The majority of uterine smooth muscle tumors occur in the corpus, but the cervix, vaginal canal, broad ligament, and ovaries may also be involved. (medscape.com)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. (wikipedia.org)
A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. (curehunter.com)
[ 1 ] Intestinal leiomyosarcomas are mesenchymal tumors of smooth muscle origin. (medscape.com)
GISTs, however, have been shown to lack characteristics of smooth muscle tumors on histologic examination. (medscape.com)
Cardiac tumors are neoplasm grow in inner lining, muscle layer or pericardium surrounding the heart. (247homeopathy.com)
Smooth muscle tumors represent the second most common mural mesenchymal neoplasm in the gastrointestinal tract, but established criteria for prognostic assessment of these tumors are lacking. (elsevierpure.com)
A large cohort of surgically resected intramural gastrointestinal smooth muscle tumors from 31 institutions was analyzed to identify potential prognostic features. (elsevierpure.com)
the remainder includes mesenchymal and histiocytic tumors. (unicatt.it)
This review examines the cytohistological features of various nonepithelial and nonlymphoid tumors of the thyroid, including vascular lesions, neural tumors (including granular cell tumor and paraganglioma), smooth muscle tumors, solitary fibrous tumor, histiocytic neoplasms (eg, Langerhans cell histiocytosis and Rosai-Dorfman disease), and follicular dendritic cell sarcoma. (unicatt.it)
Their differential diagnosis is discussed, including recommendations to prevent the pitfall of mistaking these rare tumors for more common epithelial thyroid neoplasms. (unicatt.it)
A wide spectrum of mesenchymal tumors harboring ALK gene rearrangements has been identified outside the archetypal example of ALK-positive inflammatory myofibroblastic tumors. (yonsei.ac.kr)
To evaluate the molecular pathology of unusual ALK-positive mesenchymal tumors and their response to ALK-targeted treatments. (yonsei.ac.kr)
Seven patients with ALK-positive mesenchymal tumors, including inflammatory epithelioid cell sarcoma, undifferentiated sarcoma, histiocytic neoplasm, smooth muscle tumor of uncertain malignant potential (STUMP), and atypical fibrohistiocytic tumor, were included on the basis of aberrant ALK immunoexpression. (yonsei.ac.kr)
A glomus tumour (glomangioma, tumors of Popoff, or Barré-Masson syndrome) is a benign mesenchymal neoplasm composed of cells which resemble the modified smooth muscle cells of the normal glomus body (glomocytes) [1]. (jbstjournal.com)
Benign smooth muscle tumors, or leiomyomas, are common, well-circumscribed neoplasms that can arise from smooth muscle cells anywhere in the body, but are encountered most commonly in the uterus [1]. (peertechzpublications.org)
Perivascular epithelioid cell tumors (PEComas) are a rare group of mesenchymal neoplasms characterized by the presence of histologically and immunohistochemically distinctive perivascular epithelioid cells [ 1 ], which can occur in any part of the body. (biomedcentral.com)
Of these, inflammatory or pelioid pattern usually presents as a focal finding within the tumor, but very rarely, they become the predominant pattern [ 4 ], creating great diagnostic confusion with other tumors such as inflammatory myofibroblastic tumor (IMT), follicular dendritc cell (FDC) tumor and other hepatic mesenchymal neoplasms. (biomedcentral.com)
Chen, HY, Nguyen, TMT & Chang, IW 2021, ' Low-Grade Fibromatosis-Like Spindle Cell Carcinoma of the Breast: a Mimicker of Benign Mesenchymal Tumors ', Indian Journal of Surgery , vol. 83, pp. 535-538. (tmu.edu.tw)
Background: Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors that may mimic ovarian tumor on presurgical testing. (scirp.org)
While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
The differential diagnosis of a malignant effusion is accordingly broad, especially for the small round blue cell tumors that includes not only mesenchymal tumors, but also non-mesenchymal tumors, such as neuroblastoma and Wilms tumor. (cytojournal.com)
Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
The cause of TIO are usually small, slowly growing tumors of mesenchymal origin (phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) [ 5 , 7 - 10 ]. (hindawi.com)
Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract. (medscape.com)
Tumors with skeletal muscle differentiation and malignant Schwann cells are classified as a subtype or a histologic variant of MPNST [ 9 , 10 ] and are referred to as malignant triton tumor (MTT) [ 11 ]. (hindawi.com)
These tumors are diagnosed based on their typical clinical and histopathologic features and should not be confused with smooth muscle tumors even if they express SMA. (surgpath4u.com)
Lipoma is a benign mesenchymal neoplasm of soft tissue composed of mature adipocyte cells, being among the most common benign tumors. (bvsalud.org)
Some lesions of the oral cavity may not be genuine benign tumors, being herniations of the adipose cushion of the cheek mucosa 4 , a fact which alerts the professional responsible for the diagnosis to an understanding of the main clinical characteristics of this benign neoplasm. (bvsalud.org)
Differentiation4
Leiomyosarcomas are rare mesenchymal neoplasms characterized by a smooth muscle differentiation pattern. (oncotarget.com)
The tumor consists of sex cord-like and mesenchymal differentiation with various possible components, including Sertoli-like tubules, nested granulosa-like architecture, retiform growth, lipidized cells, Leydig-like cells, stromal cells with infiltrative growth, and solid sheets of smooth muscle-like cells. (cedars-sinai.edu)
Immunohistochemical study showed positivity for c-kit (CD117) and S-100 with neural and muscle differentiation present. (scirp.org)
Rhabdomyoblastic differentiation in a malignant peripheral nerve sheath tumor (MPNST) is termed malignant triton tumor (MTT), a rare neoplasm that poses a diagnostic dilemma in the differential diagnosis of neck masses and portends poor prognosis. (hindawi.com)
Tumours7
Sarcomas are rare tumours that arise from mesenchymal tissues and comprise 1% of all adult solid cancers [ 1 ]. (oncotarget.com)
Background: Perivascular epithelioid cell tumours (PEComas) are mesenchymal neoplasms with variable biological behaviour, ranging from benign to extremely aggressive diseases able to metastasize. (fortuneonline.org)
Primary leiomyogenic tumours have been reported in unusual locations where smooth muscle cells are usually absent, such as the sinonasal cavity. (bmj.com)
Subsequently, several research discovered that Pup1 is certainly a delicate immunohistochemical marker for GIST, getting portrayed in other mesenchymal tumours [25C27] rarely. (moonphase2018.com)
The primary differential medical diagnosis of GIST contains simple muscles tumours (leiomyoma and leiomyosarcoma), nerve sheath tumours (schwannoma and neurofibroma), inflammatory fibroid polyp and desmoid fibromatosis. (moonphase2018.com)
Furthermore, simple muscles tumours and nerve sheath tumours are positive for desmin and S100 proteins diffusely, respectively. (moonphase2018.com)
However, it really is known that tumours arising in the intestines are associated generally.CD34 could be expressed by 60C70% from the tumours, and simple muscles actin (SMA) appearance is detected in 30C40% from the situations. (moonphase2018.com)
Sarcoma3
The neoplastic cells expressed desmin, alpha-smooth muscle actin and CD10, compatible with endometrial stromal sarcoma tumor. (vin.com)
Kidney sarcoma is a rare malignant neoplasm that develops from one or more progenitor cell lines of the mesenchymal kidney tissue (muscle, fat, vascular elements). (medic-journal.com)
Conclusion: Undifferentiated pleomorphic sarcoma of the vulva is an uncommon mesenchymal neoplasm that presents diagnostic challenges. (journalcra.com)
However, it has been reported that they are uncommon in the oral cavity, representing between 15% and 20% of cases involving the head and neck, and between 1% and 5% of all benign neoplasms of the oral cavity. (bvsalud.org)
Tissue9
Leiomyosarcomas (LMS) are sarcomas that comprise spindle-cell neoplasms that develop from smooth muscle tissue and affect approximately 1 out of 100,000 Americans per year [ 2 - 4 ]. (oncotarget.com)
It is characterized by the presence of skeletal muscle tissue exhibiting embryonic features. (nih.gov)
Primary LMSs rarely occur in the oral and maxillofacial region, probably due to paucity of smooth muscle tissue in the area [1,3]. (peertechzpublications.org)
Angiomyolipoma (AML) is a rare mesenchymal neoplasm of the tumor, composed of a varying heterogeneous mixture of three tissue components: blood vessels, smooth muscle and adipose cells. (biomedcentral.com)
Subsequent microscopic examination and immunohistochemical analysis revealed a phosphaturic mesenchymal tumor mixed connective tissue variant (PMTMCT) showing a positive expression of somatostatin receptor 2A (SSTR2A), CD68, and Periostin. (hindawi.com)
Fibroblastic connective tissue nevus (FCTN) represents a rare and distinct benign cutaneous mesenchymal lesion of fibroblastic/myofibroblastic lineage, which broadens the spectrum of lesions presently recognized as connective tissue nevus. (lww.com)
Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue neoplasm with a poor prognosis. (hindawi.com)
The second explanation was more plausible, where neoplastic Schwann cells can transform into rhabdomyoblasts, suggesting the possibility of some mesenchymal tissue derivation from neuroectodermal cells. (hindawi.com)
Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Biopsy2
She underwent an endometrial biopsy, which demonstrated a müllerian mesenchymal neoplasm that could not be further classified based on histologic findings and immunostains. (cedars-sinai.edu)
Urodrill - a novel MRI-guided endoscopic biopsy technique to sample and molecularly classify muscle-invasive bladder cancer without fractionating the specimen during transurethral resection. (lu.se)
Uterine5
whether the tumor is a primary placental or uterine neoplasm. (biomedcentral.com)
A patient with a placental smooth muscle tumor that appears to be a uterine leiomyoma entrapped entirely in the placenta during its growth is presented. (biomedcentral.com)
In conclusion, uterine neoplasms in cats are rare, and the uterine tumor in the present case was an ESS. (vin.com)
UTROSCT is a rare uterine mesenchymal neoplasm that tends to occur in middle-aged women. (cedars-sinai.edu)
Spindle-cell1
On histopathological analysis, all the classic features were noted and diagnosis of a spindle cell neoplasm was made without any obscurity. (oldcitypublishing.com)
Pathology2
Detailed Pathology section describes common neoplasms in horses, cites research literature, and describes what is generally known about each condition. (vet-ebooks.com)
Classical diagnostic issues in gynecologic pathology have revolved around the potential for non-neoplastic diseases, benign neoplasms, and malignancies to mimic each other, and for different histotypes of malignancies to display morphologic and/or immunophenotypic overlap. (cme-video.com)
Poorly differentiated2
Electron microscopy demonstrated a poorly differentiated mesenchymal tumor with a multifocal giant cell component and evidence of neurosecretory-granules. (hindawi.com)
It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Actin3
The tumor cells were positive immunostaining for HMB-45, Melan-A, and smooth muscle actin. (biomedcentral.com)
An immunopanel of markers including pancytokeratin, p63, smooth muscle actin (SMA), CD10, and β-catenin was performed to establish the diagnosis and exclude other mimickers. (tmu.edu.tw)
The tumor cells stained intensely for vimentin (a mesenchymal marker), but no immunoreactivity for the Cytokeratin Pan (epithelial cells marker), Leukocyte Common Antigen (lymphoid cells marker), SMA (smooth muscle actin), Desmin (smooth and striated muscular cells marker), S100 (neuronal cells marker), CD34 (to identify vascular tumor), CD99 (synovial sarcoma marker) was detected. (journalcra.com)
Immunohistochemistry1
Upon immunohistochemistry (IHC), the tumor cells were positive for HMB45 and TFE3, focally positive for MelanA, while negative for muscle marker. (biomedcentral.com)
Lesions1
The differential diagnosis also included infectious and neoplastic disorders such as cellulitis, primary bone lesions (benign or malignant), lymphoproliferative or vascular disorders, and secondary neoplasms including sinus-related lesions or distant metastases. (reviewofophthalmology.com)
The neoplasms may be histologically the same or different, and may be found in the same or different sites. (lookformedical.com)
Fluorescence1
Chromosomes of the neoplasm were studied by the fluorescence in situ hybridization technique and the tumor was found to carry XX chromosomes. (biomedcentral.com)
Histiocytic1
The 3'-partners of ALK fusion were identified in 3 of 4 investigated patients as follows: PRKAR1A-ALK (ALK-positive histiocytic neoplasm), TNS1-ALK (STUMP), and KIF5B-ALK (ALK-positive atypical fibrohistiocytic tumor). (yonsei.ac.kr)
Mimic1
As malignant cells have a tendency to round up in body fluids these non-epithelial neoplasms can therefore mimic reactive mesothelial cells and metastatic adenocarcinoma. (cytojournal.com)
Leiomyomas2
They usually do not exhibit the whirling smooth muscle pattern of leiomyomas. (surgpath4u.com)
Because GISTs often looked like swirling fascicles of smooth muscle cells under the microscope, they were historically classified as leiomyomas or leiomyosarcomas. (surgpath4u.com)
Smooth8
GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal, or similar cells. (wikipedia.org)
1065 For example, some previous diagnoses of stomach and small bowel leiomyosarcomas (malignant tumor of smooth muscle) would be reclassified as GISTs on the basis of immunohistochemical staining. (wikipedia.org)
Though LMS may arise from any site in the body containing a smooth muscle layer, they most often occur in the uterus, the retroperitoneum, and the extremities [ 5 , 6 ]. (oncotarget.com)
A rare benign smooth muscle neoplasm involving the placental parenchyma is presented. (biomedcentral.com)
Microscopic evaluation of the uterus demonstrated multiple sites of ovoid and fusiform mesenchymal cell proliferation, atrophic endometrial glands, with deep smooth muscle infiltration. (vin.com)
Source of smooth muscle in the oral cavity may be the arterial tunica media, lingual duct, circumvallate papillae and pluripotential mesenchymal cells [1]. (peertechzpublications.org)
The most common type is the mixed type which comprises sheets of epithelioid muscle cells admixed with islands of adipocytes and abnormal vessels. (biomedcentral.com)
Co-expression of epithelial and muscle markers is common. (cedars-sinai.edu)
Exhibit2
Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
SCCAs are the most frequent neoplasms to exhibit this behavior, followed by adenoid cystic carcinoma (ACC), lymphoma, and rhabdomyosarcoma . (medscape.com)
Diagnosis2
Molecular investigation of ALK-positive mesenchymal neoplasms could allow for an accurate diagnosis and personalized treatment. (yonsei.ac.kr)
The location beneath the mylohyoid muscles and the expansion of the hyoid bone with chondroid calcification should suggest the correct diagnosis. (ajnr.org)
Cells8
The discovery is based on the use of mesenchymal stem cells and microcapsules made of polymeric compounds. (news-medical.net)
2019) Biomimetic drug delivery platforms based on mesenchymal stem cells impregnated with light-responsive submicron sized carriers. (news-medical.net)
Rhabdomyosarcoma is a neoplasm that develops from undifferentiated mesenchymal cells that have the capacity to differentiate into striated muscle. (reviewofophthalmology.com)
Structurally plump endothelial cells line a centrally coiled canal which is surrounded by longitudinal and circular muscle fibres containing rounded epithelial appearing glomus cells (glomocytes) [1,2]. (jbstjournal.com)
The histopathology was characterized by bland neoplastic spindle cells with mild or no nuclear atypia, mimicking a benign mesenchymal tumor. (tmu.edu.tw)
Mesenchymal cells are required for functional development of thymic epithelial cells. (jax.org)
A case study by Fukai et al of a patient with perineural spread of adenoid cystic carcinoma along the mandibular nerve suggested that progression of this lesion is associated with elevated expression of ephrin type-A receptor 2 and a transition of the tumor cells from an epithelial to a mesenchymal phenotype. (medscape.com)
A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
Renal1
The largest mass at the left of the retroperitoneum was 13 cm x 9 cm x 7 cm extended upwards to left kidney, renal artery and vein, abdominal aorta and psoas muscle and downwards to descending colon and reached pelvis where it appeared in contiguity with the homolateral external iliac artery. (fortuneonline.org)
Angiomyolipoma1
Hepatic angiomyolipoma is a rare, benign, hepatic mesenchymal neoplasm found in both males and females, and most commonly in adult females. (biomedcentral.com)
Skeletal muscle1
When they degenerate, leiomyomata may assume a red discoloration, called carneous degeneration (the nodule looks like skeletal muscle). (medscape.com)