Mechanism of act gyrase and topoisomerase fluoroquinolones. Medical search. Frequent questions

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Anatomy7

Tumor Cells, Cultured Cell Line HeLa Cells Cell Nucleus Cell Line, Tumor Chromosomes, Bacterial HL-60 Cells

Organisms40

Escherichia coli Streptococcus pneumoniae Staphylococcus aureus Mycoplasma hominis Pseudomonas aeruginosa Gram-Positive Bacteria Clostridium difficile Mycobacterium fortuitum Gram-Negative Bacteria Mycobacterium smegmatis Bacteria Neisseria gonorrhoeae Mycobacterium tuberculosis Sulfolobus Salmonella typhi Laurus Bartonella bacilliformis Gram-Positive Cocci Campylobacter Moraxella (Branhamella) catarrhalis Saccharomyces cerevisiae Klebsiella pneumoniae Salmonella paratyphi A Salmonella enterica Bacteria, Anaerobic Crithidia fasciculata Enterobacteriaceae Micrococcus Bacteroides fragilis Archaeoglobus fulgidus Haemophilus influenzae Bacteriophage mu Cricetinae Enterococcus faecalis Campylobacter jejuni Thermotoga maritima Leishmania donovani Mycobacterium Acinetobacter Vaccinia virus

Diseases30

Dermatitis, Phototoxic Gram-Negative Bacterial Infections Pneumococcal Infections Bacterial Infections Typhoid Fever Community-Acquired Infections Urinary Tract Infections Escherichia coli Infections Enterocolitis, Pseudomembranous Paratyphoid Fever Cross Infection Gram-Positive Bacterial Infections Otitis Externa Gonorrhea Leukemia P388 Respiratory Tract Infections Campylobacter Infections Extensively Drug-Resistant Tuberculosis Clostridium Infections Pseudomonas Infections Eye Infections, Bacterial Leukemia L1210 Tuberculosis, Multidrug-Resistant Staphylococcal Infections Dermatitis, Photoallergic Klebsiella Infections Salmonella Infections Pneumonia, Bacterial Bacteremia Tendinopathy

Chemicals and Drugs104

Fluoroquinolones DNA Gyrase DNA Topoisomerases, Type II Topoisomerase II Inhibitors DNA Topoisomerases, Type I Topoisomerase I Inhibitors DNA Topoisomerase IV Anti-Infective Agents DNA, Superhelical Ofloxacin Novobiocin Quinolones Ciprofloxacin Aza Compounds Topoisomerase Inhibitors Levofloxacin Anti-Bacterial Agents Aminocoumarins Norfloxacin 4-Quinolones Naphthyridines Pefloxacin Amsacrine Quinolines Oxolinic Acid Enoxacin Teniposide Nalidixic Acid DNA Topoisomerases Camptothecin Coumarins DNA, Bacterial Etoposide DNA DNA, Catenated Bacterial Proteins Razoxane Enzyme Inhibitors Ellipticines Antigens, Neoplasm Intercalating Agents DNA-Binding Proteins Topotecan Macrolides Antineoplastic Agents, Phytogenic Fleroxacin Podophyllotoxin Antitubercular Agents beta-Lactams Antineoplastic Agents Aminoglycosides Adenylyl Imidodiphosphate Adenosine Triphosphate Nitrofurantoin Capreomycin Adenosine Triphosphatases DNA, Kinetoplast Aminoacridines DNA, Circular Escherichia coli Proteins Thiobarbiturates Piperazines Anti-Infective Agents, Urinary Cephalosporins Nucleic Acid Synthesis Inhibitors beta-Lactamases Isoenzymes Indenes Ethidium DNA Helicases Doxorubicin DNA Primers Rifampin Quinazolinones DNA, Single-Stranded Trimethoprim-Sulfamethoxazole Combination Aclarubicin Tetracyclines Carbapenems Recombinant Proteins Mitoxantrone Ethambutol DNA, Neoplasm Dioxolanes Lactams Erythromycin RecQ Helicases DNA, Viral Membrane Transport Proteins Hexylresorcinol Ketolides Macromolecular Substances Minocycline Antibiotics, Antineoplastic Oxazines Oligodeoxyribonucleotides Naphthoquinones Archaeal Proteins Bacterial Outer Membrane Proteins Distamycins Reserpine Multidrug Resistance-Associated Proteins Streptogramin B Acridines

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Microbial Sensitivity Tests Cloning, Molecular Sequence Analysis, DNA Models, Molecular Polymerase Chain Reaction Amino Acid Substitution Electrophoresis, Agar Gel Drug Screening Assays, Antitumor Area Under Curve Electrophoresis, Gel, Pulsed-Field Inhibitory Concentration 50 Reverse Transcriptase Polymerase Chain Reaction Chromatography, Supercritical Fluid Serum Bactericidal Test Colony Count, Microbial Models, Biological Ribotyping Drug Design Electrophoresis, Polyacrylamide Gel Mutagenesis, Site-Directed

Phenomena and Processes55

DNA, Superhelical Drug Resistance, Bacterial Drug Resistance, Microbial Mutation Drug Resistance, Multiple, Bacterial DNA, Catenated Plasmids DNA Cleavage Base Sequence DNA Damage Genes, Bacterial Nucleic Acid Conformation Amino Acid Sequence Drug Resistance, Multiple DNA Replication Structure-Activity Relationship Substrate Specificity Catalysis Kinetics Binding Sites DNA, Circular Dose-Response Relationship, Drug Protein Binding Drug Resistance Amino Acid Substitution Point Mutation Phenotype Molecular Structure Hydrolysis Area Under Curve Inhibitory Concentration 50 Cell Cycle Transcription, Genetic Drug Interactions Gene Expression Regulation, Bacterial Cell Survival DNA, Single-Stranded Protein Structure, Tertiary beta-Lactam Resistance Sequence Homology, Amino Acid Recombination, Genetic Drug Resistance, Neoplasm DNA Repair SOS Response (Genetics)Microbial Viability Mitosis Protein Conformation Time Factors Chromosomes, Bacterial Drug Synergism Cephalosporin Resistance Molecular Weight Phylogeny Apoptosis Ultraviolet Rays

Disciplines and Occupations1

Information Science4

Molecular Sequence Data Base Sequence Amino Acid Sequence Phylogeny

Health Care4

Drug Utilization Area Under Curve Hospitals Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

Fluoroquinolones DNA Gyrase DNA Topoisomerases, Type II Topoisomerase II Inhibitors DNA Topoisomerases, Type I Topoisomerase I Inhibitors DNA Topoisomerase IV Anti-Infective Agents DNA, Superhelical Ofloxacin Novobiocin Quinolones Ciprofloxacin Microbial Sensitivity Tests Aza Compounds Topoisomerase Inhibitors Levofloxacin Anti-Bacterial Agents Aminocoumarins Drug Resistance, Bacterial Norfloxacin 4-Quinolones Naphthyridines Pefloxacin Drug Resistance, Microbial Amsacrine Quinolines Oxolinic Acid Enoxacin Teniposide Escherichia coli Nalidixic Acid DNA Topoisomerases Camptothecin Coumarins DNA, Bacterial Mutation Streptococcus pneumoniae Molecular Sequence Data Drug Resistance, Multiple, Bacterial Etoposide DNA DNA, Catenated Plasmids DNA Cleavage Base Sequence Bacterial Proteins Dermatitis, Phototoxic Staphylococcus aureus Razoxane Enzyme Inhibitors Ellipticines DNA Damage Antigens, Neoplasm Mycoplasma hominis Intercalating Agents DNA-Binding Proteins Genes, Bacterial Nucleic Acid Conformation Amino Acid Sequence Gram-Negative Bacterial Infections Topotecan Macrolides Antineoplastic Agents, Phytogenic Fleroxacin Pseudomonas aeruginosa Podophyllotoxin Drug Resistance, Multiple Antitubercular Agents DNA Replication Gram-Positive Bacteria Structure-Activity Relationship beta-Lactams Antineoplastic Agents Aminoglycosides Clostridium difficile Pneumococcal Infections Bacterial Infections Typhoid Fever Mycobacterium fortuitum Gram-Negative Bacteria Adenylyl Imidodiphosphate Cloning, Molecular Adenosine Triphosphate Nitrofurantoin Substrate Specificity Catalysis Mycobacterium smegmatis Kinetics Capreomycin Sequence Analysis, DNA Community-Acquired Infections Adenosine Triphosphatases Binding Sites DNA, Kinetoplast Aminoacridines DNA, Circular Models, Molecular Drug Utilization Urinary Tract Infections

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