Mechanism enhances protein kinase inhibitors. Medical search. Frequent questions

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Anatomy16

Cells, Cultured Cell Line Tumor Cells, Cultured Cell Line, Tumor 3T3 Cells Cell Nucleus HeLa Cells Cytosol Fibroblasts Cell Membrane PC12 Cells Neurons Myocardium Muscle, Smooth, Vascular CHO Cells Epithelial Cells

Organisms7

Rats, Sprague-Dawley Cattle Rabbits Rats, Wistar Cricetinae Mice, Inbred C57BL Mice, Knockout

Chemicals and Drugs172

Protein Kinase Inhibitors Protein Kinase C Protein Kinases Cyclic AMP-Dependent Protein Kinases Staurosporine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Enzyme Inhibitors Protein-Serine-Threonine Kinases Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases Isoquinolines Phosphatidylinositol 3-Kinases Alkaloids Indole Alkaloids Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 1 Carbazoles Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinase 3 Tetradecanoylphorbol Acetate JNK Mitogen-Activated Protein Kinases Cyclic GMP-Dependent Protein Kinases Cyclic AMP Protein Kinase C-alpha Piperazines Indoles Protein Kinase C-delta src-Family Kinases Pyridines Isoenzymes AMP-Activated Protein Kinases Pyrimidines Genistein Cyclin-Dependent Kinases Intracellular Signaling Peptides and Proteins Calcium Flavonoids Protein Kinase C-epsilon CDC2 Protein Kinase Protein Kinase C beta Maleimides Casein Kinase II Imidazoles Cyclin-Dependent Kinase Inhibitor p27 Phosphoproteins RNA, Messenger Proto-Oncogene Proteins c-akt Calcium-Calmodulin-Dependent Protein Kinase Type 2 Cyclin-Dependent Kinase Inhibitor p21 Proto-Oncogene Proteins Sulfonamides Extracellular Signal-Regulated MAP Kinases Chromones Androstadienes MAP Kinase Kinase 1 Okadaic Acid Carrier Proteins Benzamides Phorbol 12,13-Dibutyrate Phorbol Esters Morpholines MAP Kinase Kinase Kinases Casein Kinases rho-Associated Kinases Recombinant Proteins Serine Antineoplastic Agents Adenosine Triphosphate Phosphoprotein Phosphatases Diglycerides p21-Activated Kinases Cyclic AMP-Dependent Protein Kinase Type II Tyrosine eIF-2 Kinase Butadienes Nitriles Ribosomal Protein S6 Kinases Pyrroles Ethers, Cyclic Receptor Protein-Tyrosine Kinases MAP Kinase Kinase 4 Receptor, Epidermal Growth Factor Recombinant Fusion Proteins Phosphotransferases (Alcohol Group Acceptor)Naphthalenes Colforsin Protamine Kinase Cell Cycle Proteins Isoflavones DNA-Binding Proteins Quinazolines Cyclic GMP Benzophenanthridines Aurora Kinases Mitogen-Activated Protein Kinase 14 Glycogen Synthase Kinase 3 Phenanthridines Myosin-Light-Chain Kinase Transcription Factors Cyclins Tyrphostins DNA-Activated Protein Kinase 2-Aminopurine Pyrazoles 8-Bromo Cyclic Adenosine Monophosphate CDC2-CDC28 Kinases 3-Phosphoinositide-Dependent Protein Kinases Creatine Kinase Thiazoles Thionucleotides Threonine Pyruvate Kinase Phosphotyrosine Membrane Proteins Nuclear Proteins Proteins Ribosomal Protein S6 Kinases, 90-kDa Diacylglycerol Kinase Mitogen-Activated Protein Kinase 8 NF-kappa B Phosphoserine I-kappa B Kinase MAP Kinase Kinase 2 MAP Kinase Kinase Kinase 1 DNA Primers Calmodulin Actins 1-Phosphatidylinositol 4-Kinase Peptides RNA, Small Interfering Thymidine Kinase TOR Serine-Threonine Kinases Cyclin-Dependent Kinase Inhibitor p57 Oxazoles Cyclic AMP Response Element-Binding Protein Cyclin-Dependent Kinase 2 Epidermal Growth Factor Tumor Necrosis Factor-alpha 1-Methyl-3-isobutylxanthine Cyclin-Dependent Kinase Inhibitor Proteins Kinetin Bucladesine Focal Adhesion Kinase 1 Type C Phospholipases Tumor Suppressor Proteins DNA Focal Adhesion Protein-Tyrosine Kinases Insulin Cycloheximide Adaptor Proteins, Signal Transducing Cyclic GMP-Dependent Protein Kinase Type I Anthracenes MAP Kinase Kinase 6 Purines MAP Kinase Kinase 3 Janus Kinase 2 Transcription Factor AP-1 Death-Associated Protein Kinases Protein Isoforms Enzyme Activators Calcimycin Multienzyme Complexes Aurora Kinase A Egtazic Acid Ionomycin Calcium-Calmodulin-Dependent Protein Kinase Kinase Amides A Kinase Anchor Proteins Mitogen-Activated Protein Kinase 9 Glucose Protein Phosphatase 1

Analytical, Diagnostic and Therapeutic Techniques and Equipment15

Blotting, Western Transfection Immunoblotting Models, Biological Cloning, Molecular Precipitin Tests Mutagenesis, Site-Directed Reverse Transcriptase Polymerase Chain Reaction Electrophoresis, Polyacrylamide Gel Inhibitory Concentration 50 Models, Molecular Microscopy, Fluorescence Peptide Mapping Drug Design Blotting, Northern

Phenomena and Processes42

Phosphorylation Enzyme Activation MAP Kinase Signaling System Signal Transduction Kinetics Amino Acid Sequence Dose-Response Relationship, Drug Transfection Apoptosis Protein Binding Mutation Cell Division Substrate Specificity Base Sequence Cell Cycle Time Factors Binding Sites Gene Expression Regulation Down-Regulation Transcription, Genetic Cell Proliferation Gene Expression Regulation, Enzymologic Protein Structure, Tertiary Cell Survival Sequence Homology, Amino Acid Second Messenger Systems Up-Regulation Gene Expression Biological Transport Drug Synergism Cell Differentiation Molecular Weight Promoter Regions, Genetic Enzyme Induction Structure-Activity Relationship Mitosis Transcriptional Activation Inhibitory Concentration 50 Drug Resistance, Neoplasm Protein Transport G1 Phase Cell Movement

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Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Anatomy Organisms Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science

Protein Kinase Inhibitors Protein Kinase C Protein Kinases Cyclic AMP-Dependent Protein Kinases Staurosporine Phosphorylation 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Enzyme Inhibitors Protein-Serine-Threonine Kinases Calcium-Calmodulin-Dependent Protein Kinases Mitogen-Activated Protein Kinases p38 Mitogen-Activated Protein Kinases Isoquinolines Phosphatidylinositol 3-Kinases Enzyme Activation Alkaloids MAP Kinase Signaling System Signal Transduction Indole Alkaloids Protein-Tyrosine Kinases Mitogen-Activated Protein Kinase 1 Carbazoles Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinase 3 Cells, Cultured Tetradecanoylphorbol Acetate JNK Mitogen-Activated Protein Kinases Cyclic GMP-Dependent Protein Kinases Cyclic AMP Protein Kinase C-alpha Piperazines Indoles Protein Kinase C-delta Cell Line src-Family Kinases Pyridines Isoenzymes Molecular Sequence Data Kinetics AMP-Activated Protein Kinases Pyrimidines Genistein Cyclin-Dependent Kinases Intracellular Signaling Peptides and Proteins Calcium Amino Acid Sequence Flavonoids Protein Kinase C-epsilon CDC2 Protein Kinase Protein Kinase C beta Maleimides Casein Kinase II Imidazoles Dose-Response Relationship, Drug Cyclin-Dependent Kinase Inhibitor p27 Blotting, Western Phosphoproteins Transfection RNA, Messenger Tumor Cells, Cultured Apoptosis Proto-Oncogene Proteins c-akt Calcium-Calmodulin-Dependent Protein Kinase Type 2 Cyclin-Dependent Kinase Inhibitor p21 Proto-Oncogene Proteins Sulfonamides Extracellular Signal-Regulated MAP Kinases Chromones Androstadienes Cell Line, Tumor MAP Kinase Kinase 1 Protein Binding Mutation Okadaic Acid Carrier Proteins Benzamides Phorbol 12,13-Dibutyrate Phorbol Esters Morpholines MAP Kinase Kinase Kinases Cell Division Casein Kinases rho-Associated Kinases Substrate Specificity Recombinant Proteins Serine Antineoplastic Agents Base Sequence Adenosine Triphosphate Phosphoprotein Phosphatases Diglycerides p21-Activated Kinases Cell Cycle Cyclic AMP-Dependent Protein Kinase Type II Tyrosine eIF-2 Kinase Time Factors Butadienes Nitriles Ribosomal Protein S6 Kinases

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