Galectin-1 is a ß-galactoside-binding lectin, ubiquitously expressed in stromal, epithelial, and different subsets of immune cells. (bvsalud.org)
Members contain viscotoxin (5 kDa basic polypeptides related to thionins), beta-galactoside- and N-acetyl-D-galactosamine-specific lectin II (60 kDa), and polysaccharides. (medindex.am)
Beta-galactoside2
ST3 beta-galactoside alpha-2,3-sialyltransferase 3, also known as ST3GAL3, is a protein which in humans is encoded by the ST3GAL3 gene. (wikipedia.org)
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. (ss-tiles.com)
Proteins5
Galectin-1 is the prototype member of the galectin family which shares specificity with ß-galactoside containing proteins and lipids. (bvsalud.org)
2011). Such important properties derive from the specific characteristics of legume proteins, carbohydrates and lipids, and also from several non-nutritional compounds like polyphenols, phytic acid or ¿-galactoside oligosaccharides. (ugr.es)
They were initially de- scribed in the electric eel, Electrophorus electri- cus , as low-molecular-weight, -galactoside- binding, soluble proteins (electrolectins) [1]. (fdocuments.net)
In contrast to this functional homology, the SalA and SalB proteins, members of family 3 of the glycosyl hydrolases, show a low degree of amino acid similarity. (lookformedical.com)
Galectins form a family of carbohydrate-binding proteins defined by their affinity for beta-galactosides containing glycoconjugates. (shengsci.com)
Galectin family members2
Galectin-9 (Gal-9) can be a member from the galectin family members that selectively binds to β-galactoside [13]. (bioxorio.com)
This is particularly true for galectin family members because changes in their expression levels correlate with alterations in cancer cell growth, apoptosis, and cell-cell and cell-matrix interactions. (fdocuments.net)
Oligosaccharides1
The identity and quantity of and effect of processing on raffinose oligosaccharides in raw, mature seeds of lima beans (Phaseolus lunatus), pigeon peas (Cajanus cajan), African yam beans (Sphenostylis sternocarpa) and jackbeans (Canavalia ensiformis) were investigated. (researchgate.net)
Galactose5
Subsequently, several groups identified new members of the galectin family in protein extracts obtained from various tissues by using their ability to bind galactose residues on rabbit erythrocytes and cloning approaches based on sequence homology. (fdocuments.net)
Subfamily AA5_2 contains galactose 6-oxidases ( EC 1.1.3.9 ), which oxidize the C-6 hydroxyl of diverse galactosides to the corresponding aldehyde [ 4 , 5 , 6 ]. (cazypedia.org)
The first biochemically characterized member of AA5 was the galactose 6-oxidase from the phytopathogenic fungus Fusarium graminearum (previously known as Polyporus circinatus and Cladobotryum (Dactylium) dendroides [ 11 ]), which was originally reported in 1959 following isolation from cultures [ 12 , 13 ]. (cazypedia.org)
Subsequently, the Fusarium graminearum galactose 6-oxidase became the defining member of AA5_2 [ 2 ]. (cazypedia.org)
The archetypal CRO and AA5 member is the Fusarium graminearum galactose 6-oxidase ( Fgr GalOx), which catalyzes the regioselective oxidation of the C6-hydroxyl group on the monosaccharide galactose ( EC 1.3.3.7 ) [ 12 , 13 ]. (cazypedia.org)
Affinity1
In 1994, a joint effort by several investigators in the field led to a new nomenclature in which the term "galectins" was used to define lectins with an affinity for - galactosides and with sequence similarity in the carbohydrate-binding site [3]. (fdocuments.net)
Legume1
Effects of legume protein hydrolyzates on lipid metabolism in an obese rat experimental model. (ugr.es)
Galectins1
Expression of galectins in normal lymphoid cells Each member of the galectin family exhibits a specific expression pattern in distinct tissues, and galectin expression is regulated during development. (fdocuments.net)
Treatments1
Interferon- α and more recently ipilimumab have been proposed as adjuvant treatments but their effect on survival is still a matter of debate. (hindawi.com)
Compounds3
The AA5_1 members are generally known as glyoxal oxidases ( EC 1.2.3.15 ), characterized members of which typically accept a range of simple aldehydes, α-hydroxycarbonyl, and α-dicarbonyl compounds as substrates, with the highest activities observed on glyoxal, methylglyoxal and glycolaldehyde [ 1 , 14 , 18 , 19 , 20 ]. (cazypedia.org)
A survey of agricultural technologies influencing the biosynthesis and accumulation of phenolic compounds in crop plants is presented, including observations on the effects of light, temperature, mineral nutrition, water management, grafting, elevated atmospheric CO 2 , growth and differentiation of the plant and application of elicitors, stimulating agents and plant activators. (mdpi.com)
The LC-MS-MS results showed that eight anthocyanin compounds, including cyanidin 3- O -glucoside, cyanidin 3- O -galactoside, malvidin 3- O -galactoside, and malvidin 3- O -glucoside, were differentially enriched in red-pigmented tissues of the petals, whereas most of these metabolites were undetected in white tissues of the petals. (biomedcentral.com)
Inhibitory1
Immunomodulatory functions have been ascribed to endogenous galectin-1 due to its induction of T cell apoptosis, inhibitory effects of neutrophils and T cell trafficking. (bvsalud.org)
Protein4
This protein is a member of glycosyltransferase family 29. (wikipedia.org)
By means of oligonucleotide microarray and RNA interference, we reveal that the sensitizing effect of IFN-β was possibly due to attenuation of MGMT expression via induction of the protein p53. (aacrjournals.org)
This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. (utsouthwestern.edu)
The current prolonged berry withering experiment revealed the timing of metabolite interconversions in the central metabolism and provided critical clues that link the concentration effect, protein degradation, and the onset of stress-like conditions in drying berries. (oeno-one.eu)
Seeds1
Cooking unsoaked seeds brought about a greater reduction in the total alpha-galactoside content than soaking for nine hours. (researchgate.net)
Arbutin4
Lipid composition determines the effects of arbutin on the stability of membranes. (lookformedical.com)
Twenty percent MGDG in EPC bilayers completely inhibited the fusogenic effect of arbutin. (lookformedical.com)
The effect of arbutin on lipid order was limited to the interfacial region of the membranes and was not evident in the hydrophobic core region. (lookformedical.com)
In UVB-irradiated human fibroblast cells, gallic acid glucoside lowered matrix metalloproteinase-1 levels and increased the collagen content, which was indicative of a stronger anti-aging effect than that of gallic acid or arbutin. (springeropen.com)
Antioxidant2
Legumes represent an excellent source of essential nutrients and exhibit a variety of health effects related to their antioxidant (Doblado, Frías, & Vidal-Valverde, 2007) and hypolipidemic properties (Hermsdorff et al. (ugr.es)
In addition to these nutritional properties, lupin also features beneficial functional properties such as antioxidant or hypocholesterolemic effects (Martínez-Villaluenga et al. (ugr.es)
Genus3
Similar to the other members belonging to this genus, sheep sorrel is also a little laxative and has the potential to be a long-term and effective remedy for chronic ailments , especially those related to the gastro-intestinal tract. (herbs2000.com)
and there is good reason to believe that the members of the genus are descended from bipedal dinosaurs specially adapted for locomotion on land. (google.co.in)
Sindbis virus (SINV), a member of the Western equine encephalomyelitis virus complex of the genus Alphavirus in the family Togaviridae , was first isolated in 1952 in the Nile River delta in Egypt from a pool of Culex pipiens and Cx . (cdc.gov)
Content3
greater reduction in the total α -galactoside content than soaking for nine hours. (researchgate.net)
Down-regulating the content of TXNIP decreased the effect of Gal-3 on neuroinflammation in in vitro model. (silverchair.com)
The skin-whitening and anti-aging effects exerted by matrix metalloproteinase-1 (MMP-1) and collagen content were determined as well. (springeropen.com)
Lipid1
The nonbilayer lipid egg phosphatidylethanolamine (EPE) had an effect similar to that of MGDG, but was much less effective, even at concentrations up to 80% in EPC membranes. (lookformedical.com)
Family members1
Thus, our work systematically reviewed the emerging role of GFRα family members in cancers, and provided novel insights for further researches. (medsci.org)
Composition1
This cross-sectional study determined the phenolic composition of an over-the-counter cranberry juice (CBJ) with high-performance liquid chromatography and examined the effects of low- and normal-calorie CBJ formulations on the postprandial glycemic response in healthy humans. (cranberryinstitute.org)
Juice1
This is an important detoxifying herb and the freshly obtained juice of the plants' leaves has a distinct diuretic effect. (herbs2000.com)
Side effects3
However, some patients cannot be treated with this therapy due to comorbidities and severe inflammatory side effects. (bvsalud.org)
Musk has directly contributed to Republican Sen. Sleepiness, deterioration in motor skills and ataxia were common side effects in children with tuberous sclerosis treated with nitrazepam. (theweetrio.com)
Studies and clinical trials comparing dipropanoylmorphine to morphine have produced results that indicate the incidence of side-effects are far more common with morphine. (theweetrio.com)
Cells2
Since FA cells are defective in DNA repair, we hypothesized that FA hematopoietic stem and progenitor cells (HSPCs) might express DNA damage-associated stress molecules such as natural killer group 2 member D ligands (NKG2D-Ls). (bvsalud.org)
effect had not been seen in nude mice indicating the participation of T cells in galectin-9-mediated success prolongation. (bioxorio.com)
Primary2
The CBJ used in this study contained seven phenolic acids, with 3- and 5-caffeoylquinic acid being the primary components, and 15 flavonol glycosides, with myricetin-3-galactoside and quercetin-3-galactoside being the most prevalent. (cranberryinstitute.org)
An apparent distinction between the AA5_1 and AA5_2 subfamilies is that while AA5_1 enzymes catalyze the oxidation of aldehydes to carboxylic acids [ 1 ], AA5_2 members oxidize primary alcohols to the corresponding aldehyde (and, in some instances, also oxidize the aldehyde to the acid, albeit much more slowly) [ 4 , 22 ]. (cazypedia.org)
Studies1
Many research studies have highlighted the positive effects of natural flavonoids on chronic diseases, including PCa. (mdpi.com)
Plant3
In effect, there is sufficient clinical evidence regarding the use of this plant for treating sinusitis. (herbs2000.com)
In contrast to their fungal and bacterial counterparts, plant AA5 members do not fall within the two defined subfamilies. (cazypedia.org)
The continuing development of this proposed program will be fueled through partnerships of Loving Garland Green members with other community groups such as Keep Garland Beautiful and Habitat for Humanity and City of Garland Departments such as the Neighborhood Vitality Department, our water department, our environmental waste department, our Parks and Recreation Department, etc. (bubblelife.com)
Western1
Histological assessment, ELISA and Western blotting were conducted to evaluate the effects of Gal-3 upon the SCI model. (silverchair.com)
Human1
It was delayed in 1983 because animal trials produced intramyelinic edema, however, the effects were not apparent in human trials so the drug Where To Purchase Modafinil 200mg Canada design continued. (theweetrio.com)
Model2
ROS reduced the effect of Gal-3 on oxidative stress in in vitro model. (silverchair.com)
Suppressing the level of NLRP3 could weaken the effect of Gal-3 on neuroinflammation in in vitro model. (silverchair.com)