AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHealth Care
ConjunctivaMelanomaConjunctival DiseasesConjunctival NeoplasmsConjunctivitisMelanoma, ExperimentalPterygiumSkin NeoplasmsConjunctivitis, AllergicPemphigoid, Benign Mucous MembraneEyelidsUveal NeoplasmsCorneaTearsEye NeoplasmsBlepharitisMelanoma, Amelanoticgp100 Melanoma AntigenNevus, PigmentedMelanosisLacrimal ApparatusGoblet CellsDry Eye SyndromesKeratoconjunctivitisOphthalmologic Surgical ProceduresChoroid NeoplasmsEye DiseasesLimbus CorneaeEyelid NeoplasmsScleraEye Infections, ParasiticTrachomaOphthalmic SolutionsUveaOphthalmic NerveConjunctivitis, BacterialEpithelium, CornealEyeMonophenol MonooxygenaseMART-1 AntigenProto-Oncogene Proteins B-rafKeratoconjunctivitis SiccaScleral DiseasesMelanoma-Specific AntigensCorneal DiseasesCell Line, TumorImmunoenzyme TechniquesEye EnucleationAntigens, NeoplasmAmbrosiaDysplastic Nevus SyndromeFluorescent Antibody Technique, IndirectTumor Cells, CulturedAdministration, TopicalMelaninsNeoplasm MetastasisRabbitsEpitheliumRose BengalReverse Transcriptase Polymerase Chain ReactionEyelid DiseasesPallorImmunohistochemistryEyelashesConjunctivitis, InclusionPharmaceutic AidsRhinosporidiosisKeratin-12Neoplasm ProteinsMucous MembraneKeratosis, SeborrheicAnterior Eye SegmentStevens-Johnson SyndromeEpithelial CellsRNA, MessengerRhinosporidiumLacrimal Apparatus DiseasesMucin 5ACKeratitisTrabeculectomyMucinsEye BurnsDermoscopyBlisterOrbital NeoplasmsBenzalkonium CompoundsKeratin-4Neoplasm TransplantationConjunctivitis, ViralAmnionS100 ProteinsEye InjuriesMyiasisGene Expression Regulation, NeoplasticMicrophthalmia-Associated Transcription FactorAntibodies, MonoclonalMeibomian GlandsStaining and LabelingMice, Inbred C57BLCell Proliferation
OcularTumorsCorneaMetastasisCarcinomaBulbarTumorCutaneous melanomaNevusSquamousChoroidMelanocytesNeoplasiaCases of conjunctival melanomaRisk of progression to melanomaLesions of the conjunctivaLymphomaAtypiaPersonal history of melanomaCells that produce melaninCornealChoroidal melanomasMelanocyticInvasive melanomaAdultsTypes of melanomaPosterior uvealOccurNeviIrisIntraepithelialMucosal melanomaIntraocular melanomaMetastaticOrbitUveal melanomasPrognostic factorsDiagnosisDiffuseAnterior uvealCancerPatientsEyeballLesionExcisionCiliary body melanomasPrimary acquiredNeoplasms
Ocular10
  • 3 ] Ocular melanoma is the most common cancer of the eye, with approximately 2,000 cases diagnosed annually. (cancer.gov)
  • We have achieved international recognition for our research and treatment of ocular melanoma. (uclahealth.org)
  • Specially trained ophthalmologists called ocular oncologists can diagnose and treat eye melanoma. (cancer.net)
  • Then, three months after proton beam therapy, ocular surface melanoma almost subsided and the clear cornea allowed visualization of the intraocular lens inside the eye. (elsevierpure.com)
  • Ocular melanoma starts inside the eyeball. (eyes-road.eu)
  • However, The multicenter, international, Collaborative Ocular Melanoma Study taught us that removal of the eye was not necessary for moderately sized choroidal melanomas. (eyecancercure.com)
  • Until we have a treatment for metastatic ocular melanoma, destruction of the intraocular tumor will be the best way to prevent and thus "treat" metastasis. (eyecancercure.com)
  • When faced with a possible diagnosis of uveal melanoma, you can turn to our experienced, board-certified ocular oncologist at Retina Consultants of Texas. (retinaconsultantstexas.com)
  • Choroidal Melanoma - Ocular melanoma often begins in the part of the uvea called the choroid, the vascular layer between the white part of the eye (sclera) and the Retina. (tnretina.com)
  • Ocular cancers, such as ocular melanoma and retinoblastoma, are particularly challenging to treat. (justia.com)
Tumors8
Cornea9
  • If directly assigning Summary Stage 2000 (SS2000), use the *Melanoma of the Cornea, Retina, Choroid, Ciliary Body, Eyeball, and Overlapping and Other Eye* chapter on page 262 of the [SS2000 on-line manual](http://seer.cancer.gov/tools/ssm/SSSM2000-122012.pdf#page=262). (cancer.gov)
  • At 8 months follow-up, the conjunctiva and the cornea were completely healed with resolution of all pigment and 20/20 visual acuity. (nih.gov)
  • Left eye is in more advanced stage, and the cancer spreads in intraepithelial and papillomatous fasion to both upper, lower bulbar conjunctiva, upper tarsal conjunctiva and penetrates into cornea. (tropical-ophthalmology.com)
  • A pinkish mass was found over the nasal conjunctiva and invading part of the cornea. (ekjo.org)
  • A) Photograph showing a juxta-limbal mass over the nasal conjunctiva and invading the cornea. (ekjo.org)
  • Slit-lamp biomicroscopy revealed a markedly elevated mass without pigmentation, measuring about 9×7 mm with well-defined edges, on the nasal section of the bulbar conjunctiva invading the nasal part of the cornea. (ekjo.org)
  • The most useful architectural patterns suggestive of conjunctival melanoma include (1) intraepithelial component showing pagetoid growth (2) radial extension of the intraepithelial component beyond the lateral edge of subepithelial component, (3) patchy or bandlike inflammation at the base of the lesion, (4) mitotic activity, (5) lack of maturation toward the base of the lesion, (6) invasion of the sclera or cornea. (surajeyeinstitute.org)
  • Moreover, ultraviolet radiation causes eye diseases such as cataract and inflammation of the cornea (photokeratitis) and conjunctiva (photoconjunctivitis). (123essaywriting.com)
  • Squamous cell carcinoma can occur not just on the skin, but on the conjunctiva and invade the cornea and inside of the eye, in some cases necessitating removal of the entire eye. (eyemedicalclinic.com)
Metastasis7
  • reported an isolated gastric metastasis from a conjunctival melanoma. (medscape.com)
  • Patients who die from ciliary body melanoma die because of distant metastasis rather than local spread. (medscape.com)
  • This is different from melanoma that spreads to the eye after it started somewhere else in the body, through a process called metastasis. (cancer.net)
  • Liver enzyme levels are indicated in any patient with uveal melanoma, because the liver is the most common site of choroidal melanoma metastasis. (medscape.com)
  • Variable Results for Uveal Melanoma-Specific Gene Expression Profile Prognostic Test in Choroidal Metastasis. (ucla.edu)
  • The most common malignancies include uveal and conjunctivitis melanoma, uveal metastasis, intraocular and conjunctiva lymphoma and conjunctiva carcinoma. (ophthalmologyconferences.com)
  • The symptoms of malignant melanoma of the nasal cavity and sinuses are concealed and complex, with high degrees of malignancy and metastasis and extremely poor prognosis. (sdu.edu.cn)
Carcinoma10
  • C690 Conjunctiva **Note 1:** This schema is based on the UICC chapter *Carcinoma of Conjunctiva,* pages 276-278. (cancer.gov)
  • Other types of common eyelid cancers include squamous carcinoma, sebaceous carcinoma and malignant melanoma. (wikipedia.org)
  • We describe our current approach to the surgical management of squamous cell carcinoma (intraepithelial or invasive), localized melanoma, and primary acquired melanosis of the conjunctiva. (nih.gov)
  • Our observations suggest that well-planned initial surgical management using this technique decreases the chance of tumor recurrence for conjunctival melanoma and squamous cell carcinoma. (nih.gov)
  • Invasive pigmented squamous cell carcinoma of conjunctiva. (tropical-ophthalmology.com)
  • 3 Irritative symptoms are frequent in seborrheic keratosis, and the swelling of these lesions can be mistaken for basal cell carcinoma or malignant melanoma. (ekjo.org)
  • Both conjunctival melanoma and squamous carcinoma have been associated with sun (ultraviolet UV-ray) exposure, so Dr. Finger says, "Think of Sunglasses as Sunblock for your Eyes. (eyecancercure.com)
  • In these families, members who inherit this faulty gene can develop uveal melanoma and/or other unusual cancers such as mesothelioma (a cancer of the lining of the lung), renal cell carcinoma (cancer of the kidney), or certain skin cancers. (retinaconsultantstexas.com)
  • Excessive solar radiation contributes to the abnormal growth of skin cells, which lead to the development of skin cancers such as melanoma, carcinoma, and others. (123essaywriting.com)
  • Additional malignancies considered in a patient on chronic immunosuppression include Kaposi's sarcoma, squamous cell carcinoma and amelanotic melanoma. (reviewofophthalmology.com)
Bulbar6
Tumor16
  • Melanoma is the most common type of eye tumor in adults. (medlineplus.gov)
  • The most common malignant primary intraocular tumor in adults is uveal melanoma. (wikipedia.org)
  • Melanomas (choroidal, ciliary body and uveal) - In the early stages there may be no symptoms (the person does not know there is a tumor until an ophthalmologist or optometrist looks into the eye with an ophthalmoscope during a routine test). (wikipedia.org)
  • Melanoma is a malignant tumor of melanocytes, which are the cells that make the pigment melanin and are derived from the neural crest. (cancer.gov)
  • The conjunctival melanoma was completely resected microsurgically in one piece without disrupting the tumor. (nih.gov)
  • Preliminary evidence suggests that combined therapeutic approaches, consisting of extensive tumor removal, cryotherapy, amniotic membrane allograft, and topical mitomyin C, can be effective in the management of diffuse conjunctival and corneal melanoma arising from primary acquired melanosis. (nih.gov)
  • Ciliary body melanoma is a rare tumor. (medscape.com)
  • Ciliary body melanoma is a subtype of uveal melanoma, the most common primary malignant tumor of the eye. (medscape.com)
  • They can be classified as anterior uveal melanomas when the tumor arises in the iris and as posterior uveal melanomas when it arises in either the choroid or the ciliary body. (medscape.com)
  • Eye melanoma begins when melanocytes change and grow out of control, forming a mass called a tumor. (cancer.net)
  • This guide is about primary eye melanoma, which means the tumor started in the eye. (cancer.net)
  • As the tumor enlarges, it may cause distortion of the pupil (iris melanoma), blurred vision (ciliary body melanoma), or markedly decreased visual acuity caused by secondary retinal detachment (choroidal melanoma). (cigna.com)
  • Retinoblastoma in children and uveal melanoma in adults represent two of the most common primary intraocular tumor s [ 1 , 2 ]. (omicsonline.org)
  • Cellular blue nevus is an uncommon pigmented tumor in the conjunctiva, where it generally appears as a deep, circumscribed, pigmented conjunctival mass. (jamanetwork.com)
  • That means that the cancer tumor started in the eye instead of somewhere else in the body and that melanoma is the most common form. (opticalmasters.com)
  • Physical examination found a 3.0- × 2.7-cm vascular friable tumor on his?left lower eyelid with surrounding erythema ectropion and injected conjunctiva (Fig 1). (researchhunt.com)
Cutaneous melanoma5
  • [ 3 ] Gastric metastases are frequently seen in cutaneous melanoma. (medscape.com)
  • Uveal melanomas differ significantly from cutaneous melanoma in incidence, prognostic factors, molecular characteristics, and treatment. (cancer.gov)
  • For the histological classification of cutaneous melanoma, the highest concordance was attained for Breslow thickness and presence of ulceration, while the agreement was poor for other histological features such as Clark level of invasion, presence of regression, and lymphocytic infiltration. (cancer.gov)
  • Additionally, UV light is associated with skin cancers including squamous cell carcinomas, basal cell carcinomas, and cutaneous melanoma. (eyemedicalclinic.com)
  • Global Burden of Cutaneous Melanoma in 2020 and Projections to 2040. (who.int)
Nevus10
  • Conjunctival melanomas may be associated with primary acquired melanosis (75%) or may arise from a preexisting nevus or de novo. (medscape.com)
  • Evidence indicates that approximately 20% to 25% of patients with conjunctival melanoma have a history or microscopic evidence of a benign conjunctival nevus. (medscape.com)
  • Although uveal melanomas may grow de novo, most develop from a preexisting melanocytic nevus. (medscape.com)
  • A small uveal melanoma cannot be distinguished from a nevus. (cigna.com)
  • We report a case of conjunctival blue nevus that clinically resembled primary acquired melanosis and gave rise to conjunctival melanoma. (jamanetwork.com)
  • Evidence indicates that approximately 20-25% of patients with conjunctival melanoma have a history or microscopic evidence of a benign conjunctival nevus. (medscape.com)
  • Malignant melanomas arising from nevi (they may arise from junctional and compound nevi) usually appear as a change (increasing nodularity, variegated pigmentation, bleeding, or inflammation) in known pigmented lesions of the conjunctiva, but it may be impossible to establish a clear clinical history of a preexisting history of nevus. (medscape.com)
  • Previously, compressed cells at the melanoma base were considered to be nevi, but reports now suggest that these flattened cells are, in fact, compressed melanoma cells and not nevus cells. (medscape.com)
  • We analyzed the expression of 84 miRNAs in 27 primary melanoma and 5 nevus formalin-fixed paraffin-embedded (FFPE) samples using the Human Cancer PathwayFinder miScript miRNA PCR Array. (bjbms.org)
  • Conjucitval melanoma, often arises from already existing pigmented lesions on the conjunctiva such as a conjuntival nevus or melanosis but can also develop spontaneously. (tnretina.com)
Squamous1
  • We have employed this technique on 109 patients with conjunctival squamous neoplasms and 137 patients with conjunctival melanoma, about 80 of which neoplasms were associated with primary acquired melanosis. (nih.gov)
Choroid7
  • The choroid layer is the most likely site of melanoma in the eye. (medlineplus.gov)
  • It usually remains hidden behind the iris diaphragm, growing undetected for longer periods of time than melanoma in the iris or choroid. (medscape.com)
  • More than 85% of uveal melanoma starts in the choroid. (cancer.net)
  • Melanoma of the uveal tract (iris, ciliary body, and choroid), though rare, is the most common primary intraocular malignancy in adults. (cigna.com)
  • Uveal melanomas can arise in the anterior (iris) or the posterior (ciliary body or choroid) uveal tract. (cigna.com)
  • 6 ] Most uveal tract melanomas originate in the choroid. (cigna.com)
  • Melanomas may also develop in the choroid layer of the eye, in the leptomeninges (pia or arachnoid mater), and in the nail beds. (msdmanuals.com)
Melanocytes5
  • Melanocytes are also present in normal skin and serve as the source cell for melanoma. (cancer.gov)
  • Primary ciliary body melanoma arises from melanocytes in the uveal tract. (medscape.com)
  • Melanoma is a type of cancer where cells called "melanocytes" grow uncontrollably. (opticalmasters.com)
  • Malignant melanoma arises from melanocytes in a pigmented area (eg, skin, mucous membranes, eyes, or central nervous system). (msdmanuals.com)
  • Melanoma can occur in any tissue that contains melanocytes. (bjbms.org)
Neoplasia2
  • However, the occurrence of this benign epithelial neoplasia on the conjunctiva is very rare. (ekjo.org)
  • There have been particularly substantial changes to the classification of conjunctival neoplasia and melanoma, based on the latest information from genetic and molecular studies. (iarc.fr)
Cases of conjunctival melanoma3
Risk of progression to melanoma1
  • 3. Which term is used for a group of lesions showing intraepithelial melanocytic proliferation with cytologic atypia, which is associated with a risk of progression to melanoma? (surajeyeinstitute.org)
Lesions of the conjunctiva2
  • Malignant melanomas arising from nevi (they may arise from junctional and compound nevi) usually appear as a change (increasing nodularity, variegated pigmentation, bleeding, or inflammation) in known pigmented lesions of the conjunctiva. (medscape.com)
  • Reference: Zembowicz A, Mandal RV, Choopong P. Melanocytic lesions of the conjunctiva. (surajeyeinstitute.org)
Lymphoma1
Atypia2
  • Explanation: Primary acquired melanosis (PAM) with atypia refers to a group of lesions showing intraepithelial melanocytic proliferation and/or increased cellularity and is associated with a risk of 36% -75% progression to melanoma. (surajeyeinstitute.org)
  • Though often benign, the flat, brown lesions on the conjuctiva are also the precursor to conjunctival melanoma, especially in cases of abnormal cellular structure (cellular atypia). (tnretina.com)
Personal history of melanoma2
Cells that produce melanin1
Corneal1
  • To illustrate a novel method of management for extensive conjunctival and corneal melanoma. (nih.gov)
Choroidal melanomas2
  • Ciliary body melanoma is more likely to spread outside the eye than iris and choroidal melanomas. (cancer.net)
  • Across the world, each eye cancer center has its own radiation methods to destroy choroidal melanomas. (eyecancercure.com)
Melanocytic2
Invasive melanoma1
  • Skin cancer is the most common malignancy diagnosed in the United States, and invasive melanoma represents about 1% of skin cancers but results in most deaths. (cancer.gov)
Adults6
  • however, melanoma is the most common cancer in young adults aged 25 to 29 years and the second most common cancer in those aged 15 to 29 years. (cancer.gov)
  • Melanoma occurs predominantly in adults, and more than 50% of the cases arise in apparently normal areas of the skin. (cancer.gov)
  • These are known as primary intraocular cancers with melanoma being the most common form in adults. (opticalmasters.com)
  • The most common eye cancer in adults is called uveal melanoma (or uveal melanoma). (eyes-road.eu)
  • Uveal melanoma is a rare malignant cancer of adults with less than 2,000 new cases diagnosed in the United States per year. (retinaconsultantstexas.com)
  • Uveal Melanoma is rare but is the most common form of eye cancer for adults. (tnretina.com)
Types of melanoma2
Posterior uveal2
Occur2
  • Although melanoma can occur anywhere, including on mucosal surfaces and the uvea, in women it occurs more commonly on the extremities, and in men it occurs most commonly on the trunk or head and neck. (cancer.gov)
  • Melanomas occur mainly on the skin but also on the mucosa of the oral, genital, and rectal regions and conjunctiva. (msdmanuals.com)
Nevi5
  • Theoretically, conjunctival melanoma may originate from primary acquired melanosis, preexisting nevi, or de novo lesions (without any histologic or clinical evidence of a preexisting lesion). (medscape.com)
  • However, some uncertainty surrounds the role of nevi in the histogenesis of malignant melanoma. (medscape.com)
  • In most cases, melanomas arise from pre-existing nevi (freckles or moles), which are benign in appearance and then transform into cancer. (retinaconsultantstexas.com)
  • The FFPE samples were obtained from the archives of the Municipal Clinical Emergency Hospital of Timisoara and included 10 cutaneous melanomas, 10 uveal melanomas, 7 mucosal melanomas, and 5 cutaneous nevi. (bjbms.org)
  • Among them, mir-9-5p, mir-203a-3p, mir-19a-3p, mir-27b-3p, and mir-218-5p showed altered expression in all three melanoma types vs. nevi. (bjbms.org)
Iris12
Intraepithelial1
  • Explanation: Presence of intraepithelial nests, cyst formation, and maturation with depth are not specific architectural clues for conjunctival melanoma, while the presence of pagetoid growth is a pattern suggestive of conjunctival melanoma. (surajeyeinstitute.org)
Mucosal melanoma4
  • The highest similarity in miRNA expression pattern was found between uveal and mucosal melanoma groups, i.e., 15 miRNAs had altered expression in both groups. (bjbms.org)
  • Review: mucosal melanoma of the head and neck[J]. Melanoma Res, 2011, 21(4): 257-266. (sdu.edu.cn)
  • Current management of mucosal melanoma of the head and neck[J]. J Surg Oncol, 2003, 83(2): 116-122. (sdu.edu.cn)
  • Head and neck mucosal melanoma: a review[J]. Am J Dermatopathol, 2014, 36(7): 578-587. (sdu.edu.cn)
Intraocular melanoma2
  • Careful examination by an experienced clinician remains the most important test to establish the presence of intraocular melanoma. (cigna.com)
  • Some medical history is favorable for intraocular melanoma. (eyes-road.eu)
Metastatic1
  • Blinded by the light: why the treatment of metastatic melanoma has created a new paradigm for the management of cancer[J]. Ther Adv Med Oncol, 2015, 7(2): 107-121. (sdu.edu.cn)
Orbit2
Uveal melanomas3
  • Uveal melanomas are the most common primary intraocular malignancies and the second most common type of primary malignant melanoma in the body. (medscape.com)
  • Three distinct cell types are recognized in uveal melanomas: spindle A, spindle B, and epithelioid. (medscape.com)
  • Most uveal melanomas are initially completely asymptomatic. (cigna.com)
Prognostic factors1
  • Methods Demographic data, known (published) prognostic factors, BRAF and KIT gene mutations, treatment strategies and outcomes were reviewed in 53 patients with pathologically confirmed conjunctival melanomas. (bmj.com)
Diagnosis7
  • 5 , 6 ] Agreement between pathologists in the histological diagnosis of melanomas and benign pigmented lesions has been found to be considerably variable. (cancer.gov)
  • One study found that there was discordance in the diagnosis of melanoma versus benign lesions in 37 of 140 cases examined by a panel of experienced dermatopathologists. (cancer.gov)
  • Small uveal lesions are observed for growth before making a diagnosis of melanoma. (cigna.com)
  • 5. Which architectural pattern is a clue to the diagnosis of conjunctival melanoma? (surajeyeinstitute.org)
  • To explore the clinical features, diagnosis, treatment outcomes, and prognosis of patients with malignant melanoma of the nasal cavity and paranasal sinuses. (sdu.edu.cn)
  • Early diagnosis and comprehensive treatment can significantly improve the survival rate of malignant melanoma. (sdu.edu.cn)
  • Advances in clinical diagnosis and treatment of sinonasal mucosal malignant melanoma[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2017, 31(2): 116-120. (sdu.edu.cn)
Diffuse1
  • A 40-year-old Caucasian woman presented with a large, diffuse conjunctival melanoma involving 6 clock hours of the limbus. (nih.gov)
Anterior uveal1
  • This podcast compares and contrasts resection versus plaque therapy for treatment of anterior uveal melanoma. (eyecancercure.com)
Cancer9
  • If directly assigning SS2000, use the *Conjunctiva* chapter on page 257 of the [SS2000 on-line manual](https://seer.cancer.gov/tools/ssm/ssm2000/SSSM2000-122012.pdf#page=257). (cancer.gov)
  • Melanoma of the eye is cancer that occurs in various parts of the eye. (medlineplus.gov)
  • Melanoma is a very aggressive type of cancer that can spread rapidly. (medlineplus.gov)
  • The outcome for melanoma of the eye depends on the size of the cancer when it is diagnosed. (medlineplus.gov)
  • This is the first page of Cancer.Net's Guide to Eye Melanoma. (cancer.net)
  • You can get melanoma cancer on your skin as well. (opticalmasters.com)
  • Findings have not been consistent in pinpointing something in the diet, genetics, or environmental risk factors to link uveal melanoma to the development of this cancer. (retinaconsultantstexas.com)
  • Overall, we identified several miRNAs with significantly altered expression in primary melanomas, including those reported for the first time in this type of cancer. (bjbms.org)
  • UV exposure increases the risk of melanoma (the most frequent cancer of the eyeball) drastically, which will normally have to be surgically removed. (boptom.com)
Patients9
  • Background/objective In patients with conjunctival melanomas, surgery is the first choice of treatment, but no standard adjuvant therapy has been established. (bmj.com)
  • Conclusions Adjuvant therapy and tumour thickness are significantly associated with RFS and T stage is a significant predictor of OS in Chinese patients with conjunctival melanomas. (bmj.com)
  • Long term follow-up of patients with conjunctival melanoma with systemic surveillance is necessary to detect recurrences and metastases. (duke.edu)
  • BACKGROUND Patients with uveal melanoma can be treated by a number of modalities. (bmj.com)
  • The reliability and validity of the three MOOD scores (total, vision, impact) were evaluated in 176 patients who had been treated for uveal melanoma (75 brachytherapy, 78 proton beam radiotherapy, 23 enucleation). (bmj.com)
  • Some patients do report floaters or decreased vision, but uveal melanoma typically does not cause pain. (retinaconsultantstexas.com)
  • Uveal melanoma is most common in patients who are Caucasian, have lightly colored blue or green eyes, and are over the age of 60. (retinaconsultantstexas.com)
  • A retrospective review was performed of 23 patients with malignant melanoma of the nasal cavity and paranasal sinuses treated between October 2007 and September 2018. (sdu.edu.cn)
  • Outcomes in patients with mucosal melanomas[J]. J Surg Oncol, 2013, 108(8): 516-520. (sdu.edu.cn)
Eyeball2
Lesion3
Excision2
  • The patient stated that the mass had recurred at the same site on the conjunctiva where a previous excision had been performed. (ekjo.org)
  • Photograph from another hospital showing a juxta-limbal mass over the nasal conjunctiva prior to mass excision. (ekjo.org)
Ciliary body melanomas2
  • Ciliary body melanomas are mostly found in Whites, particularly in those with light-colored irides. (medscape.com)
  • With respect to size, choroidal and ciliary body melanomas are generally 2mm - 12mm tall and 5mm - 18mm wide at the time that they are diagnosed. (retinaconsultantstexas.com)
Primary acquired1
  • Primary acquired melanosis is managed by alcohol epitheliectomy, removal of suspicious foci, quadrantic staging biopsies, and cryotherapy from the underside of the conjunctiva. (nih.gov)
Neoplasms1