Mediates polymerase factor. Medical search. Frequent questions

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death. (wikipedia.org)
CTCF binding to promoter sites bidirectionally regulates gene transcription and depends on activation of poly-ADP-ribose polymerase 1 (PARP1). (jneurosci.org)
Several main apoptotic indicators were found in GS-002-treated cells, such as the cleaved forms of caspase-3, caspase-9, and poly(ADP-ribose) polymerase (PARP). (hindawi.com)
ADP-ribosylation is a reversible posttranslational modification mediated by poly-ADP-ribose polymerase (PARP). (elsevierpure.com)

Integrator and protein phosphatase 2A (PP2A) form a complex that dephosphorylates paused RNA polymerase II (Pol II), cleaves the nascent RNA, and terminates transcription. (rcsb.org)
Hamdan SM, Marintcheva B, Cook T, Lee SJ, Tabor S, and Richardson CC. A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor. (edu.sa)
For example, transcript elongation factor TFIIS is highly conserved among eukaryotes, and yet the TFIIS protein from Saccharomyces cerevisiae cannot function with mammalian RNA polymerase II and vice versa. (embl.de)
Yeast domain II alone is able to bind yeast RNA polymerase II with the same affinity as the full-length TFIIS protein, and this domain was expected to confer the species selectivity. (embl.de)
BRDs can act as scaffolds that enable the recruitment of large protein complexes or they can act as transcription factors themselves. (frontiersin.org)
WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif. (embl.de)
In yeast, this bridging involves interactions between the WW domains in the splicing factor PRP40 and a proline-rich domain in the branchpoint binding protein, BBP. (embl.de)
Viral DNA synthesis involves a DNA repair enzyme, the uracil-DNA glycosylase D4 linked to the structural protein A20 forming the processivity factor, which in turn binds to E9 forming the complex required for processive DNA synthesis. (biorxiv.org)
Protein expression of tumor necrosis factor receptor type Ⅰ (TNFR1) was analyzed with Western blotting. (jcimjournal.com)
GS-002 also induced endoplasmic reticular (ER) stress as evidenced by increases in ER stress-responsive proteins including glucose-regulated protein 78 (GRP78), growth arrest- and DNA damage-inducible gene 153 (GADD153), phosphorylated eukaryotic initiation factor 2 α (eIF2 α ), phosphorylated protein endoplasmic-reticular-resident kinase (PERK), and ATF-3. (hindawi.com)
The induction of ATF-3 expression was mediated by mitogen-activated protein kinase (MAPK) signaling pathways in GS-002-treated cells. (hindawi.com)
A model is proposed where the relative levels of active antagonist (RsbV1) and switch-protein anti-sigma factor (RsbW) control the availability of σ 66 and subsequently act as a molecular 'throttle' for Chlamydia growth and development. (plos.org)
The cytoprotective and anti-inflammatory activity of APC is mediated through binding to its receptor, endothelial cell protein C receptor (EPCR). (biomedcentral.com)
In yeast and humans, nucleotide excision repair (NER) of ultraviolet (UV)- damaged DNA requires a large number of highly conserved protein factors, which include the multisubunit RNA polymerase II transcription factor TFIIH. (utmb.edu)
Transfections were used to determine the role of NF-κB,CCAAT/enhancer binding protein (C/EBPβ), and MAPK on cytokine-mediated CCL3 promoter activity. (shu.ac.uk)
The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. (taq-polymerase-dna.com)
Protein conformation is critically linked to function and often controlled by interactions with regulatory factors. (cipsm.de)
Preexisting antivector immunity can severely compromise the ability of Salmonella enterica serovar Typhimurium live vaccines to induce protective CD8 T-cell frequencies after type III secretion system-mediated heterologous protein translocation in orally immunized mice. (cipsm.de)

The morphologic, molecular, and clinical data suggest that erythema induratum and nodular vasculitis represent a common inflammatory pathway: an immune-mediated hypersensitivity reaction to endogenous or exogenous antigens, one such antigen being M tuberculosis . (medscape.com)
The etiology of erythema induratum remains poorly understood, although there is consensus that the erythema induratum/nodular vasculitis complex is a multifactorial, immune-mediated hypersensitivity reaction. (medscape.com)
Natural killer cells are cytolytic lymphocytes belonging to the innate immune system and are involved in anti-viral and anti-tumor responses ( 1 ) and are recognized as major players in immune-mediated anti-tumor therapies ( 2 ). (frontiersin.org)
Brain infection is thought to occur by means of direct neuronal transmission of the virus from a peripheral site to the brain via the trigeminal or olfactory nerve and indirect immune-mediated processes inducing neuroinflammation. (medscape.com)
The etiology of lung transplantation-related pathology is almost always immune-mediated. (medscape.com)

The dissociable sigma (σ) factor subunit directs the RNAP to different sets of genes to allow their expression in response to various cellular needs. (nih.gov)
Yeast RNA polymerase II subunit RPB9. (embl.de)
The RPB9 subunit of RNA polymerase II regulates transcription elongation activity and is required for the action of the transcription elongation factor, TFIIS. (embl.de)
The four-subunit negative elongation factor (NELF) complex mediates RNA polymerase II (Pol II) pausing at promoter-proximal regions. (bvsalud.org)

Polymerase chain reaction (PCR) assays and sequencing was used to determine the presence of β-lactamase encoding genes (bla) including bla NDM-1 and plasmid-mediated quinolone and aminoglycoside resistance determinants. (who.int)
Multidrug-resistant Shigella sonnei carrying plasmid-mediated mcr-1 gene in China. (cdc.gov)
In November 2015, a report from China first described plasmid-mediated colistin-resistance caused by the mcr-1 gene. (cdc.gov)

FLD localizes to actively transcribed genes, where it colocalizes with elongating RNA polymerase II phosphorylated at the Ser2 or Ser5 sites. (nature.com)
Genome-wide transcription analyses suggest that FLD-mediated H3K4me1 removal negatively regulates the transcription of genes with high levels of antisense transcription. (nature.com)
To isolate possible mechanisms underlying these structural and functional changes, we used whole-genome RNA sequencing and found prominent dopamine-induced enrichment of genes containing the CCCTC-binding factor (CTCF) motif, suggesting involvement of chromatin restructuring in the nucleus. (jneurosci.org)
The osteoclast differentiation-related genes and proteins were investigated by real-time polymerase chain reaction and immunoblotting. (e-jbm.org)
Human transcription factor IIIC (hTFIIIC) is a multisubunit complex that mediates transcription of class III genes through direct recognition of promoters (for tRNA and virus-associated RNA genes) or promoter-TFIIIA complexes (for the 5S RNA gene) and subsequent recruitment of TFIIIB and RNA polymerase III. (embl.de)
We mapped all estrogen receptor and RNA polymerase II binding sites on a genome-wide scale, identifying the authentic cis binding sites and target genes, in breast cancer cells. (nature.com)
Combining this unique resource with gene expression data demonstrates distinct temporal mechanisms of estrogen-mediated gene regulation, particularly in the case of estrogen-suppressed genes. (nature.com)
CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes. (iium.edu.my)
These cells may be activated by a wide range of stimuli, such as immunological, inflammatory or bacterial components, to express a diversity of "early immediate genes", including Tissue Factor (TF) and Tumour Necrosis Factor a (TNFa) (1-3). (thermofisher.com)

Further analysis of two overlapping deficiency lines and mutant alleles led to identification of genetic interactions between the CDK8-CycC pair and the components of the Decapentaplegic (Dpp, the Drosophila homolog of TGFβ, or Transforming Growth Factor-β) signaling pathway. (sdbonline.org)
It was observed that CDK8-CycC positively regulates transcription activated by Mad (Mothers against dpp) , the primary transcription factor downstream of the Dpp/TGFβ signaling pathway . (sdbonline.org)
It will not bind calcium, which is required for initiation of the clotting cascade through the extrinsic and Tissue Factor dependent pathway. (thermofisher.com)
Conventional therapeutic approaches for tumor angiogenesis, which are primarily focused on the inhibition of active angiogenesis to starve cancerous cells, target the vascular endothelial growth factor signaling pathway. (biomedcentral.com)
PCNs induced PAR-1/PAR-3 heterodimerization through EPCR occupation and PAR-1 activation, which resulted in Gα13-RhoA-mediated-Tie2 activation and stabilized vascular tight junctions via the Akt-FoxO3a signaling pathway. (biomedcentral.com)
Discussion at the Vancouver meeting spanned several areas of research, including signaling pathway activation of EMT and the transcription factors and gene targets involved. (rupress.org)
We found that (1) arsenite stimulated TF synthesis and activated the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway in HASMCs, (2) sulforaphane, an Nrf2 activator, also stimulated TF synthesis in HASMCs, and (3) arsenite-induced upregulation of TF synthesis was prevented by Nrf2 knockdown in HASMCs. (go.jp)
The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. (taq-polymerase-dna.com)

The multisubunit RNA polymerase (RNAP) is the central enzyme responsible for RNA synthesis in bacteria. (nih.gov)

TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. (nih.gov)
TFIIA in a complex with TBP mediates transcriptional activity. (nih.gov)

Given the important role of both cytokine-mediated inflammatory microenvironment and cytolytic NK cell activities in immune-oncology therapies, our findings present a compelling argument for further clinical investigation. (frontiersin.org)
Pretreatment of macrophages with an antagonist of CCR1, the primary receptor for CCL3 and CCL4, blocked cytokine-mediated migration. (shu.ac.uk)

Quantitative reverse transcription polymerase chain reaction and immunohistochemistry were used to measure CCL3 expression in NP cells. (shu.ac.uk)
The medium fragment encodes the envelope glycoproteins G1 and G2, regions of which are conserved among Hantaviruses, allowing the identification of new strains by reverse transcriptase polymerase chain reaction (RT-PCR) and immunohistochemistry. (medscape.com)

Expression of tumor necrosis factor-α (TNF-α) mRNA was analyzed with real-time fluorescent quantitative polymerase chain reaction. (jcimjournal.com)
The serum levels of miR-26 were determined by quantitative polymerase chain reaction (qPCR). (amegroups.org)

Because erythema induratum involves vasculitis, it is likely that endothelial antigens are a target of cell-mediated cytotoxic processes occurring in erythema induratum. (medscape.com)
In contrast, knockdown of BRD4 but not of BRD2 impairs NK cell cytolytic responses, suggesting BRD4 as critical regulator of NK cell mediated tumor cell elimination. (frontiersin.org)
The resulting inflammatory response leads to hepatitis and necrosis and appears to be T-cell mediated. (medscape.com)
The disease usually occurs in patients with impaired cell-mediated immunity, particularly patients with HIV infection. (msdmanuals.com)
Progressive multifocal leukoencephalopathy is suspected in patients with unexplained progressive brain dysfunction, particularly in those with depressed cell-mediated immunity. (msdmanuals.com)

Here, we report that transcription factor NFAT binds to and is ADP-ribosylated by PARP-1 in an activation-dependent manner. (elsevierpure.com)
Functionally, NFAT-mediated interleukin-2 (IL-2) expression was reduced in T cells upon genetic ablation or pharmacological inhibition of PARP-1. (elsevierpure.com)
Together, these results demonstrate that ADP-ribosylation mediated by PARP-1 provides a molecular switch to positively regulate NFAT-dependent cytokine gene transcription. (elsevierpure.com)

Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion. (mayo.edu)

This finding suggests a role for this σ 54 in gene regulation that extends beyond its known function as an RNAP gene specificity factor. (nih.gov)
Our findings propose epigenetic regulation of chromatin landscape as a critical factor in the rapid astrocyte response to dopamine. (jneurosci.org)
To investigate tumor necrosis factor α (TNF α) and interleukin-1β (IL-1 β) regulation of CCL3 expression in nucleus pulposus (NP) cells and in macrophage migration. (shu.ac.uk)

It binds sites with single-strand breaks through its N-terminal zinc fingers and will recruit XRCC1, DNA ligase III, DNA polymerase beta, and a kinase to the nick. (wikipedia.org)
Integrator binds Pol II and the pausing factors DSIF and NELF to exclude binding of the elongation factors SPT6 and PAF1 complex. (rcsb.org)

Target enzymes include DNA ligase III (LigIII), DNA polymerase beta (polβ), and scaffolding proteins such as X-ray cross-complementing gene 1 (XRCC1). (wikipedia.org)
Two of these WW domains, in the proteins FBP11 and FBP21, are strikingly similar to those found in the yeast splicing factor PRP40. (embl.de)
By several independent criteria, including co-purification, immunoprecipitation, and gel filtration of homogeneous proteins, we show that the damage recognition factor Rad14 exists in a ternary complex with the Rad1-Rad10 nuclease. (utmb.edu)

Domain I also interacts with the transcriptionally active RNA polymerase II holoenzyme and therefore, may have a function unrelated to the previously described transcription elongation activity of TFIIS. (embl.de)
We present the strategy for the production of the VACV DNA polymerase holoenzyme composed of the E9 polymerase associated with its co-factor, the A20-D4 heterodimer, which led to the 3.8 Å cryo-electron microscopy (cryo-EM) structure of the DNA-free form of the holoenzyme. (biorxiv.org)
As for the MPXV holoenzyme, a contact between E9 and D4 is mediated by a cluster of hydrophobic residues. (biorxiv.org)
Here we present the first structure of the vaccinia virus polymerase holoenzyme E9-A20-D4 at 3.8 Å obtained by cryo-electron microscopy. (biorxiv.org)

The first mechanism involves killing mediated by cytotoxic molecules ( e.g. perforin and granzymes) that are stored in secretory granules of lysosomal origin ( 7 ). (frontiersin.org)

They are differentiated and activation from monocytes/macrophages in the presence of macrophage colony-stimulating factor and receptor activator of nuclear factor-κB ligand (RANKL). (e-jbm.org)
Osteoclast formation is controlled by 2 cytokines, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL), which are secreted by osteoblasts/activated T cells. (e-jbm.org)
Figure 2: Estrogen-mediated transcript changes and correlation with estrogen receptor binding. (nature.com)
Figure 4: Identification of enriched motifs within the estrogen receptor binding sites and validation of transcription factor binding. (nature.com)
Figure 5: Involvement of cooperating transcription factors at estrogen receptor binding sites. (nature.com)

More specifically, erythema induratum is thought to result from an immune-complex-mediated (type III hypersensitivity) vascular injury due to bacterial antigens. (medscape.com)
Tissue factor (TF) is the initiator of the coagulation cascade, constitutively expressed in subendothelial cells such as vascular smooth muscle cells and initiating rapid coagulation when the vascular vessel is damaged. (go.jp)
The lymphoblasts and the macrophages recruited to pulmonary tissue by the high viral burden may provoke a lymphokine-mediated activation of vascular endothelium, thereby increasing pulmonary capillary permeability. (medscape.com)

Results of the enzyme-linked immunosorbent assay-based interferon-gamma release assay blood test for tuberculosis are often positive in patients with erythema induratum, again suggesting that erythema induratum is a hypersensitivity reaction to a systemic infection, and that erythema induratum has features of both type III (immune-complex-mediated) and type IV (delayed-type) hypersensitivity reactions. (medscape.com)
[ 3 ] Infection with M tuberculosis is considered to be an etiologic factor for erythema induratum that is associated with tuberculosis (Bazin disease), and, based on published reports, latent or active TB infection is the most common reported identifiable cause of erythema induratum. (medscape.com)
The major risk factors include chronic hepatitis B virus (HBV) infection, chronic hepatitis C virus (HCV) infection, environmental carcinogens such as aflatoxin B1 (AFB1), alcoholic cirrhosis, and inherited genetic disorder such as hemochromatosis, Wilson's disease, and tyrosinemia. (hindawi.com)
ABSTRACT The objectives of this study were to document the background prevalence and incidence of HCV infection among HCWs in Ain Shams University Hospitals in Cairo and analyse the risk factors for HCV infection. (who.int)
RÉSUMÉ Les objectifs de la présente étude étaient de documenter la prévalence et l'incidence de fond de l'infection par le virus de l'hépatite C chez les agents de santé de l'hôpital universitaire Ain Shams du Caire et d'analyser les facteurs de risque de contracter une infection par le virus de l'hépatite C. Une enquête transversale a été menée en 2008 auprès de 1770 agents de santé. (who.int)

TFIIS is a transcription elongation factor that consists of three domains. (embl.de)
We have previously solved the structures of domains II and III, which stimulate arrested polymerase II elongation complexes in order to resume transcription. (embl.de)
HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation. (iium.edu.my)
Here we show that negative elongation factor (NELF), an RNA polymerase II (Pol II) pausing factor, cooperates with TCF1 in T cell responses to cancer. (bvsalud.org)

C1QBP promotes the catabolism of hypoxanthine and elevates the apoptosis of RCC cells by modulating XDH-mediated ROS generation. (medsci.org)
Hepatocyte apoptosis was determined by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling staining. (jcimjournal.com)
Activating transcription factor-(ATF-) 3, a stress-inducible transcription factor, is rapidly upregulated under various stress conditions and plays an important role in inducing cancer cell apoptosis. (hindawi.com)
These results suggest that the induction of apoptosis by the propolis derivative, GS-002, is partially mediated through ER stress and ATF-3-dependent pathways, and GS-002 has the potential for development as an antitumor drug. (hindawi.com)

Figure 6: The role of NRIP1 in mediating gene repression. (nature.com)

Different activator ATPases couple diverse environmental cues to the σ 54 -RNAP to mediate adaptive changes in gene expression. (nih.gov)
These results indicate that astrocyte response to elevated dopamine involves PARP1-mediated CTCF genomic restructuring and concerted expression of gene networks. (jneurosci.org)
EFV reduced RANKL-mediated osteoclast formation and activation by inhibiting expression of nuclear factor of activated T cells 1, a key factor of osteoclastogenesis. (e-jbm.org)
The regulatory relationship between the expression levels of inflammatory factors, including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and IL-1β, and the expression levels of miR-26 in the supernatant of each group of cells was determined by qPCR. (amegroups.org)
In ADSCs transfected with miR-26, the miR-26 expression in the cell supernatant was negatively regulated by the expression of inflammatory factors, TNF-α, IL-6, and IL-1β, in the cell supernatant. (amegroups.org)

Moreover, NK cells are poised to release cytokines such as IFN- γ , TNF-α and growth factors that can initiate inflammatory responses mediated by both the innate and the adaptive arm of the immune system. (frontiersin.org)
The transplantation of a "foreign" organ, despite meticulous matching for donor-recipient compatibility, leads to a complex adaptive and innate immune system-mediated injury. (medscape.com)

Ablation of individual NELF subunits destabilizes the NELF complex and causes cell lethality, leading to the prevailing concept that NELF-mediated Pol II pausing is essential for cell proliferation. (bvsalud.org)

In particular, NK cells mediate their cytolytic function through the engagement of activating receptors, such as NKG2D, DNAM-1, NKp30, NKp46, and NKp44 ( 3 , 4 ), or following pro-inflammatory cytokine stimulation ( 5 ). (frontiersin.org)
While the antithrombotic activity of APC is based on its ability to inactivate clotting factors Va and VIIIa, leading to adverse bleeding, the cytoprotective effect is based on its anti-inflammatory, antiapoptotic, and endothelial barrier stabilization activities [ 12 , 14 ]. (biomedcentral.com)
The therapeutic effect of ADSCs expressing miR-26 on model mice was evaluated by detecting the levels of inflammatory factors and blood lipids in the serum of the mice. (amegroups.org)
ADSC-exos expressing miR-26 has positive effects on correcting blood lipids and inflammatory factors in the mouse model of CAS. (amegroups.org)

Because the mesothelial cells are the primary target cells of asbestos-induced molecular changes mediated through an oxidant-linked mechanism, we used normal mesothelial and malignant mesothelial cells to investigate alterations in molecular signaling in response to a commercially manufactured SWCNT. (cdc.gov)
HAV replicates exclusively in the cytoplasm of the infected hepatocytes by a mechanism involving an RNA-dependent RNA polymerase. (medscape.com)

These 30 amino acids may physically orient domains II and III to support functional interactions between TFIIS and RNA polymerase II. (embl.de)
Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III. (embl.de)

CDC's National Antimicrobial Resistance Monitoring System, in collaboration with the Food and Drug Administration (FDA) and the U.S. Department of Agriculture (USDA), will continue to look for mcr-1 mediated colistin resistance in enteric bacteria from humans, retail meat, and food animals. (cdc.gov)

We show that FBP21 is present in highly purified spliceosomal complex A, is associated with U2 snRNPs, and colocalizes with splicing factors in nuclear speckle domains. (embl.de)
In the reconstituted NER system, a higher level of incision of UV-damaged DNA is achieved with the Rad1-Rad10-Rad14 complex, which we designate as nucleotide excision repair factor-1, NEF-1. (utmb.edu)

Domain I is conserved in evolution from yeast to human species and is homologous to the transcription factors elongin A and CRSP70. (embl.de)
Domain III has previously been shown to be readily exchanged between mammalian and yeast factors. (embl.de)

GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1. (mayo.edu)

Following activation, NK cells mediate killing of target cells through two major pathways that require direct contact between NK cells and their target cells ( 6 ). (frontiersin.org)
However, the therapeutic efficacy is attenuated by the antitumor agent-induced activation of nuclear factor-κB (NF-κB). (oncotarget.com)

The canonical function of a bacterial sigma (σ) factor is to determine the gene specificity of the RNA polymerase (RNAP). (nih.gov)
In several diverse bacterial species, the σ 54 factor uniquely confers distinct functional and regulatory properties on the RNAP. (nih.gov)
[ 3 ] Immunoglobulins, complement, and bacterial antigens have all been identified by immunofluorescence, and in some cases mycobacterial DNA sequences have been found by polymerase chain reaction. (medscape.com)
Blood monocytes are "blood stream passengers" en route to various tissue compartments where they are involved in numerous functions, including defence mechanisms, producing coagulation factors and cytokines, and phagocytosing various bacterial constituents and cellular debris (apoptotic bodies). (thermofisher.com)

A conserved charged stretch in the linker region (residues 89-95, DPTLPR) mediated the interaction with RNA polymerase II. (embl.de)

Although advances in tissue typing and cross-match testing have helped to deter severe transplant rejection, rejection may result from direct cellular attack (cellular rejection) or be mediated by antibodies (humoral rejection). (medscape.com)

Combination of IMS (immunomagnetic separation) of monocytes from whole blood, mRNA isolation using Dynabeads Oligo (dT)25, reverse transcription (RT) and polymerase chain reaction (PCR) provides a powerful method for detecting such changes at the mRNA-level in activated monocytes. (thermofisher.com)
This patient also had positive result on polymerase chain reaction assay for herpes simplex virus, which is both sensitive and specific. (medscape.com)
Diagnosis is with MRI plus cerebrospinal fluid analysis using polymerase chain reaction testing. (msdmanuals.com)

Of the seven σ factors in Escherichia coli and related bacteria, σ 54 exists in a class of its own. (nih.gov)

DNA replication occurs once and only once per cell cycle mainly regulated by DNA replication initiation factors in eukaryotic cells. (intechopen.com)

Dynamic structure mediates halophilic adaptation of a DNA polymerases from the deep-sea brines of the Red sea. (edu.sa)
Comparison of the virulence and transmissibility of canine H3N2 influenza viruses and characterization of their canine adaptation factors. (cdc.gov)

Polyadenylation is essential for the stability of the transcript, preventing the mRNA from being the target of posttranscriptional gene silencing (PTGS) via RNA-dependent RNA polymerase 6 (RDR6) in plants ( Luo and Chen, 2007 ). (frontiersin.org)

Healthcare providers should follow Standard and Contact Precautions ( https://www.cdc.gov/hicpac/2007IP/2007ip_part3.html ) for any patients colonized or infected with antibiotic resistant bacteria, including patients who are found to have mcr-1 mediated resistant organisms. (cdc.gov)

Despite the sequence similarities, there are many factors that do not function across species. (embl.de)

In animals, the amount of juvenile growth is controlled by the coordinated timing of maturation and growth rate, which are strongly influenced by the environmental factors such as nutrient availability. (sdbonline.org)
A large number of studies have demonstrated that the synergistic collaboration of a number of microRNAs (miRNAs), their growth factors and their downstream agents is required for the initiation and completion of pathogenesis in the liver. (wjgnet.com)
On the other hand, ATF-3 is rapidly induced in cells treated with growth stimulators such as serum and growth factors [ 20 ]. (hindawi.com)

An enterovirus primer-mediated reverse in effectively controlling enteroviral infections. (cdc.gov)

Genotypic analysis of clinical and environmental Cryptococcus neoformans isolates from Brazil reveals the presence of VNB isolates and a correlation with biological factors. (cdc.gov)

Anatomy9

Organisms18

Chemicals and Drugs121

Analytical, Diagnostic and Therapeutic Techniques and Equipment35

Phenomena and Processes76

Disciplines and Occupations1

Information Science4

Health Care4

Poly-ADP-ribose4

Protein18

Immune-mediated5

Subunit4

Plasmid-mediated3

Genes9

Pathway8

Multisubunit1

Transcriptional2

Cytokine-mediated2

Immunohistochemistry2

Quantitative2

Cell-mediated5

PARP3

Tumor cell1

Regulation3

Binds2

Proteins3

Holoenzyme4

Cytotoxic1

Receptor5

Vascular3

Infection5

Elongation4

Apoptosis4

Repression1

Expression5

Adaptive2

NELF1

Inflammatory4

Mechanism2

Interactions2

Resistance1

Complex2

Yeast2

Regulator1

Activation2

Bacterial4

Linker1

Cellular1

Chain3

Escherichia1

Initiation factors1

Adaptation2

MRNA1

Organisms1

Sequence1

Growth3

Infections1

Correlation1