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LectinsPlant LectinsLectins, C-TypeCytochrome c GroupMolecular Sequence DataAmino Acid SequenceMannose-Binding LectinsWheat Germ AgglutininsGalectinsSperm MaturationGlycoconjugatesPeanut AgglutininConcanavalin ACarbohydratesSexual MaturationOocytesGalactosidesAcetylgalactosamineGalanthusCell DifferentiationFetuinsReceptors, MitogenHemagglutinationCarbohydrate MetabolismAgglutinationMannoseOogenesisCarbohydrate SequenceCanavaliaArtocarpusDendritic CellsPolysaccharidesGlycoproteinsCells, CulturedGalactoseRicinusHemagglutininsRibosome Inactivating Proteins, Type 2AgglutininsHemagglutination TestsGlycosylationFucoseAsialoglycoproteinsMannosidesProtein BindingMeiosisAcetylglucosamineChromatography, AffinityOligosaccharidesMistletoePlants, MedicinalFabaceaeRibosome Inactivating ProteinsIn Vitro Oocyte Maturation TechniquesN-Acetylneuraminic AcidElectrophoresis, Polyacrylamide GelBinding SitesHistocytochemistryPhytohemagglutininsReceptors, N-AcetylglucosamineMethylmannosidesCell LineBase SequenceAbrinSeedsMonosaccharidesGlia Maturation FactorMice, Inbred C57BLGalectin 1ErythrinaSialic AcidsRNA, MessengerSambucusReceptors, Concanavalin ASequence Homology, Amino AcidCell MembraneProtein Processing, Post-TranslationalCarbohydrate ConformationAnimals, NewbornGalectin 3Receptors, Cell SurfaceMembrane ProteinsAgglutination TestsMolecular WeightOvarian FollicleGlycosidesMembrane GlycoproteinsNeuraminidaseCastor BeanCollectinsRecombinant ProteinsGalectin 4PhagosomesSignal TransductionMutationErythrocytesT-LymphocytesTime FactorsCumulus CellsEpididymis
DifferentiationReceptorsMiceSecretionProteinsAntigenImmatureCalnexinNephronInflammationGlycoproteinsExpressionLymphocytesVitroChaperonesFunctionalEndoplasmic reticulumLipopolysaccharideStimulateProteinPhenotypeInnate immunityEpithelialHumanViralMolecularRoleCalciumDomainDemonstrateTissuesImmuneStateDiabetesDomainsKeywordsHigh
Differentiation4
  • We have previously shown that the sialic acid-containing (Sia + ) fraction of intravenous immune globulin (IVIG) influences cell surface marker expression and cytokine/ chemokine secretion during the differentiation and maturation of human dendritic cells (DC). (scirp.org)
  • Zoom lens fibers cell differentiation is certainly an extremely coordinated process regarding specific adjustments in gene appearance between two different cell types. (antiviralbiologic.com)
  • it can also stimulate immunity, influencing the maturation and differentiation of T lymphocytes. (herbsofthesaints.com)
  • By creating IFN-, TNF-, IL-10, and chemokines, this NK subset modulates additional subsets of lymphocytes mainly, regulating dendritic cell maturation therefore, differentiation of helper T cells, and B- and T-cell-specific immune system reactions (29, 30). (biospraysehatalami.com)
Receptors5
  • While CD4 T cells are by far the most abundant HIV-infected cell, DCs express a variety of HIV co-receptors and lectin receptors that modulate HIV uptake, antigen processing, and trans-infection to T cells, thus contributing to a wide variety of immunological outcomes. (jscimedcentral.com)
  • Immature DCs possess a wide variety of receptors, such as Fc receptors, lectins, and langerin, which allow them to efficiently bind and internalize antigen. (jscimedcentral.com)
  • Self-recognition of MHC-I proteins through C-type lectin receptor NKG2A and inhibitory killer cell immunoglobulin-like receptors (KIRs) represent the physiological discussion between NK and focus on cells. (biospraysehatalami.com)
  • The responses are initiated when pathogen-associated or damage-associated molecular patterns are recognized by specific cell surface receptors such as Toll-like receptors (TLRs) and C-type lectin receptors or cytoplasmic proteins including the retinoic acid-inducible gene (RIG)-I-like receptors and NOD-like receptors (NLRs)1. (docksci.com)
  • Several human chemokine receptors have been sons than for those homozygous for the wild classified as such on the basis of similarity of type CCR5 (12,17-19,23). (cdc.gov)
Mice2
  • Kidney development in kat2J homozygous mice is aberrant early, before the appearance of gross cysts: developing cortical zones are thin, populated by immature glomeruli, and characterized by excessive apoptosis of several cell types. (biomedcentral.com)
  • By embryonic day 15.5, kidneys of nephron progenitor cell-specific VHL knockout mice begin to exhibit reduced maturation of nephron progenitors. (lww.com)
Secretion1
  • Coincidently, p58IPK deletion intensified NLRP3-inflammasome activation indicated by enhanced caspase 1 cleavage and increased IL-1β maturation and secretion. (docksci.com)
Proteins4
  • In many mitogenic and developmental proteins such as Notch and Delta the EGF-like domains are only of the hEGF type. (wikipedia.org)
  • In addition to the aforementioned three disulfide hEGF- and cEGF-like types, there are proteins carrying a four-disulfide EGF-like domain like laminin and integrin. (wikipedia.org)
  • Selectins, a group of proteins that are involved in leukocyte rolling towards a source of inflammation, contain an EGF-like domain along with a lectin domain and short consensus repeats (SCRs). (wikipedia.org)
  • Proteins that undergo maturation in the ER are stabilized SOS2 by chaperones such as calnexin and calreticulin, which are structurally related and identify glycosylated, nonnative proteins through lectin-like domains. (phytid.org)
Antigen1
  • We have previously demonstrated that the C-type lectin macrophage galactose-type lectin (MGL), expressed by human antigen presenting cells, can distinguish healthy tissue from CRC through its specific recognition of Tn antigen. (oncotarget.com)
Immature3
  • To analyze the interactions between M. tuberculosis and immune cells, human peripheral blood monocyte-derived immature DCs were infected with M. tuberculosis H37Rv wild type strain and flow cytometry was used to analyse cell surface expression markers. (biomedcentral.com)
  • These data clearly demonstrate that M. tuberculosis induces activation and maturation of human monocyte-derived immature DC as well as induces T cell proliferation in vitro . (biomedcentral.com)
  • DC) maturation, removal of immature tolerogenic DCs, and their capability to make immunoregulatory cytokines. (biospraysehatalami.com)
Calnexin2
  • These studies showed that a "chaperone" protein called calnexin, which facilitates this type of folding, regulates VLP entry into host cells. (futurity.org)
  • B) Calnexin includes a globular lectin domains (yellowish) and a protracted arm domains (silver). (phytid.org)
Nephron1
  • Our studies indicate that Nek1 deficiency leads to disordered kidney maturation, and cysts throughout the nephron. (biomedcentral.com)
Inflammation1
  • CD11c(low) langerin+ cells represent skin-derived Langerhans cells, as demonstrated by their high expression of DEC-205/CD205, maturation markers, and recruitment to skin-draining lymph nodes upon imiquimod-induced inflammation. (cnrs.fr)
Glycoproteins1
  • This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. (enquirebio.com)
Expression6
  • Our data indicate that the Sia + fraction of IVIG possesses the ability to influence inflammatory processes in multiple immune cell types and induces novel signatures in cell surface marker expression and cytokine/chemokine production. (scirp.org)
  • Differential expression of putative immune response genes (apextrin, complement C3, and two CELIII type lectin genes) was monitored in Acropora millepora juveniles for six months post-settlement, to explore the molecular basis of allorecognition maturation. (edu.au)
  • Using quantitative real-time PCR (qPCR), I found that expression of the lectin gene A036-E7 peaked and was significantly greater in the fourth month than at any other time for the majority of coral juveniles sampled. (edu.au)
  • Increased expression levels of one lectin gene may be linked to allorecognition maturation, or alternatively may represent a response to non-self recognition challenges. (edu.au)
  • Nek1 is detectable in all murine tissues but its expression in wild type and kat2J heterozygous kidneys decrease as the kidneys mature, especially in tubular epithelial cells. (biomedcentral.com)
  • To your knowledge, this is actually the initial study determining the appearance of 254 lengthy intergenic non-coding RNAs (lincRNAs) within the zoom lens, which 86 lincRNAs shown differential expression between your two cell types. (antiviralbiologic.com)
Lymphocytes2
  • Les IgIV intéragissent avec de nombreux composants du système immunitaire comme les récepteurs Fc, le complément, les cytokines, les lymphocytes T et B, les cellules dendritiques, les granulocytes et les cellules NK, ce qui explique en partie leurs effets anti-inflammatoires. (academie-medecine.fr)
  • 4 According to the number of tumor-infiltrating lymphocytes, tumors can be divided into three phenotypes: immune-inflamed, immune-excluded, and immune-desert types. (nature.com)
Vitro2
  • Fructo-oligosaccharides modify human DC maturation and peanut induced autologous T-cell response of allergic patients in vitro. (uu.nl)
  • 1998. Influence of organochlorine pesticides on maturation and post-fertilization development of bovine oocytes in vitro . (cdc.gov)
Chaperones3
  • In seeking to understand folding mechanics, his team investigated the roles of various intracellular carbohydrate-binding "chaperones" or "lectins" that assist with synthesis of the spike. (futurity.org)
  • We consider a number of the best-characterized chaperones today, which we classify into three wide functional types: holding, unfolding and folding. (phytid.org)
  • As an initial type of defence against harming cellular insults, many chaperones, including Hsp70s and sHsps, can stabilize protein undergoing denaturation and invite their refolding when the strain provides subsided. (phytid.org)
Functional3
  • We discovered that specific N-glycans seem to regulate the development and functional maturation of the SARS-CoV-2 spike protein," Neelamegham says. (futurity.org)
  • We found that efficient gene transfer into pDC can be achieved with VSVG-pseudotyped lentiviral vectors (LV) under the control of phoshoglycerate kinase (PGK) and elongation factor-1 (EF1α) promoters (28% to 90% of E-GFP + cells, respectively) in the absence of phenotypic and functional maturation. (biomedcentral.com)
  • The innate Lectin-like transcript 1 (LLT1) is known to be expressed on B-cells, but its functional role in the GC reaction has not been explored. (ox.ac.uk)
Endoplasmic reticulum2
Lipopolysaccharide1
  • Lipopolysaccharide (LPS) from Salmonella abortus equi , a known DC maturation agent, was used as a positive control and showed a comparable up regulation of cell surface markers as observed with M. tuberculosis infected DC. (biomedcentral.com)
Stimulate1
  • HIV uptake by DCs is unique in that it does not preferentially drive DC maturation and stimulate T cell instruction, but rather favors viral spread [10]. (jscimedcentral.com)
Protein4
  • CD22 molecule is a transmembrane protein from SIGLEC (Sialic acid-binding immunoglobulin-type lectins) family. (biomedcentral.com)
  • Imperative to this response can be an upsurge in chaperone and proteolytic actions, targeted at reducing the current presence of harming nonnative protein types. (phytid.org)
  • protein_coding" "Cz05g27200.t1","No alias","Chromochloris zofingiensis","SAM-dependent methyltransferase RsmB/NOP2-type [Interproscan]. (ntu.edu.sg)
  • C-reactive protein,mannose-binding lectin, and serum amyloid P component activate complement and act as opsonins. (msdmanuals.com)
Phenotype1
  • Using this co-culture model, bacterial CpG DNA (a Toll like receptor 9 ligand) combined with NDO was found to effectively drive away from the allergic phenotype of the underlying immune cells by increasing epithelial release of galectin-9, a soluble type lectin known to neutralize IgE and instruct regulatory T-cells. (uu.nl)
Innate immunity1
  • Although my data are preliminary, they confirm, as highlighted by recent studies of A. millepora, the crucial role lectins may play in the allorecognition and innate immunity of corals. (edu.au)
Epithelial2
  • The mammalian zoom lens comprises of just two cell types: epithelial cells, which comprise a monolayer of cells that series the anterior hemisphere from the zoom lens, and fibers cells, which will make up the rest from the zoom lens mass. (antiviralbiologic.com)
  • Since that time, many other much less numerous and even more local populations of astrocytes have already been described, such as for example velate astrocytes, perivascular astrocytes, marginal glia, tanycytes, and different types of ependymal glia (e.g., ependymocytes, choroid plexus cells, and retinal pigment epithelial cells) (Reichenbach and Wolburg 2009). (antiviralbiologic.com)
Human2
  • The two main proposed types of EGF-like domains are the human EGF-like (hEGF) domain and the complement C1r-like (cEGF) domain, which was first identified in the human complement protease C1r. (wikipedia.org)
  • Central questions are whether all astrocytes or just specific types share these functions and what the relevance is of these differences to human disease. (antiviralbiologic.com)
Viral2
  • Specifically, during HIV infection, the maturation state and abundance of DCs during infection is correlated with HIV viral load, disease progression, and immune dysregulation. (jscimedcentral.com)
  • Of particular importance is the DC-specific C-type lectin DC-SIGN, which is a strong HIV binding partner and enhances both viral replication and trans-infection. (jscimedcentral.com)
Molecular3
  • Animal models of polycystic kidney disease (PKD) have been invaluable in discovering and dissecting cellular and molecular pathways by which polycystic kidneys develop and by which progression of all types of PKD may be modified [ 1 ],[ 2 ]. (biomedcentral.com)
  • Astrocytes react to all types of CNS disease and insult by becoming reactive, a nonspecific but feature response which involves various morphological and molecular adjustments highly. (antiviralbiologic.com)
  • The transitional type is involved in molecular transport whereas the sarcoplasmic reticulum is primarily concerned with how to " manage" calcium ions. (biologyonline.com)
Role2
  • Overall, these data suggest that LLT1-CD161 interactions play a novel and important role in B-cell maturation within the GC in humans. (ox.ac.uk)
  • Role of neutrophil extracellular la NETosis en las enfermedades infecciosas pulmonares. (bvsalud.org)
Calcium1
  • May participate in oocyte maturation via the regulation of calcium homeostasis. (enquirebio.com)
Domain1
  • It has three parts: (i) V-type Ig domain with sia -binding site, (ii) C1-type Ig domain, (iii) C2-type Ig domain. (biomedcentral.com)
Demonstrate1
  • Inhibition of IL-1β signaling by IL-1 receptor antagonist IL-1RA or IL-1β antibody demonstrate encouraging therapeutic effect in type 2 diabetes6,7. (docksci.com)
Tissues1
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
Immune1
  • The mammalian innate immune system recognizes and responds to different types of pathogens in order to protect the host through multiple signaling responses. (docksci.com)
State2
  • Activating C-type lectin receptor NKG2D Carboxyamidotriazole identifies the modified self-state of contaminated or changed activates and cells NK-cell cytolytic activity. (biospraysehatalami.com)
  • As a result, the pathologic cells of LCH have been hypothesized to represent Langerhans cells in a state of arrested maturation. (medscape.com)
Diabetes6
  • 1 www.nature.com/scientificreports/ destruction in type 1 diabetes and increases the risk for type 2 diabetes by inducing insulin resistance4. (docksci.com)
  • Importance: Individuals with prediabetes are at increased risk of developing type 2 diabetes, chronic kidney disease, and cardiovascular disease. (cdc.gov)
  • The incidence and prevalence of type 2 diabetes in the US adolescent population have increased in the last decade. (cdc.gov)
  • Therefore, it is important to monitor the prevalence of prediabetes and varying levels of glucose tolerance to assess the future risk of type 2 diabetes in the youngest segment of the population. (cdc.gov)
  • Adolescents and young adults with prediabetes also present an unfavorable cardiometabolic risk profile, putting them both at increased risk of type 2 diabetes and cardiovascular diseases. (cdc.gov)
  • Common examples for such diseases include coronary heart disease, type 2 diabetes or cancer. (cdc.gov)
Domains1
  • The lost cysteines of the common ancestor differ between cEGF- and hEGF-like domains and hence these types differ in their disulfide linkages. (wikipedia.org)
Keywords1
  • solid course="kwd-title" Keywords: protoplasmic, fibrous, reactive astrocytes, examine, GFAP, glial scar tissue Astrocytes will be the most abundant nonneuronal cell type within the mind. (antiviralbiologic.com)
High1
  • A total number of 12 N- glycan structures were deduced from Arabidopsis , including 4 high-mannose types and 8 complex types. (chinbullbotany.com)