RocaltrolVecticalPsoriasisEffects of calcitriolProduction of calcitriolConcert with parathyroid hormoneOintmentAbsorptionDoseBlood calcium levelsOsteoporosisReceptorCalcipotrieneDialysisIntestinalHypocalcemiaCholecalciferolActive form of vitaminAllergicDrugsSoriluxOrallyHypoparathyroidismCommonlyAnalogsClass of medications calledInteractionsCertain medicationsCombination medicationPrescription medicationsRenalIncreasesDoctor or pharmacistBoneTopicalPregnantParathyroid glandsDrugDosesHypercalcemiaLevelsDispensesPharmacistSymptomsForm of this medicationForms of this medicationKidneysInteractSupplementationTake this medicationBrandFamily of medications
Rocaltrol1
- Calcitriol is marketed under various trade names including Rocaltrol (Roche), Calcijex (Abbott) and Decostriol (Mibe, Jesalis). (drugbank.com)
Vectical2
- Each gram of VECTICAL Ointment contains 3 micrograms (mcg/g) of calcitriol. (nih.gov)
- Bu Vectical (Calcitriol) online from CanadianPharmacyOnline.com. (canadianpharmacyonline.com)
Psoriasis11
- Drug therapy for psoriasis may involve topical and systemic medications in conjunction with phototherapy and moisturizers. (medscape.com)
- Calcitriol is prescribed for: Treatment of hypocalcaemia - hypoparathyroidism, osteomalacia (adults), rickets (infants, children), renal osteodystrophy, chronic kidney disease Treatment of osteoporosis Prevention of corticosteroid-induced osteoporosis Calcitriol has been used in an ointment for the treatment of psoriasis, although the vitamin D analogue calcipotriol (calcipotriene) is more commonly used. (wikipedia.org)
- Calcitriol has also been given by mouth for the treatment of psoriasis and psoriatic arthritis. (wikipedia.org)
- Calcitriol topical is used to treat mild to moderate plaque psoriasis (a skin disease in which red, scaly patches form on some areas of the body) in adults and children 2 years of age and older. (medlineplus.gov)
- Apply calcitriol ointment to the areas of skin affected by plaque psoriasis. (medlineplus.gov)
- Certain medications like beta-blockers have been linked to psoriasis. (medicinenet.com)
- This medication is used to treat psoriasis. (insiderx.com)
- It contains an active ingredient, calcitriol (a vitamin D derivate) that inhibits and normalizes the unrestrained cell growth in psoriasis affected skin. (clickpharmacy.co.uk)
- It contains calcitriol as an active ingredient, and it has been scientifically tested and proven to be highly effective in treating psoriasis, helping people to achieve clear and fresh skin. (clickpharmacy.co.uk)
- Calcitriol is used to treat plaque psoriasis, which is a condition that results in the scaling and thickening of the skin due to excessive skin cell production. (clickpharmacy.co.uk)
- While there are multiple ways to treat the skin plaques in psoriasis, such as biologics , systemic medications, and light therapy , topical therapies are often used first . (healthline.com)
Effects of calcitriol2
- Many of the effects of calcitriol are mediated by its interaction with the calcitriol receptor, also called the vitamin D receptor or VDR. (wikipedia.org)
- In addition to its important role in calcium metabolism, other pharmacological effects of calcitriol have been studied in various conditions including cancer models. (drugbank.com)
Production of calcitriol2
- PTH also stimulates the production of calcitriol (see below). (wikipedia.org)
- Renal production of calcitriol is stimulated in response to PTH, low calcium and low phosphate 4 . (drugbank.com)
Concert with parathyroid hormone2
- Calcitriol acts in concert with parathyroid hormone (PTH) in all three of these roles. (wikipedia.org)
- Calcitriol plays a role in plasma calcium regulation in concert with parathyroid hormone (PTH) by enhancing absorption of dietary calcium and phosphate from the gastrointestinal tract, promoting renal tubular reabsorption of calcium in the kidneys, and stimulating the release of calcium stores from the skeletal system. (drugbank.com)
Ointment12
- Calcitriol comes as an ointment to apply to the skin. (medlineplus.gov)
- Apply calcitriol ointment at around the same times every day. (medlineplus.gov)
- Apply calcitriol ointment exactly as directed. (medlineplus.gov)
- In children 2 to 6 years of age, do not use more than one tube (100 gm) of calcitriol ointment per week. (medlineplus.gov)
- In adults and children 7 years of age and older, do not use more than two tubes (200 gm) of calcitriol ointment per week. (medlineplus.gov)
- Do not apply calcitriol ointment to healthy skin or anywhere on your face, eyes, lips, or vagina. (medlineplus.gov)
- Apply the ointment to the affected skin and gently rub the ointment into the skin until no medication is visible. (medlineplus.gov)
- Do not cover the skin where you applied calcitriol ointment with a bandage or dressing unless your doctor tells you that you should. (medlineplus.gov)
- Wash your hands well with soap and water after you apply calcitriol ointment. (medlineplus.gov)
- What is the difference between Silkis and tacalcitol and calcitriol ointment? (clickpharmacy.co.uk)
- Silkis ointment contains the active ingredient calcitriol, which is a type of medicine called a vitamin D analogue. (clickpharmacy.co.uk)
- Although no significant hypercalcemia (high blood calcium levels) was observed during the clinical studies with this ointment, there is some absorption of calcitriol by the skin. (clickpharmacy.co.uk)
Absorption4
- Calcitriol increases blood calcium levels ([Ca2+ ]) by: Promoting absorption of dietary calcium from the gastrointestinal tract. (wikipedia.org)
- Certain medications (bile acid sequestrants such as cholestyramine / colestipol , mineral oil , orlistat ) can decrease the absorption of vitamin D. Take your doses of these medications as far as possible from your doses of vitamin D (at least 2 hours apart, longer if possible). (webmd.com)
- If your normal drinking water is classified as 'hard water,' it may decrease the absorption of this medication and you should consider taking it with distilled water. (medbroadcast.com)
- These processes are controlled by two hormones: parathyroid hormone (affectionately called PTH) and calcitriol (affectionately known as vitamin D). Calcitriol acts to enhance calcium absorption into the body from the intestine, promote release of calcium from bone, and cause the kidney to avoid dumping calcium. (vin.com)
Dose12
- Regular blood tests are recommended after the medication is started and when the dose is changed. (wikipedia.org)
- If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. (webmd.com)
- Many things can affect the dose of medication that a person needs, such as the severity of the condition, other medical conditions and other medications. (medbroadcast.com)
- If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. (medbroadcast.com)
- Once the dose of each medication has been established, the combination tablet can be started. (medbroadcast.com)
- Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. (medbroadcast.com)
- The usual recommended dose of this medication is one tablet taken once a day, with or without food. (medbroadcast.com)
- The dose will depend on your response to the medication, and on your liver and kidney function. (medbroadcast.com)
- The duration of pharmacologic activity of a single dose of exogenous calcitriol is expected to be about 3 to 5 days Label . (drugbank.com)
- If you miss a dose of this medication, skip the missed dose and continue with your regular dosing schedule. (pharmachoice.com)
- Options for chronic treatment of hypoparathyroidism include calcitriol, recombinant human parathyroid hormone, and high-dose vitamin D (D 2 ). (medscape.com)
- [ 4 ] Currently available treatments for hypoparathyroidism include high-dose vitamin D (ergocalciferol, D 2 and cholecalciferol, D 3 ), the active metabolite 1,25-dihydroxvitamin D (calcitriol), recombinant human parathyroid hormone, in addition to calcium supplements. (medscape.com)
Blood calcium levels2
- This combination medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. (kaiserpermanente.org)
- If the kidneys do not produce enough calcitriol, blood calcium levels will drop, PTH levels will increase and more calcium will be removed from the bones. (tgh.org)
Osteoporosis2
- It can be given as a medication for the treatment of low blood calcium and hyperparathyroidism due to kidney disease, low blood calcium due to hypoparathyroidism, osteoporosis, osteomalacia, and familial hypophosphatemia, and can be taken by mouth or by injection into a vein. (wikipedia.org)
- Administered orally and intravenously, calcitriol is commonly used as a medication in the treatment of secondary hyperparathyroidism and resultant metabolic bone disease, hypocalcemia in patients undergoing chronic renal dialysis, and osteoporosis. (drugbank.com)
Receptor4
- For instance, the unbound inactive form of the calcitriol receptor in intestinal epithelial cells resides in the cytoplasm. (wikipedia.org)
- Finally, a genetic absence of the receptor for calcitriol results in deficient calcification. (medscape.com)
- Olmesartan belongs to the class of medications called angiotensin II receptor blockers and helps to lower blood pressure by blocking the action of a chemical ( angiotensin II) that causes blood vessels to constrict or tighten, thereby relaxing blood vessels. (medbroadcast.com)
- Calcitriol is a ligand for the vitamin D nuclear receptor, which is expressed in, but not limited to, gastrointestinal (GI) tissues, bones, and kidneys 1 . (drugbank.com)
Calcipotriene1
- Calcitriol is a topical vitamin D analog similar to calcipotriene but seems to be less irritating in sensitive areas of skin. (medscape.com)
Dialysis2
- Calcitriol is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. (drugbank.com)
- The patient has chronic kidney disease diagnosed in 1996 and is in dialysis 3 times a week ever since, besides hepatitis C virus and hypertension treated with medication. (bvsalud.org)
Intestinal6
- apalutamide will decrease the level or effect of calcitriol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- clarithromycin will increase the level or effect of calcitriol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- enzalutamide will decrease the level or effect of calcitriol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- idelalisib will increase the level or effect of calcitriol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- indinavir will increase the level or effect of calcitriol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. (medscape.com)
- As an active form of vitamin D 3 , calcitriol elevates the plasma levels of calcium by stimulating intestinal calcium uptake, increasing reabsorption of calcium by the kidneys, and possibly increasing the release of calcium from skeletal stores. (drugbank.com)
Hypocalcemia3
- Compare renal function, hypercalcemia, and hypocalcemia in patients with hypoparathyroidism treated chronically with either D 2 (D2 group) or calcitriol. (medscape.com)
- We found less morbidity from hypocalcemia in hypoparathyroid patients treated chronically with D 2 compared with calcitriol and found no difference in renal function or morbidity from hypercalcemia. (medscape.com)
- In this retrospective study, our goal was to compare renal function and incidents of hypercalcemia and hypocalcemia requiring medical treatment in patients with hypoparathyroidism treated chronically with D 2 (D2 group) vs calcitriol. (medscape.com)
Cholecalciferol2
- Compared to other vitamin D compounds in clinical use (cholecalciferol, ergocalciferol), calcitriol has a higher risk of inducing hypercalcemia. (wikipedia.org)
- This is a combination medication that contains alendronate and cholecalciferol. (medbroadcast.com)
Active form of vitamin2
- Calcitriol is the active form of vitamin D, normally made in the kidney. (wikipedia.org)
- Calcitriol was identified as the active form of vitamin D in 1971 and the drug was approved for medical use in the United States in 1978. (wikipedia.org)
Allergic2
- tell your doctor and pharmacist if you are allergic to calcitriol, any other medications, or any of the ingredients in calcitriol topical. (medlineplus.gov)
- are allergic to voriconazole or any ingredients of the medication (It is not known if people who are allergic to other 'azole' antifungal medications [e.g., ketoconazole, fluconazole, and itraconazole] will also be allergic to voriconazole. (pharmasave.com)
Drugs2
- Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. (medscape.com)
- The following drugs and medications are in some way related to, or used in the treatment of Gout. (remedymarket.com)
Sorilux1
- Sorilux is a newer foam version of this medication. (medscape.com)
Orally1
- If the kidneys are not producing adequate amounts of calcitriol, synthetic calcitriol can be taken orally or injected, and calcium supplements may be considered. (tgh.org)
Hypoparathyroidism3
- Vitamin D is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism , pseudohypoparathyroidism, familial hypophosphatemia ). (webmd.com)
- Calcitriol is the drug used most commonly in the United States for chronic hypoparathyroidism now, with only ~6% treated with D 2 [ 3 ] and increasing numbers of patients on human recombinant parathyroid hormone. (medscape.com)
- However, we are aware of no reports comparing treatment outcome with D 2 vs calcitriol for hypoparathyroidism. (medscape.com)
Commonly2
- In 2020, it was the 277th most commonly prescribed medication in the United States, with more than 1 million prescriptions. (wikipedia.org)
- Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D 3 , 1,25-dihydroxyvitamin D 3 . (drugbank.com)
Analogs2
- Research on the noncalcemic actions of calcitriol and other VDR-ligand analogs and their possible therapeutic applications has been reviewed. (wikipedia.org)
- Calcitriol is in a class of medications called vitamin D analogs. (medlineplus.gov)
Class of medications called1
- Hydrochlorothiazide belongs to the class of medications called diuretics or 'water pills' and helps control blood pressure by getting rid of excess salt and water. (medbroadcast.com)
Interactions2
- Essential nutrients interactions with medications pose major problems in treatment plans and may deplete nutrients in the body. (nutriiq.ca)
- In this article, we hope to give a hand to our colleagues and shed some light on possible supplement-medication interactions as essential nutrients can interact with certain medications, and some medications can have an adverse effect on essential nutrient levels. (nutriiq.ca)
Certain medications4
- It may also be used in certain patients to make sure they are getting enough calcium (including women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone). (kaiserpermanente.org)
- Inside Rx cannot be used with any insurance benefit, copay assistance programs, or by persons covered by state-funded or federal-funded programs such as Medicare, Medicaid, or Tricare for purchases of certain medications, even if processed outside the benefit as an uninsured (cash-paying) patient. (insiderx.com)
- Interaction of essential nutrients taken with certain medications is discussed below. (nutriiq.ca)
- Common triggers include trauma, infection, and certain medications. (msdmanuals.com)
Combination medication4
- This combination medication is used to treat mild to moderate high blood pressure for people who require treatment with both olmesartan and hydrochlorothiazide. (medbroadcast.com)
- This combination medication is used to make dosing more convenient for people who are already taking both of these medications (olmesartan and hydrochlorothiazide) separately. (medbroadcast.com)
- This combination medication is prescribed when your doctor feels it is appropriate for you to be taking both medications. (medbroadcast.com)
- You should already be taking each medication individually before starting this combination medication. (medbroadcast.com)
Prescription medications8
- on use of prescription medications during a one-month period prior to the survey date. (cdc.gov)
- In general, non-prescription medications that were reported in the prescription drug section of the household adult questionnaire were moved to the non-prescription medications section (the expanded non-prescription pain relief medications section to be described later), but those medications reported on the household youth questionnaire were deleted since a non-prescription medications section was not included on the youth questionnaire. (cdc.gov)
- On the adult questionnaire, aspirin was moved to the non-prescription medications sections unless the strength or brand name reported was only available by prescription (e.g. (cdc.gov)
- However, for five prescription medications a generic name or code did not exist. (cdc.gov)
- Save up to 80% on brand & generic prescription medications. (insiderx.com)
- Canadian Pharmacy Online dispenses prescription medications from Canada through our affiliated Canadian pharmacies that are duly licensed in the province of British Columbia and Manitoba. (canadianpharmacyonline.com)
- EasyDrugCard.com is available for all pet owners to get discounts on prescription medications at retail pharmacies across the U.S. Our program is free to all users. (easydrugcard.com)
- Instead of purchasing prescription medications at the vet's office, our members can now take advantage of savings offered through our free EasyDrugCard discount program for prescription pet medications filled at 65,000+ pharmacies. (easydrugcard.com)
Renal2
- To diagnose renal osteodystrophy, a physician may order bloodwork to measure the levels of calcium, phosphorus, PTH and calcitriol in the blood. (tgh.org)
- A tailored treatment plan, which may include dietary changes, supplements, regular exercise and medication, can boost the body's ability to repair bones damaged by renal osteodystrophy. (tgh.org)
Increases1
- Calcitriol increases blood calcium (Ca2+) mainly by increasing the uptake of calcium from the intestines. (wikipedia.org)
Doctor or pharmacist1
- Ask your doctor or pharmacist how long you should wait between doses and for help finding a dosing schedule that will work with all your medications. (webmd.com)
Bone2
- Calvit plus is a combination of calcitriol, elemental calcium & ele zn which is used as a bone joint. (clickindia.com)
- Calcitriol is a medication used to treat low-level calcium and bone-related disease. (shubham.co.in)
Topical4
- Tazarotene, although topical, is a category X medication. (medscape.com)
- If you are breastfeeding while using calcitriol topical, do not apply it directly to the nipple and areola (the colored area around each nipple). (medlineplus.gov)
- Calcitriol topical may cause side effects. (medlineplus.gov)
- Like oral medications, topical treatments come with risks. (healthline.com)
Pregnant1
- If you become pregnant while using calcitriol topcial, call your doctor. (medlineplus.gov)
Parathyroid glands3
- Overactive parathyroid glands may be controlled with dietary changes or medication. (tgh.org)
- Calcitriol shuts off PTH production in the parathyroid glands. (vin.com)
- Over time, the parathyroid glands become hyperplastic and less susceptible to treatment with calcium and calcitriol, producing a continuous secret ion of PTH and result ing secondar y hyperparathyroidism 3 . (bvsalud.org)
Drug4
- Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. (medbroadcast.com)
- Avoid or substitute another drug for these medications when possible. (medscape.com)
- Use our drug pricing tool to find the best price for your pet medications at a pharmacy near you. (easydrugcard.com)
- [ 5 ] In the United States, only D 2 (not D 3 ) is available as a Food and Drug Administration-approved medication, although comparable doses of D 3 (50,000 IU tablets) are available over the counter in some pharmacies and from Internet sources. (medscape.com)
Doses2
- Your doctor may need to change the doses of your medications or monitor you carefully for side effects. (medlineplus.gov)
- A side effect is an unwanted response to a medication when it is taken in normal doses. (pharmachoice.com)
Hypercalcemia1
- There were no differences between D2 and calcitriol groups in hospitalizations or ED visits for hypercalcemia, serum creatinine or calcium, or kidney stones. (medscape.com)
Levels9
- High calcitriol levels may also be seen in human disease states in patients not on supplementation. (wikipedia.org)
- In someone with hypercalcaemia and high calcitriol levels, low intact parathyroid hormone levels are usually present. (wikipedia.org)
- The major conditions with hypercalcaemia due to elevated calcitriol levels are lymphoma, tuberculosis and sarcoidosis where excess production occurs due to ectopic 25(OH)D-1-hydroxylase (CYP27B1) expressed in macrophages. (wikipedia.org)
- Vitamin D influences these levels after its dihydroxylation into calcitriol. (medscape.com)
- Calcitriol levels may be normal in patients with rickets, suggesting that it is not the only active form of the vitamin. (medscape.com)
- Vitamin D influences these levels after its dihydroxylation into calcitriol (at the 25 position in the liver and the 1 position in the kidney). (medscape.com)
- Indeed, it is in anticipation to such requirements that maternal calcitriol levels increase during pregnancy. (who.int)
- While the total calcitriol levels double in the first trimester, free calcitriol levels do not increase until the third trimester, and remain so into lactation [2, 4] . (who.int)
- The changes in calcitriol levels led to the description of pregnancy as a state of absorptive hypercalciuria [1 , 2 ]. (who.int)
Dispenses1
- CanadaPharmacy.com dispenses medications through our affiliated Canadian dispensing pharmacy which is licensed in the province of Manitoba, Canada. (canadapharmacy.com)
Pharmacist2
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. (medlineplus.gov)
- Ask your pharmacist how to dispose of medications that are no longer needed or have expired. (medbroadcast.com)
Symptoms1
- Do not give this medication to anyone else, even if they have the same symptoms as you do. (medbroadcast.com)
Form of this medication1
- If you are taking the chewable form of this medication, chew thoroughly before swallowing. (kaiserpermanente.org)
Forms of this medication2
- As well, some forms of this medication may not be used for all of the conditions discussed here. (medbroadcast.com)
- Voriconazole tablets and oral suspension, as well as the injectable forms of this medication, should be stored at room temperature. (pharmasave.com)
Kidneys1
- Healthy kidneys also produce calcitriol, a form of vitamin D, to help the body absorb dietary calcium into the blood and the bones. (tgh.org)
Interact1
- Many other medications may also interact with calcitriol, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
Supplementation1
- However, supplementation is regarded as a bio-hack en mass. (nutriiq.ca)
Take this medication7
- You do not need to take this medication with water. (webmd.com)
- Take this medication regularly to get the most benefit from it. (webmd.com)
- Take this medication by mouth with food. (kaiserpermanente.org)
- It can be harmful for people to take this medication if their doctor has not prescribed it. (medbroadcast.com)
- Do not take this medication at bedtime or before getting up in the morning. (medbroadcast.com)
- It is important to take this medication exactly as prescribed by your doctor. (medbroadcast.com)
- Who should NOT take this medication? (medbroadcast.com)
Brand2
- This medication may be available under multiple brand names and/or in several different forms. (medbroadcast.com)
- Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. (medbroadcast.com)
Family of medications1
- Voriconazole belongs to the family of medications called antifungals . (pharmasave.com)