Males x chromosome. Medical search. Frequent questions

The Y chromosome is one-third of the size of its counterpart, and it carries around 55 genes that are mostly to deal with being male, while the X chromosome represents about 5% of a cell's total DNA and likely contains over 900 genes that are essential for proper development and cell viability. (worldhealth.net)
The Y chromosome contains the blueprints for certain genes, based on the way they are expressed in normal cells within the bladder lining a scoring system was developed to measure the loss of the Y chromosome in cancers. (worldhealth.net)
The gene is a non-coding sequence made of RNA found in the cells of placental mammals that plays a key role in the silencing of genes on X chromosomes. (sciencealert.com)
Another possibility is there are some important genes on the X chromosome that, when silenced, enable the cancer to grow. (sciencealert.com)
The strong suppression of recombination in the pericentromeric regions and co-segregation of race specific chromosomes involved in the long chains would be expected to lead to linkage disequilibrium between genes located there. (preprints.org)
Identifying genes on each chromosome is an active area of genetic research. (medlineplus.gov)
Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. (medlineplus.gov)
Chromosome 15 likely contains 600 to 700 genes that provide instructions for making proteins. (medlineplus.gov)
However, some genes on this chromosome, including some of those in the 15q11.2-q13.1 region, are turned on (active) only on the maternal copy. (medlineplus.gov)
Consequences of this recently transformed sex chromosome system include Y-like degeneration and gene amplification on the male-specific X, expression of ancestral Y-linked genes in females, and X inactivation of the male-specific chromosome in male somatic cells. (pdx.edu)
Chromosome 9 likely contains between 800 and 1,300 genes. (news-medical.net)
Genes on chromosome 9 are among the estimated 20,000 to 25,000 total genes in the human genome. (news-medical.net)
Compared to the X, the Y chromosome also carries far fewer protein-coding genes. (newzlab.com)
The repetitions in the Y's genes in this area can sometimes disrupt male fertility. (newzlab.com)
Overall, the combined research determined that this specific Y chromosome has 106 protein-coding genes. (newzlab.com)
In this context, scientists, who mapped 50 percent of the Y chromosome in 2003 , mapped a total of 62 million DNA base pairs , marking 30 million new base pairs , and discovered 41 new genes responsible for protein production, Daily Mail reported. (turkiyenewspaper.com)
Rissman's team wanted to find out of if genes -- or, to be more precise, sex chromosomes -- could influence sex-specific behavior directly, i.e. beyond what could be expected from the pre-natal flow of hormones. (crossdreamers.com)
genes appears to make males more -- not less -- masculine. (crossdreamers.com)
See my presentation of the debate on genes, chromosomes, hormones and sex identity for more information on the roles of chromosomes. (crossdreamers.com)
Lighter bands on chromosomes called euchromatin where genes are expressed. (mindmeister.com)
Short stature in each of these patients has been explained by the effect of imprinting of growth-related genes on maternal chromosome 7. (nih.gov)
In skin, muscle, fat and more tissues, genes behave differently in men and women. (theconversation.com)
The human Y chromosome has retained only 3% of its ancestral genes. (theconversation.com)
The Y chromosome, that little chain of genes that determines the sex of humans, is not as tough as you might think. (theconversation.com)
How and why males exist in evolutionary overdrive despite carrying essentially the same genes as females has long puzzled scientists. (nbcnews.com)
The mode of inheritance in males involves simpler genetic architecture that does not include as many interactions between genes as could be involved in female inheritance. (nbcnews.com)
Of those genes, about 7,600 have different expressions (alleles) that do different jobs in males and females. (nbcnews.com)
In flies and humans, thousands of genes made up of DNA are packaged into tiny units called chromosomes. (nbcnews.com)
Many genes are found on the X chromosome, whereas few are associated with the Y chromosome. (nbcnews.com)
For female fruit flies, the X-chromosome genes can come in two flavors called alleles that not only interact with each other but also with other genes. (nbcnews.com)
We find direct evidence that the expression of the genes on the X has this covering behavior in females whereas in males they're out in the open," said study team member Lauren McIntyre, also of UF. (nbcnews.com)
Having one X means your genes are more open to selection in males," UF researcher Marina Telonis-Scott said in a telephone interview. (nbcnews.com)
While not as prominent a trend, they also found a similar pattern in so-called autosomal genes, which are those found on any chromosome save the sex chromosomes. (nbcnews.com)
Many of the fruit-fly autosomal genes, however, did work in concert with genes located on the X chromosome. (nbcnews.com)
Both hemophilia A and B are inherited in the same way, because both the genes for factor VIII and factor IX are located on the X chromosome (chromosomes are structures within the body's cells that contain the genes). (cdc.gov)
There are no genes for clotting factors on the Y chromosome. (cdc.gov)
Association studies performed in two independent groups revealed a locus on chromosome 20 (not near any known genes) as well as the androgen receptor on the X chromosome. (bernsteinmedical.com)
Do Genes Cause Male Pattern Baldness And, If So, Which Ones? (bernsteinmedical.com)
What are the genes that cause male pattern baldness? (bernsteinmedical.com)
It has long been thought that the genes for common baldness come from the mother side of the family - explaining why a male whose maternal grandfather is bald is more likely to lose his hair than if his own father were bald. (bernsteinmedical.com)
Genes also determine why some illnesses run in families and whether babies will be male or female. (kidshealth.org)
The genes code for different traits, such as eye color, body type, or male or female sex. (kidshealth.org)
It shows where the genes are located on the chromosomes. (kidshealth.org)
These conditions are described as genetic diseases because a defect in one or more genes or chromosomes leads to a pathological condition. (who.int)
Testing for chromosome and gene abnormalities Chromosomes are structures within cells that contain a person's genes. (msdmanuals.com)

Walsh, of UVA's Division of Cardiovascular Medicine and the Robert M. Berne Cardiovascular Research Center, and his team used cutting-edge CRISPR gene-editing technology to develop a special mouse model to better understand the effects of Y chromosome loss in the blood. (neurosciencenews.com)
A new UCLA study has identified a gene on the Y chromosome that protects against pulmonary hypertension - a rare but fatal disease that occurs four times more often in women than men. (uclahealth.org)
To conduct the experiment, which was done in mice, researchers silenced each gene, one by one, in the Y chromosome to tease out which gene is linked to the development of pulmonary hypertension. (uclahealth.org)
After observing each gene's function, the researchers found that the gene, Uty, stops an inflammatory pathway in the lungs in male mice and thereby halts the development of the disease. (uclahealth.org)
Article: Y-Chromosome Gene, Uty, Protects Against Pulmonary Hypertension by Reducing Proinflammatory Chemokines. (uclahealth.org)
Analyzing thousands of genomes representing more than 30 different cancers, researchers found the gene responsible for silencing the X chromosome - known as X-inactive specific transcript, or XIST - is highly expressed in a wider variety of cancerous tissues than they'd ever suspected. (sciencealert.com)
The genome of M. oregoni elucidates the processes that shape the gene content and dosage of mammalian sex chromosomes and exemplifies a rare case of plasticity in an ancient sex chromosome system. (pdx.edu)
Because the affected gene is on the X chromosome, girls are carriers of the mutant gene but develop the disease only very rarely (one in about 50 million). (news-medical.net)
It was stated that the discovery, which is still in the early stages, may allow the solution of diseases such as some types of cancer and infertility in men with gene therapy . (turkiyenewspaper.com)
We show that although the nascent Y chromosome encompasses nearly half of the linkage group, there has been no perceptible degradation of Y chromosome gene content or activity. (nature.com)
The dominant theoretical model for the early stages of sex chromosome evolution 3 , 4 , 5 predicts that recombination will be selected against in the region between a sex determining gene and a nearby locus with alleles of sex-specific effect. (nature.com)
If that particular gene gives the male a boost in terms of sexual selection, say a gene responsible for fluffier feathers, the gene would be selected for in the game of natural selection over successive generations. (nbcnews.com)
But if the gene is no good for males, it would get selected against over time. (nbcnews.com)
Caenorhabditis elegans gene him-8 , high Incidence of Males, encoding HIM-8 like family member. (nih.gov)
[4] In the first stages of embryonic development, male and female embryos are almost morphologically identical, however, eventually, due to the expression of the sex-determining gene, on the Y chromosome, the testes begin to develop. (wikibooks.org)
So far, the genetic studies for androgenetic alopecia (AGA) have not revealed identification of a particular gene other than the androgen receptor, as well as the two candidate regions on chromosomes 3 and 20. (bernsteinmedical.com)
The first is on the Androgen Receptor (AR) gene carried on the x-chromosome and the second is a non-sex chromosome 20p11. (bernsteinmedical.com)
This observation was recently supported by the discovery of the androgen receptor (AR) gene which resides on the X-chromosome. (bernsteinmedical.com)
Mutations in the recently identified MEN1 gene at chromosome 11q13 have been found in parathyroid tumors of nonfamilial pHPT. (lu.se)
Studies have also suggested that late-onset Alzheimer risk may be higher in women with one or more copies of the APOE ε4 gene, but this gene may have a comparatively lower impact on men. (medscape.com)

Researchers at Baylor College say they've found the genetic reason for two common male reproductive tract birth defects in a genome-wide study. (medicaldaily.com)
In genetic males, the silencing of the X chromosome is rare but not unknown. (sciencealert.com)
An isodicentric chromosome contains mirror-image segments of genetic material and has two constriction points (centromeres), rather than one centromere as in normal chromosomes. (medlineplus.gov)
In people with an isodicentric chromosome 15, cells have the usual two copies of chromosome 15 plus the two duplicated copies of the segment of genetic material in the isodicentric chromosome, for a total of four copies of the duplicated segment. (medlineplus.gov)
In these cases, cells have two copies of chromosome 15, one of which has an extra copy of the segment of genetic material, for a total of three copies of the duplicated segment. (medlineplus.gov)
Chromosome 15q duplication is an extremely rare genetic disorder in which there is an excess copy of a segment of DNA found on the long ("q") arm of human chromosome 15. (wikipedia.org)
Although previous studies have pointed out that men lose some or all of their genetic material as they age, scientists have not been able to determine the cause-and-effect pattern of this phenomenon. (turkiyenewspaper.com)
evaluate the current evidence regarding different aspectsÂ (Epidemiological, histological, physiological and genetic) of male infertilityÂ caused by Y-chromosome microdeletion. (imed.pub)
Loss of recombination between sex chromosomes often depletes Y chromosomes of functional content and genetic variation, which might limit their potential to generate adaptive diversity. (scilifelab.se)
Using linked-read sequencing on multiple P. parae females and males of all five morphs, we find that the genetic architecture of the male morphs evolved on the Y chromosome after recombination suppression had occurred with the X. Comparing Y chromosomes between each of the morphs, we show that, although the Ys of the three minor morphs that differ in colour are highly similar, there are substantial amounts of unique genetic material and divergence between the Ys of the three major morphs that differ in reproductive strategy, body size and mating behaviour. (scilifelab.se)
Cytogenetic and molecular genetic studies have shown frequent losses on the long arm of chromosome 14 in different types of human gliomas. (nih.gov)
For the genetic algorithm, see Chromosome (genetic algorithm) . (wikipedia.org)
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. (wikipedia.org)
Wilhelm Roux suggested that each chromosome carries a different genetic configuration , and Boveri was able to test and confirm this hypothesis. (wikipedia.org)
The 2017 Prime Minister's Science Prize winner is genetic researcher Professor Jenny Graves, well known for her 2002 suggestion that the male Y chromosome will self-destruct. (theconversation.com)
New research on fruit flies, detailed online last week in the journal Proceedings of the National Academy of Sciences, finds males have fewer genetic obstacles to prevent them from responding quickly to selection pressures in their environments. (nbcnews.com)
And the reason males are genetic simpletons, it turns out, is sex. (nbcnews.com)
The researchers suggest this uncomplicated (compared with females) genetic pathway allows males to respond at the drop of a hat to the pressures of sexual selection. (nbcnews.com)
Some genetic diseases, such as haemophilia, are carried on the X-chromosome (these X-linked disorders occur mainly in men). (who.int)

Biological gender is determined by chromosomes that carry our DNA, males have XY chromosomes while females have XX. (worldhealth.net)
Randomly turning off an extra X is the body's way of balancing the chromosome dosage of both males and females. (sciencealert.com)
C15 trisomy affects twice as many males as females. (wikipedia.org)
The sex chromosome karyotype of the creeping vole ( Microtus oregoni ) represents a long-standing anomaly, with an X chromosome that is unpaired in females (X0) and exclusively maternally transmitted. (pdx.edu)
Male fetuses are exposed to testosterone from 4 weeks old, while females are not. (crossdreamers.com)
While these XX male mice had the same level of testosterone as normal XY mice, they displayed more masculine sexual behaviours - mounting females more often and ejaculating more frequently. (crossdreamers.com)
Researchers find that males can respond quicker than females to sexual selection, resulting in glitzier garbs like the male peacock's tail feather, which outshows any drab peahen. (nbcnews.com)
Evolution speeds along in the males compared to females. (nbcnews.com)
The idea that males evolve more quickly than females has been around since 19th century biologist Charles Darwin observed the majesty of a peacock's tail feather in comparison with those of the drab peahen. (nbcnews.com)
In this case, the females have two X chromosomes (XX) and males, XY. (nbcnews.com)
females have two X chromosomes (XX) and males have one X chromosome and one Y chromosome (XY). (cdc.gov)
Males and females produce all three of these hormones, but in different concentrations within the blood: females have higher levels of oestrogen and progesterone, whilst males have higher levels of testosterone. (wikibooks.org)
Despite the undeniable biological truths which separate males from females, scientific data which seeks to prove gender as biological is often flawed. (wikibooks.org)
22 pairs of chromosomes are the same in males and females. (kidshealth.org)

The database of CHROMOSOMAL VARIATION IN MAN consists of a systematic collection of important citations from the world's literature reporting on all common and rare chromosomal alterations, phenotypes, and abnormalities in humans. (genetic.org)
Humans normally have 46 chromosomes in each cell, divided into 23 pairs. (medlineplus.gov)
Humans typically have 23 pairs of chromosomes, 46 in total. (newzlab.com)
The smallest chromosome in humans, the men-specific Y chromosome, has just been sequenced after considerable hurdles. (theconversation.com)
[2] According to Oxford Dictionary, sex is defined as, "either of the two main categories (male and female) into which humans and most other living things are divided on the basis of their reproductive functions. (wikibooks.org)

Is the Subject Area "Chromosome pairs" applicable to this article? (plos.org)
Two copies of chromosome 15, one copy inherited from each parent, form one of the pairs. (medlineplus.gov)
Chromosome 15 spans more than 102 million DNA building blocks (base pairs) and represents more than 3 percent of the total DNA in cells. (medlineplus.gov)
Chromosome 9 is made up of about 140 million DNA building blocks (base pairs) and represents approximately 4.5 percent of the total DNA in cells. (news-medical.net)
Researchers from the Telomere-to-Telomere (T2T) Consortium on behalf of the National Human Genome Research Institute in the USA have completed the mapping of the Y sex chromosome , which is the only one of the 23 pairs of chromosomes found in a healthy individual . (turkiyenewspaper.com)
In order to understand the dynamics of the guppy Y chromosome, we used linked-read sequencing to assess Y chromosome evolution and diversity across upstream and downstream population pairs that vary in predator and food abundance in three replicate watersheds. (scilifelab.se)
Except for certain cells (for example, sperm and egg cells or red blood cells), every human cell contains 23 pairs of chromosomes, for a total of 46 chromosomes. (msdmanuals.com)
There are 22 pairs of chromosomes that are not sex chromosomes (called nonsex chromosomes, numbered chromosomes, or autosomal chromosomes) and one pair of sex chromosomes. (msdmanuals.com)

While women have two X chromosomes, men have an X and a Y. But many men begin to lose their Y chromosome in a fraction of their cells as they age. (neurosciencenews.com)
Typically, men have one X and one Y chromosome on the 23rd pair while women have two X chromosomes. (uclahealth.org)

Tortoiseshell male cats do, however, occur at a low frequency among tortoiseshell cats because of chromosome aberrations similar to the Klinefelter syndrome in man: the extra X chromosome of a 39,XXY karyotype introduces the possibility of an orange and a non-orange allele which produce the mixture of orange and non-orange coat spotting known as tortoiseshell. (karger.com)
Genic differentiation, together with the high frequency of pairing aberrations in male carriers of the long chains, might contribute to maintenance of the narrow hybrid zone. (preprints.org)

Trisomy of sex chromosomes is compatible with life, but will cause phenotypic abnormalities. (mindmeister.com)
Defective antibody production and low circulating numbers of B cells were described in some female infants and in males in whom no Btk abnormalities were detected. (medscape.com)
Sex chromosome abnormalities may be caused by full or partial deletions or duplications of sex chromosomes. (msdmanuals.com)
Abnormalities can also occur when a person is missing part of a sex chromosome (called a deletion). (msdmanuals.com)
Sex chromosome abnormalities are common and cause syndromes that are associated with a range of physical and developmental problems. (msdmanuals.com)
Down Syndrome (Trisomy 21) Down syndrome is a chromosome disorder caused by an extra chromosome 21 that results in intellectual disability and physical abnormalities. (msdmanuals.com)
Detection and characterization of male sex chromosome abnormalities in the UK Biobank study. (bvsalud.org)

Our results reveal the complex interplay between recombination suppression and Y chromosome divergence at the earliest stages of sex chromosome divergence. (scilifelab.se)

In normal mammal cells, the X chromosome is only muted when a female cell has a pair of Xs to choose from. (sciencealert.com)
Sex chromosomes evolve once recombination is halted between a homologous pair of chromosomes. (nature.com)
Sex chromosomes are typically thought to evolve as recombination is halted between a homologous pair of chromosomes in one sex. (nature.com)
One pair of these is called the sex chromosome. (nbcnews.com)
The 23rd pair - the sex chromosomes - determines the sex of the baby. (kidshealth.org)
A pair of X and Y chromosomes (XY) results in a male, and a pair of X and X chromosomes (XX) results in a female. (msdmanuals.com)

The guppy sex chromosomes show an extraordinary diversity in divergence across populations and closely related species. (scilifelab.se)
Based on our population-specific genome assemblies, we first confirmed and extended earlier reports of two strata on the guppy sex chromosomes. (scilifelab.se)
Even though the guppy sex chromosomes are a classic model for the study of sexual conflict and sex chromosome divergence, little is actually known about the pattern of divergence between the X and Y chromosomes. (nature.com)

Chromosome analysis using RBA-banding consistently revealed a 39,XXY karyotype. (karger.com)

It could have been very chaotic, but instead, nearly half of the chromosome is made of alternating blocks of two specific repeating sequences known as satellite DNA," he added. (newzlab.com)

All mutations were mapped to a chromosome region and all were archived as cryopreserved sperm from heterozygous males. (jax.org)
While these mice have been studied previously, the research team noticed that mice with certain MCM mutations had drastically more male pups than female pups. (nih.gov)
The researchers think that higher levels of micronuclei (fragments of chromosomes ejected from the main nucleus) caused by MCM mutations may trigger a specific DNA-sensing pathway called STING, which is the likely culprit behind the lethal inflammation in female embryos. (nih.gov)

Dup15q syndrome arises only if the chromosome abnormality occurs on the copy of the chromosome inherited from the mother (the maternal copy). (medlineplus.gov)
The most common chromosome abnormality that leads to 15q11.2-q13.1 duplication, occurring in about 80 percent of people with dup15q syndrome, is called an isodicentric chromosome 15. (medlineplus.gov)
Syndromes that are caused by a sex chromosome abnormality are less severe than those caused by a nonsex chromosome abnormality. (msdmanuals.com)
Turner Syndrome Turner syndrome is a sex chromosome abnormality in which girls are born with one of their two X chromosomes partially or completely missing. (msdmanuals.com)

We show that M. oregoni has lost an independently segregating Y chromosome and that the male-specific sex chromosome is a second X chromosome that is largely homologous to the maternally transmitted X. Both maternally inherited and male-specific sex chromosomes carry fragments of the ancestral Y chromosome. (pdx.edu)

The following chromosomal conditions are associated with changes in the structure or number of copies of chromosome 15. (medlineplus.gov)
15q13.3 microdeletion is a chromosomal change in which a small piece of chromosome 15 is deleted in each cell. (medlineplus.gov)

To confirm that the differences were a result of a hidden factor on the X chromosome and not the lack of a Y chromosome, the team compared XY male mice with XXY male mice, which carry an extra X chromosome. (crossdreamers.com)

This study for the first time makes a connection that has never been made before between loss of the Y chromosome and the immune system's response to cancer," says Professor Dan Theodorescu, the corresponding author from Cedars-Sinai Medical Center. (worldhealth.net)
We discovered that loss of the Y chromosome allows bladder cancer cells to elude the immune system and grow very aggressively. (worldhealth.net)
The loss of the Y chromosome has also been observed in several types of diseases which includes 10-40% of bladder cancers, it is linked with cardiovascular disease and Alzheimer's disease, and it may help to explain why women generally live longer than men. (worldhealth.net)
Those with loss of the Y chromosome were found to have a poorer prognosis in the first group and much better overall survival rates in the second group. (worldhealth.net)
Our investigators postulate that loss of the Y chromosome is an adaptive strategy that tumor cells have developed to evade the immune system and survive in multiple organs," said Shlomo Melmed, MB, ChB, executive vice president of Academic Affairs and dean of the Medical Faculty at Cedars-Sinai. (worldhealth.net)
Study reports that age-related loss of the Y chromosome in men is linked to heart muscle scarring and an increased risk of heart failure. (neurosciencenews.com)
Loss of the Y chromosome does not occur in male reproductive cells, so it is not inherited by the children of men who exhibit Y chromosome loss. (neurosciencenews.com)

Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India. (physiciansweekly.com)
SurveysÂ also show changes in the male hormone physiology varying the levelsÂ of testosterone/LH/FSH as well as modifying the gonadal morphologyÂ in individuals affected by Y-chromosome microdeletion. (imed.pub)

Crossing over is reduced in the No 1 bivalent with only a rare chiasma being seen in the inverted region at metaphase I. Males heterozygous for a pericentric inversion in chromosome 1 appear to be at severe risk for infertility brought about by spermatogenic disturbance. (bmj.com)
More research is needed focusing on possible deletionsÂ that the Y-chromosome may suffer, giving emphasis on their clinicalÂ outcomes and correlations with infertility. (imed.pub)
Infertility in men can result from deficiencies in sperm formation, concentration, or transportation. (medscape.com)
Testicular biopsy is indicated in azoospermic men with a normal-sized testis and normal findings on hormonal studies to evaluate for ductal obstruction, to further evaluate idiopathic infertility, and to retrieve sperm. (medscape.com)
Of the mutant lines established, about 75% exhibited a male infertility phenotype only, almost 10% exhibited female infertility only, and about 15% exhibited infertility of both sexes. (jax.org)

For example, women may be at higher risk than men due to genetics or hormones. (medscape.com)

Using immunolocalisation of the meiotic proteins, we examined chromosome pairing and recombination in males from the hybrid zone. (preprints.org)
The consequences of such nonrandom aspects of nuclear structure for chromosome behavior on premeiotic and meiotic spindles are discussed. (rupress.org)

this evidence was gained from ultrastructural reconstruction analyses of the arrangement of chromosomes in germ line nuclei (prophase nuclei in spermatogonia and spermatocytes) of males heterozygous for an X-autosome chromosome translocation. (rupress.org)
Some girls and women who are heterozygous have bleeding symptoms, but usually they are milder than those of boys and men with hemophilia. (cdc.gov)
In rare cases, a female who is heterozygous can have bleeding symptoms that are just as serious as those of a male with hemophilia. (cdc.gov)
A father who has hemophilia passes his only X chromosome down to all of his daughters, so they will always get his hemophilia allele and be heterozygous (carriers). (cdc.gov)

Pericentric inversion in human chromosome 1 and the risk for male sterility. (bmj.com)
A pericentric inversion in chromosome 1 of a severely oligospermic human male is reported. (bmj.com)
The scientists also looked at the effects of Y chromosome loss in human men. (neurosciencenews.com)
Dr. Cunningham hopes these findings will inspire researchers to study both male and female animals, cell lines, or human subjects to determine how diseases progress in different sexes. (uclahealth.org)
The human Y chromosome, the determinant of male sex, has finally been completely sequenced. (newzlab.com)
The Y chromosome is by far the most difficult human chromosome to sequence and assemble. (turkiyenewspaper.com)
In 2020, the National Human Genome Research Institute completed the mapping of the X sex chromosome , which was prioritized for its link to diseases such as hemophilia, chronic granulomatosis, and Duchenne Muscular Dystrophy (DMD) . (turkiyenewspaper.com)
Moreover, this definitely says nothing about the sex identity of XXY human male bodied persons. (crossdreamers.com)
This tendency has apparently also been reported among human XXY males . (crossdreamers.com)
In other words: Among XXY human male bodied persons the condition can lead to (1) more male typical sexual behavior in some cases and (2) a female sex identity in others. (crossdreamers.com)
This tells me that there is no one to one relationship between men having two X chromosomes and being masculine in the human sense of the word. (crossdreamers.com)
Paternal isodisomy for human chromosome 7 may have no phenotypic effect on growth. (nih.gov)
The human Y chromosome could disappear over time, putting our species in jeopardy. (theconversation.com)

Because of this translocation, the maternal and paternal chromosome sets are distinguishable, so it is possible to demonstrate that (a) the two haploid chromosome sets occupy distinct maternal and paternal nuclear compartments and that (b) nuclei are oriented so that the two haploid chromosome sets have consistent relationships to a well-defined cellular axis. (rupress.org)
DISCUSSION: Although this is the largest cytogenetic study of male commercial airline pilots to date of which the authors are aware, future studies will need additional highly exposed pilots to better assess the translocation- cosmic radiation relation. (cdc.gov)

Despite longstanding assumptions that sex chromosome recombination suppression is achieved through inversions, we find no evidence of inversions associated with either Stratum I or Stratum II. (scilifelab.se)
Instead, we observe a remarkable diversity in Y chromosome haplotypes within each population, even in the ancestral Stratum I. This diversity is likely due to gradual mechanisms of recombination suppression, which, unlike an inversion, allow for the maintenance of multiple haplotypes. (scilifelab.se)

Otto Bütschli was the first scientist to recognize the structures now known as chromosomes. (wikipedia.org)
Inside each cell, DNA is tightly wrapped together in structures called chromosomes . (kidshealth.org)

We developed a method for preparing male chromosomes from sea urchin hybrid andromerogones created with cryopreserved sperm. (bioone.org)
The andromerogones for 5 sperm species showed a half of their respective diploid chromosome numbers without chromosome elimination. (bioone.org)
This method is applicable for analysis of the haploid male chromosome complement in sea urchin species for which only sperm can be obtained. (bioone.org)
One key area of the Y chromosome that was decoded is known to affect sperm production. (newzlab.com)
He proposed that sperm had key differences based on the sex chromosome they carried - X or Y. (medicalnewstoday.com)
The basic theory behind the Shettles method is that people could use the differences between male (Y) and female (X) sperm to manipulate the sex of the fetus. (medicalnewstoday.com)
Dr. Shettles stated he found differences between male and female sperm. (medicalnewstoday.com)
However, in a 2020 study , researchers found that the differences between male and female sperm were limited to the content of their DNA. (medicalnewstoday.com)
The egg and sperm each have one half of a set of chromosomes. (kidshealth.org)
The egg and sperm together give the baby the full set of chromosomes. (kidshealth.org)

Hageltorn M, Gustavsson I: XXY-trisomy identified by banding techniques in a male tortoiseshell cat. (karger.com)
Trisomy 21 → gain of an extra chromosome 21, results in Down's syndrome. (mindmeister.com)
May have trisomy of other chromosomes, eg. (mindmeister.com)
occur when a person is missing a whole sex chromosome (called monosomy) or has an extra sex chromosome (one extra is trisomy). (msdmanuals.com)

As the patient has normal stature, it is likely that the paternal chromosome 7 lacks the suggested maternal imprinting effect on growth. (nih.gov)

The deletion occurs on the q arm of the chromosome at a position designated q13.3. (medlineplus.gov)

Along with the fully sequenced chromosome, an additional 43 Y chromosomes, gathered from a diverse selection of males, were extensively sequenced. (newzlab.com)
The 'weird' male Y chromosome has finally been fully sequenced. (theconversation.com)

Nonrandom chromosome arrangements in germ line nuclei of Sciara coprophila males: the basis for nonrandom chromosome segregation on the meiosis I spindle. (rupress.org)
[5] In animal cells, chromosomes reach their highest compaction level in anaphase during chromosome segregation . (wikipedia.org)

Losing the male sex chromosome isn't just a phenomenon of aging for many men, but it could be putting them at risk for cancer according to a study published in the journal Nature that was conducted by researchers at Cedars-Sinai Medical Centre, Los Angeles. (worldhealth.net)
The researchers are working on developing a Y chromosome test to aid in the customization of immune checkpoint-inhibiting drugs. (worldhealth.net)
Next, the researchers reviewed data from two groups of men: one group had muscle-invasive bladder cancer and had their bladders removed but were not treated with an immune checkpoint inhibitor, while the other group participated in a clinical trial and was treated with an immune checkpoint inhibitor. (worldhealth.net)
The researchers report that in both cases, tumors with/without the Y chromosome grew at the same rate. (worldhealth.net)
In the new study, published in the American Journal of Respiratory and Critical Care Medicine, researchers aimed to further understand how the Y chromosome confers protection against the disease. (uclahealth.org)
Researchers debunk man flu based on a review of available evidence. (news-medical.net)
A group of researchers in the USA succeeded in mapping the Y sex chromosome. (turkiyenewspaper.com)

Loci of interests in the X-chromosome (DXS9895, GATA172D05 and DXS9898) were amplified in a single PCR with primers of published sequences (1-3). (astm.org)
Therefore, in this system, current models of sex chromosome evolution predict that recombination would be selected against between the sex determining locus and linked loci involved in colouration. (nature.com)
This process would shrink the pseudoautosomal region in favour of expanding X- and Y-specific regions, creating a male supergene on the Y chromosome containing multiple colouration loci and thereby resolving sexually antagonistic selection. (nature.com)
She had inherited only paternal alleles at 10 loci and was homozygous for another 10 chromosome 7 loci studied. (nih.gov)

Though under cover, the recessive allele kind of hitches a ride on the X chromosome and can be passed on to future generations. (nbcnews.com)
So in a female if you have a recessive allele that confers a sickness, it can be concealed within the two X's but if you've only got one, such as the male, you're more open to selection. (nbcnews.com)
This means that males only have one allele for factor VIII and one allele for factor IX. (cdc.gov)
Thus, if a male has a hemophilia allele on his only X chromosome, he will have the disorder. (cdc.gov)
A female with a hemophilia allele on one X chromosome usually has a normal allele on her other X chromosome that can produce normal clotting factor, so she has some protection against having hemophilia. (cdc.gov)
A female can also have hemophilia if she inherits hemophilia alleles from both of her parents or if she inherits one hemophilia allele and her other X chromosomes is missing or does not work properly. (cdc.gov)

Called sexual selection, the result is typically a showy male and a plain-Jane female. (nbcnews.com)

Nor does the behavior of XXY male mice say anything about how these mice feel about their sex identity. (crossdreamers.com)

93:655-669), I suggested that the meiosis I spindle does not play a direct role in the nonrandom sorting of chromosomes but that, instead, haploid sets are already separated in prophase nuclei well before the onset of spindle formation. (rupress.org)

It can occur in conditions where the chromosome is duplicated, such as in Klinefelter syndrome (where two or more X chromosomes accompany a Y chromosome). (sciencealert.com)
Males of the freshwater fish Poecilia parae occur as one of five discrete morphs, all of which shoal together in natural populations where morph frequency has been stable for over 50 years. (scilifelab.se)

We produced a highly contiguous male genome assembly, together with short-read genomes and transcriptomes for both sexes. (pdx.edu)
These results provide empirical support for longstanding models of sex chromosome catalysis, and suggest an important role for sexual selection and sexual conflict in genome evolution. (nature.com)

Yet, we do, in fact, see that some male cancers of diverse subtypes activate XIST and display features of X inactivation. (sciencealert.com)

DNA of the male-determining Y chromosome has been completely sequenced end-to-end, and it's just as weird as we expected. (theconversation.com)

Recombination frequency in the proximal regions of most chromosomes of all karyotypes was much lower than in the other regions. (preprints.org)

Extreme Y chromosome polymorphism corresponds to five male reproductive morphs of a freshwater fish. (scilifelab.se)
Altogether, our results suggest that the Y chromosome is able to overcome the constraints of recombination loss to generate extreme diversity, resulting in five discrete Y chromosomes that control complex reproductive strategies. (scilifelab.se)
ENU-mutagenesis of male mice was followed by a standard three-generation breeding scheme, with fertility testing of all G3 offspring in order to identify putative reproductive mutants. (jax.org)
In males, decreased general health status appears to be associated with impaired male reproductive health. (medscape.com)

The mammalian sex chromosome system (XX female/XY male) is ancient and highly conserved. (pdx.edu)
Excellent for biology classrooms - great for comparison with Eisco Labs Female Chromosome Smear, BS18100 (sold separately). (eiscolabs.com)
The predominant idea is that the difference between male and female behaviours is down to hormones," says Emilie Rissman at the University of Virginia in Charlottesville. (crossdreamers.com)
An estimated 15% of couples meet this criterion and are considered infertile, with approximately 35% due to female factors alone, 30% due to male factors alone, 20% due to a combination of female and male factors, and 15% unexplained. (medscape.com)
This article will use the terms "male," "female," or both to refer to sex assigned at birth. (medicalnewstoday.com)
As a result, the female should refrain from orgasming until after the male has ejaculated. (medicalnewstoday.com)
The female should orgasm before the male ejaculates. (medicalnewstoday.com)
The secret to why male organisms evolve faster than their female counterparts comes down to this: Males are simple creatures. (nbcnews.com)
Copy number changes mapping to chromosome 16 have been reported to be the most frequent alteration observed in female breast cancer and a loss on 16q has been shown to be associated with low grade and better prognosis. (johnshopkins.edu)
4%). Losses on 16q were thereby less often seen in male breast cancer than previously described in female breast cancer. (johnshopkins.edu)
In conclusion, copy number loss on 16q is less frequent in male breast cancer than in female breast cancer, providing further evidence that male breast cancer and female breast cancer are genetically different. (johnshopkins.edu)
The anti-inflammatory properties of testosterone appear to protect male mouse embryos from certain types of DNA damage and inflammation that are fatal to female mouse embryos, according to a recent NIH-supported study. (nih.gov)
determine whether a fetus becomes male or female. (msdmanuals.com)

The finding could also shed light on why diseases show up differently in men and women. (nbcnews.com)

Uniparental disomy for maternal chromosome 7 has been described in three patients with recessive disorders. (nih.gov)

A linkage between DNA markers on the X chromosome and male sexual orientation. (bvsalud.org)

Like it or not, evidence now shows that men and women differ genetically far more profoundly that we previously recognised. (theconversation.com)
And are men really closer genetically to chimpanzees than to women? (theconversation.com)
The flies were identical genetically, except for their sex chromosomes . (nbcnews.com)

[4] Before this happens, each chromosome is duplicated ( S phase ), and both copies are joined by a centromere , resulting either in an X-shaped structure (pictured above), if the centromere is located equatorially, or a two-arm structure, if the centromere is located distally. (wikipedia.org)

Family studies revealed both the androgen receptor locus on the X chromosome, as well as a new locus on chromosome 3q26. (bernsteinmedical.com)

We analyzed the chromosome complement of a fibroblast culture and did histological examinations of testicular tissue from a tortoiseshell male cat referred to us. (karger.com)
As no sign of spermatogenesis was detected, we conclude that this is a classic case of a sterile, male tortoiseshell cat with a 39,XXY chromosome complement. (karger.com)

To find out if sex chromosomes play a role in sex-specific behaviours beyond dictating which hormones are present, Rissman's team took advantage of a mutation in mice that causes the sex-determining region of the male Y chromosome to jump to a non-sex chromosome. (crossdreamers.com)
[3] The physiological distinctions between men and women include differences in chromosomes, sexual organs and hormones. (wikibooks.org)

Meiosis I in males of the Dipteran Sciara coprophila results in the nonrandom distribution of maternally and paternally derived chromosome sets to the two division products. (rupress.org)

Man-made radioactive atoms are produced either as a by-product of fission of uranium atoms in a nuclear reactor or by bombarding stable atoms with particles, such as neutrons, directed at the stable atoms with high velocity. (cdc.gov)

Divergence and Remarkable Diversity of the Y Chromosome in Guppies. (scilifelab.se)

The dearth of full loops at prophase in this patient, and in other pericentric inversion cases studied both in man and other species, raises the question of whether recombinant offspring might be rarer than anticipated on a theoretical basis owing to asynapsis or early heterologous synapsis across inverted segments. (bmj.com)

Fluorescence and Giemsa banding studies of the allocyclic X chromosome in embryonic and adult mouse cells. (wikidata.org)

Scientists previously observed that men who suffer Y chromosome loss are more likely to die at a younger age and suffer age-associated maladies such as Alzheimer's disease. (neurosciencenews.com)
As chromosome loss increased, the scientists found, so did the risk of death. (neurosciencenews.com)
Scientists from the Dana-Farber Cancer Institute have found some male cancer cells, those with X and Y chromosomes, show signs of having their X chromosome silenced. (sciencealert.com)
The X chromosome only got the full sequencing treatment three years ago , using a new form of tech that allowed scientists to read thousands - or even millions - of DNA bases in one go. (newzlab.com)
Even the most biologically oriented scientists admits that only 50 percent of what we do can be attributed to nature (as opposed to nurture), meaning that you should expect much more variation among men and women than among mice. (crossdreamers.com)

They conducted three analyses of data compiled from the UK Biobank, a massive biomedical database, and found that Y chromosome loss was associated with cardiovascular disease and heart failure. (neurosciencenews.com)
For instance, the authors sometimes found two X chromosomes in male cancer cells. (sciencealert.com)

Stratum I shows significant accumulation of male-specific sequence, consistent with Y divergence, and predates the colonization of Trinidad. (scilifelab.se)
Using replicate wild populations with differing levels of sexually antagonistic selection for colour, we also show that sexual selection leads to greater expansion of the non-recombining region and increased Y chromosome divergence. (nature.com)

Anatomy60

Organisms8

Diseases28

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment18

Psychiatry and Psychology2

Phenomena and Processes143

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena1

Information Science4

Health Care1

Genes45

Gene20

Genetic19

Females14

Humans5

Pairs8

Women have two X chromosomes2

Aberrations2

Abnormalities7

Stages of sex chromosome1

Pair6

Guppy sex chromosomes3

Karyotype1

Half of the chromosome1

Mutations3

Abnormality4

Homologous1

Chromosomal2

Extra X chromosome1

Loss of the Y chromosome7

Microdeletion2

Infertility5

Genetics1

Meiotic2

Heterozygous4

Human13

Translocation2

Recombination suppression2

Structures2

Sperm10

Trisomy4

Paternal chromosome1

Deletion1

Fully sequenced2

Segregation2

Researchers7

Loci4

Allele6

Typically1

Behavior1

Haploid1

Occur2

Genome2

Inactivation1

Completely sequenced1

Karyotypes1

Reproductive4

Female13

Differently in men and w1

Disorders1

Linkage1

Genetically3

Centromere1

Androgen1

Complement2

Hormones2

Meiosis1

Nuclear1

Guppies1

Prophase1

Embryonic1

Scientists5

Found2

Divergence2