• organ
  • While single organ manifestations have been described already more than 100 years ago, a clear description and nomenclature of this disease have been achieved in the past 10 years. (biomedcentral.com)
  • The patient underwent a series of organ biopsies over the years including resections of the orbital pseudotumor and left submandibular salivary gland, as well as biopsies of ocular muscles. (biomedcentral.com)
  • Here these two classifications are merged and expanded to include the many forms of secondary, i.e. reactive hypereosinophilia/eosinophilia, disorders and also includes another subtype, organ-restricted hypereosinophilias, a disorder in which eosinophil-mediated tissue damage is restricted to one organ and is often but not always associated with increased blood eosinophil counts. (wikipedia.org)
  • Men with IgG4-related prostatitis may have similar findings to those that are frequently, but not always, seen in other organ manifestations of IgG4-related disease, such as elevated blood levels of IgG4, IgE and eosinophils. (wikipedia.org)
  • lesions
  • The inflammatory lesions in Küttner's tumor may occur on one side (unilateral) or both sides (bilateral), predominantly involving the submandibular gland, but is also known to occur in other major and minor salivary glands, including the parotid gland. (wikipedia.org)
  • symptoms
  • in 1996 reported the following symptoms in order of frequency of occurrence: Bone pain Retroperitoneal fibrosis Diabetes insipidus Exophthalmos Xanthomas Neurological signs (including Ataxia) Dyspnea caused by interlobular septal and pleural thickening. (wikipedia.org)
  • The initial symptoms of RCC often include blood in the urine (occurring in 40% of affected persons at the time they first seek medical attention), flank pain (40%), a mass in the abdomen or flank (25%), weight loss (33%), fever (20%), high blood pressure (20%), night sweats and generally feeling unwell. (wikipedia.org)
  • kidney
  • This can include kidney, skin, brain and lung involvement, and less frequently retroorbital tissue, pituitary gland and heart involvement is observed. (wikipedia.org)
  • inflammatory
  • Encasement of the glandular ducts in thick fibrous tissues, as a result of chronic presence of inflammatory infiltrate in that area - a condition known as periductal fibrosis. (wikipedia.org)
  • obstruction
  • The consequences of vessel and airway obstruction include chylous fluid accumulations, hemoptysis, airflow obstruction and pneumothorax. (wikipedia.org)
  • structures
  • The local affectation is caused by the entrapment of the retroperitoneal structures, mainly the ureters (60-100%) causing obstructive uropathy and renal failure with abdominal/lumbar pain, oedema, varicocele, dysuria, oligoanuria, deep venous thrombosis, etc. (eurorad.org)
  • liver
  • manifestations of carcinoid syndrome do not occur until there are metastases to the liver or when the cancer is accompanied by liver failure (cirrhosis). (wikipedia.org)
  • Carcinoid tumors arising in the bronchi may be associated with manifestations of carcinoid syndrome without liver metastases because their biologically active products reach the systemic circulation before passing through the liver and being metabolized. (wikipedia.org)
  • usually
  • US: RPF is usually identified as a hypoechoic or anechoic, well-demarcated although irregularly contoured retroperitoneal mass. (eurorad.org)
  • Usually, on a CT scan, a spider-like/crab-like change is visible in the mesentery due to the fibrosis from the release of serotonin. (wikipedia.org)
  • heart
  • The syndrome includes flushing and diarrhea, and less frequently, heart failure, emesis and bronchoconstriction. (wikipedia.org)