• Asbestos-related pulmonary complications include asbestosis, pleural plaques, diffuse pleural thickening, benign asbestos-related pleural effusions, and malignant pleural mesothelioma. (medscape.com)
  • More common diseases, such as benign asbestos-related pleural disease and metastatic adenocarcinoma, can look radiographically identical to mesothelioma. (medscape.com)
  • Diffuse pleural thickening or extensive lobular pleural-based masses are seen in about 50% of cases. (medscape.com)
  • A clinical history of asbestos exposure and radiologic findings that are consistent with mesothelioma warrant inclusion of mesothelioma in the differential diagnosis, but it is important to stress that a diagnosis of mesothelioma cannot be made exclusively with imaging studies. (medscape.com)
  • CT is the imaging modality of choice to assess pleural disease and has shown sensitivity and specificity for identifying malignancy. (medscape.com)
  • Some mesenteric diseases present with distinctive imaging findings while others have similar findings, thereby complicating their differential diagnosis. (sajr.org.za)
  • Pleural effusions are common and may obscure the presence of the underlying pleural thickening. (medscape.com)
  • However, a subgroup of patients presents a clinically aggressive course with disease progression despite receiving treatment. (rare-cancer.org)
  • Lung nodules and hilar masses usually result from direct mesothelioma tumor extension into the lung parenchyma and mediastinal structures, such as lymph nodes, the pericardium, and the heart. (medscape.com)
  • Mechanical distortion of the hemithorax, chest wall masses, periosteal rib reaction or rib destruction by the tumor are signs of advanced disease. (medscape.com)
  • The radiographic findings of mesothelioma are nonspecific and are observed in other diseases, including metastatic carcinoma, lymphoma, and benign asbestos disease. (medscape.com)
  • The diagnosis of mesothelioma should be made with care. (medscape.com)
  • Biopsy with special staining and immunohistochemical and ultrastructural analysis are absolutely essential for the accurate diagnosis of mesothelioma. (medscape.com)
  • CT plays an essential role in the diagnosis of mesenteric disease. (sajr.org.za)
  • Case studies of asbestos-related disease are illustrated in the images below. (medscape.com)
  • The most common mesothelioma finding on radiographs is unilateral, concentric, plaquelike, or nodular pleural thickening (as seen in the images below). (medscape.com)
  • Although primary neoplasms arising in the mesentery are rare, the mesentery is a major avenue for the dissemination of tumours, which can spread through hematogenous, lymphatic, direct or peritoneal seeding. (sajr.org.za)
  • Knowledge of asbestos-related diseases accumulated for over 100 years as the industrial value of asbestos became recognized for the strength of its fibers and their resistance to destruction, resulting in increasing production and use until multiple health effects became apparent. (medscape.com)
  • Evaluation of the mesentery is often neglected during routine ultrasound (US) because of inadequate training and unfamiliarity with the common US features encountered with mesenteric disease. (sajr.org.za)
  • 3] Mesothelioma is a malignant pleural or peritoneal tumor that rarely occurs in patients who have not been exposed to asbestos. (medscape.com)
  • Peritoneal inclusion cyst is a less common benign primary peritoneal tumor. (radiologyassistant.nl)
  • The sensitivity of the test results depends on the ability to completely lavage all regions of the peritoneal cavity and to detect cancer cells being shed into the peritoneal cavity by the tumor. (medscape.com)
  • The addition of contrast agents provides differential enhancement of tumor and normal soft tissues, thus further improving the delineation of hepatic and extrahepatic tumor (Figure 2). (cancernetwork.com)
  • Primary peritoneal carcinomas originate from the cells lining the peritoneum. (medscape.com)
  • Primary peritoneal cancer has been linked to certain variants of BRCA1/2 . (medscape.com)
  • Primary peritoneal carcinoma usually manifests as abdominal distention and diffuse nonspecific abdominal pain secondary to ascites. (medscape.com)
  • Gallium-67 (67Ga) citrate testing has been used to differentiate benign from malignant, asbestos-related pleural disease and to give a quantitative index of inflammatory activity. (medscape.com)
  • It is also known as benign multicystic mesothelioma . (radiologyassistant.nl)
  • More common diseases, such as benign asbestos-related pleural disease and metastatic adenocarcinoma , can look radiographically identical to mesothelioma. (medscape.com)
  • The radiographic findings of mesothelioma are nonspecific and are observed in other diseases, including metastatic carcinoma, lymphoma, and benign asbestos disease. (medscape.com)
  • In Peritoneum and Mesentery - part I: Anatomy the normal anatomy and physiology of the peritoneum and peritoneal cavity are discussed. (radiologyassistant.nl)
  • However, chest radiography remains the initial modality for the detection and characterization of pleural and parenchymal disease. (medscape.com)
  • CT is the imaging modality of choice to assess pleural disease and has shown sensitivity and specificity for identifying malignancy. (medscape.com)
  • Direct visualization of the peritoneal surfaces along with palpation of the abdominal contents is by far the most sensitive modality for detecting peritoneal cancer. (medscape.com)
  • A pelvic imaging study, if there is clinical suspicion of peritoneal carcinoma. (medscape.com)
  • The management of peritoneal carcinoma is similar to that of epithelial cancers of ovarian and fallopian tube, due to similar clinical characteristics. (medscape.com)
  • Standard imaging tests, including ultrasonography and helical CT scans, are notably insensitive for the detection of peritoneal tumors. (medscape.com)
  • Is the most common peritoneal solid mass resulting from ovarian or gastrointestinal cancer. (radiologyassistant.nl)
  • Women with higher risk of ovarian cancer also have increased risk of peritoneal cancer. (medscape.com)
  • Epithelial cancers of ovarian, fallopian tube, and peritoneal origin are known as epithelial ovarian cancer in clinical practice. (medscape.com)
  • Open abdominal exploration and palpation are extremely sensitive for 1- to 2-mm peritoneal nodules. (medscape.com)
  • Secondary peritoneal carcinomas usually invade locally or metastasize into the peritoneum from adjacent or remote organs. (medscape.com)
  • An assessment of the extent of disease is used to calculate compensation. (medscape.com)
  • therefore, disease extent is frequently underestimated in radiographs. (medscape.com)
  • Pseudomyxoma peritonei is less common, but looks quite similar to peritoneal carcinomatosis. (radiologyassistant.nl)
  • Nuclear medicine study has a limited role in the investigation of asbestos-related intrathoracic disease. (medscape.com)
  • Case studies of asbestos-related disease are illustrated in the images below. (medscape.com)