening facilities but also for biochemical genetic testing laboratories. (cdc.gov)
Metabolic syndrome can lead to several serious and chronic complications, including type-2 diabetes, cardiovascular diseases, stroke, kidney disease and nonalcoholic fatty liver disease. (wikipedia.org)
Major depression (MDE) has metabolic and neuroendocrine correlates, which point to a biological overlap between MDE and cardiovascular diseases. (karger.com)

Research shows that Western diet habits are a factor in development of metabolic syndrome, with high consumption of food that is not biochemically suited to humans. (wikipedia.org)
Conclusion: It is plausible that these substances may contribute to the development of metabolic syndrome. (bvsalud.org)

Concomitant metabolic or genetic syndromes can make atrial septal defect device closure difficult. (authorea.com)
found that flight evolved in tandem with concomitant genetic changes to their innate immune systems. (cdc.gov)

and presents findings from studies that have focused on psychological correlates, determinants, and consequences of the metabolic syndrome, focusing in particular on psychosocial stress and depression. (lu.se)
Video: Determinants of Alzheimer Disease -- Is Our Destiny Genetic? (psychiatrictimes.com)

First described by Wheaton 1 in 1894 and later by Apert in 1906, 2 Apert syndrome, or acrocephalosyndactyly, is an autosomal dominant malformation syndrome characterized by craniosynostosis, midface hypoplasia, syndactyly, and various visceral abnormalities. (contemporarypediatrics.com)

To evaluate the influence of genetic variants and clinical characteristics on the risk of gestational diabetes mellitus (GDM) and to construct and verify a prediction model of GDM in early pregnancy. (biomedcentral.com)
Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. (wikipedia.org)
A basic metabolic panel may be part of a routine checkup and also may be used to diagnose certain medical issues, including diabetes and kidney or lung problems. (healthline.com)
A syndrome characterized by partial pancreatic agenesis, diabetes mellitus, and heart anomalies that has_material_basis_in heterozygous mutation in GATA6 on chromosome 18q11.2. (mcw.edu)
This prior work showed significantly increased risk of both diabetes and heart disease for those living with Metabolic Syndrome," said Michael Palmer, vice president of Innovation at Aetna, in a statement. (insurancetech.com)
With this new pilot program with Newtopia, we are aiming to help members address Metabolic Syndrome through specific actions, before more serious chronic conditions arise, like diabetes and heart disease. (insurancetech.com)

Congenital abnormality of steroid metabolism (eg, adrenogenital syndrome, 17? (unboundmedicine.com)

Metabolic alkalosis usually results from severe vomiting or a potassium or chloride deficiency. (healthline.com)
Metabolic alkalosis is a condition that occurs when your blood becomes overly alkaline. (healthline.com)
Many people don't experience any symptoms of metabolic alkalosis, so you may not know that you have it. (healthline.com)
Metabolic alkalosis is one of the four main types of alkalosis . (healthline.com)
Treatment for metabolic alkalosis depends on whether your alkalosis is chloride-responsive or chloride-resistant. (healthline.com)
Metabolic alkalosis may not show any symptoms. (healthline.com)
Two organs help to compensate for metabolic alkalosis - our lungs and our kidneys. (healthline.com)
Several different underlying conditions can cause metabolic alkalosis. (healthline.com)
This is the most common cause of metabolic alkalosis. (healthline.com)

A "non-epileptic" form of GLUT1 deficiency syndrome is associated with all the typical symptoms of the condition without seizures. (nih.gov)
Infantile spasms syndrome is considered an epileptic encephalopathy, conditions in which children have both seizures and cognitive and developmental impairments. (chop.edu)
A common denominator between the different syndromes are reoccurring epileptic seizures, which are divided according to an international classification into two main groups -- focal and generalized seizures -- based on clinical symptoms and research findings. (sciencedaily.com)
This technique is also used to characterize the type of seizure and epileptic syndrome to optimize pharmacologic treatment and for presurgical workup. (medscape.com)

The current literature on the metabolic mediation of this relationship provides evidence for an association between psychological characteristics and the development of MS, which could eventually increase cardiovascular disease risk. (medscape.com)
This review shows that even though there is considerable evidence for the role of anxiety in cardiovascular problems, state-of-the-art literature does not support that metabolic alterations are a plausible physiological underlying pathway for this association. (medscape.com)
Even though the details of the causal process remain unclear, one can certainly affirm that patients presenting with psychological distress, such as anxiety, depressive symptoms and chronic stress, are in danger of metabolic alterations and of a negative cardiovascular prognosis. (medscape.com)

Study co-author Rosa Isela Guzman-Geronimoa, of the Basic Sciences Institute at the University of Veracruz in Mexico, and colleagues found that rats with diet-induced metabolic syndrome experienced a significant reduction in abdominal fat gain when fed blue corn extract. (medicalnewstoday.com)
Metabolic syndrome may include excess abdominal fat, high triglycerides, low HDL cholesterol, high blood pressure and high blood sugar. (healthjockey.com)

Identification of genetic markers has clinical relevance in this context, as for risk prediction as for adoption of therapeutic maneuvers. (biomedcentral.com)
one group had a genetic modification to have the markers of metabolic syndrome. (agemed.org)

citation needed] Recent research indicates prolonged chronic stress can contribute to metabolic syndrome by disrupting the hormonal balance of the hypothalamic-pituitary-adrenal axis (HPA-axis). (wikipedia.org)

doi:10.3201/eid1412.070641 screening showed severe metabolic in the blood cultures. (cdc.gov)
Severe neurological impairment also occurs and is usually associated with Hurler syndrome (mucopolysaccharidosis IH), Hunter syndrome (mucopolysaccharidosis II) , and Sanfilippo syndrome (mucopolysaccharidosis III). (medscape.com)

In addition, reductions in adiponectin were associated with increasing metabolic syndrome incidence in a linear dose-response manner. (frontiersin.org)
In 1997, Nelson reported an incidence of 1 case per 280,000 live births (0.36 cases per 100,000 live births) for Sanfilippo syndrome in Northern Ireland. (medscape.com)

Bipolar disorder is associated with a higher risk of metabolic syndrome . (psychcentral.com)

When Do Symptoms of Classic glucose transporter type 1 deficiency syndrome Begin? (nih.gov)

Co-occurrence of the metabolic syndrome is frequent as disturbances in metabolic networks, in glucose metabolism for instance, are implicated and often form a key component in major depressive disorder [ 16 , 17 ]. (hindawi.com)

myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and fatigue. (nih.gov)
MS is likely to develop in patients in whom genetic predisposition, chronic stress, negative emotion and unhealthy lifestyle habits converge. (medscape.com)

The research continues in the breed and aims to identify the specific mutation for genetic testing in this loci and possible in other chromosomes. (sciencedaily.com)

Glucose transporter type 1 deficiency syndrome (GLUT1 deficiency syndrome) is an inherited condition that affects the nervous system. (nih.gov)
Hartford-based health insurer Aetna is the latest to prepare a pilot from its Innovation Labs, which aims to reduce policyholders' risk for developing metabolic syndrome, a condition that affects the heart. (insurancetech.com)
Epilepsy affects about 1-5% of the human population at some stage of live, and it includes a host of syndromes the age of onset, causes and prognosis of which vary significantly. (sciencedaily.com)

Therefore, these four genetic susceptible single nucleotide polymorphisms (SNPs) and six clinical characteristics were included in the construction of the GDM early pregnancy prediction model. (biomedcentral.com)
Based on the genetic variants and clinical characteristics, this study developed and verified the early pregnancy prediction model of GDM. (biomedcentral.com)
Clinical spectrum of PRKAG2 syndrome. (thieme-connect.de)
The clinical features of Sanfilippo syndrome, including the significant CNS component (brain and spinal cord), result from the progressive lysosomal accumulation of the GAG heparan sulfate. (medscape.com)
The particular type of Sanfilippo syndrome cannot be determined based on clinical features alone. (medscape.com)

The mechanisms of the complex pathways of metabolic syndrome are under investigation. (wikipedia.org)
SFN can present in a non-length-dependent fashion and can be mistaken for syndromes such as fibromyalgia and complex regional pain syndrome. (iasp-pain.org)

There's also a condition called metabolic acidosis which occurs when your blood or fluids become overly acidic. (healthline.com)

Recently treatments have emerged for TTR amyloid neuropathy and Fabry disease, and novel biomarkers have been found both in genetic and inflammatory SFN syndromes. (iasp-pain.org)

These recommendations also are intended as a resource for medical and public health professionals who evaluate laboratory practices, for users of laboratory services to facilitate their collaboration with newborn screening systems and use of biochemical genetic tests, and for standard-setting organizations and professional societies in developing future laboratory quality standards and practice recommendations. (cdc.gov)

This disease is caused by a change in the genetic material (DNA). (nih.gov)
Objective: The aim of this study was to review the literature about the possible association between periodontal disease and metabolic syndrome and to identify the components of this syndrome that may contribute to this association. (bvsalud.org)
Can we use genetic screening of healthy populations to save lives and prevent disease? (cdc.gov)

The syndrome is thought to be caused by an underlying disorder of energy utilization and storage. (wikipedia.org)

Mutations in least 100 individual genes have been identified so far that cause infantile spasms syndrome. (chop.edu)
3 Although Apert syndrome has an autosomal dominant inheritance pattern, many cases are de novo mutations, 4 and 1 case of germinal mosaicism has been reported. (contemporarypediatrics.com)
5 The syndrome is typically caused by 2 point mutations (S252W and P253R) and 2 Alu insertions in the fibroblast growth factor receptor 2 gene (FGFR2) located on chromosome 10q26. (contemporarypediatrics.com)
Multiple endocrine neoplasia syndromes are caused by gene mutations, so they tend to run in families. (msdmanuals.com)
Multiple endocrine neoplasia syndromes are caused by genetic mutations, which are usually inherited from a parent. (msdmanuals.com)

To reach their findings , the researchers fed mice a diet high in sugar and cholesterol for 12 weeks, in order to induce metabolic syndrome. (medicalnewstoday.com)

Ongoing trials attempt to establish the efficacy of intravenous immunoglobulin in inflammatory SFN syndromes. (iasp-pain.org)

Genetic analysis supports the role of aldosterone and of MR-related pathways in the pathophysiology of depression. (karger.com)

They took a deep dive into the genetic pathways that were active in the healthy offspring versus the offspring that developed NAFLD. (agemed.org)

In the U.S., about 25% of the adult population has metabolic syndrome, a proportion increasing with age, particularly among racial and ethnic minorities. (wikipedia.org)

GLUT1 deficiency syndrome is caused by changes in the SLC2A1 gene and is inherited in an autosomal dominant manner. (nih.gov)
P, Vitale G. Israeli spotted fever Rickett- and systemic infl ammatory response by 16S rRNA gene sequencing of a sia in Sicilian Rhipicephalus sanguineus syndrome. (cdc.gov)

The seasonal variations in mood and behavior have a metabolic factor composed of weight and appetite, and greater loadings on this factor increased the risk of metabolic syndrome (odds ratio of 1.18, 95% confidence interval of 1.10 to 1.26). (hindawi.com)

Anatomy5

Diseases35

Chemicals and Drugs7

Analytical, Diagnostic and Therapeutic Techniques and Equipment14

Psychiatry and Psychology4

Phenomena and Processes14

Information Science1

Named Groups1

Health Care6

Disorders12

Obesity26

Insulin resistance6

Diagnosis9

MetS9

Prevalence2

Muscular Dystrophy1

Hypertension1

Factors23

Equine Metaboli3

Diseases3

Development of metabolic syndrome2

Concomitant2

Determinants2

Abnormalities1

Diabetes6

Congenital1

Alkalosis9

Epileptic4

Cardiovascular3

Abdominal2

Markers2

Hormonal1

Severe2

Incidence2

Bipolar disorder1

Symptoms1

Glucose metabolism1

Chronic2

Loci1

Affects3

Clinical5

Complex2

Acidosis1

Biomarkers1

Newborn Screening1

Disease3

Disorder1

Mutations5

Findings1

Inflammatory1

Pathophysiology1

Pathways1

Adult population1

Gene2

Odds ratio1