Hereditary Breast and Ovarian Cancer SyndromeOvarian NeoplasmsGenes, BRCA1BRCA2 ProteinBRCA1 ProteinGenes, BRCA2MelanomaNeoplastic Syndromes, HereditaryGenetic TestingGenetic CounselingGerm-Line MutationSyndromeBreast NeoplasmsPedigreeGenes, DominantGenetic Predisposition to DiseaseMutationBreastHeterozygotePolycystic Kidney, Autosomal DominantDNA Mutational AnalysisNeoplasm ProteinsMelanoma, ExperimentalNeoplasms, Glandular and EpithelialFounder EffectFamily HealthBreast Neoplasms, MaleGenetic LinkageAge of OnsetCell Line, TumorSkin NeoplasmsGene Expression Regulation, NeoplasticColorectal Neoplasms, Hereditary Nonpolyposisvon Hippel-Lindau DiseaseDNA, NeoplasmRisk FactorsExonsPhenotypeCarcinoma, Ductal, BreastMastectomyGenotypeFamilyBreast Diseases