• molecule
  • Hydrolyzing ATP provides energy (free energy) as [ATP]/[ADP] falls to equilibrium- 57 kJ/mol, or 590 mV, assuming a single ATP molecule gives all it's energy to a single charge (the calculation is correct, but I can't account for the discrepancy with the resting potential). (physicsforums.com)
  • This molecule (dye) intercalates among the lipophilic part of biological membranes. (wikipedia.org)
  • extracellular
  • Removal of the C-terminal GYDQL lysosomal sorting motif causes cystinosin to migrate to the plasma membrane with the intralysosomal face of cystinosin facing the extracellular medium. (wikipedia.org)
  • ATPase
  • The proton motive force (pmf) across the lysosomal membrane is generated by a V-type ATPase which hydrolyzes cytoplasmic ATP to pump protons into the lysosomal lumen. (wikipedia.org)
  • proteins
  • The membrane potential is negative because usually cells have a net negative charge due to leakiness of potassium channels and the large size of negatively charged macromolecules such as proteins and RNA. (academickids.com)
  • continuously
  • On the other hand, it has been continuously reported the existence of the membrane potential inexplicable by the GHK equation by a small number of researchers [ 1 , 2 ]. (mdpi.com)
  • probes
  • I would like to know if anyone has experience with fluorecent probes for measuring membrane potential. (bio.net)
  • Fast-response probes: These are amphiphilic membrane staining dyes which usually have a pair of hydrocarbon chains acting as membrane anchors and a hydrophilic group which aligns the chromophore perpendicular to the membrane/aqueous interface. (wikipedia.org)
  • action potential initiation
  • We argue here that one can retain this highly detailed input structure while dramatically reducing the overall system dimension if one is content to accurately reproduce the associated membrane potential at a small number of places, e.g., at the site of action potential initiation, under subthreshold stimulation. (pubmedcentralcanada.ca)
  • Such multisite recordings may provide precise information on action potential initiation and propagation (including direction and velocity), and on the entire branching structure of a neuron. (wikipedia.org)