• A breakthrough for the identification of the proteome of the presynaptic active zone was the successful employment of antibodies directed against a cytosolic epitope of membrane integral synaptic vesicle proteins for the immunopurification of synaptic vesicles docked to the presynaptic plasma membrane. (mdpi.com)
  • Non-collagenous proteins could be involved in the nucleation of calcium- and phosphate crystals (hydroxyapatite) and may also control the initial growth and orientation of the ionic nucleus. (intelligentdental.com)
  • Cation-transporting proteins that utilize the energy of ATP hydrolysis for the transport of CALCIUM. (jefferson.edu)
  • To solve this problem, the cell membrane contains proteins that are selective for unique, water soluble molecules. (wikibooks.org)
  • The transport may be active transport by carrier proteins with an energy source, or it may be facilitated diffusion or passive transport via channels. (wikibooks.org)
  • ATP13A3 is a member of the P-type ATPase family of proteins that transport a variety of cations across membranes. (nih.gov)
  • Approximately 40% of total calcium is bound to serum proteins, and 80% to 90% of this calcium is bound to albumin. (abdominalkey.com)
  • Chlorpromazine (CPZ), an inhibitor of calcium binding to proteins (calcium-dependent enzymes), and ethylene diamine tetra-acetic acid (EDTA), a chelator of Ca(2+), increased accumulation and efflux of EtBr at pH 8 but not at pH 5. (unl.pt)
  • As a divalent cation, calcium may not be very good at forming intramolecular complexes, but it can connect the molecules within those complexes, regulate pH, enable transport of specific ions, activate proteins, and act as a signaling agent. (chilledgrowlights.com)
  • The inhibition of influx is due in large part to the binding of metal ions to sulphydryl groups on transport proteins (ATPases), while the stimulation of efflux appears to be governed by the displacement of calcium from the intercellular tight junctions of the epithelial cells. (astm.org)
  • Mutant proteins in familial benign pemphigus create a loss of sensitivity to Ca 2+ and Mn 2+ ion binding and transport. (medscape.com)
  • The SERCA1 enzyme is found in skeletal muscle cells, specifically in the membrane of a structure called the sarcoplasmic reticulum . (medlineplus.gov)
  • The SERCA1 enzyme transports calcium ions from the cell into the sarcoplasmic reticulum, triggering muscle relaxation. (medlineplus.gov)
  • As a result, calcium ions are slow to enter the sarcoplasmic reticulum and muscle relaxation is delayed. (medlineplus.gov)
  • Mutations in the gene-encoding SERCA1, the fast-twitch skeletal muscle sarcoplasmic reticulum Ca2+ ATPase, are associated with Brody disease. (medlineplus.gov)
  • We describe a strategy to selectively inhibit, within tumor sites, the function of a critical intracellular protein, the sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump, whose proper function is required by all cell types for viability. (johnshopkins.edu)
  • Part of cellular calcium is sequestered in intracellular organelles, including endoplasmic reticulum, sarcoplasmic reticulum (SR) in muscle cells and in mitochondria. (abdominalkey.com)
  • The transitional type is involved in molecular transport whereas the sarcoplasmic reticulum is primarily concerned with how to " manage" calcium ions. (biologyonline.com)
  • en] The plasma membrane calcium/calmodulin-dependent ATPase (PMCA) is a ubiquitously expressed calcium-extruding enzymatic pump. (uni.lu)
  • In the majority of cells the main function of PMCA is as the only system to extrude calcium from the cytosol, however, in the excitable cells of the heart it has only a minor role in the bulk removal of calcium compared to the sodium-calcium exchanger. (uni.lu)
  • Of key interest in the heart is the functional interaction between the calcium/calmodulin-dependent enzyme neuronal nitric oxide synthase (nNOS) and isoform 4 of PMCA. (uni.lu)
  • Calcium moves across the plasma membrane through pathways such as the plasma membrane calcium ATPase (PMCA), or the sodium calcium exchanger, these are important in expelling calcium from the cell. (hstalks.com)
  • The very steep gradient is maintained by an energy-driven calcium pump, known as the plasma membrane Ca 2+ ATPase (PMCA). (abdominalkey.com)
  • Plasma membrane calcium-transporting ATPase 4 is an enzyme that in humans is encoded by the ATP2B4 gene. (wikipedia.org)
  • The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. (wikipedia.org)
  • This gene encodes the plasma membrane calcium ATPase isoform 4. (wikipedia.org)
  • Plasma membrane calcium ATPase and its relationship to nitric oxide signaling in the heart. (uni.lu)
  • The bone minerals calcium, phosphate and magnesium are all maintained at higher concentrations in utero to achieve adequate bone accretion. (frontiersin.org)
  • Passive and active transport of bone-minerals occurs across the placenta to achieve higher fetal concentration of calcium, phosphate, and magnesium compared to maternal levels. (frontiersin.org)
  • It was shown that COVID-19 patients revealed high serum levels of α-MSH as compared with healthy individuals but low serum levels of vitamin D, calcium, and magnesium which may be recommended as supplements for those patients to increase the innate immune response. (ukrbiochemjournal.org)
  • General scheme of plant transport processes and its regulation. (elte.hu)
  • 3. Uptake of calcium and its regulation. (elte.hu)
  • Also, significant discoveries including new embryological molecular genetic transcription factors, the role of active placental mineral transport, and hormone regulation factors have changed the understanding of calcium and phosphate homeostasis in the fetus and the newborn. (frontiersin.org)
  • The authors' data concerning ionic and membrane mechanisms of NO action on Ca 2+ -homeostasis of uterine myocytes, identification of nitric oxide in uterine smooth muscle mitochondria, biochemical characteristics of the NO-synthase reaction and the possible role of NO in the regulation of Ca 2+ transport in these subcellular structures and in the electron transport chain functioning are presented and discussed. (ukrbiochemjournal.org)
  • The calcium ion is essential to any physiologic phenomena, including preservation of the integrity of cellular membranes, neuromuscular activity, regulation of endocrine and exocrine secretory activities, blood coagulation, activation of the complement system, and bone metabolism. (abdominalkey.com)
  • this presentation is all about calcium metabolism and regulation in human body. (slideshare.net)
  • Age-related gene expression profiles of the short-lived model animals Caenorhabditis elegans and Drosophila melanogaster share a common adult-onset expression program of genes involved in mitochondrial metabolism, DNA repair, catabolism, peptidolysis and cellular transport 3 . (nature.com)
  • Calcium metabolism/ oral surgery courses /certified fixed orthodontic courses. (slideshare.net)
  • ACA2_ARATH Calcium-transporting ATPase 2, plasma membrane-type - Arabidopsis thaliana (Mouse-ear cress). (tcdb.org)
  • The lipid bilayer of cell membranes is impermeable to large and polar molecules but permeable to water molecules and other small uncharged molecules like O 2 and CO 2 . (wikibooks.org)
  • Function of endoplasmic reticulum calcium ATPase in innate immunity-mediated programmed cell death. (jefferson.edu)
  • The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. (wikipedia.org)
  • MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)
  • As you can see, the calcium ion is highly represented, and in fact, this messenger is recycled for many different purposes to mediate the actions (for example) of G protein-coupled receptors, receptor tyrosine kinases, voltage-operated calcium channels, among others. (hstalks.com)
  • Total serum calcium is divisible into protein-bound and ultrafiltrable (diffusible) calcium ( Fig. 6-1 ). (abdominalkey.com)
  • Variations in serum protein alter proportionately the concentration of the protein-bound and total serum calcium. (abdominalkey.com)
  • An increase in serum albumin concentration of 1 g/dL increases protein-bound calcium by 0.8 mg/dL, whereas an increase of 1 g/dL of globulin increases protein-bound calcium by 0.16 mg/dL. (abdominalkey.com)
  • Marked changes in serum sodium concentration also affect the protein binding of calcium. (abdominalkey.com)
  • Hyponatremia increases, whereas hypernatremia decreases protein-bound calcium. (abdominalkey.com)
  • Changes in pH also affect protein-bound calcium, and an increase or decrease of 0.1 pH increases or decreases protein-bound calcium by 0.12 mg/dL. (abdominalkey.com)
  • Orthologous to human VMP1 (vacuole membrane protein 1). (nih.gov)
  • An overall defect in keratinocyte adhesion appears to be secondary to a primary defect in a calcium pump protein, ATP2C1. (medscape.com)
  • Hailey-Hailey disease, or familial benign pemphigus, is hypothesized to result from a genetic defect in a calcium pump protein. (medscape.com)
  • Welcome to this lecture on extracellular calcium signaling. (hstalks.com)
  • In addition, the effects of halothane were assessed in the absence of extracellular calcium (Ca) with or without 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid, an intracellular Ca chelating agent. (asahq.org)
  • The normal concentration of cytosolic calcium is 100 nM/L, which is 10,000-fold lower than the concentration of extracellular calcium. (abdominalkey.com)
  • It can activate the InsP3 calcium channel on the endoplasmic reticular membrane, triggering the release of calcium from intracellular stores, leading to a calcium-influx of extracellular calcium. (fishersci.com)
  • These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. (wikipedia.org)
  • Its final common pathway may be a disturbance in myocyte calcium homeostasis. (medscape.com)
  • Care, A.D. (1997) Fetal calcium homeostasis. (scirp.org)
  • All of this transport activity is, of course, exceedingly important in shaping the intracellular calcium signal. (hstalks.com)
  • The ratio of fluorescence emission at 410 nM to that at 490 nM is used as an index of free intracellular calcium. (abdominalkey.com)
  • A major portion of the Ca 2+ ions are transported through a cellular route under the control of odontoblasts. (intelligentdental.com)
  • It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. (bvsalud.org)
  • Genomic discoveries have continued to provide new insights into the mechanisms facilitating transplacental bone mineral transport and unveil the causation of conditions previously thought to be idiopathic. (frontiersin.org)
  • The placental transfer of maternal calcium to the fetus represents a vital mechanism for fetal development and breast-milk production, yet little meaningful information is currently available regarding the biochemical mechanisms involved in this process. (scirp.org)
  • Once again, the use of different animal models as rodents, rabbit, sheep and bovine have demonstrate different mechanisms of calcium transport across the placenta and contribute to better understand its effects in both fetus and mother during the gestation. (scirp.org)
  • Odontoblasts maintain the Ca 2+ ion balance by transmembranic transport mechanisms, including Ca-ATPase, Na + exchangers and calcium channels. (intelligentdental.com)
  • The biochemical mechanisms of NO action on the myometrium contractile activity, the significance of NO in the physiological processes during pregnancy and labor, the importance of mitochondria as a reliable NO source in the smooth muscle and the possible ways of NO influence on Ca 2+ transport and bioenergetic processes in mitochondria are considered. (ukrbiochemjournal.org)
  • Therefore, we analysed stage-specific gradients of pH i and V mem as well as their dependence on specific ion-transport mechanisms. (biomedcentral.com)
  • While the inhibition of Na + /H + -exchangers (NHE) and amiloride-sensitive Na + -channels or of V-ATPases resulted in relative acidification, inhibiting the other ion-transport mechanisms led to relative alkalisation. (biomedcentral.com)
  • V mem was most efficiently hyperpolarised by inhibiting voltage-dependent L-type Ca 2+ -channels or ATP-sensitive K + -channels, whereas the impact of the other ion-transport mechanisms was smaller. (biomedcentral.com)
  • Our data show that in the Drosophila follicle-cell epithelium stage-specific pH i - and V mem -gradients develop which result from the activity of several ion-transport mechanisms. (biomedcentral.com)
  • Permeability transition pore (mPTP) opening was studied under energized and deenergized conditions in rat liver mitochondria, and the effect of membrane depolarization on mPTP activity was evaluated. (ukrbiochemjournal.org)
  • Classically the V-ATPase is a proton pump that ensures the acidification of intracellular compartments, including those destined for secretion and notably synaptic vesicles. (anr.fr)
  • Because calcium ions (Ca(2+)) are important for membrane transport channels and the activity of ATPases that provide energy functions, the role of Ca(2+) in the extrusion of an efflux pump substrate under conditions that challenge the bacterium was investigated. (unl.pt)
  • Because at pH 8 hydrolysis of ATP is favoured and contributes protons for activation of the AcrAB-TolC efflux pump, CPZ is suspected of having its effects on accumulation/efflux of EtBr by indirectly affecting ATPase activity that is dependent upon Ca(2+). (unl.pt)
  • [ 6 ] This gene defect is similar to the genetic defect in Darier disease , which also is a calcium pump defect, ATP2A2 . (medscape.com)
  • ii) co-operating with SNAREs to promote synaptic vesicle fusion at the plasma membrane. (anr.fr)
  • Without the ribosomes, the endoplasmic reticulum is most likely involved in other cellular processes, e.g., synthesizing lipids, detoxifying or metabolizing drugs and toxins, or regulating calcium ions. (biologyonline.com)
  • Plasma membrane enriched preparations obtained from cultured human skin fibroblasts by differential centrifugation and sucrose density centrifugation techniques were found to contain a Mg2+-dependent Ca2+-stimulated ATPase activity. (nih.gov)
  • The (Mg2+ + Ca2+)-ATPase activity of both crude and plasma membrane enriched preparations of cultured fibroblasts from cystic fibrosis patients was significantly reduced compared to that activity observed in age-matched controls. (nih.gov)
  • This study corroborates our previous observations made in crude homogenate preparations of fibroblasts and indicates another cell type where (Mg2+ + Ca2+)-ATPase activity may be altered in cystic fibrosis. (nih.gov)
  • Expression of the sarco/endoplasmic Ca(2+)-ATPase, SERCA1a, in fibroblasts induces the formation of organelle membrane arrays. (jefferson.edu)
  • Sweiry, J.H. and Yudi-levich, D.L. (1984) Asymmetric calcium influx and efflux at maternal and fetal sides of the guinea-pig placenta: Kinetics and specificity. (scirp.org)
  • An estimate of mPTP activity by cyclosporine-sensitive Ca 2+ transport under energized and deenergized conditions have shown that membrane depolarization by protonophore CCCP essentially increased initial rate ( V 0 ), at simultaneous decrease of the half-time ( t 1/2 ) of Ca 2+ efflux, which indicated mPTP activation, as compared to energized mitochondria. (ukrbiochemjournal.org)
  • Role of calcium in the efflux system of Escherichia coli. (unl.pt)
  • http://www.ncbi.nlm.nih.gov/pubmed/?term=Role+of+calcium+in+the+efflux+system+of+Escherichia+coli. (unl.pt)
  • Real-time accumulation and efflux of ethidium bromide (EtBr) by E. coli K-12 AG100 strain [argE3 thi-1 rpsL xyl mtl Δ(gal-uvrB) supE44] was determined by a semi-automated fluorometric method in the presence and absence of Ca(2+) and agents that are known to inhibit access of calcium to enzymes that provide energy. (unl.pt)
  • Cytosolic calcium upregulation is implicated in DMD cardiomyopathy. (bvsalud.org)
  • Cytosolic calcium can be measured by loading the tested cells with a fluorescent probe such as indo-1-acetoxymethyl ester and exciting the cells at 350 nM. (abdominalkey.com)
  • In certain types of cells, a Na + /Ca 2+ exchanger, energized by a Na + -gradient, helps drive cytosolic calcium into the extracellular space. (abdominalkey.com)
  • ATP2C1 encodes the secretory pathway Ca 2+ /Mn2 ATPase (hSPCA1). (medscape.com)
  • The gene ATP2C1 encodes the human secretory pathway Ca ++ -ATPase hSPCA1, which is dysfunctional and causes abnormal calcium release from the Golgi apparatus and endoplasmic reticulum. (medscape.com)
  • In addition to synthesizing surfactant, alveolar type II cells actively transport sodium (Na) from the alveolar space to the interstitium. (asahq.org)
  • The specific activity of the (Mg2+ + Ca2+)-ATPase present was 4-5-fold higher than that present in crude membrane preparations and 80-100-fold higher than that present in homogenates. (nih.gov)
  • The mutation of Pro789 to Leu reduces the activity of the fast-twitch skeletal muscle sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA1) and is associated with Brody disease. (medlineplus.gov)
  • Ca 2+ added from the outer side of mitochondrial membrane produced dual effect on mPTP activity: activation at the onset of depolarization, but consequent promotion of mPTP closure. (ukrbiochemjournal.org)
  • As a result of weathering and microbial activity, these rocks slowly dissolve, releasing calcium ions. (chilledgrowlights.com)
  • ATP13A3 is a major component of the enigmatic mammalian polyamine transport system. (nih.gov)
  • This article will guide clinicians through an updated review of calcium and phosphate physiology, then review specific conditions pertinent to successful neonatal care. (frontiersin.org)
  • 4. A thorough understanding of the topic is essential to correct diagnosis and treatment of disorders of calcium and phosphate in the newborn. (frontiersin.org)
  • Effect of Lysophosphatidylcholine on ATP and ρ-Nitrophenyl Phosphate Hydrolysis by the Plasma Membrane H+-ATPase from Soybean Hypocotyls [J]. J Integr Plant Biol. (jipb.net)
  • The calcium complexes are formed with bicarbonate, phosphate, and acetate. (abdominalkey.com)
  • The ATP2A1 gene provides instructions for making an enzyme called sarco(endo)plasmic reticulum calcium-ATPase 1 (SERCA1). (medlineplus.gov)
  • Treatment involves lifestyle changes and medications, including diuretics, angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, and calcium channel blockers. (msdmanuals.com)
  • Titration" of Ca 2+ transport by adding RR at different times from the onset of depolarization showed that depolarization dramatically reduced "life span" of mPTP as compared to energized mitochondria, which agreed with the kinetic characteristics of CsA-sensitive Ca 2+ transport after the abolition of ΔΨ m . (ukrbiochemjournal.org)
  • Based on the experiments, it was concluded that mitochondrial energization was required for prolonged mPTP functioning in sub-conductance states, whereas membrane depolarization promoted the transition of mPTP to inactive state during calcium release from mitochondria. (ukrbiochemjournal.org)
  • thus calcium concentration is higher in fetus than in maternal blood. (scirp.org)
  • Despite conflicting reports, several investigators agreed that calcium concentration in the fetal blood is mainly regulated by fetal parathyroid hormone and plasma concentration of vitamin D3, a metabolite that plays a key role in calcium transport through the syncytial cells. (scirp.org)
  • However, an interesting corollary of these plasma membrane fluxes is that they can potentially lead to significant alterations in local calcium concentration at the extracellular face of the cell. (hstalks.com)
  • Understanding free energy is the heart of understanding how molecules are transported and/or behave in a concentration gradient. (wikibooks.org)
  • When ΔG is positive the transport is active, an input of energy is needed to move a molecule up a concentration gradient, contrary to ΔG being negative the transport is passive, which means that such molecules will pass through a membrane down their own gradient, simple diffusion. (wikibooks.org)
  • Diffusion is the process by which molecules migrate over the cell membrane from areas of higher concentration to areas of lower concentration. (wikibooks.org)
  • Water will move from an area with a higher concentration of water to the other side of the membrane with a lower concentration of water. (wikibooks.org)
  • Thus, it is obvious that changes in total serum calcium concentration cannot be used for the assessment of the effect on bound calcium concentration unless the changes in albumin and globulin concentrations also are determined. (abdominalkey.com)
  • Thus, serum water is forced across the membrane, and the ultrafiltrate is analyzed for calcium concentration and then corrected for total serum solids. (abdominalkey.com)
  • Serum-ionized calcium concentration in normal subjects ranges from 4.0 to 4.9 mg/dL, or 47% of total serum calcium. (abdominalkey.com)
  • The samples have to be handled anaerobically because changes in pH alter the concentration of ionized calcium. (abdominalkey.com)
  • The synthesis and secretion of prostaglandins I 2 and E 2 and the normal function of the stretch receptors are dependent on the intracellular ionized calcium concentration. (medscape.com)
  • Calcium-Transporting ATPases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
  • The availability of free energy is one of the factors that determine if a molecule will move across a membrane, the other being the permeability of the molecule in the lipid bilayer. (wikibooks.org)
  • These junctions consist of calcium-binding transmembrane glycoproteins, which contribute to cellular adhesion. (medscape.com)
  • Smith, C.H. and Moe, A.J. (1992) Nutrient transport pathways across the epithelium of the placenta. (scirp.org)
  • [1,2] Recently, however, halothane was shown to inhibit Na/calcium (Ca) exchanger and Ca channels in heart cells [3] and to decrease ion transport in canine tracheal epithelium, an effect that may contribute to decreased mucous clearance in the perioperative period. (asahq.org)
  • The Drosophila follicle-cell epithelium provides an appropriate model system for studying the potential role of electrochemical signals, like intracellular pH (pH i ) and membrane potential (V mem ), during development. (biomedcentral.com)
  • The large convection requirement for respiration in water and the extensive areas of exposed membrane on the branchial epithelium, ensure that the gill is also a major site of interaction with waterborne contaminants. (astm.org)
  • Respectively, in vitro, freezing and thawing serum samples may decrease the binding of calcium as well. (abdominalkey.com)
  • There are many reports of pesticides inhibiting ATPases in vitro , as well as some equivocal information that such effects occur in vivo at relevant concentrations. (astm.org)
  • Ca-ATPases, Ca-channels. (elte.hu)
  • Calcium can enter through pathways such as store-operated, voltage-operated, or receptor-operated calcium channels. (hstalks.com)
  • They differ from CALCIUM CHANNELS which allow calcium to pass through a membrane without the use of energy. (jefferson.edu)
  • To minor extents, both pH i -gradients were enhanced and both V mem -gradients were reduced by inhibiting voltage-dependent L-type Ca 2+ -channels, whereas only both pH i -gradients were reduced (increasing acidification) by inhibiting V-ATPases or NHE and Na + -channels. (biomedcentral.com)
  • The conformation of H,K-ATPase determines the nucleoside triphosphate (NTP) selectivity for active proton transport. (jefferson.edu)
  • Influence of K+ on the Coupling Between ATP Hydrolysis and Proton Transport by the Plasma Membrane H+-ATPase from Soybean Hypocotyls [J]. J Integr Plant Biol. (jipb.net)
  • To achieve targeted inhibition, we took advantage of the unique expression of the carboxypeptidase prostate-specific membrane antigen (PSMA) by tumor endothelial cells within the microenvironment of solid tumors. (johnshopkins.edu)
  • Hosking, D.J. (1996) Calcium ho-meostasis in pregnancy. (scirp.org)
  • Wooding, F.B.P., Morgan, G., Jones, G.V. and Care, A.D. (1996) Calcium transport and the localization of calbidin- D9K in the ruminant placenta during the second half of pregnancy. (scirp.org)
  • Another distinctive feature of a cellular structure regarded as an "organelle" is when it has a biological membrane that compartmentalizes its contents. (biologyonline.com)
  • A 2009 study has shown that the calcium content of basal keratinocytes is lower than in normal skin and that transition of keratin 14 to 10 is abnormal. (medscape.com)
  • Fetal blood calcium concentrations are maintained ~0.3-0.5 mmol/L higher than in maternal circulation, with the placenta transporting 100-150 mg/kg/day of calcium during the third trimester ( 4 - 6 ). (frontiersin.org)
  • Studies of calcium transfer across the placenta have been reviewed because of the physiological and nutritional importance of this mineral during pregnancy, especially in order to better understand its contribution to development of the fetal skeleton. (scirp.org)
  • Brunette, M.G. (1988) Calcium transport through the placenta. (scirp.org)
  • Husain, S.M. and Mughal, M.Z. (1992) Mineral transport across the placenta. (scirp.org)
  • Stulc, J. and Stulcová, B. (1986) Transport of calcium by the placenta of the rat. (scirp.org)
  • Weatherley, A.J., Ross, R., Pickard, D.W. and Care, A.D. (1983) The transfer of calcium during perfusion of the placenta in intact and thyroparathyroidectomized sheep. (scirp.org)
  • The odontoblastic plasma membrane Ca 2+ pumps, present in mineralizing dentin, may play a role in calcium transport and mineralization. (intelligentdental.com)
  • Their matrix is acidified through the action of proton pumps such as a vacuolar proton ATPase and a vacuolar proton pyrophosphatase. (uni-konstanz.de)
  • The calcium uptake occurs through a Ca 2+ /H + counter transporting ATPase located in the membrane of the organelle. (uni-konstanz.de)
  • At the molecular level we will dissect interactions between the V-ATPase membrane sector and the SNARE membrane fusion machinery and design probes to assess their functional relevance. (anr.fr)
  • Na transport was then evaluated by direct measurement of radiolabeled ions uptake. (asahq.org)
  • The amount of complexed calcium is measured indirectly by subtracting the ionized calcium (47%) from the ultrafiltrable calcium (60%) and thus equals about 13% of total serum calcium. (abdominalkey.com)