Meconium ileus. Medical search. Frequent questions

Meconium ileus (MI) is often the first manifestation of cystic fibrosis (CF) and occurs in approximately 20% of patients with diagnosed CF. (medscape.com)
This study was pursued as an extension of a randomized clinical investigation of neonatal screening for cystic fibrosis (CF). The objective was to determine if CF patients with meconium ileus (MI) were more likely to be malnourished compared with those without MI who were diagnosed during early infancy through neonatal screening. (nih.gov)
Meconium ileus is blockage of the small intestine in a newborn caused by excessively thick intestinal contents (meconium), usually as a result of cystic fibrosis. (msdmanuals.com)
Meconium ileus usually results from cystic fibrosis. (msdmanuals.com)
Newborns with meconium ileus almost always develop other symptoms of cystic fibrosis later. (msdmanuals.com)
Meconium ileus is the presenting clinical manifestation of cystic fibrosis in 10 to 20% of cases. (msdmanuals.com)
Meconium Ileus, Distal Intestinal Obstruction Syndrome, and Other Gastrointestinal Pathology in the Cystic Fibrosis Patient. (msdmanuals.com)
The failure to pass meconium is a symptom of several diseases including Hirschsprung's disease and cystic fibrosis. (wikipedia.org)
Meconium ileus is often the first sign of cystic fibrosis. (wikipedia.org)
In cystic fibrosis, the meconium can form a bituminous black-green mechanical obstruction in a segment of the ileum. (wikipedia.org)
About 20% of cases of cystic fibrosis present with meconium ileus, while approximately 20% of one series of cases of meconium ileus did not have cystic fibrosis. (wikipedia.org)
The presence of meconium ileus is not related to the severity of the cystic fibrosis. (wikipedia.org)
My perinatologist had told my husband and me that the biggest concern for newborns with cystic fibrosis is a bowel blockage -- meconium ileus -- that occurs in approximately one in every five babies born with the disease. (cff.org)
My research revealed exactly what meconium ileus is and how it is typically the first clinical manifestation of cystic fibrosis. (cff.org)
Despite reassuring doctors' visits, I always had a strong intuition our daughter had cystic fibrosis and that she would have meconium ileus. (cff.org)
In 1993, five children with cystic fibrosis (CF) were reported with what appeared to be meconium ileus equivalent, which did not respond to medical treatment, and four had thickening and strictures of the colon. (bmj.com)
Meconium ileus is the initial manifestation of cystic fibrosis in ca. 15% of affected newborns. (clinicalgate.com)
Meconium ileus (MI), a life-threatening intestinal obstruction due to meconium with abnormal protein content, occurs in approximately 15 percent of neonates with cystic fibrosis (CF). Analysis of twins with CF demonstrates that MI is a highly heritable trait, indicating that genetic modifiers are largely responsible for this complication. (ku.edu)
Thbaud b, abman sh bronchopulmonary dysplasia every cialis weekend obliterative bronchiolitis cystic fibrosis have meconium ileus. (elastizell.com)
Failure to pass a stool by 48 hours of life may signify a more serious condition, such as Hirschsprung's disease, meconium ileus due to cystic fibrosis, or hypothyroidism. (optimalhealthnetwork.com)

Meconium ileus (MI) is defined as an intestinal obstruction caused by impaction of inspissated meconium in the terminal ileum. (medscape.com)
In MI, low or distal intestinal obstruction results from impaction of thick, tenacious meconium in the distal small bowel. (medscape.com)
Meconium ileus is among the most common causes of intestinal obstruction in the newborn, accounting for 9-33% of neonatal intestinal obstructions. (medscape.com)
Here, we conduct a modifier gene study for meconium ileus (MI), an intestinal obstruction that occurs in 16-20% of CF newborns, providing linkage and association results from large family and case-control samples. (johnshopkins.edu)

Radiography is the preferred examination for evaluating cases of meconium ileus, meconium peritonitis, meconium ileus-equivalent syndrome, and meconium plug syndrome. (medscape.com)
By convention, 4 gastrointestinal conditions include the term meconium in their names: meconium ileus, meconium peritonitis, meconium ileus-equivalent syndrome, and meconium plug syndrome . (medscape.com)
Complications such as ileal atresia or stenosis, ileal perforation, meconium peritonitis, and volvulus with or without pseudocyst formation can occur in association with MI. (medscape.com)
Meconium peritonitis (MP) is a rare fetal disease that needs to be urgently identified for surgical intervention. (medscape.com)
Meconium peritonitis may be incidentally detected on abdominal radiographs. (medscape.com)
If the intestine loses its vascular supply and infarcts, sterile meconium peritonitis can result. (msdmanuals.com)
Calcifications in the abdominal wall can be seen in meconium peritonitis. (radiologyassistant.nl)
This child was born via emergency C-section and at age 2 weeks, had meconium ileus with perforation and DIC secondary to peritonitis. (contemporarypediatrics.com)
May lead to meconium peritonitis . (librepathology.org)

Medical staff may aspirate the meconium from the nose and mouth of a newborn immediately after delivery in the event the baby shows signs of respiratory distress to decrease the risk of meconium aspiration syndrome, which can occur in meconium-stained amniotic fluid. (wikipedia.org)
Meconium aspiration syndrome is "not common, but it's not rare either," says Daniel Ganjian , MD, a pediatrician at Providence Saint John's Health Center in Santa Monica, California. (thebump.com)
Meconium aspiration syndrome usually happens when baby is stressed due to a decrease in oxygen and blood supply, and passes meconium while still inside the uterus, according to the US National Library of Medicine . (thebump.com)
If your doctor suspects that baby has meconium aspiration syndrome, they'll usually order a chest X-ray, Ganjian says, and then decide if baby needs supplemental oxygen. (thebump.com)
About 1.5 percent of neonates with MSAF develop meconium aspiration syndrome. (hindawi.com)
5% of infants born through MSAF develop meconium aspiration syndrome (MAS) which is a real threat to many newborns worldwide, with a case fatality rate of 5% (as much as 40%), in addition to MAS short- and long-term pulmonary and neurodevelopmental sequelae which could occur [ 5 , 6 ]. (hindawi.com)

A possible meconium ileus diagnosis should raise the suspicion of CF in the fetus. (medscape.com)
Antenatal diagnosis of meconium ileus can be confirmed in 2 groups. (medscape.com)
In the low-risk group, the diagnosis is suspected when routine prenatal ultrasonography reveals the sonographic appearances of meconium ileus. (medscape.com)

Meconium ileus should be distinguished from meconium plug syndrome, in which a tenacious mass of mucus prevents the meconium from passing and there is no risk of intestinal perforation. (wikipedia.org)
Meconium ileus has a significant risk of intestinal perforation. (wikipedia.org)

Meconium ileus-equivalent syndrome" is the term applied to a partial small-bowel obstruction in an older patient with known CF. Although the bowel gas pattern may resemble that of MI, these findings are not due to meconium, which is present only in the newborn. (medscape.com)
Meconium Plug Syndrome Meconium plug syndrome is colonic obstruction caused by thick meconium. (msdmanuals.com)
In a barium enema, meconium plug syndrome shows a normal or dilated colon as compared to micro-colon in meconium ileus. (wikipedia.org)

Neonates with meconium pseudocysts do not require surgery if these cysts are not associated with the findings described here. (medscape.com)
After birth, unlike normal neonates, infants with meconium ileus do not pass meconium in the first 12 to 24 hours. (msdmanuals.com)

This is bowel obstruction secondary to thick, sticky meconium that won't move down the colon. (paediatricfoam.com)
The signs and symptoms are neonatal bowel obstruction, with vomiting, abdominal distension, and failure to pass meconium in the first 24 hours. (paediatricfoam.com)
A phenomenon called meconium ileus, a bowel obstruction in newborns, may also be the first sign. (check.in)

Newborns expel meconium almost always in the first 24 hours of life. (msdmanuals.com)
After birth, newborns usually pass meconium in the first 12 to 24 hours. (msdmanuals.com)
However, newborns with meconium ileus do not pass meconium within this time frame and also have symptoms of intestinal blockage, including vomiting and abdominal swelling. (msdmanuals.com)

Unlike later feces, meconium is composed of materials ingested during the time the infant spends in the uterus: intestinal epithelial cells, lanugo, mucus, amniotic fluid, bile, and water. (wikipedia.org)
Meconium is normally retained in the infant's bowel until after birth, but sometimes it is expelled into the amniotic fluid prior to birth or during labor and delivery. (wikipedia.org)
Some post-dates pregnancies (when they are more than 40 weeks pregnant) may also have meconium-stained amniotic fluid without fetal distress. (wikipedia.org)
Most of the time that the amniotic fluid is stained with meconium, it will be homogeneously distributed throughout the fluid, making it brown. (wikipedia.org)
Terminal meconium occurs when the fetus passes the meconium a short enough time before birth/cesarean section that the amniotic fluid remains clear, but individual clumps of meconium are in the fluid. (wikipedia.org)
When a baby has a meconium bowel movement before or during birth, the meconium can mix with amniotic fluid. (thebump.com)
Meconium should remain in the intestines during pregnancy, but sometimes infants pass some meconium that mixes in the amniotic fluid before delivery," says Susan J. Dulkerian , MD, chair of the department of pediatrics and medical director of newborn services in The Family Childbirth and Children's Center at Mercy Medical Center in Baltimore, Maryland. (thebump.com)
All babies breathe in-utero, she explains, and baby can "breathe in some of that amniotic fluid that is mixed with meconium, causing problems such as breathing difficulties to a severe pneumonia and respiratory failure in the worst cases. (thebump.com)
Using a novel assay termed prooxidant-antioxidant balance (PAB) assay to determine prooxidant-antioxidant balance in umbilical cord blood of infants with meconium stained of amniotic fluid (MSAF). (hindawi.com)
Passage of meconium in amniotic fluid is associated with increase of neonatal mortality and morbidity. (hindawi.com)
Meconium is composed of desquamated cells from the intestine and skin, gastrointestinal mucin, lanugo hair, fatty material from the vernix caseosa, amniotic fluid, and intestinal secretions. (hindawi.com)
Meconium-stained amniotic fluid (MSAF) can cause mechanical obstruction of airways and pulmonary air leak, pneumonitis, vasoconstriction of pulmonary vessels, and inactivation of surfactant effect which could result in pulmonary inflammation and apoptosis. (hindawi.com)
7% to 20% of deliveries at term have meconium in the amniotic fluid, which would reach to 40% in postterm deliveries [ 4 ]. (hindawi.com)

The prognosis for infants presenting with both simple and complicated meconium ileus has improved with the advancement of both nonoperative and operative treatments, along with good nutritional support and better treatment of bacterial infections. (medscape.com)
Infants with meconium ileus are at risk for cholestasis, particularly if they have received or are receiving total parenteral nutrition (TPN). (medscape.com)

is a dangerous condition because it causes meconium to leak into the abdominal cavity. (msdmanuals.com)
What causes meconium aspiration? (thebump.com)

If the meconium is abnormally thick or tarlike, it can block the last part of the small intestine, called the ileum. (msdmanuals.com)
Meconium is thick and sticky-and that's totally normal. (thebump.com)
Approximately 90% of cases of meconium ileus are in babies with CF . When it's removed in theatre, the meconium is thick and squidgy like chewing gum that has been chewed for about 4 hours. (paediatricfoam.com)

However, babies occasionally pass meconium while still in-utero, and this can potentially cause complications. (thebump.com)

Distal to the obstruction, the colon is narrow and empty or contains small amounts of desiccated meconium pellets. (msdmanuals.com)

Imperforate anus and meconium ileus. (brainscape.com)

Meconium ileus accounts for up to 33% of neonatal small-bowel obstructions. (msdmanuals.com)

According to research , in-utero meconium passage happens in about 12 to 20 percent of births-and up to 40 percent of births that go past their due date. (thebump.com)
The inspissation of bowel contents due to abnormal intestinal secretions prevents the normal passage of meconium. (clinicalgate.com)

Other insects, such as beetles and some Hymenoptera (Aculeata) expel the meconium at the end of the larval stage, before becoming a pupa. (wikipedia.org)

Common digestive symptoms include foul-smelling greasy stools, pale or clay-colored stools, poor weight gain/growth, meconium ileus, severe constipation, increased gas or bloating or a swollen belly, nausea, and loss of appetite. (fortherecordmag.com)

Expulsion of meconium from the intestinal lumen into the amniotic cavity is a consequence of increased intestinal peristalsis and of anal sphincter relaxation resulting from vagal stimulation [ 3 ]. (hindawi.com)

Meconium, unlike later feces, is viscous and sticky like tar - its color usually being a very dark olive green and it is almost odorless. (wikipedia.org)
The viscous meconium sometimes contains small air bubbles. (clinicalgate.com)

Symptoms include emesis that may be bilious, abdominal distention, and failure to pass meconium in the first several days of life. (msdmanuals.com)

It's a little-known fact outside of parenting circles: Babies have a first poop called meconium, and it's unlike any other BM you've seen. (thebump.com)
For the record, it's normal-and expected-for babies to pass meconium after birth. (thebump.com)

In the simple form, thickened meconium begins to form in utero. (medscape.com)
Meconium can be tested for various drugs, to check for in utero exposure. (wikipedia.org)

Symptoms in the newborn period include failure to pass the meconium within a short time after birth. (rarediseases.org)

The issue of whether meconium is sterile remains debated and is an area of ongoing research. (wikipedia.org)
Other researchers have raised questions about whether these findings may be due to contamination after sample collection and that meconium is, in fact, sterile until after birth. (wikipedia.org)

[ 1 ] The inspissated meconium obstructs the small intestine at the level of the terminal ileum. (medscape.com)
When contrast medium enters the terminal ileum, the radiograph shows irregular filling defects caused by inspissated meconium. (clinicalgate.com)

This indicates that the fetus passed the meconium some time ago such that sufficient mixing occurred as to establish the homogeneous mixture. (wikipedia.org)
The Latin term meconium derives from Greek μηκώνιον, mēkōnion, a diminutive of μήκων, mēkōn 'poppy', in reference either to its tar-like appearance that may resemble some raw opium preparations or to Aristotle's belief that it induces sleep in the fetus. (wikipedia.org)

The meconium sometimes becomes thickened and congested in the intestines, a condition known as meconium ileus. (wikipedia.org)

Meconium is the material found in the intestine of a newborn. (medscape.com)
is similar to meconium ileus except that it is the large intestine that is blocked by meconium. (msdmanuals.com)
Meconium is the dark sticky substance that is normally present in the intestine at birth and is passed as an infant's first bowel movement after birth. (rarediseases.org)

Meconium, a dark green substance, is a newborn's first stool. (msdmanuals.com)
Meconium is the earliest stool of a mammalian infant resulting from defecation. (wikipedia.org)

Black-green color of meconium is due to the presence of bile pigments [ 1 , 2 ]. (hindawi.com)

No meconium is passed, and abdominal distension and vomiting appear soon after birth. (wikipedia.org)
If your doctor realizes that baby has passed meconium before or during birth, they'll work to determine a plan of action. (thebump.com)

Anatomy1

Diseases8

Chemicals and Drugs1

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Named Groups1

Health Care1

Cystic fibrosis20

Intestinal obstruction4

Peritonitis9

Aspiration syndrome6

Diagnosis3

Perforation2

Syndrome3

Neonates2

Bowel obstruction3

Newborns3

Amniotic fluid13

Infants2

Causes meconium2

Thick3

Complications1

Obstruction1

Imperforate1

Small bowel1

Passage2

Expel1

Stools1

Vagal1

Viscous2

Abdominal distention1

Babies2

Utero2

Symptoms1

Sterile2

Terminal2

Fetus2

Intestines1

Intestine3

Stool2

Bile1

Birth2