• According to the AHA, 1 in 3 US adults have three or more risk factors that contribute to CVD, metabolic disorders and/or kidney disease. (medscape.com)
  • Journal of Diabetes and Metabolic Disorders, 2018;17(6):53-61. (ejgm.org)
  • Patients with mental health disorders are particularly vulnerable to social isolation, and this has been compounded by the suspension of non-emergency care in hospitals around the world, making it difficult for patients with chronic mental illness to attend outpatient appointments. (asoi.info)
  • Endocrinologists treat diseases of the endocrine system: glandular disorders characterized by fluctuations in hormone levels. (emedicinehealth.com)
  • Metabolic disorders may also lead to MAT. (medscape.com)
  • Research in Dr. Wei's Epigenomics of Metabolic Disease Lab at Mayo Clinic is focused on epigenetic regulation of metabolic disorders and inflammatory diseases. (mayo.edu)
  • Given the significance of inflammation and steroids in a wide range of diseases, this finding may have broad implications in metabolic disorders and systemic inflammatory diseases. (mayo.edu)
  • Your health care provider may order a potassium blood test as part of your regular checkup or to monitor an existing condition, such as diabetes , kidney disease, or adrenal gland disorders . (medlineplus.gov)
  • Metabolic acidosis in CKD stimulates production of intrakidney paracrine hormones including angiotensin II, aldosterone, and endothelin-1 (ET-1) that mediate the immediate benefit of increased kidney acid excretion, but their chronic upregulation promotes inflammation and fibrosis. (nih.gov)
  • These effects, along with acid accumulation in kidney tissue, combine to accelerate progression of kidney disease. (nih.gov)
  • Obese (OB) patients are at increased risk of chronic kidney disease, but it is still unclear whether this can be attributed to obesity per se or to the associated metabolic derangements. (karger.com)
  • The aim of this study was to evaluate the relative impact of obesity and metabolic syndrome (MS) on kidney disease. (karger.com)
  • This large cross-sectional study suggests that MS and not obesity is associated with kidney damage and that the OB+ MS− phenotype does not seem to carry an increased risk of kidney disease. (karger.com)
  • Chronic kidney disease (CKD) is a common, progressive condition with a clinical spectrum ranging from mild disease to an end-stage, debilitating state [ 1 ]. (karger.com)
  • Citing the strong overlap between heart disease, kidney disease, type 2 diabetes , and obesity, the American Heart Association (AHA) has for the first time formally defined what they are calling cardiovascular-kidney-metabolic (CKM) syndrome. (medscape.com)
  • While CKM syndrome is a public health emergency, there is also great potential for improving CKM health in the population, with an increasing number of therapies that favorably impact metabolic risk factors, risk for adverse kidney events, or both, which also protect against CVD," added Ndumele, director of obesity and cardiometabolic research in the division of cardiology at Johns Hopkins University in Baltimore. (medscape.com)
  • At this stage, metabolic risk factors (hypertriglyceridemia, hypertension , metabolic syndrome , diabetes) and kidney disease are present. (medscape.com)
  • This stage describes individuals with subclinical CVD with metabolic risk factors or kidney disease or those at high predicted risk for CVD. (medscape.com)
  • Individuals with stage 4 CKM syndrome have symptomatic CVD, excess body fat, metabolic risk factors, or kidney disease. (medscape.com)
  • In patients with chronic kidney disease, metabolic syndrome has been demonstrated to be the culprit behind diverse complications. (biomedcentral.com)
  • Meanwhile, the relationship between adiponectin and metabolic syndrome in patients with chronic kidney disease has not been clarified. (biomedcentral.com)
  • The aim of this study was to elucidate the relationship between adiponectin level and metabolic syndrome in patients with chronic kidney disease. (biomedcentral.com)
  • The KoreaN Cohort Study for Outcome in Patients with Chronic Kidney Disease is a cohort study that enrolled subjects with chronic kidney disease throughout South Korea. (biomedcentral.com)
  • From February 2011 to July 2014, data were collected from 1332 patients with chronic kidney disease. (biomedcentral.com)
  • Hypoadiponectinemia is independently associated with the presence of metabolic syndrome in patients with chronic kidney disease. (biomedcentral.com)
  • Regarding the important impact on clinical outcomes of metabolic syndrome in patients with chronic kidney disease, clarification of the relationship between metabolic syndrome and adiponectin level is mandatory. (biomedcentral.com)
  • The study has a cross-sectional design, using the database system of the KoreaN Cohort Study for Outcome in Patients with Chronic Kidney Disease (KNOW-CKD), a nationwide multicenter prospective cohort including chronic kidney disease stage 1-5 pre-dialysis patients from February 2011 to July 2014. (biomedcentral.com)
  • KNOW-CKD was implemented to investigate the pathophysiologic mechanisms of renal or cardiovascular outcomes in Korean chronic kidney disease populations. (biomedcentral.com)
  • ICAMS research focuses on improving the prevention, diagnosis and treatment of clinical conditions and diseases such as heart failure, arrhythmias (irregular heartbeat), diabetes, ischaemic (coronary) heart disease, atherosclerosis, kidney disease, hypertension (high blood pressure), stroke and dementia. (gla.ac.uk)
  • Aims: we investigate whether insulin resistance is associated with an increased prevalence for chronic kidney disease irrespective of the concurrent presence of metabolic syndrome. (scirp.org)
  • The presence of chronic kidney disease (CKD) is an independent predictor of future CV events [8-11] and in the last years several studies have demonstrated that the MS increases the risk of developing microalbuminuria and renal failure [12-20]. (scirp.org)
  • The present work was directed to analyse the information of an observational Spanish study in adult population (DESIRE study) [22] in order to investigate the association of insulin resistance with the risk of chronic kidney disease (CKD) in a non diabetic population. (scirp.org)
  • These study aims were to determine the prevalence and the associated factors of chronic kidney disease among women in Indonesia. (ejgm.org)
  • Only a small percentage of 1.07 percent of respondents noticed the prevalence of chronic kidney disease. (ejgm.org)
  • The final model of a multiple logistic regression indicated that cardiovascular and cholesterol were significantly associated with the Chronic Kidney Disease (CKD) among women in Indonesia. (ejgm.org)
  • National Chronic Kidney Disease Fact Sheet. (ejgm.org)
  • Ford H. Chronic Kidney Disease (CKD). (ejgm.org)
  • Couser WG, Remuzzi G, Mendis S, Tonelli M. The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. (ejgm.org)
  • Mills KT, Xu Y, Zhang W, Bundy JD, Chen C, Kelly TN, … He J. A systematic analysis of worldwide population-based data on the global burden of chronic kidney disease in 2010. (ejgm.org)
  • Detection and prevention of chronic kidney disease in Indonesia: Initial community screening. (ejgm.org)
  • A population-based study measuring the prevalence of chronic kidney disease among adults in West Malaysia. (ejgm.org)
  • Thakkinstian A, Chaiprasert A, Hospital P, Sangthawan P, Ongaiyooth L. Prevalence and risk factors of chronic kidney disease in the Thai adult population: Thai SEEK study Prevalence and risk factors of chronic kidney disease in the Thai adult population: Thai SEEK study. (ejgm.org)
  • How Are Chronic Kidney Disease and High Potassium Related? (healthline.com)
  • Living with diabetes, heart disease, or high blood pressure can strain your kidneys and increase your risk of developing kidney disease. (healthline.com)
  • Chronic kidney disease is the gradual loss of kidney function. (healthline.com)
  • Your kidneys may not be able to process excess potassium if you have chronic kidney disease. (healthline.com)
  • Here's how to manage your potassium levels if you have or are at risk of developing chronic kidney disease. (healthline.com)
  • Chronic kidney disease increases your risk of high blood potassium levels, known as hyperkalemia. (healthline.com)
  • It's important to monitor your potassium intake if you have chronic kidney disease. (healthline.com)
  • Chronic kidney disease can reduce your kidney's ability to eliminate extra potassium in your bloodstream. (healthline.com)
  • If you have chronic kidney disease, your doctor may recommend limiting high potassium fruits and vegetables to reduce your risk of hyperkalemia. (healthline.com)
  • Occupational heat stress: one step closer to chronic kidney disease in outdoor working tasks. (cdc.gov)
  • Objective: This research aims to answer if: Heat stress in the work place, is a variable directly related to the development of chronic kidney disease? (cdc.gov)
  • Methods: For this analysis of association between exposure to occupational heat stress and development of chronic kidney disease, an exhaustive search of scientific literature was conducted, which met the subject of interest in several online databases, such as PubMed and Science Direct. (cdc.gov)
  • Conclusion: It is an immediate situation that needs attention in many other places where the weather is extremely hot and many workers are exposed to high metabolic demands, which also may ignore the risk of kidney disease to which they are exposed every day. (cdc.gov)
  • In chronic renal failure, excessive production of renin by the kidney can lead to severe high blood pressure ( hypertension ), and the effects of this may even dominate the clinical picture. (britannica.com)
  • Population Adult population in China, and specifically individuals with chronic kidney disease (about 17 million people). (bmj.com)
  • The models incorporated existing data and corresponding uncertainties from randomised trials, the China National Survey of Chronic Kidney Disease, the Global Burden of Disease Study, and the Chronic Kidney Disease Prognosis Consortium. (bmj.com)
  • In individuals with chronic kidney disease, additional deaths from cardiovascular disease related to hyperkalaemia from increased intake of potassium were calculated. (bmj.com)
  • The intervention could potentially produce an estimated 11 000 (6422 to 16 562) additional deaths related to hyperkalaemia in individuals with chronic kidney disease. (bmj.com)
  • The net effect would be about 450 000 (183 699 to 697 084) fewer deaths annually from cardiovascular disease in the overall population and 21 000 (1928 to 42 926) fewer deaths in individuals with chronic kidney disease. (bmj.com)
  • In deterministic sensitivity analyses, with changes to key model inputs and assumptions, net benefits were consistent in the total population and in individuals with chronic kidney disease, with averted deaths outweighing additional deaths. (bmj.com)
  • Taking account of the risks of hyperkalaemia, a substantial net benefit was also estimated for individuals with chronic kidney disease. (bmj.com)
  • Research objective: Epigenetic dynamics and regulatory mechanisms in kidney development and chronic kidney disease. (upenn.edu)
  • Research objective: Gene editing technology and kidney disease. (upenn.edu)
  • Research objective: Mechanistic studies of genes identified in the Genome-wide and transcriptome-wide association studies in chronic kidney disease. (upenn.edu)
  • Research objective: Exploring the mechanistic pathways of hypertension and kidney disease development to develop therapeutic targets. (upenn.edu)
  • Research objective: Single cell analysis of kidney disease. (upenn.edu)
  • Research objective: Multi-omics analysis of chronic kidney disease and diabetic kidney disease. (upenn.edu)
  • Research objective: Understanding the role for causative genes in kidney disease. (upenn.edu)
  • Elucidation of the metabolic dysfunction in chronic kidney disease. (upenn.edu)
  • Research objective: Understanding the development of chronic kidney disease, renal fibrosis, kidney repair and regeneration. (upenn.edu)
  • Research objective: Unravelling the function of genes identified in genome-wide and epigenome-wide studies in kidney disease. (upenn.edu)
  • Research objective: Understanding the role of nucleotide sensors and organelles dysfunction in chronic kidney disease development. (upenn.edu)
  • Research objective: Exploring the pathomechanism of chronic kidney disease, kidney adaptive and maladaptive repair. (upenn.edu)
  • Single cell RNA-seq analysis in kidney disease. (upenn.edu)
  • Gathering spatial transcriptomic data alongside single-cell multiomic data to better understand kidney development & disease progression. (upenn.edu)
  • Obesity and diabetes are the main causes of chronic kidney disease (CKD) and end stage renal disease (ESRD). (researchsquare.com)
  • These conditions include kidney disease , high blood pressure , and heart disease . (medlineplus.gov)
  • Kidney disease. (medlineplus.gov)
  • 1.46 mmol/L). Causes include chronic kidney disease, hypoparathyroidism, and metabolic or respiratory acidosis. (msdmanuals.com)
  • Every physician caring for patients with chronic kidney failure must determine the various factors or clinical states that may have aggravated or exacerbated the degree of kidney failure. (medscape.com)
  • In adults with chronic kidney disease, interventions to slow the progression of kidney disease that have been proven to be effective include strict blood pressure control and angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor-blocker (ARB) therapy, lipid lowering therapy, and correction of anemia. (medscape.com)
  • In addition, antihypertensive therapy is used for both renal protection and cardiovascular protection, because chronic kidney disease is associated with a marked increase in cardiovascular risk. (medscape.com)
  • According to the recommendations of the Pediatric Work Group of Kidney Disease Outcomes Quality Initiative (KDOQI) for chronic kidney disease (CKD), all children with evidence of CKD should be referred to a pediatric nephrologist for consultation and comanagement. (medscape.com)
  • Recombinant human erythropoietin (rHuEPO) has been used for chronic kidney disease (CKD)-associated anemia since 1986. (medscape.com)
  • This is targeted to maintain a transferrin saturation level of 20% or higher and serum ferritin level of 100 ng/dL or higher in children with chronic kidney disease. (medscape.com)
  • ICAMS clinicians work directly with patients in NHS hospitals within the Greater Glasgow & Clyde Health Board and in the Golden Jubilee National Hospital, which is home to Scotland's National Services in Adult Congenital Heart Disease, Advanced Heart Failure and Pulmonary Vascular Disease. (gla.ac.uk)
  • RISK Factors for the development of chronic obstructive pulmonary disease. (ac.ir)
  • Use of Plasma Biomarkers at Exacerbation of Chronic Obstructive Pulmonary Disease. (ac.ir)
  • 10. Cao C, Wang R, Wang J, Bunjhoo H, Xu Y, Xiong W. Body mass index and mortality in chronic obstructive pulmonary disease: A meta-analysis. (ac.ir)
  • 13. Rogliani P, Lucà G, Lauro D. Chronic obstructive pulmonary disease and diabetes. (ac.ir)
  • We review the fundamental relationships between the circadian timing system and biologic processes, considering how common practices, such as shift work and variations in sleep timing on work/school versus work/school-free days (ie, social jetlag), disrupt circadian alignment and predispose individuals to cardiovascular, metabolic, and pulmonary disease. (cdc.gov)
  • Oxidative stress has been implicated in the pathogenesis and progression of chronic obstructive pulmonary disease. (ersjournals.com)
  • This article reviews the presently available experimental and clinical data on the antioxidative effects of N ‐acetylcysteine in chronic obstructive pulmonary disease. (ersjournals.com)
  • Patients with chronic obstructive pulmonary disease (COPD) have decreased physical activity (PA) compared with healthy adults. (dovepress.com)
  • Chronic obstructive pulmonary disease (COPD) is a common respiratory disease, characterized by persistent symptoms and airflow limitation due to chronic inflammation often involving alveolar destruction. (dovepress.com)
  • Most deaths associated with influenza in industrialized countries are due to complications of underlying diseases in people with well defined risks, including age over 65 years, chronic cardiovascular, pulmonary, metabolic or renal disease, and immunosuppression. (who.int)
  • The metabolic syndrome (MS) describes the association, in the same subject, of several traits such as central obesity, hypertension and dyslipidaemia, all of them very common conditions in developed countries. (scirp.org)
  • Patients with pre-existing cardiovascular disease, especially hypertension and coronary heart disease, are at greatly increased risk of developing severe and fatal COVID-19 disease. (asoi.info)
  • Understanding the potential benefits of a plant-based diet for human health is crucial, particularly in the face of the rising prevalence of chronic diseases like diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer. (pucv.cl)
  • 11. Imaizumi Y, Eguchi K, Kario K. Lung Disease and Hypertension. (ac.ir)
  • Obesity is strongly associated with various diseases, such as diabetes, hypertension, cardiovascular and cerebrovascular diseases, and cancer [ 2 ]. (hindawi.com)
  • Obesity is well known for causing morbidity, mortality, disability and has been associated to an increasing number of cardiovascular and metabolic comorbidities, such as hypertension and diabetes mellitus (DM). (researchsquare.com)
  • Data from 417 patients with Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages I (29.5%), II (43.9%), III (23.5%), and IV (3.1%) were evaluated. (dovepress.com)
  • However, the resulting declines in infections in the 20th century were matched by a rise in chronic, noncommunicable diseases, for which there is no single underlying etiology. (cdc.gov)
  • ABSTRACT: The CASPIAN Study aims to implement a school-based surveillance system for prevention of noncommunicable diseases from childhood in the Islamic Republic of Iran. (who.int)
  • The prevalence of noncommunicable diseases (NCDs) is rising rapidly and they are no longer restricted to highly industrialized countries. (who.int)
  • Diabetes, like other noncommunicable diseases in the Region, receives lower attention than it deserves, despite its social, human and economic costs. (who.int)
  • In the African Region, efforts made to create an environment that enhances the fight against diabetes include adoption of resolutions AFR/RC50/R4 on noncommunicable diseases: strategy for the African Region, in 2000, and AFR/RC55/R4: cardiovascular diseases in the African Region, in 2005. (who.int)
  • The primary objective of this study was to compare weight changes in two groups of ageing Irish adults with overweight and adiposity-based chronic disease: participants who had dietary energy requirements prescribed on the base of measured RMR and participants whose RMR was estimated by a prediction equation. (thea.ie)
  • 50 years) with overweight and adiposity-based chronic disease is equal to employing a reduced-calorie diet based on the Mifflin et al. (thea.ie)
  • Indeed, nowadays psoriasis is considered a systemic pathology, including also other conditions, from psoriatic arthritis to obesity and metabolic disease (MetS), which increased cardiovascular risk in psoriatic patients [ 2 - 4 ]. (springer.com)
  • The discovery of a form of low-grade systemic and chronic inflammation ("metaflammation"), linked to inducers (broadly termed "anthropogens") associated with modern man-made environments and lifestyles, suggests an underlying basis for chronic disease that could provide a 21st-century equivalent of the germ theory. (cdc.gov)
  • Ms. Budd is an epidemiologist in the Epidemiology and Prevention Branch in the Influenza Division of CDC's National Center for Immunization and Respiratory Diseases. (cdc.gov)
  • Dr. Campbell is a Medical Officer in the Epidemiology and Prevention Branch in the Influenza Division in CDC's National Center for Immunization and Respiratory Diseases. (cdc.gov)
  • In this transition, chronic diseases and conditions (eg, heart disease, cancer, diabetes, chronic respiratory problems) - often called the "diseases of civilization" (3) - replace infections as the major source of disease. (cdc.gov)
  • Influenza virus types A and B are responsible for only a small proportion of all respiratory disease, but they are unique in their ability to cause periodic widespread outbreaks of febrile respiratory illness among adults and children. (cdc.gov)
  • Increasing hypoxemia with respiratory acidosis and advanced disease also leads to increased bronchodilator usage, thereby increasing catecholamine levels, which may contribute to development of MAT. (medscape.com)
  • RIDTs can be useful to identify influenza virus infection as a cause of respiratory outbreaks in any setting, but especially in institutions (i.e., nursing homes, chronic care facilities, and hospitals), cruise ships, summer camps, schools, etc. (cdc.gov)
  • We provide a brief overview of recent evidence for the distinct relationships between 'too much sitting' and biomarkers of metabolic health and, thus, with increased risk of type 2 diabetes, cardiovascular disease and other prevalent chronic health problems. (bmj.com)
  • Atherosclerosis, chronic non-communicable diseases, and metabolic syndrome are highly interconnected and collectively contribute to global health concerns that reduce life expectancy and quality of life. (pucv.cl)
  • While the prevalence of chronic energy deficiency among reproductive age women, malnutrition, especially stunting (height for age) among children under 5 years old, pre-clinical vitamin A deficiency and anemia among pregnant women and children remains at a high level, overweight - obesity and nutrition-related chronic non- communicable diseases (NCDs) are on the increasing trend. (who.int)
  • This study emphasizes assessing and managing metabolic syndrome in COPD patients, and suggests links between inflammation, metabolic syndrome, and impaired lung function. (ac.ir)
  • The discovery of a form of otherwise unrecognized inflammation in the early 1990s (6) and its widespread presence in many chronic diseases (7) led to the suggestion that many, if not all, such diseases may have this type of inflammatory basis (8). (cdc.gov)
  • Novel epigenetic regulators in metabolic diseases and chronic inflammation. (mayo.edu)
  • The increased risk was independent of the other common risk factors for obesity, and may reflect the effects of long-term chronic inflammation triggered by the pathogen. (holisticprimarycare.net)
  • Chronic gastrointestinal inflammation, triggered by reactions to gluten, can result in neurobehavioral symptoms which often resolve when people go gluten-free. (holisticprimarycare.net)
  • The clinical relevance of this novel diagnosis is unknown among patients with chronic hepatitis B (CHB). (uitm.edu.my)
  • COPD patients with and without metabolic syndrome: clinical and functional differences. (ac.ir)
  • The guideline definition of clinical ASCVD includes stroke, transient ischemic attack (TIA), documented coronary artery disease (CAD) with stable angina, acute coronary syndromes (ACS), coronary or other arterial revascularization, peripheral vascular disease with or without claudication, and aortic aneurysm. (acc.org)
  • The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • I'm William Koehne and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Centers for Disease Control and Prevention. (cdc.gov)
  • www.cdc.gov/pcd/issues/2022/21_0231.htm Preventing Chronic Disease. (cdc.gov)
  • Accessible Version: www.cdc.gov/pcd/issues/2022/21_0231.htm to estimate the effect of anthropometric risk factors on the preval- ence of metabolic syndrome. (cdc.gov)
  • and Cochrane library and search engines ScienceDirect and Prev Chronic Dis 2022;19:210231. (cdc.gov)
  • 2022 was a proficuous year in both the nonalcoholic fatty liver disease (NAFLD) and obesity fields. (nature.com)
  • In 2022, we witnessed advances in the field of alcohol-related liver disease. (nature.com)
  • Key studies published in 2022 highlight the emergence of several novel drugs for inflammatory bowel disease. (nature.com)
  • Metabolic dysfunction-associat. (uitm.edu.my)
  • Aims: A recent consensus document has defined metabolic dysfunction-associated fatty liver disease (MAFLD) as hepatic steatosis together with overweight, diabetes, and/or a combination of other metabolic risk factors. (uitm.edu.my)
  • Our findings highlight the importance of metabolic dysfunction in patients with CHB. (uitm.edu.my)
  • Lay summary: Recently, metabolic dysfunction-associated fatty liver disease (MAFLD) has been defined as fatty liver disease with signs of metabolic dysfunction. (uitm.edu.my)
  • A major cause of islet dysfunction is inflammatory and metabolic signaling from the islet microenvironment. (mayo.edu)
  • Cognitive dysfunction is an important complicated disease in obesity. (hindawi.com)
  • Recent studies indicated that obesity is associated with cognitive decline and neurodegenerative diseases [ 5 ].The rising epidemical evidence also shows that obesity is closely related to brain dysfunction and early onset of Alzheimer's disease [ 6 ]. (hindawi.com)
  • This review underscores the potential of a plant-based diet to target the underlying causes of these chronic diseases and enhance health outcomes for individuals and populations. (pucv.cl)
  • Primary study outcomes were measurement of daily steps (over 14 consecutive days, using an activity monitor), assessment of activity time by activity intensity (using metabolic equivalents [METs]), and evaluation of correlation between PA and patient characteristics. (dovepress.com)
  • Results from the cohort, case-control and cross-sectional studies pointed out a positive association between obesity, diabetes and risks for renal disease outcomes. (researchsquare.com)
  • Overweight and obese adults have about 5 times higher odds of having ation in the magnitude or direction of outcome, indicating the lack metabolic syndrome than adults with normal or low body weight. (cdc.gov)
  • However, no systematic effort has lipoprotein cholesterol [HDL-C], elevated triglycerides, and apoli- explored the effect of overweight and obesity on the prevalence of poprotein B-containing lipoproteins), elevated blood pressure, el- metabolic syndrome in India. (cdc.gov)
  • As population levels of overweight and obesity continue to increase, and chronic health problems from inactivity become increasingly prevalent, there is now an imperative to increase population levels of overall total daily energy expenditure. (bmj.com)
  • Retrospective analyses and single-center prospective studies identify chronic metabolic acidosis as an independent and modifiable risk factor for progression of CKD. (nih.gov)
  • In patients with CKD, untreated chronic metabolic acidosis often leads to an accelerated reduction in GFR. (nih.gov)
  • Chronic metabolic acidosis also stimulates ammoniagenesis that increases acid excretion but also leads to ammonia-induced complement activation and deposition of C3 and C5b-9 that can cause tubule-interstitial damage, further worsening disease progression. (nih.gov)
  • There's also a condition called metabolic acidosis which occurs when your blood or fluids become overly acidic. (healthline.com)
  • Population-based rates of laboratory-confirmed coronavirus disease 2019 (COVID-19)-associated hospitalizations are lacking in the United States. (cdc.gov)
  • Since SARS-CoV-2, the novel coronavirus that causes coronavirus disease 2019 (COVID-19), was first detected in December 2019 ( 1 ), approximately 1.3 million cases have been reported worldwide ( 2 ), including approximately 330,000 in the United States ( 3 ). (cdc.gov)
  • BACKGROUND: A high burden of severe disease and death from the coronavirus disease 2019 (COVID-19) has been consistently observed in older patients, especially those with pre-existing medical co-morbidities. (asoi.info)
  • In a recent study published in the Journal of American Medical Association (JAMA) Network Open , researchers found an association between male hypogonadism and hospitalization risk for coronavirus disease 2019 (COVID-19). (news-medical.net)
  • Several studies show that the presence of MS is associated to an increased risk for both cardiovascular disease [2,3] and type 2 diabetes mellitus (T2DM) [4]. (scirp.org)
  • Diabetes mellitus is a chronic disease whose global spread has given it the characteristics of a pandemic. (who.int)
  • The University of Glasgow's Institute of Cardiovascular & Medical Sciences (ICAMS) is working to tackle this global problem by exploring the causes and mechanisms of cardiovascular disease. (gla.ac.uk)
  • This comprehensive platform allows the examination of arteries at many levels that can inform us about mechanisms and causes of vascular disease and new approaches to promote vascular health. (gla.ac.uk)
  • Putative mechanisms of increased COVID-19 disease severity in diabetes include hyperglycaemia, altered immune function, sub-optimal glycaemic control during hospitalisation, a pro-thrombotic and pro-inflammatory state. (asoi.info)
  • Key studies published in 2021 demonstrated mechanisms that drive macrophage-fibroblast pathogenicity in Crohn's disease, developed multi-omics profiles to predict response to biological therapy, and suggested potential complementary treatments and new therapeutic agents in inflammatory bowel disease (IBD) therapy. (nature.com)
  • Acute or chronic pancreatitis is associated with increases in the P-type isoamylase. (medscape.com)
  • These conditions can include injuries [eg, motor vehicle trauma, occupational/sports injuries] but exclude acute diseases [eg, AIDS] that have become chronic through advances in medical treatments. (cdc.gov)
  • The condition can be short term (acute) or long term and recurrent (chronic). (medicalnewstoday.com)
  • As with acute renal failure, there are many conditions that can lead to chronic renal failure. (britannica.com)
  • Interstitial nephritis may be temporary ( acute ), or it may be long-lasting ( chronic ) and get worse over time. (stlukes-stl.com)
  • Among patients with chronic hepatitis B, MAFLD was associated with liver-related events and death. (uitm.edu.my)
  • The global pandemic lockdown has isolated many patients with chronic illnesses from their routine medical care. (asoi.info)
  • In addition, several medications affecting adiponectin level and metabolic derangements such as statins or fibrates were not considered in most previous research studies. (biomedcentral.com)
  • progression of chronic renal failure. (nih.gov)
  • The term uremia , though it is sometimes used as if it were interchangeable with chronic renal failure , really means an increase in the concentration of urea in the blood. (britannica.com)
  • These changes can lead to severe bone disease in persons suffering from renal failure, because bone calcium is depleted and the calcium stores are not adequately replenished. (britannica.com)
  • The severe symptoms are most common when the alkalosis is caused by chronic liver disease. (healthline.com)
  • She trained in pediatrics and pediatric infectious diseases including an MPH at the University of Washington. (cdc.gov)
  • The fight against infectious disease advanced dramatically with the consolidation of the germ theory in the 19th century. (cdc.gov)
  • Harris (1), Anderson (5), and others have charted the differences in thinking these changes have brought to modern epidemiology, emphasizing the difficulties in assigning causality when shifting from a mono-causal focus (promoted by the germ theory to address infectious disease) to a multi-causal focus to address chronic disease. (cdc.gov)
  • If so, and if a unifying cause could be identified to explain what is essentially a "multi-causal enterprise" (5), the implications for the management of chronic conditions could be significant, possibly reflecting the influence of the germ theory on changes in infectious disease prevention, diagnosis, treatment, and control. (cdc.gov)
  • We play an important role in discovering and developing innovative medicines and vaccines to treat and prevent infectious diseases, including HIV and Ebola. (merck.com)
  • In 1997 the World Health Organization (WHO) announced that NCD constituted a more significant contribution to ill health throughout the world than did infectious diseases. (who.int)
  • Influenza is a highly infectious disease caused by a very unstable virus. (who.int)
  • Background & Aims: COPD and metabolic syndrome are highly prevalent and contribute significantly to morbidity and mortality worldwide. (ac.ir)
  • The 2018 guideline emphasizes reducing risk of atherosclerotic cardiovascular disease (ASCVD) through lipid management. (acc.org)
  • The BHF Centre of Research Excellence, which focuses on vascular biology and biomedicine, opened in April 2014 and was awarded an initial £3M research grant to help the UK's brightest young doctors and scientists find new and innovative ways to fight cardiovascular disease and its complications. (gla.ac.uk)
  • Type 2 diabetes, which is the most common form, can be life threatening due to its complications, particularly, cardiovascular diseases. (who.int)
  • The diagram below illustrates metabolic pathways of carbohydrates. (medscape.com)
  • With GSDs, carbohydrate metabolic pathways are blocked at various levels and excess glycogen accumulates in affected tissues. (medscape.com)
  • The importance of the MS as a chronic cardiovascular risk factor and the role of insulin resistance (IR) as its principal underlying cause have been under discussion recently [7]. (scirp.org)
  • The main objective of the DESIRE study was to assess the frequency of the metabolic syndrome and insulin resistance in an adult population assigned to Primary Care centres. (scirp.org)
  • The disease presents with metabolic anomalies characterized by chronic hyperglycaemia, resulting from defective secretion or action of insulin (insulin resistance) or both. (who.int)
  • At this stage, excess weight, abdominal obesity, or dysfunctional adipose tissue (clinically manifest as impaired glucose tolerance or prediabetes) is present without other metabolic risk factors or CVD. (medscape.com)
  • Risk Factors and Metabolic Syndrome Among Adults in India: A We searched databases PubMed Central, EMBASE, MEDLINE, Systematic Review and Meta-Analysis of Observational Studies. (cdc.gov)
  • Hence, we under- and growing public health challenge worldwide resulting from took our meta-analysis to estimate the effect of anthropometric rapid urbanization, excessive energy intake, developing obesity, risk factors on the prevalence of metabolic syndrome to inform re- and sedentary lifestyle habits (2). (cdc.gov)
  • Peltzer K, Pengpid S. Prevalence, risk awareness and health beliefs of behavioural risk factors for cardiovascular disease among university students in nine ASEAN countries. (ejgm.org)
  • Weight reduction in adults aged ≥50 years over the short term (12 weeks) favoured a reduction in blood pressure, triglycerides and glucose, thus reducing cardiovascular disease risk factors. (thea.ie)
  • A reduced-energy diet based on mRMR or eRMR facilitates clinically meaningful weight reduction in adults (≥50 years) over the short term (12 weeks) and favours a reduction in blood pressure, triglycerides and glucose, thus reducing cardiovascular disease risk factors. (thea.ie)
  • Consequently, a "yellow flags" chronic orofacial pain screening for psychosocial risk factors has been proposed [ 14 ], and stress has been identified as a possible pathophysiological contributor that underlines depression and facial pain [ 15 ]. (hindawi.com)
  • Limited evidence suggests a higher prevalence of metabolic syndrome in COPD patients, indicating a potential link between metabolic syndrome and impaired lung function. (ac.ir)
  • We aimed to study the correlation between COPD severity and metabolic syndrome components, and between CRP and COPD severity. (ac.ir)
  • Immunity to these antigens, especially hemagglutinin, reduces the likelihood of infection and the severity of disease if a person does become infected. (cdc.gov)
  • These groups include young children, older adults, pregnant people, and individuals with chronic underlying medical conditions. (medicalnewstoday.com)
  • This review shows that even though there is considerable evidence for the role of anxiety in cardiovascular problems, state-of-the-art literature does not support that metabolic alterations are a plausible physiological underlying pathway for this association. (medscape.com)
  • National Center for Chronic Disease Prevention and Health Promotion. (ejgm.org)
  • Thus, this review focused on the plausible advantages of consuming a type of food pattern for the prevention and/or treatment of chronic diseases, emphasizing the dietary aspects that contribute to these conditions and the evidence supporting the benefits of a plant-based diet for human health. (pucv.cl)
  • It has the potential to revolutionise healthcare and treatment of chronic diseases such as cardiovascular disease. (gla.ac.uk)
  • Here, we critically review the literature on this topic as it pertains to the rhizosphere microbiome of crop plants and gut microbiome of pollinator insects (namely managed populations of the western honey bee, Apis mellifera), since both are frequent recipients of chronic pesticide exposure. (researchgate.net)
  • Rapid and chronic molecular responses are induced when pancreatic islets are exposed to adverse conditions. (mayo.edu)
  • Even if people meet the current recommendation of 30 minutes of physical activity on most days each week, there may be significant adverse metabolic and health effects from prolonged sitting - the activity that dominates most people's remaining "non-exercise" waking hours. (bmj.com)
  • Main outcome measures Averted deaths from cardiovascular disease, non-fatal events, and disability adjusted life years from a reduction in blood pressure were estimated after implementation of potassium enriched salt substitution. (bmj.com)
  • The cardiovascular examination should be aimed at excluding underlying structural heart diseases such as valvular abnormalities and heart failure. (medscape.com)
  • Prev Chronic Dis 2012;9:110301. (cdc.gov)
  • As with generalized obesity, the lifestyle changes to eliminate one or more of the metabolic syndrome components often need a multidisciplinary effort over long periods of time to prevent recidivism. (acc.org)
  • Diabetes is a chronic disease characterized by chronic hyperglycaemia which requires lifelong treatment. (who.int)