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  • Development and validation of a high-performance liquid chromatographic analytical procedure for simultaneously determining metronidazole and ofloxacin in a synthetic mixture is described in this paper. (journals.cz)
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  • The calibration curves were linear in the concentration range of 12.5 to 100.0 µg/ml for metronidazole and ofloxacin, and the regression coefficients were more than 0.999. (journals.cz)
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  • We concluded that ofloxacin can be used as a drug of choice for typhoid fever, in those adult patients who are infected with S. typhi resistant to chloramphenicol, ampicillin and cotrimoxazole. (aku.edu)
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  • Mutations in drug resistance determining regions for dapsone , rifampicin and ofloxacin , of M. leprae genome in DNA extracted from skin biopsies of 136 leprosy patients ( treatment -naive=67, with persistent skin lesions=35, with recurrence =34) were analyzed by polymerase chain reaction followed by Sanger sequencing. (bvsalud.org)
  • Within this subset of 23 cases, resistance to ofloxacin was observed in 17 individuals (12.5%), while resistance to both dapsone and rifampicin was detected in 3 patients each (2.2% for both). (bvsalud.org)
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